Erythroblastosis fetalis | Rh Incompatibility
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- เผยแพร่เมื่อ 10 ก.ย. 2024
- #hussainbiology #apbiology #csirnet
ABO Antigens : • Biochemistry of ABO An...
In this video we will be discussing about the Rh disease also termed as Erythroblastosis fetalis.
Hemolytic disease of the newborn, also known as hemolytic disease of the fetus and newborn, HDN, HDFN, or erythroblastosis fetalis,is an alloimmune condition that develops in a peripartum fetus, when the IgG molecules (one of the five main types of antibodies) produced by the mother pass through the placenta. Among these antibodies are some which attack antigens on the R.B.Cs in the fetal circulation, breaking down and destroying the cells (hemolysis). The fetus can develop reticulocytosis and anemia. This fetal disease ranges from mild to very severe, and fetal death from heart failure (hydrops fetalis) can occur. When the disease is moderate or severe, many erythroblasts (immature red blood cells) are present in the fetal blood, and so these forms of the disease can be called erythroblastosis fetalis (or erythroblastosis foetalis).
Antibodies are produced when the body is exposed to an antigen foreign to the make-up of the body. If a mother is exposed to a foreign antigen and produces IgG (as opposed to IgM which does not cross the placenta), the IgG will target the antigen, if present in the fetus, and may affect it in utero and persist after delivery. The three most common models in which a woman becomes sensitized toward (i.e., produces IgG antibodies against) a particular antigen are hemorrhage, blood transfusion, and ABO incompatibility.
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The video, drawings and overall explanations are great. Due to a slight pronunciation defect, it's sometimes difficult to understand every single word. It would've been helpful having subtitles enabled. Regardless of this, thanks for your dedication.
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Wonderfully explained. But i felt that the pronounciation of the English words could have been better. Explained it in a very interesting way. 👏🏽
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sir if we transfuse rh + blood to a rh negative person the person get ill
so in this case also the rh + blood ( from baby) is somehow entering the person who is rh - (mother ) why is it not affecting the mother at first
He is a kashmiri teacher!👍
Yes Dear...
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I was confused during the whole video, I didn’t understand the main points. I need help
happy to help.. Proceed
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.Doc
I have a doubt sir_ The blood coming in the baby is from mother's body through umblical cord, then the blood of baby and mother is different then how can bay survive?👈👈👈👈👈👈👈👈👈👈👈👈👈👈👈👈👈👈👈👈👈👈👈
Blood doesnt mix up,,,,,
We see through the blood vessels in the umbilical cord, the fetus receives all the necessary nutrition, oxygen, and life support from the mother through the placenta.
Well going 🙌
Very good. But I want m.sc.level class for net examination. So be more detail and I can cover net jrf examination. 😀😊
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4:11 what if the child doesnt have d antigen? Will it still get affected??
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Thank u a lot sir
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Amazing video 👌
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Well explained🙂
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What happened for vice versa condition ? Mom is Rh + and fetus is Rh - ?
In that case problem would persist only if babies had fully fledged Immume system but they haven't...that is why thr Rh+ Mother and Rh- baby doesn't prove to be fatal.
I see, thank you for your response. I appriciate it
Why IgG can cross plaxenta?
It is great to answer your followers questions it’s very helpful for others
Ihsan Bangash bcz igG molecules weight is very low so it cross the placenta
Really very nice 😊😊😊
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Very helpful! 😃
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Thank you sir
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sir confusion
o group has H antigen Or no antigen plzz reyy
Yes , O Group has H Antigen....
Watch this vidoe and clear your concept
th-cam.com/video/Kf4eb-CBF-s/w-d-xo.html
Sir, upload( mns grouping) system and its mechanism in detail.
What combination of Father and mother for Rh + or negative is dangerous
Best explanation ....nw I understand it well
Sir, one question . can baby's antigen enter into mother's body during 2nd pregnancy like in 1st pregnancy and cause harm to mother's also.
Sir, why antiD antibodies are administered to the mother, by prevents the formation of anti D antibody in the mother blood.. please explain it! "Both are same "
Same question
Thanks for the explanation! Liked this video
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Sir, the first baby can also suffer from erythroblastosis foetalis as IgG can also enter into the neonate through the mother's milk?? 🤔🤔
Wonderful
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nice 👌👍
Great concept 🙂👍
thanks
If mother is O+ve Father is O-ve
Is there any problem in pregnancy???
no
sprrrb.......thnx lot
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