Partition coefficients

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  • เผยแพร่เมื่อ 21 ส.ค. 2024

ความคิดเห็น • 41

  • @mairaa786
    @mairaa786 9 ปีที่แล้ว +23

    This video is the only video which has actually helped me understand both coefficients P and D, thank you so much!

    • @Noone-kz5yq
      @Noone-kz5yq 6 หลายเดือนก่อน

      where are you now?

  • @mck421
    @mck421 6 หลายเดือนก่อน +1

    This was incredibly helpful. Thank you for making this video!

    • @GrahamLappin
      @GrahamLappin  6 หลายเดือนก่อน

      Very pleased it helped.

  • @Ace4897
    @Ace4897 3 ปีที่แล้ว +1

    I pay $18,600 a semester at the University of Technology of Sydney's Graduate School of Health and instead of bothering to teach us themselves, they send us a link to your video. Hope you're getting a kickback mate

    • @GrahamLappin
      @GrahamLappin  3 ปีที่แล้ว +3

      No kickbacks I'm afraid. Actually I'm not in it for the money, I'm only too pleased to spread the educational word as best I can.

  • @vitokonte
    @vitokonte 9 ปีที่แล้ว +12

    VERY useful and clear explanation. Excellent for my pharmacy revision! More of these videos would be awesome!

    • @GrahamLappin
      @GrahamLappin  8 ปีที่แล้ว

      Let me know what subjects might be useful and I'll see if I can make some more.

  • @sarahhe.5455
    @sarahhe.5455 3 ปีที่แล้ว

    This is the best explanation of the concept!!!! Life saver

  • @tbviaemail
    @tbviaemail 5 ปีที่แล้ว

    I learned a lot watching and taking notes from your video. I think you found your "sweet spot" for your purpose in life... by helping others achieve chemistry!!!

  • @johnblacksuperchemist2556
    @johnblacksuperchemist2556 2 ปีที่แล้ว

    EXCELLENT VIDEO.............THANK YOU!!!!!!!!!!! I finally understand Kc and Kd. Except one thing. Your video was great. I am going to outline this video and put it in my notes it was that good

  • @futuredrkiran
    @futuredrkiran 7 ปีที่แล้ว

    Brilliant, very clear in explaining Log D and LogP!!!! Thank you sir.

  • @ZHEER
    @ZHEER 7 ปีที่แล้ว

    Thank you very much, sir! My lecturer can't explain anything well. I'm glad I was able to find this video.

  • @n.sue-ann5527
    @n.sue-ann5527 5 ปีที่แล้ว

    Really learnt lot from watching this. Please keep them coming.

  • @ahmadfares5243
    @ahmadfares5243 ปีที่แล้ว

    Very good explanation ❤انت ممتاز

  • @nakulakolkar4701
    @nakulakolkar4701 7 ปีที่แล้ว

    excellent sir, it was a visualization of mathematics in true sense

  • @willmcconnell6008
    @willmcconnell6008 3 ปีที่แล้ว

    Super helpful explanations!

  • @jaskaur7885
    @jaskaur7885 8 ปีที่แล้ว

    Thank you so much, I'm a pharmacy student and this has really helped me! Please make more videos! :)

  • @crashjohnny_
    @crashjohnny_ 8 ปีที่แล้ว

    Awesome video! Thank you so much. You explained it in a very easy way to understand, I really would like to see more videos of yours!

    • @Noone-kz5yq
      @Noone-kz5yq 6 หลายเดือนก่อน

      where are you now?

  • @gold0member
    @gold0member 6 ปีที่แล้ว

    Thanks a lot. You have made it so simple ! Amazing.

  • @erikavillacis8149
    @erikavillacis8149 6 ปีที่แล้ว

    Thank you so much. You really solve my life.

  • @saumilshah3515
    @saumilshah3515 4 ปีที่แล้ว

    You are awesome, thankyou for your contribution.

  • @WheelofFortune731
    @WheelofFortune731 5 ปีที่แล้ว

    Clear explanation! Thank you very much

  • @hayaali8127
    @hayaali8127 8 ปีที่แล้ว

    Excellent lecture ! Thank you so much !!

  • @sderese
    @sderese 6 ปีที่แล้ว

    What a nice lecture

  • @fatmahmansi4291
    @fatmahmansi4291 5 ปีที่แล้ว

    this is really helpful. thank you.

  • @milesmaxwell9599
    @milesmaxwell9599 8 ปีที่แล้ว

    I finally understand this thank you!!

  • @fitsumgirmawi3678
    @fitsumgirmawi3678 4 ปีที่แล้ว

    Thank you, very helpful.

  • @chappapraveen8698
    @chappapraveen8698 5 ปีที่แล้ว

    Thanks a lot

  • @debrahisaiah7025
    @debrahisaiah7025 8 ปีที่แล้ว

    wow. good lecture

  • @khan_farhan1
    @khan_farhan1 5 ปีที่แล้ว

    Helped a lot

  • @johnblacksuperchemist2556
    @johnblacksuperchemist2556 2 ปีที่แล้ว

    QUESTION........FIRST ...am i right in assuming Kc=Kp=Kpc are all the same thing (synonyms)??????? Why does Kp / logKp not take in to account what the solute is????? I did a problem where the Kpc for ether/water was 4. I can not remember what the solute was but let us say it was acetic acid. Is the Kpc for ether/water... where the solute is pentanoic acid ....going to ALSO be 4 ????? Cause acetic acid is miscible in water and pentanoic is not so i would think the Kpc would be different since pentanoic acid is less soluble in water. But the equation does not seem to take that in to account???????

  • @haythamkhalil4675
    @haythamkhalil4675 6 ปีที่แล้ว

    Thanks a lot , for this video

  • @jessethedr7925
    @jessethedr7925 7 ปีที่แล้ว

    excellent

  • @mejojo924
    @mejojo924 9 หลายเดือนก่อน

    HERO

  • @AshishKumar-hm4fo
    @AshishKumar-hm4fo 4 ปีที่แล้ว

    Is there any software or online web site where we can find these values for a particular compound.

    • @GrahamLappin
      @GrahamLappin  4 ปีที่แล้ว

      Log-P is often quoted for drugs but log-D requires values at different pH values and so I am not aware of any database giving those.

    • @AshishKumar-hm4fo
      @AshishKumar-hm4fo 4 ปีที่แล้ว

      @@GrahamLappin Does Log P value also changes with pH?

    • @GrahamLappin
      @GrahamLappin  4 ปีที่แล้ว +1

      @@AshishKumar-hm4fo As the video explains, Log-P refers to the octanol-water partition and so does not take pH into account. If the pH is accounted for, then it becomes Log-D If a Log-D value is given, the pH it's measured at should be quoted.
      Log-D for a given pH can be calculated from the Log-P and the pKa which is covered in the video from about 21 minutes. Many drugs have their Log-P and pKa listed (DrugBank website is a good source).