What is chirality and how did it get in my molecules? - Michael Evans

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  • เผยแพร่เมื่อ 5 ก.ย. 2024
  • Improve your understanding of molecular properties with this lesson on the fascinating property of chirality. Your hands are the secret to understanding the strange similarity between two molecules that look almost exactly alike, but are not perfect mirror images.
    Lesson by Michael Evans, animation by Safwat Saleem and Qa'ed Tung.

ความคิดเห็น • 167

  • @Volidee
    @Volidee 11 ปีที่แล้ว +219

    Oh my god, this is my organic chemistry teacher at UIUC! I can't wait to tell him I saw this video.

    • @enzoereddia2044
      @enzoereddia2044 4 ปีที่แล้ว +12

      tell him i want ted back

    • @samuraijosh1595
      @samuraijosh1595 3 ปีที่แล้ว +4

      Yo, so how did the convo go that day..?

    • @samuraijosh1595
      @samuraijosh1595 3 ปีที่แล้ว +1

      @@oliverdayton3827 Damn. It took me 15 minutes too. But it didn't work!!

    • @blackcat5771
      @blackcat5771 3 ปีที่แล้ว +1

      @@samuraijosh1595 lmao i wanna know too

    • @tonymaurice4157
      @tonymaurice4157 2 ปีที่แล้ว

      RNA World experiments involve a long series of Highly orchestrated steps which include purifying desired products, removing unwanted byproducts, changing physical and chemical conditions, adding unrealistically high concentrations of assisting substances and other interventions to ensure that the target molecules are achieved. It's highly manipulated controlled chemistry that has no relevance to the Early Earth!
      Proto-cells are not life-like, the requisite ribosomes mRNA, enzymes and reagents were purchased from a chemical company or extracted from a pre-existing living system. Then added to the medium and permitted to diffuse into the manmade plastic capsules.
      The center for chemical evolution is not making progress!
      The experimental setups are permeated with clever manipulations tweaking pH and temperature as needed along the way using UV radiation at the right times and durations to remove problematic side-products, highly purified chemicals, it bears no relevance to pre-biotic conditions!

  • @jesusfreak7389
    @jesusfreak7389 12 ปีที่แล้ว +45

    chirality it one of these things that make organic chemistry so hard for me, thanks for the video, it helps a lot especially right before my test!

    • @tonymaurice4157
      @tonymaurice4157 2 ปีที่แล้ว

      RNA World experiments involve a long series of Highly orchestrated steps which include purifying desired products, removing unwanted byproducts, changing physical and chemical conditions, adding unrealistically high concentrations of assisting substances and other interventions to ensure that the target molecules are achieved. It's highly manipulated controlled chemistry that has no relevance to the Early Earth!
      Proto-cells are not life-like, the requisite ribosomes mRNA, enzymes and reagents were purchased from a chemical company or extracted from a pre-existing living system. Then added to the medium and permitted to diffuse into the manmade plastic capsules.
      The center for chemical evolution is not making progress!
      The experimental setups are permeated with clever manipulations tweaking pH and temperature as needed along the way using UV radiation at the right times and durations to remove problematic side-products, highly purified chemicals, it bears no relevance to pre-biotic conditions!

  • @NoriMori1992
    @NoriMori1992 7 ปีที่แล้ว +88

    I read once that there's some work of fiction where a man's chirality gets flipped, and at first it's just amusing because his dominant hand switched, but then it turns out he can't digest food because his body molecules have the wrong chirality to interact with the food molecules correctly…

    • @ThisNameIsG
      @ThisNameIsG 7 ปีที่แล้ว +5

      do you remember what it's called?

    • @metacylinder
      @metacylinder 6 ปีที่แล้ว +11

      NoriMori Technical Error by Arthur C Clarke?

    • @musikali1
      @musikali1 4 ปีที่แล้ว +5

      I would advise this man to try some OTC nasal spray ;-)

    • @JET7C0
      @JET7C0 2 ปีที่แล้ว +1

      @@metacylinder That's definitely the story

    • @MasonJuarez
      @MasonJuarez ปีที่แล้ว

      It's not a big plot point or anything but in "To be taught, if fortunate" they're astronaut exploring a few planets and they eventually notice different planets have organisms that digest different chirality molecules, even one planet where organisms can digest both .

