Thank you for this: My TH-cam channel focuses on the Microbiome...but also the Lymph system. Lymph moves neurotransmitters and precursors from the gut to the brain and lymph nodes. The Lymph only moves by muscle movement (there is no pump like the heart). Sedentary older individuals appear to need to walk more. After all, we were designed as hunter/gatherers.(c)
For those with constipation problems, one way of alleviating it I found was sleeping on my left side, which helped the bowel movement down and thru the final section of the large intestinal tract. I had a couple of periods each lasting more than a week. No more. There was a stimulation factor I believe causally related to my water consumption. I practice regular periods of intermittent fasting with alternate periods of ketogenic fasting. I avoid going into full fasting mode but can without feelings of hunger if I want to lose weight. The problem w that, losing 30% of muscle mass as well. Regarding the gut biome, there are tens of thousands of viruses and bacteria making a home in our gut. I don't know which ones among them are toxic but I do know my routine gives my body's biome an opportunity to do a reset.
The best pre and probiotics is Microbiome Labs, Megaspore-biotic and Mega-prebiotoc. They have some excellent presentations on their website and you tube channel & the founder is interviewed many times on different you tube hosts channels. Be encouraged! 🌞
Great presentation!!! Zonulin levels can indicate how "leaky" your gut is. I found out my zonulin was too high and was given a glutamine powder supplement which made a surprising difference. I still have work to do, but this knowledge made a big difference for me, so I wanted to share.
you can stimulate the microbiome with infrared (cold) laser on the gut. There is a device called the PDCare laser made by SYMBYX in Sydney, Australia which has peer reviewed research published in BMC Neurology Journal in July 2021. It shows PD patients improving on all measures after 12 weeks of laser done at home….
If different forms of a-synuclein are assessed for metals content within the molecules, can zinc and copper that may be common in molecules of a-synuclein that are not yet mis-folded, be compared quantitatively for metals content in mis-folded? Pb can replace Zn in many molecules, especially if there is a Zn deficiency while also a contamination present of Pb. Is there research quantifying this in PD, AD, and other a-synucleinopathies?
When stress from illness, pregnancy, old age etc. causes added need for more calcium, the body gets it from the bone. The body does not recognize the lead differently from the calcium, so it comes out with the calcium to once again circulate in the soft tissues where it can have toxic effect just as the body is at its most vulnerable. Contrary to common opinion, lead DOES pass through skin, but for some reason it loses its affinity for the red blood cells when it enters through skin, so it does not show up as elevating the blood lead level that is the most common diagnostic test for lead poisoning, yet more has entered the body. Lead is an ACCUMULATIVE toxic substance, it builds up a body burden that increases many ailments. Reading all of the available research is difficult, but sobering, and I can see how accumulation is a very important part of driving declining health, faster than would be if more precautions were taken with sources of exposure. Lead often substitutes for metal atoms that form the focal points of metalloproteins, making those essential proteins and enzymes dysfunctional because they no longer fold properly to get their physiologic job done. Now, glyphosate has become a co-contaminant adversely affecting many of the same physiologic pathways at mechanistic levels. Both lead and glyphosate can interfere with protein folding, having vast implications for disease causation both additive and synergistic. It is important to read the literature on both IMHO.
There's an NIH.gov study done on Bio-Kult Mind (which is a probiotic from the UK) which showed encouraging results with PD (at least that was my non-expert impression)
I'm not sure what you're saying is accurate. Usually these probiotics that include lactobacillus are encouraged. And most of the sources say that. What is your source for saying that lactobacillus is not indicated with sinemet med?
I've found the "GI Map" stool test informative but needed to have someone who could really decipher the data and give me recommendations. Maybe there are other options out there...I'd be interested in knowing more!
I so glad the microbiome has been brought into the Parkinson community conversation
Thank you for this: My TH-cam channel focuses on the Microbiome...but also the Lymph system. Lymph moves neurotransmitters and precursors from the gut to the brain and lymph nodes. The Lymph only moves by muscle movement (there is no pump like the heart). Sedentary older individuals appear to need to walk more. After all, we were designed as hunter/gatherers.(c)
For those with constipation problems, one way of alleviating it I found was sleeping on my left side, which helped the bowel movement down and thru the final section of the large intestinal tract. I had a couple of periods each lasting more than a week. No more. There was a stimulation factor I believe causally related to my water consumption. I practice regular periods of intermittent fasting with alternate periods of ketogenic fasting. I avoid going into full fasting mode but can without feelings of hunger if I want to lose weight. The problem w that, losing 30% of muscle mass as well. Regarding the gut biome, there are tens of thousands of viruses and bacteria making a home in our gut. I don't know which ones among them are toxic but I do know my routine gives my body's biome an opportunity to do a reset.
