Dr. Eran Elinav on Microbiome Insights into Personalized Response to Diet, Obesity, and Leaky Gut
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- เผยแพร่เมื่อ 7 มิ.ย. 2024
- Eran Elinav, MD, PhD, is a professor of immunology and principal investigator at the Weizmann Institute of Science in Tel Aviv, Israel, where he co-directs the Personalized Nutrition Project. Dr. Elinav is also a principal investigator at the German Cancer Research Center in Heidelberg, Germany. His research focuses on understanding the complex interactions between humans and the bacteria that reside in their gut and how these interactions shape human health and disease.
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Chapters
00:00:00 - Introduction
00:02:14 - Circadian rhythm of the microbiome
00:12:53 - Lessons from Hunter-gatherers
00:20:20 - Nurturing the microbiome in children
00:30:52 - Triglycerides and cholesterol
00:34:34 - Saturated fat
00:36:01 - Effect of artificial sweeteners on the microbiome
00:51:46 - What causes recurrent obesity
00:53:53 - Impact of caloric restriction
00:55:02 - Intestinal permeability (gut leakiness)
01:15:30 - Bacteriophage therapy and precision probiotics
01:30:20 - Bacterial role in TMAO risk
01:36:09 - Weight gain from smoking cessation
01:37:29 - Tips for diet personalization
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#microbiome #weightloss - วิทยาศาสตร์และเทคโนโลยี
This guy is the kind of scientist I love. Tries very hard to be aware of assumptions and biases, not jump to conclusions, and asks lots of valuable questions in his work. Keep it up!
John Kennedy once said,"The greater our knowledge increases, the greater our ignorance unfolds." What a great challenge this microbiome research still faces. Outstanding interview.
You all are providing a great service to the public writ large suffering from these types of maladies! Thank you!
Thank you for this presentation.
If I had ever heard anywhere before that the gut microbiome had a circadian rythm, well, I had forgotten. And that's only one of the highlighted points in this video.
I don't know how many languages Dr. Eran Elinav can speak, but I am glad English is a language he is fluent in.
Isn’t Eran’s English excellent considering he’s speaking at least another 2 languages all the time (Hebrew and German)! A great communicator!
I love your podcasts so much. I do pretty consistent fasting routines and find it really helps my gut. I’ve tried carnivore a few months when I was having some health issues and that restriction definitely had positive effects and I slowly incorporated certain veggies/ fruits back. I do find if I eat similar foods consistently my body functions very well compared to what It used to. Cutting back drastically on processed foods definitely helps as well. If it wasn’t for all your information you are willing to put out I just really don’t know how down hill my body would have went. You are so much appreciated! 🙏🏼
Totally agree!
Dr Will Bulsiewicz would be a great guest, he's one of the leading gastroenterologists in the US and an expert on the microbiome.
So True!!! Doctor B is an amazing source of practical gut microbiome wisdom and particularly as it can be applied in our everyday lives. I don't know whether or not Dr. Rhonda has ever done a session with him but if not she definitely should. Thanks for bringing that up.
This kind of hype-free research is solid gold. Like everyone else, I want an immediate solution, but that's not how the world works. Getting insight into the long, complex process is worth much more than empty promises.
Love your format, very informative! I really appreciate, that you put descriptions whenever you speak about a compound or other, it's very easy to understand. Thanks!
Absolutely EXCELLENT information. Thank you!!
This is hugely informative and quite interesting. I am fascinated by the gut microbiome and on this podcast, I was well served. Thank you for your beautiful work.
I've been following you for 4 years now, you are brilliant, thank you. And also you are absolutely radiant. Glowing. That collegen and sprouts shake is working.
I am in awe. The best by far video of functiona medicine on the mibcrobiome. What a discovery was Dr Elinav. Kudos Rhonda and all. What knowledge you are giving us!
Wow, thank you! Glad you enjoyed it!
This field is Exploding in awareness and understanding of impact on our health. I appreciate all I can learn concerning this. Thank you so much for sharing this information here. Blessings. 😇🥰
Its not actually the research is all out there its just surfacing now. Eat plant variety alot avoid oils fats meats animal products eat starches ad libitum fruits veggies thats it
@@njkel.8714 Even essential fats?
@@RobertWadlow292 no such thing as essential fats. All fats will block srtery at some level even olive oil or fish oil
@@RobertWadlow292 you will produce short chain fatty acids such as butyrate when you consume enough fiber literally in your gut the hesltgiest type of fat
@@njkel.8714 If fats block the arteries, then why do people's coronary calcium scores decrease when following a high fat diet?