  • @mariaealvarez
    @mariaealvarez 11 ปีที่แล้ว +21

    good video! Although I found disturbing al the "funny comment bubbles"... they didn't let me concentrate on what was really important, what you were trying to teach.

  • @arthur78
    @arthur78 12 ปีที่แล้ว +20

    Strange coincidence: I learned about chirality today for the first time while watching episode 2 (or 3) of Breaking Bad, and then this video pops up... always amuses me when I see or learn about something for the first time in my life, only to have cross my path again seemingly by pure chance on the same day. I don't believe in any significance to coincidences, but one can't shake the eerie feeling when such things happen few times in a row.

    • @meh-ws7wp
      @meh-ws7wp 6 ปีที่แล้ว +1

      Arthur78 same happened with me.

    • @ge2719
      @ge2719 4 ปีที่แล้ว

      Where did you watch it and did you have Alexa or Google listening to you watch it?

    • @AdityaKumar-ez4ey
      @AdityaKumar-ez4ey 4 ปีที่แล้ว +1

      This is called the Baader Meinhof Phenomenon

    • @imaadshabir5713
      @imaadshabir5713 6 หลายเดือนก่อน

      It's called yt algorithm.... Ur data goes to all these sites

  • @aaa123181
    @aaa123181 8 ปีที่แล้ว +21

    outstanding animation and nice presentation............thank you

  • @TheYipedo
    @TheYipedo 12 ปีที่แล้ว +5

    That awesome moment when you see this video in your feed and you just learned about chirality a few hours ago in organic chem class.

    • @camazotzz
      @camazotzz 4 ปีที่แล้ว +3

      your phone hears all and sees all

  • @ladywhyasker
    @ladywhyasker 12 ปีที่แล้ว +6

    The animation for this lesson is just brilliant!

  • @sk-un6vw
    @sk-un6vw 2 ปีที่แล้ว +11

    Walter White brought me here

  • @niki6399
    @niki6399 6 ปีที่แล้ว +6

    this video explained something that i was incredibly confused about in a perfect manner. thank you so much

  • @silencedidgood
    @silencedidgood 12 ปีที่แล้ว +3

    Wow. Excellent. Spatial Geometry combined with History and Chemistry. So seldom do I see such synthesis!

  • @CLEANDrumCovers
    @CLEANDrumCovers 11 ปีที่แล้ว +31

    Wrong example used at 1:35 . The molecules aren't mirror images of one another, they are stereoisomers, but aren't enantiomers (as hands are), they are diastereomers (as hands aren't).

    • @vetteluvnh
      @vetteluvnh 7 ปีที่แล้ว +13

      Thanks for the clarification/correction, Daniel. Looks like I have 3 new words to learn!

    • @islandbuoy4
      @islandbuoy4 6 ปีที่แล้ว +2

      yes you can see the F and H swap positions, is this why you define them the way you do?
      4 years ago
      still out there

    • @kavishshah8282
      @kavishshah8282 6 ปีที่แล้ว

      they are mirror images of one antother. br(bromine) is out of the plane and if we place a mirror b/w them, br will remain out of the plane but f and h will chnage positions... plz reply if this analogy is wrong.

    • @edibingbing1
      @edibingbing1 6 ปีที่แล้ว

      There are two main form of stereoisomerism: cis-trans and enantiomers. Mirror image can display enantiomerism when they are non-superimposable (meaning that when the mirror image are placed on top of one another, they cannot give the same molecule). I thought that diastereomers are any stereoisomers tat is not enantiomers. Correct me if i am wrong... we are all here to learn :)

    • @taktsing4969
      @taktsing4969 6 ปีที่แล้ว

      They are mirror image. Not sure if Ted edited the footage.

  • @LiborTinka
    @LiborTinka 6 ปีที่แล้ว +4

    Interesting. I always though the bonded atoms around the carbon can freely rotate but they merely vibrate. Now I finally understand the chirality...

  • @stargazeronesixseven
    @stargazeronesixseven 4 ปีที่แล้ว

    Top Notch Tutorial on Chirality! Thank You So Much for Sharing! ♥️🌷🕯

  • @kranked354
    @kranked354 12 ปีที่แล้ว +1

    A five minute one at that. Most science teachers take about 3 lessons/lectures to teach the concept.

