Oxygen Content And Oxygen Delivery - Concepts and Equations Explained Clearly
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- เผยแพร่เมื่อ 8 ก.พ. 2025
- Oxygen content and oxygen delivery are two concepts that are critical to understand how the body functions and what happens when that function breaks down. In this video we explain these processes in a clear and full manner with clinical examples included.
Aerobic metabolism goes through the Kreb's Cycle and ends in Oxidative Phosphorylation, which creates the bulk of the body's energy in the form of ATP. Oxygen is critical to this pathway and without it cells are forced to primarily utilize anaerobic metabolism creating lactate and very few ATP. This is why oxygen content and oxygen delivery are so critical to understand.
Oxygen content is the amount of oxygen contained in the arteries. There are two general components of this being the oxygen attached to the hemoglobin molecules in the red blood cells and the amount of oxygen dissolved in the arteries. As such, the equation for oxygen content includes hemoglobin, oxygen saturation of the hemoglobin, and the partial pressure of arterial oxygen using two constants to convert the units to milliliters of oxygen per deciliter of blood. We dive into this equation and explain it in a way that makes sense, including examples using normal numbers, anemia, hypoxemia, and hyperoxia.
Oxygen delivery is the amount of oxygen delivered through the blood stream to the tissues. This is based on the cardiac output and the oxygen content with cardiac output being a result of stroke volume and heart rate. We again decipher this equation in a way that makes sense using the concepts behind it. We provide examples of the calculation.
Lastly, we go through different parts of oxygen content and delivery that can go awry clinically and how to best intervene.
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Excellent explanation 🎉🎉
Thank you very much! We appreciate the kind words and for checking out the video!
Perfect timing. Dad has C.O.P.D coming home to roost. Thanks.
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I was about to comment that too, so putting it here. I like both. Avatar is more noticable this way. New mentions content as well so that's better for new to the channel.
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Good afternoon, and thank you for your lectures. I work in the field of chronic wound management, utilizing various modalities to address hypoxic conditions in wound environments and improve vascular perfusion. Over 90% of our patient population consists of individuals with diabetes, suffering from diabetic foot ulcers (DFUs) or venous leg ulcers (VLUs). I would be interested in discussing, possibly in a lecture or another form of communication, the pathophysiological mechanisms by which diabetes leads to vascular damage. This damage results in impaired blood flow, inadequate nutrient delivery, and reduced oxygen supply to wound sites, ultimately hindering the wound healing process.
Amazing
Appreciate the kind words! Thanks for checking out the video!
Possible afferent transparent vessels supporting csf
There's not a ton of hemoglobin in 1 rbc , there's 4 quadrants of hemoglobin or 4 ends each end bond with 1 oxygen molecule having 4 oxygen molecules in line with the 4 quadrants of the body or having the identical map of the circulatory system, the hemoglobin is organized chromosomes. The oxygen(less carbon) saturation in bloodstream specifically the plasma depends on the amount of oxygen in the rbc's or the volume of rbc's in relation to the volume of oxygen in plasma, the amount of oxygen in plasma is regulated by the bronchials. Rbc's repell rbc's and collect oxygen, oxygen is stripped from the rbc's through osmotic pressure, mucus covers the alveoli to prevent diffusion of oxygen. If the 2 oxygen molecules are stripped from the carbon molecule bond? Possible the bond to the hemoglobin could be held together by the 1 carbon molecule but that would show 8 oxygen molecules in 1 rbc considering the o2 is broken up releasing the 2 oxygen molecules from 1 carbon molecule, o2 broken up leaves 4 carbon molecules to 8 oxygen molecules, all considering the amount of o2 in the volume of rbc's in the efferent path of the system regulated by the r.atrium considering it's the final destination in circulation to the lungs and the saturation level of the efferent path with the volume of serem fed into lungs. What is dissolved oxygen or would that mean oxygen without a covalent or ionic bond?
Good afternoon, and thank you for your lectures. I work in the field of chronic wound management, utilizing various modalities to address hypoxic conditions in wound environments and improve vascular perfusion. Over 90% of our patient population consists of individuals with diabetes, suffering from diabetic foot ulcers (DFUs) or venous leg ulcers (VLUs). I would be interested in discussing, possibly in a lecture or another form of communication, the pathophysiological mechanisms by which diabetes leads to vascular damage. This damage results in impaired blood flow, inadequate nutrient delivery, and reduced oxygen supply to wound sites, ultimately hindering the wound healing process.