Amazing scientist and amazing conversation!
Fascinating. Such important work you do, both of you.
Fantastic interview, constant attempts to bring in nuance and objectivity which I very much appreciate. Thanks!
Project CGM in combination with food testing is planned for this year, can't wait.
Love and strength,
Thomas
This is groundbreaking information. Love it!
Great show! Here's a question: If we eat food we grow in the back yard, would our gut microbes welcome their "neighbors" which come from the same physical area where the host lives? Is there data on the gut biomes of farmers, gardners etc. who eat the food they produce themselves?
Beautiful thought
One of the best talks in microbome research! Best wishes!
Such a great interview! Thank you 😊
SUPER EXCITED ABOUT THIS SUBJECT! Thank you Rhonda! (:
thankyou for editing the references into the video
Good guest; I look forward to seeing a follow-up interview as his research progresses.
Glad Dr. Rhonda suggested studying the effect of stevia, monk fruit and erythritol o the gut microbiome. Eager to hear the results.
There is one point that would be interesting to deepen and that is about the circadian rhythm.
It appears that melatonin has an impact on the microbiome, which would make exposure to sunlight even more important, a habit we have lost with the modern lifestyle.
Wow 💚🙈 wasn't expecting to learn such fantastic info. I thought I knew enough to know how this conversation was going to play. Silly me. Thank you!!
This podcast was fascinating.m thank your, once again.
Regarding the study cited at 1:10 on "Personalized Gut Mucosal Colonization ..." that showed that about half of the individuals responded to probiotics, while the other half did not, I am curious how long they followed this, and might it have ultimately changed if extended far enough, or is it the case that some individuals will just never respond to certain probiotics? The Sonnenburgs talked about it taking years to shift the microbiome, and that has been my N of 1 experience. Two years ago, I had to avoid high fiber foods such as burdock root; after banging away with higher and higher fiber and daily intake of sourkraut, kefit, natto etc, now I can stomach about anything. It was a very gradual change, that took many months.
Your experience seems to be consistent with the observation mentioned by Dr. Elinav that obese people retain their micro biome composition for a very long time after their initial weight loss, and therefore tend to regain the weight soon after ending their diet (yo-yo obesity). I’d say Persistence and taking a gradual approach is the key if one wants to correct any food intolerance (or autoimmune related gut malady) by slowly cultivate and nurture the good bacteria until they find a foot hold in the system.
Very interesting, if i eat sauerkraut or yogurt my gut feels fine, but if i eat fiber ( except for avocado ) my gut feels like crap. I bet there's a dose dependent action, like eating 2-4 pounds of homemade yogurt or kefir would help heal a lot.
I'm about 2/3 of the way through but so far, Eran was fantastic. Very unsciency answers to very sciency questions, making this complex topic very understandable.
Unsciency to all things sciency . Very well put .
Thanks Rhonda. Great information
Great episode 👍
Great info fromDr Elinav!
Thank you
Very interesting conversation
Professor is such a charmer when he smile, very cute guy…and clever!!!!!
I'll leave this comment in case he reads it and the biological response to compliments somehow enhances the microbiome!
How I wish this interview would had been subtitled🙏
Great stuff, Rhonda.
Masterclass. Thank you FMF 🙏
Thanks, Bel!
Am I the only one who thinks there is very little practical information? Its all very technical and he goes deep into some of the mechanisms how things work. Its "nice to know stuff". But he didn't really give any real life advice on what foods tend to be good for most people or at what times it is good for most people to eat. He even says fiber is good in general, but not all fiber, is equal without even mentioning which foods tend to have "good" / "bad" fiber.
I agree with you. That's how real research works, though. When you see people saying consume this, or that, this one thing will make you live longer, avoid cancer, etc, this isn't science. Some people extrapolate from science and come with exaggeration. They're the ones selling books, supplements... easy to recognize. Even sensible, serious scientists are getting on the bad band wagon of exaggeration to make profit. Sad.
@@dianal.1279 I disagree. You can recommend things without selling supplements or books. Rhonda and Doctors/Researchers recommend things like Sauna, cold showers, Vitamind D, Omega 3 and healthy foods all the time. His recommendation was something like: "A lot of what your grandma said is true." Yeah, that true research...
I rather had the feeling he didn't want to recommend anything, so people will buy his book or use the app.