  • @duoc-moi
    @duoc-moi 10 ปีที่แล้ว +12

    I dont understand why at 1:35 you got asymmetric molecules, but at 3:10 you got symmetric molecules? Is there a mistake?

    • @moontiger6393
      @moontiger6393 9 ปีที่แล้ว

      in that one its a mirror image

    • @dkhl65
      @dkhl65 7 ปีที่แล้ว +3

      At 3:10, they are not "symmetric". Outside the mirror, Br is sticking out of the screen (represented by solid triangle pointing to C) and Cl is sticking into the screen (represented by dashed triangle). The mirror one would be the opposite, with Br going in, Cl coming out.

    • @andrewbradford1794
      @andrewbradford1794 5 ปีที่แล้ว +1

      It is a mistake. You're right Mr. Random that Br should be sticking out of the screen, but in the 3D model they made, it's not. You can see this at 3:12 when the white dotted line passes barely in front of the "r" in "Br".
      Even if they had gotten that right, they should have also swapped the dashed/solid triangles in the mirror image.

  • @kikicwazy5
    @kikicwazy5 12 ปีที่แล้ว +2

    Just studied this in chem! Love it :3

  • @subhendugorai9715
    @subhendugorai9715 7 ปีที่แล้ว

    such a video I have seen it can not explain in word ..... thank you so much keep it up

  • @MyNameIssBob
    @MyNameIssBob 12 ปีที่แล้ว

    A TH-cam video just explained chirality better than my science teacher.

  • @elessal
    @elessal 4 ปีที่แล้ว +9

    Any porters here?

  • @jebc4652
    @jebc4652 5 ปีที่แล้ว

    It is certainly interesting, this issue of chirality.

  • @getthrough5251
    @getthrough5251 3 ปีที่แล้ว

    Beautifully explained

  • @DaRealFiberOptix
    @DaRealFiberOptix 12 ปีที่แล้ว

    fractals also explain our consciousness, you can apply the term fractal or resonance, ive been leaning toward resonance these days, seems to fit and concresce a little better(explains the same thing as fractal). I loved learning all about the patterns. It led me to Terence Mckenna and Alan Watts. who are easily some of the smartest minds to ever grace this planet. Alan watts talks a lot about neurological resonance, he was an utter genius.

  • @JoQuerSan
    @JoQuerSan 12 ปีที่แล้ว +1

    Symmetry and chirality are not the same, I think it means that since people like symmetry, we don't make objects that are (for example) bigger from one side than the other and then make the same object inverted so they look like mirrored images.
    Of course symmetric objects will look the same on the mirror, but chiral objects NEED the mirror to look the same, that's the thing.

  • @mikiclues3326
    @mikiclues3326 11 ปีที่แล้ว

    Thank you so much, I was so confused about what a left handed amino acid was

  • @NikitaSharma-bs4gg
    @NikitaSharma-bs4gg 11 ปีที่แล้ว

    what a video !!!!!!!!! i want to learn every subject in this manner only//////

  • @AppA
    @AppA 12 ปีที่แล้ว +1

    I felt like I got this and understood it completely, so afterwards I began re-watching this for no apparent reason until I remembered that I was really fucking baked.

  • @LimmingKenny
    @LimmingKenny 12 ปีที่แล้ว

    If you're interested in natural shapes and patterns of the universe, learn about fractals and how they can explain the structure of plants, lightning, entire planets, circulatory systems, and more

  • @blazerider6
    @blazerider6 12 ปีที่แล้ว +1

    I think you're asking the wrong question. Chiral molecules are simply two different ways of forming a molecule. It's usually based on the position of the atoms when they bond together. At no point did some event happen to "create" chirality.

  • @kinga2435
    @kinga2435 8 ปีที่แล้ว +2

    Thanks a lot :)

  • @NileshKumar81020
    @NileshKumar81020 3 ปีที่แล้ว

    Thank you

  • @onaireves15
    @onaireves15 12 ปีที่แล้ว +1

    more o chem!...i love it

  • @TheArchsage74
    @TheArchsage74 6 ปีที่แล้ว +27

    Is this gonna be on the murder?

