Clopidogrel, Prasugrel, Ticagrelor (antiplatelets)- the difference and when to use which one in ACS

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The above video is trying to explain the difference between 3 antilpletelets - Clopidogrel, Prasugrel, Ticagrelor- and when to use which one in ACS (STEMI and NSTEMI) - explained in causal manner by Cardiologist Dr Akhilesh Jain

[@TheICUChannel]

Hello members! I would love to hear your thoughts on this casual teaching and discussion style compared to the traditional PowerPoint presentations. Thinking of ICU case discussions also like this. Thank you! Yours , Dr Ankur

[@vaitheeshwaran_anand]

Yeah sir awesome want to hear More such things 🎇

[@kaushiksarkar8655]

Yes sir this style is great

[@pankajpunj-ch9ml]

Information is crisp and to the point , looks like "post rounds corridor talk" which you never forget ! Only negative point is the noise or distraction.

[@sharavanchakri6496]

Loved it sir ❤

[@diganthcd]

This is the best. A systematic teaching is needed only for writing exams.

[@swashbuckler2319]

1. DAPT used due to high risk of stent rethrombosis when only one agent was used. Clopidogrel was first, after discovery of clopidogrel resistance, we came up with Prasugrel and Ticagrelor
2. C/I to Prasugrel- Weight less than 60kg, Age more than 75 y/o, History of CVA (Increased risk of brain bleeds)
3. Ticagrelor can cause bronchospasm. Severe bronchospasm should prompt changing of Ticagrelor to other agent
4 . When planning for PCI (Rescue or elective), preference is to use Ticagrelor or Prasugrel for loading of patient with ACS
5. DAPT is to be for 1 year after stent placement. If patient is on Ticagrelor/Prasugrel, they should be on it for atleast 3 months. After three months, can consider converting to Clopidogrel if patient determined to have low risk of stent thrombosis, but should still continue DAPT for 1 year. If low risk, after 1 year, can convert to single antiplatelet agent for secondary prevention
6. Prasugrel only to be used if PCI is being planned. Ticagrelor can be used whether patient is getting PCI or if patient being planned for CABG. Ticagrelor is preferred if patient is getting CABG as half life is less, and can wear off quickly just prior to procedure
Take home:
1.Load MI patients with aspirin and clopidogrel
2. Angiogram to determine anatomy
3.If going for PCI, preference is for Prasugrel or Ticagrelor
4. If conservatively managed, can continue clopidogrel, or switch to Ticagrelor

[@balaramhazra7316]

@@swashbuckler2319 very good 👍

[@RNTEagle1]

If Going For CABG after angiography, will have to wait for 5 days after stopping Clopidogrel

[@MostaqueAhmed-z9c]

What's about anticoagulant

[@khanabualamkhan4800]

@@swashbuckler2319 thanks

[@ShivShivu-o8i]

I love the way sir explain everything with the history of antiplatelets🎉.....kudos to both of u ❤

[@TheICUChannel]

Glad you liked it

[@dr.mehediahmed2099]

Sir should be liked that!
Such a lovely Sir with full respect! 😊🤍🤍

[@priyankamahendrakar4634]

Proper utilisation of time and opportunity..Very good sir 🙏🏻

[@sabharwaljp962]

Sir, precisely explained. Pl keep soing Likewise ahead also. Love it Sir.

[@saurabhpatel8910]

Good explanation ❤

[@lovewithnature965]

Very nice 👍 very good information about antiplatlate

[@vcvc567]

Thank you sir, appreciate this style of teaching... expecting more such videos

[@abheekdas7595]

Excellent discussion.

[@rahulbajaj8395]

Highly informative.. Thanks

[@sujitroutray1]

Thank you for this, Dr. Ankur

[@malithprasanna9480]

Very effective short.. ❤

[@RamavatarSharma-q3p]

Excellent sir both of you

[@swapnilgarje8305]

Best for all doctor student physcian

[@krishvasa7644]

Excellent video sir! Thank you!!

