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Unraveling Cannabinoid Hyperemesis Syndrome with Ethan Russo, MD
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- เผยแพร่เมื่อ 19 ส.ค. 2024
- Dr. Ethan Russo is a board-certified neurologist, psychopharmacologist, and Founder/CEO of CReDO Science. He is an internationally recognized authority on cannabis medicine. He has authored/edited seven books and has published more than 60 peer-reviewed articles. He also holds director/advisor positions with several cannabis therapeutics companies, and he was instrumental in developing Sativex® for pain and MS, and Epidiolex® for intractable epilepsy while at GW Pharmaceuticals.
At CannMed 24, Ethan will present “Cannabinoid Hyperemesis Syndrome (CHS): Unraveling the Gordian Knot”. CHS is an enigmatic condition where some chronic, heavy users of THC develop a cyclic pattern of vomiting and nausea that is only relieved by hot bathing and topical capsaicin. Ethan and his coinvestigators surveyed more than 500 cannabis users, including 205 diagnosed CHS patients, and investigated genetic mutations in 28 CHS patients and 12 controls to identify behaviors and genetic markers that could indicate CHS risk.
During our conversation, we discuss:
What is CHS and who does it affect
Why cases of CHS appear to be on the rise
Possible genetic markers that could indicate CHS susceptibility
Steps cannabis users can take to prevent developing CHS
Why some people in the cannabis community don’t believe CHS is a real thing
and more
Thanks to This Episode’s Sponsor: Cannabis Nurses Network
Established in 2015, the Cannabis Nurses Network™ is a professional nursing and professional development organization for nurses around the globe. By educating nurses on the science behind the plant and providing a global nursing network, nurses are supported and empowered to implement their knowledge within their community.
Learn more at cannabisnursesnetwork.com
Additional Resources
what-is-chs.com
ethanrusso.org
CReDO-science.com
Cannabinoid Hyperemesis Syndrome Survey and Genomic Investigation - pubmed.ncbi.nl...
Unraveling the Mystery of Cannabinoid Hyperemesis Syndrome - • Unraveling the Mystery... 2019 Panel
Register for CannMed 24 - cvent.me/1mGLAq
What Makes CannMed Unique and Why You Don’t Want to Miss It - medicinalgenom...
Review the Podcast! - podcasts.apple...
CannMed Archive - cannmedevents....
I have CHS and thank you so much for talking about it.
I had chs and I did not know I had it. I was smoking weed for 30 years. My chs came about 3 years ago. The first thing that happened was I was smoking a spliff, and halfway through smoking the spliff, I vomited and didn't understand why, so I continued to smoke. 3 months before this happened. I split from my wife and children, so I was already in a bad state of depression, not sleeping, and not eating too much. I continue to smoke after this first bout of vomiting. After this first bout of vomiting, i could not eat food, and my insomnia kicked in very badly. Maybe I'm just eating two spoons of my dinner per day, and maybe 2 to 3 hours of sleep a night. But I continue to smoke. I worked through this whole period doing manual labour, and somehow my body was still functioning, and I felt strong even with lack of sleep and hardly eating food. I was functioning on Coca-Cola, Lucozade, and spliffs. 6 months later, I hit a brick wall, and my body started to shut down. I went from 17 and a half stone down to 12 stone in 6 months. I started getting hypnic jokes when trying to sleep. Tinnitus in the ears. Body shaking once I did fall to sleep when I woke up with tremors. Muscle spasms. Muscle stiffness. Muscle pain. Bone pain. Muscle spasms in my back . Found it hard to walk. Numbness down my legs. Vomiting and nausea.Waking up with numbness in my arms and hands. Muscle spasms in my throat every time I lie down to try to sleep. Constipation. Haemorrhoids, I could not urinate properly. The Muscle spasms in my throat when I try to lie down, causing my throat to close, and i could not breathe when I lie down. All this time, i was going to the doctor's and getting nothing back from the doctors. Only telling me to sleep sitting up. The muscle spasms in my throat got so bad that I could not smoke because my throat started to close when standing or sitting. This obviously stopped me from smoking. My anxiety and depression were so bad from missing my kids and all the symptoms from the chs and I was still not diagnosed. I felt like I was dying. I doing researching everywhere and came across CHS. I then took this to the doctor, and they diagnosed me with CHS. I continue to work through this whole period. Looking back, I do not know how I got through. But I think the continuous moving of the body was helping me somehow. I started to eat a little better and slowly slowly I started to put my weight back on. After 