Fasting and prebiotics help prevent damage to, and regeneration of, the gut lining.
Great Presentation! Very Helpful!
The best pre and probiotics is Microbiome Labs, Megaspore-biotic and Mega-prebiotoc. They have some excellent presentations on their website and you tube channel & the founder is interviewed many times on different you tube hosts channels. Be encouraged! 🌞
Great presentation!!!
Zonulin levels can indicate how "leaky" your gut is. I found out my zonulin was too high and was given a glutamine powder supplement which made a surprising difference. I still have work to do, but this knowledge made a big difference for me, so I wanted to share.
glutamine is the fuel for cancer cells
Many thanks ❤ this is a great information indeed
Love from Bangladesh ❤🎉
you can stimulate the microbiome with infrared (cold) laser on the gut. There is a device called the PDCare laser made by SYMBYX in Sydney, Australia which has peer reviewed research published in BMC Neurology Journal in July 2021. It shows PD patients improving on all measures after 12 weeks of laser done at home….
Amazing 😍🎉
where is it sold in the united states?
Thank you for the interesting lecture and experience.
Excellent!!
What is the mechanism of action of a-synuclein in the gut, before it becomes mis-folded?
Does co-existance indicate causation? Perhaps age increases probability with greater opportunity for exposure with additional time.
If different forms of a-synuclein are assessed for metals content within the molecules, can zinc and copper that may be common in molecules of a-synuclein that are not yet mis-folded, be compared quantitatively for metals content in mis-folded? Pb can replace Zn in many molecules, especially if there is a Zn deficiency while also a contamination present of Pb. Is there research quantifying this in PD, AD, and other a-synucleinopathies?
Please elaborate more
@@AkfaiyazulHuq
When stress from illness, pregnancy, old age etc. causes added need for more calcium, the body gets it from the bone. The body does not recognize the lead differently from the calcium, so it comes out with the calcium to once again circulate in the soft tissues where it can have toxic effect just as the body is at its most vulnerable. Contrary to common opinion, lead DOES pass through skin, but for some reason it loses its affinity for the red blood cells when it enters through skin, so it does not show up as elevating the blood lead level that is the most common diagnostic test for lead poisoning, yet more has entered the body. Lead is an ACCUMULATIVE toxic substance, it builds up a body burden that increases many ailments. Reading all of the available research is difficult, but sobering, and I can see how accumulation is a very important part of driving declining health, faster than would be if more precautions were taken with sources of exposure. Lead often substitutes for metal atoms that form the focal points of metalloproteins, making those essential proteins and enzymes dysfunctional because they no longer fold properly to get their physiologic job done. Now, glyphosate has become a co-contaminant adversely affecting many of the same physiologic pathways at mechanistic levels. Both lead and glyphosate can interfere with protein folding, having vast implications for disease causation both additive and synergistic. It is important to read the literature on both IMHO.
Mitochondrial dysfunction, especially in brain diseases, can be one result IMHO
What probiotics can we consume or take?
Excellent question!
Excellent question, Mark.
MegaSpore ?
There's an NIH.gov study done on Bio-Kult Mind (which is a probiotic from the UK) which showed encouraging results with PD (at least that was my non-expert impression)
Martha Carlin has developed a probiotic called Sugar Shift by Biotiquest which has strains that can help PD as well as ADHD
What about l-reuteri
How do I contact her
Mother Nature knew lol.
I know which probiotics should not be used when taking Sinamet. Lactobacillus
I'm not sure what you're saying is accurate. Usually these probiotics that include lactobacillus are encouraged. And most of the sources say that. What is your source for saying that lactobacillus is not indicated with sinemet med?
Can we test the microbiome? Thank you for your work!
I've found the "GI Map" stool test informative but needed to have someone who could really decipher the data and give me recommendations. Maybe there are other options out there...I'd be interested in knowing more!
I destroyed my whole body
Bad meat can trigger PD.