[@TwinkalMistri]

Very informative shots
Thank you dr ankur

[@TheICUChannel]

Thank you and welcome

[@Simplensweett]

Good information. Very useful

[@shilpadesai9962]

Nice information, thanks

[@raeesansari770]

Very useful sir...❤

[@TheICUChannel]

Glad to hear that

[@chandrahaspatidar3273]

Society gets benefitted even when intellectuals do talk casually.

[@abudaniyal715]

Thanks

[@ajaynimbalkar8952]

Is it differ in DM to choose ticagrol ,prasogrol
May be in high sugar ?

[@sridharangopalakrishnan4131]

Dear doctor, thank you very much for the most valuable information for me. My doctor has continued to prescribe Brilinta (Ticagrelor) even after three years. Is that ok doctor?

[@TheICUChannel]

Sorry, This is a medical educational channel not a medical advice channel .

[@sweetysingh2710]

sir please make video on dose of inotrops in infusion .

[@TheICUChannel]

It’s already there on channel , please search in playlist

[@MostaqueAhmed-z9c]

What's about anticoagulant in stemi when transferring to pci capable Hospital

[@abumuhammedkhalid8023]

❤❤

[@drdineshjaluka]

Why switched back to clopidogrel after 1 yr. Plz reply

[@srikanthks2841]

Dear sir is there any caution that needs to be considered in case the patient has or had anuerism. Will the choice of drug change? Is there any correlation that we need to consider based on their past history of stroke or known aneurism

[@RakeshValvi-n6h]

Sir request to u , write short note and ppt regarding acs, nstmi stmi managment

[@TheICUChannel]

th-cam.com/video/fKnu7i8Fnkc/w-d-xo.htmlsi=QmkJMSHBW_5ycP-T

[@FitHameshaByDrSaurabh]

❤

[@medicoo9832]

Sir the plane was going😅😂😂

[@TheICUChannel]

@@medicoo9832 ha ha

[@drajaykumardalavi3289]

sir can we use,atovastatin*clopigodril+asprin along with ticagoril, inpatient who got stent,

[@TheICUChannel]

Why triple antiplatelets?

[@drkounsar]

hi, first -should we stop any dose of clexane before going for pci? second - should we continue to give clexane in therapeutic dose post pci?thanks

[@RNTEagle1]

Actually depends on Personal Practice of Cardiologist. Where there was Significant Thrombus Burden They Continue For 1 or 2 days Then discontinue.

[@neerajnarang5872]

Jain saab kaun se hospital mein hein

[@TheICUChannel]

Apollo Hospital , Indore

[@samuelnoklang7027]

Can we use Ticagrelor in CAD patients with h/o Asthma or COPD?

[@TheICUChannel]

Depends on his/her symptoms, if not aggravating , then can use based on the necessity

[@PallavDesai7396]

SIR what is the concept behind Clopidogrel 75g BD ?

[@TheICUChannel]

I didn’t understood this question, can u elaborate?

[@sijosebastian9544]

Which antiplatelet agent would you use in a patient with Idiopathic Thrombocytopenia with a baseline Platelet level below 50k Sir?
How do we differentiate and mitigate the risk of Bleeding vs Thrombosis in such a patient?
Regards

[@RAJYASREE-x6z]

Sir / maddam. Clopidogrel. Is such the help to all thus the care of. Wbc iis less then got the infection.
Prasugrel. Is such the help to the. Wbc the help to all. That the wbc low then the care is diredore of that ++++
Ticagrelor. Is such the help to all where the wbc is less but the care is giving to the care of this the helping them the care of firefior of this the help to all thus help thanks sir / maddam.
Another thing is that all the above is same bu the mode of action is same but the help to all is that the wbc then the care of number of stroke ware as well thus the helping them as well.
Thus thanks sir / maddam