1 year when I was able to lie down without my throat going into spasms I started to sleep a little better slowly slowly. It's been 2 and a 1/2 years since stopping smoking. After 1 year, I was still in a very bad way, with many symptoms still remaining. Having hot baths with Epsom salts was helping me a great deal. Putting warm olive oil all over my muscles was also helping. Drinking bone broth also helped a lot. After 2 years, my haemorrhoids started to calm down. I was able to go to the toilet better. Both urinating and pooing. It's been 2 and 1/2 years, and I'm still having tinnitus in the ears and spasms in my back and back pain, but it's nothing like the spasms and back pain I had before. I'm still suffering a little bit with insomnia. And when I wake from sleep, my arms and hands still go numb. Numbness down outside of my right leg. The biggest help I have found was through cranial therapy. When I start to feel quite good, sometime I would try to drink alcohol and smoke cigarettes. Drinking alcohol and smoking cigarettes seems to bring back some symptoms. I tried to drink sometimes to test my body. But then I realised I could not drink. Same with smoking cigarettes. Some symptoms start to come back. I have come to the realisation that I can not drink alcohol or smoke cigarettes. And obviously cannot smoke cannabis for the rest of my life. Even standing next to someone who is smoking a spliff affects me. I was always a very fit and strong individual and felt invincible. But this whole experience has humbled me. Please look after yourself and your health mentally and physically. The one good thing I can see about CHS is there if you stop smoking weed and live a healthy life it can go away. As I said I still have some symptoms. But I feel like if I look after myself hopefully I pray to God that will my symptoms will eventually go away. Is it possible that there is damage done that cannot be repaired but I am very thankful and go forward with a positive mindframe. Is very good to see that there is information out there for people to find. It did not occur to me to go on TH-cam and type in chs back then. But even the videos on TH-cam here do not talk about half of my symptoms. I obviously took CHS maybe to the Brim. And maybe I'm very lucky. That is very good to see there is information out there and people are learning more and more everyday about CHS. If you feel you have CHS the beginner or CHS why you feel you have had it for a while please stop smoking now. Go and seek help. As I said the best thing that I found helped me was cranial therapy and God. God bless you all out there, peace 🙏
I had chs and I did not know I had it. I was smoking weed for 30 years. My chs came about 3 years ago. The first thing that happened was I was smoking a spliff, and halfway through smoking the spliff, I had very bad stomach pains and stomach cramps and I vomited and didn't understand why, so I continued to smoke. 3 months before this happened. I split from my wife and children, so I was already in a bad state of depression, not sleeping, and not eating too much. I continue to smoke after this first bout of vomiting. After this first bout of vomiting, i could not eat food, and my insomnia kicked in very badly. Maybe I'm just eating two spoons of my dinner per day, and maybe 2 to 3 hours of sleep a night. But I continue to smoke. I worked through this whole period doing manual labour, and somehow my body was still functioning, and I felt strong even with lack of sleep and hardly eating food. I was functioning on Coca-Cola, Lucozade, and spliffs. Basically I was ill for 6 months and continue to smoke without knowing the reason for my sickness. 6 months later, I hit a brick wall, and my body started to shut down. I went from 17 and a half stone down to 12 stone in 6 months. I started getting stomach cramps, stomach pain, vomiting from time to time gastro problems, hypnic jokes when trying to sleep. Tinnitus in the ears. Body shaking once I did fall to sleep when I woke up with tremors. Muscle spasms. Muscle stiffness. Muscle pain. Bone pain. Muscle spasms in my back . Found it hard to walk. Numbness down my legs. Vomiting and nausea.Waking up with numbness in my arms and hands. Muscle spasms in my throat every time I lie down to try to sleep. Constipation. Haemorrhoids, I could not urinate properly. The Muscle spasms in my throat when I try to lie down, causing my throat to close, and i could not breathe when I lie down. All this time, i was going to the doctor's and getting nothing back from the doctors. But muscle relaxant tablets which I could not take. And sent me for every check-up you could imagine and found nothing. They did find I had developed a hiatus hernia,. I was told by the dr to sleep sitting up due to the muscle spasms in my throat when I try to lie down to sleep. So I had to sleep sitting up. Has more time went