    • @ij852
      @ij852 4 ปีที่แล้ว +1

      TheArchsage74 What. Yes I mean no maybe doesn’t hurt to know it right knowledge is power

  • @eatcarpet
    @eatcarpet 12 ปีที่แล้ว +5

    What Wiki says:
    "The origin of this homochirality in biology is the subject of much debate. Most scientists believe that Earth life's "choice" of chirality was purely random, and that if carbon-based life forms exist elsewhere in the universe, their chemistry could theoretically have opposite chirality. Circularly polarised radiation could have caused the selective destruction of one chirality of amino acids, leading to a selection bias which resulted in all life on Earth being homochiral."

  • @eatcarpet
    @eatcarpet 12 ปีที่แล้ว

    If there's a great concept then it should be able to be explained simply.

  • @YaSokeeYang
    @YaSokeeYang 12 ปีที่แล้ว

    1)He did not say it has been pointed out yet.
    2) He says it because there is a possibility something like that could be brought up LATER.

  • @unvergebeneid
    @unvergebeneid 12 ปีที่แล้ว

    Well, not being able to translate and rotate an object on its mirror image is the definition of chirality, yes. My point is that it does not make sense to say that people don't like chirality because they like symmetry since you can make everything axially symmetric if you mirror it. And people use this to a great extent as the fleurons I borrowed from Unicode show.

  • @md.yasinkhan984
    @md.yasinkhan984 3 ปีที่แล้ว

    Loved it

  • @hiro95959
    @hiro95959 12 ปีที่แล้ว

    awww i wanted it to explain more about it

  • @ciprianpopa1503
    @ciprianpopa1503 ปีที่แล้ว +1

    What Einstein has to do with chirality?

  • @lrpbpb
    @lrpbpb 12 ปีที่แล้ว

    But doesn't chirality depend on perpective? If you hold a pencil such that you hands are parallel and the tip points to your left palm, then the object is chiral. But if point the pencil prependicular to your eyes, then it isn't chiral...(to give an example)

  • @inbisatanwar9675
    @inbisatanwar9675 5 ปีที่แล้ว +2

    I love ted ed

  • @HienNguyenHMN
    @HienNguyenHMN 12 ปีที่แล้ว

    Personal experience: I'm right-handed and sometimes buy jackets with left-handed zippers. It's really frustrating to zip them up with the "wrong" hand.

  • @Bryce-Fisher
    @Bryce-Fisher 12 ปีที่แล้ว

    It doesn't seem that you are tired with these Debates, Considering that is the entire content of your channel :o

  • @sunflyification
    @sunflyification 12 ปีที่แล้ว

    I don't understand optical rotation. And what are other chiral objects besides hands and screws?

  • @shubham5792
    @shubham5792 5 ปีที่แล้ว

    At 1:48 the molecules are not mirror images of each other

  • @salaciousBastard
    @salaciousBastard 10 ปีที่แล้ว

    If you bond a chiral object to its mirror image along the axis of reflection, isn't the resulting object achiral?

  • @cajesnoli5493
    @cajesnoli5493 2 ปีที่แล้ว

    How chiral compounds interact?

  • @FubarLikeYou
    @FubarLikeYou 12 ปีที่แล้ว

    then the pencil isn't chiral at all, he went over that with the molecule when he said it didn't matter how he orientated the molecule, it wouldn't have all the parts in the same place from the same viewpoint. he could get a mirror image, but that isn't identical.

  • @CooperCarr
    @CooperCarr 12 ปีที่แล้ว +1

    Walter White explained this like a boss!

  • @eatcarpet
    @eatcarpet 12 ปีที่แล้ว

    How did all of this come about after the big bang? Did it "evolve"?

  • @Masterofallytps
    @Masterofallytps 12 ปีที่แล้ว +1

    Where did everyone go D:

  • @Anytus2007
    @Anytus2007 12 ปีที่แล้ว

    Yet, at a fundamental level this reflection-symmetry is broken. The Weak Force (one of the 4 fundamental forces) explicitly breaks this symmetry (know as parity).

  • @xiocron
    @xiocron 12 ปีที่แล้ว

    Chirality deals with objects in three dimensions, not just two.

  • @mkcobain
    @mkcobain ปีที่แล้ว

    those two molecules are not mirror images of each other

  • @masterineverything
    @masterineverything 12 ปีที่แล้ว

    Non orient able spaces can turn left

  • @jebc4652
    @jebc4652 5 ปีที่แล้ว

    How do the cicadas make so much noise?