past, the muscle spasms in my throat got so bad that I could not smoke because my throat started to close when standing or sitting. This obviously stopped me from smoking. My anxiety and depression were so bad from missing my kids and all the symptoms from the chs and I was still not diagnosed. I felt like I was dying. My nervous system was in a very bad way. I done researching everywhere and came across CHS. I then took this to the doctor, and they diagnosed me with CHS. I continue to work through this whole period. Looking back, I do not know how I got through. But I think the continuous moving of the body was helping me somehow. I started to eat a little better and slowly slowly I started to put my weight back on. After 1 year when I was able to lie down without my throat going into spasms I started to sleep a little better slowly slowly. It's been 2 and a 1/2 years since stopping smoking. After 1 year, I was still in a very bad way, with many symptoms still remaining. Through this whole period, having hot baths with Epsom salts was helping me a great deal. Putting warm olive oil all over my muscles was also helping. Drinking bone broth also helped a lot. After 2 years, my haemorrhoids started to calm down. I was able to go to the toilet better. Both urinating and pooing. It's been 2 and 1/2 years, and I'm still have tinnitus in the ears and spasms in my back and back pain, but it's nothing like the spasms and back pain I had before. I'm still suffering a little bit with insomnia. And when I wake from sleep, my arms and hands still go numb and numbness down the outside of my right leg. The biggest help I have found in my healing period was through cranial therapy. When I start to feel quite good, sometime I would try to drink alcohol and smoke cigarettes. Drinking alcohol and smoking cigarettes seems to bring back some symptoms. I tried to drink sometimes to test my body. But then I realised I could not drink. Same with smoking cigarettes. Some symptoms start to come back. I have come to the realisation that I can not drink alcohol or smoke cigarettes. And obviously cannot smoke cannabis for the rest of my life. Even standing next to someone who is smoking a spliff affects me. I was always a very fit and strong individual and felt invincible. But this whole experience has humbled me. Please look after yourself and your health mentally and physically. The one good thing I can see about CHS is that if you stop smoking weed and live a healthy life it can go away. As I said I still have some symptoms. But I feel like if I look after myself hopefully I pray to God that all my symptoms will eventually go away. it is possible that there is damage done that cannot be repaired from but I am very thankful and go forward with a positive mindframe. It is very good to see that there is information out there for people to find. It did not occur to me to go on TH-cam and type in chs back then. But even the videos on TH-cam here do not talk about half my symptoms. I obviously took chs to the Brim. And maybe I'm very lucky. But it is very good to see there is information out there and people are learning more and more everyday about CHS. If you feel you have CHS the beginner of CHS or you feel you have had it for a while please stop smoking now. Go and seek help. As I said the best thing that I found helped me was cranial therapy and God. God bless you all out there, peace 🙏
Doing the great work, thanks Dr Ethan.
Love this discussion. Thanks. Love what you said about touch and Drs. my childhood Dr was very touchy and diagnosed us almost instantly by pinching pushing and poking. She would then test of course. This was before she even asked a question. Great Dr.
_Due to the way society has been going as of late --_
when people read about some doctor touching you as a kid
... they *MAY* think ... they were ... well ... you know #awkward lol
@@NeonCicadaI do understand that. It’s a shame and an unfortunate overall societal loss. I think both reasonable respect for professionals in all forms has been weakened by lack of real communication with our children and some very bad professionals. I just think speed and economics are the root of the problem and ironically lead to a less productive world.
Some doctors are unaware of this and usually contribute it to foreign substances in cannabis. I have heard of such instances. Interesting podcast and very educational. Great job 👍
Would have been great to ask whether CHS sufferers were taking high dosages all at once or over a period of hours. I tend to keep my high going for many hours by taking smaller dosages every 20 or 30 minutes, but I'm generally not too high at any given time.
Both will aggravate it, the little doses will lead to a slow build and the big one one will cause a release of symptoms followed by a worse recurrence.
Would like to hear about cannabinoid induced psychosis
😂