  • @eatcarpet
    @eatcarpet 12 ปีที่แล้ว

    I was talking about HOW THIS CHIRALITY OCCURRED.

  • @immurlis13
    @immurlis13 ปีที่แล้ว +1

    Mit University 💖💖 I'm in

  • @suwa-turibto7181
    @suwa-turibto7181 5 ปีที่แล้ว

    ちょうど光学異性体の乳酸について勉強していたのでこの動画をみつけられて良かった

  • @333666666
    @333666666 12 ปีที่แล้ว

    "Major" and "minor" in music is chiral, too.

  • @Eyeapetus33
    @Eyeapetus33 11 ปีที่แล้ว

    The evidence that homochirality could occur through natural processes in life/for the creation of life is something we can calculate using mathematical probabilities. The probability that natural processes could produce this feature is 0%.

  • @orions7595
    @orions7595 7 ปีที่แล้ว

    BUT, if I can put my palms together, everything lines up, its a mirror, and since its all lined up perfectly, why isnt it superimposable? D:

    • @quantummechanics7140
      @quantummechanics7140 7 ปีที่แล้ว +4

      Remember your hands aren't 2D. Place your left hand palm down. If you line the fingers of your right hand up with your left your right hand will be palm up - not the same. They are mirror images but not superimposable.

  • @mbfjeld
    @mbfjeld 12 ปีที่แล้ว

    congratulations! :D

  • @RealCottonCandyKid
    @RealCottonCandyKid 12 ปีที่แล้ว

    Ok, and now I only need to know why it appears to be that there are only left-handed neutrino's...

  • @robertman
    @robertman 12 ปีที่แล้ว

    Firstly, an account of billions of years of cosmic happenings is not an idea, it is a history. Secondly, powerful ideas and theories often escape simple explanation ( see v=wMFPe-DwULM ). If you really want to know the answer rather then make empty objections you could read a "Bang!: The Complete History of the Universe" or a similar work, or try the wikipedia page on the "chronology of the universe".

  • @blazerider6
    @blazerider6 12 ปีที่แล้ว

    Yeah but that's chirality in organic molecules, not chirality in general. You didn't specify and i figured you meant in general because you said "after the big bang". Like i said your asking the wrong question. What I'm guessing you want to know is why life on earth only uses one out of the two. Which you answered yourself.
    Only thing I would add is that the random choice would be supported by evolution because its easier to form macro molecules if all of the parts are the same.

  • @thecrypticletters
    @thecrypticletters 6 ปีที่แล้ว

    can u just give the topic detail completely by explaining Evey thing every point related to a particular point

  • @WKSchwenke
    @WKSchwenke 3 ปีที่แล้ว +1

    And creating a cell from randomness (evolution) is impossible when chirality of the molecules is involved

  • @PanicRamsay
    @PanicRamsay 4 ปีที่แล้ว +1

    Hideo Kojima games always teach me new words.

  • @matheusmartins1123
    @matheusmartins1123 2 ปีที่แล้ว

    Mais alguém fazendo prova do sesi?

  • @25402702
    @25402702 12 ปีที่แล้ว +4

    Who else read "chirality" as "charity"...?

  • @alexmartinez3683
    @alexmartinez3683 2 ปีที่แล้ว +1

    BUT YOU ANC ROTATE YOUR HAND AND THEN THEY ARE SUPERIMPOSABLE

    • @DFEUERMAN
      @DFEUERMAN 2 ปีที่แล้ว

      If you rotate then the back of your hand and palm face you. I think achiral would be if the hand had palms on both sides.

  • @BobxLovesxMuffins
    @BobxLovesxMuffins 12 ปีที่แล้ว

    you are very smart :D

  • @xXgioXx15
    @xXgioXx15 12 ปีที่แล้ว

    the clock at the star is at 9 11 o.o

  • @joeylantis22
    @joeylantis22 12 ปีที่แล้ว +1

    I hate it when people say that God didn't create man, do I look like a freaking mokey??? So stupid!

  • @cordellftw
    @cordellftw 12 ปีที่แล้ว

    this tough me nothing im sorry. it basically summed up that molecules are just mirrored

  • @RedCartographerGames
    @RedCartographerGames 12 ปีที่แล้ว

    That animation was actually rather distracting with all of the dialogue boxes, I ended up reading those and not really paying attention. *sigh*

  • @valentina399
    @valentina399 4 ปีที่แล้ว

    K I know u r here for learning some chemistry but I can't be the only one who remembers skins because of the intro right?

  • @SirDan22
    @SirDan22 12 ปีที่แล้ว +1

    i learned this from breaking bad ! :)

  • @Ilovelimabeans
    @Ilovelimabeans 5 หลายเดือนก่อน

    Didn't explain How it got there!!!

  • @McLovinlt
    @McLovinlt 12 ปีที่แล้ว

    nuh uh, magical sky d00d

  • @AKGaming-oj8hk
    @AKGaming-oj8hk 6 ปีที่แล้ว +3

    I Know you are here yong.

  • @unvergebeneid
    @unvergebeneid 12 ปีที่แล้ว

    People like symmetry, so there aren't many chiral objects? ❧❧❧ Didn't make sense to me! ☙☙☙

  • @jupjup9737
    @jupjup9737 3 ปีที่แล้ว

    This is complex

  • @eric632
    @eric632 12 ปีที่แล้ว

    I'm so confused...

  • @thecrippledpancake9455
    @thecrippledpancake9455 2 ปีที่แล้ว

    3:16

  • @morganthem
    @morganthem 10 ปีที่แล้ว

    Written language is chiral.

    • @morganthem
      @morganthem 10 ปีที่แล้ว +1

      except MAYBE for, loosely, palindromes :)

  • @Sebkarp0
    @Sebkarp0 7 ปีที่แล้ว

    When you stick out your hands like that the palms are flipped the other way xD

  • @5tonyvvvv
    @5tonyvvvv 5 ปีที่แล้ว +2

    Intelligence is always required to generate genetic information!
    The RNA world has failed!

    • @carmen_13
      @carmen_13 2 ปีที่แล้ว

      Coping?

    • @tonymaurice4157
      @tonymaurice4157 2 ปีที่แล้ว

      @@carmen_13 amino acids come in left and right-handed but life only uses the left-handed variety, and they have to be sequenced in a specific correct order in order to have a functional protein.. purely natural chemical processes have never achieved this.
      And RNA World experiments involve a long series of Highly orchestrated steps which include purifying desired products, removing unwanted byproducts, changing physical and chemical conditions, adding unrealistically high concentrations of assisting substances and other interventions to ensure that the target molecules are achieved. It's highly manipulated controlled chemistry that has no relevance to the Early Earth!
      Proto-cells are not life-like, the requisite ribosomes mRNA, enzymes and reagents were purchased from a chemical company or extracted from a pre-existing living system. Then added to the medium and permitted to diffuse into the manmade capsules.
      The center for chemical evolution is not making progress!
      The experimental setups are permeated with clever manipulations tweaking pH and temperature as needed along the way using UV radiation at the right times and durations to remove problematic side-products, highly purified chemicals, it bears no relevance to pre-biotic conditions!

  • @DaRealFiberOptix
    @DaRealFiberOptix 12 ปีที่แล้ว

    the pattern of reflection is one of the most obvious patterns of the universe, like the spiral or the wave. everything is yin and yang.. these slow westerners.. wait i am 1

  • @Scarr420
    @Scarr420 12 ปีที่แล้ว

    Amen! ;)

  • @SenteintBeings
    @SenteintBeings 12 ปีที่แล้ว

    Learned this from Breaking Bad!

  • @cjtaormina5610
    @cjtaormina5610 11 ปีที่แล้ว

    ladies and gentlemen, this is how you start a comment war.

  • @enzoereddia2044
    @enzoereddia2044 4 ปีที่แล้ว

    where is ted who are these random people who have hacked ted's channel?!?.........help

  • @Hugo-lm7ed
    @Hugo-lm7ed 5 ปีที่แล้ว

    I thought thumb was a finger

  • @harshav2
    @harshav2 3 ปีที่แล้ว

    Hi

  • @eatcarpet
    @eatcarpet 12 ปีที่แล้ว

    What the hell are you talking about? I said nothing about the explanation of the big bang. Please read my post properly.

  • @kcinknowsbest
    @kcinknowsbest 12 ปีที่แล้ว

    Nope, I don't get it.

  • @AyJay2303
    @AyJay2303 12 ปีที่แล้ว +1

    Walter white = Heisenberg