@@xDomGrox Well we cant know for shure, but i dont share the feeling that he held information back to sell us anything. I think he was rather cautious to recommend anything because there is so much we dont know yet. I was somewhat disappointed too about the fact that there was so little practical information, but that's what it is. I think it's quite honest to leave it at that. Hope there will be more "useful" information in the near future :) it's SO confusing atm!
@@OmaKahn Whats the point of doing this kind of research, if he can't give practical information or lifestyle advice? I don't know how long he is researching this topic, but it is at least 5-10 years. You can't tell me he can't recommend any foods, herbs, spices or anything that is good for most peoples microbiome.
@@xDomGroxthough I too wish there were more, there were a few takeaways:
Environment/lifestyle is a much bigger factor for healthy gut microbiome than genetics (awesome because we can take things into our own hands.)
People who are living in extremely poor areas that eat basically the same thing everyday had the most diverse microbiome.. I think this is due to so much skin/soil and skin/animal interaction, no hand sanitizer!!!(and over disinfecting/soap in general), literally zero emulsifiers/food dye/stuff that prolongs shelf life in food, I assume less plastics that end up in the body (for sooo many reasons from food/beverage/cosmetics/etc.), on average people sleep with more "normal" wake-sleep cycles unlike countries where we stay up all night watching Netflix/working/partying. They do more NEAT (non exercise activity thermogenesis). And of course, with medicine/doctors not as available, babies who have abnormalities or pregnancies with complications are less likely to carry all the way to birth which is sort of its own natural selection as harsh as that sounds.
We can increase our next generations microbiome by letting them get dirty, touch animals, eat some dirt, and not over disinfecting their environment. Of course also feed them a healthy diet and get them active.
Grapefruit have some beneficial compounds for healthy fat metabolism (even though it takes much, much more for some people- I totally bought a grapefruit lol).
A big reason why the yo yo dieting weight regain affect occurs is our microbiome. And we can indeed change it! In my opinion this is a solid reason to diet with healthy foods instead of simply relying on a caloric deficit. Obviously calories are the most important factor in weight loss/gain, but if we can focus on making sure we're also choosing healthy options instead of simply low calorie options we may have better long term outcomes!
I'm sure there's more I've missed.
Possibly part of why the conversation went the way it did is to remind us that people who "have all the answers" for what to eat to diversify the gut microbiome are probably full of it. Also he may not want to give recommendations because he really sees how important the individual responses/needs are. I'm a personal trainer and I hate giving blanket recommendations because I see sooo much value in personal approach for success.
I'm so happy my children have a pediatrician who doesn't over prescribe antibiotics. I wasn't afforded the same caution from doctors as a toddler/child.
I hope you let them play in the dirt and not oversanitize around the home. Best wishes 👍🏾👍🏾
Outstanding. Rhonda is the coolist mom in the world.!
You're amazing Rhonda. Thank you for this!
I was disappointed in the fact that he didn’t talk about the types of things we can eat to help our gut microbiome. He briefly stated sleep and losing weight helps, and suggested fermented foods help; however, he mostly talked about medicine opposed to natural remedies we can tackle as well. He comes off as a big pharma type guy.
We get out full 40 hour work week in, in just 3 days. We work Fri, Sat, Sun, before the sun comes up and well after it goes down. I pretty much can only eat super early and super late on those 3 days. This is very good info to have
very informative
Great job
Thank you queen!!! And king!
Interested in knowing about the different fibers that are better or less desirable to keep in ones diet
Where’s the show notes on this? I really wanna reference the grapefruit study. Thank you!
What brand of glucose monitor so you use and how do you use this in your day to day life
This is a fascinating area of study and likely connects with others that you have explored in multiple podcasts. In the case of changing our microbiome to a healthier one is sustainability. Once you introduce the healthy microbiome will changing the food intakes to match that of the healthy donor be enough to sustain it or will other changes be necessary such as the composition of the epithelial cells in the gut? Would eicosinoids need to be generated to change those cells, or some other mechanism? I hope this isn't a dumb question.
Most podcasts waste time. This is DENSE w mindlowing info. Great questions, Rhonda.
GOOD JOB
I find it helpful to slow this video down to help me deal with the accent and not miss the little ideas and inferences. It also gives me more time to read.
Feeding livestock teaches me that changes in diet don't come easy and may take quite a bit of time for the animal to adjust. An animal raised in one feeding program may have a difficult time being successful adapting to someone else's feeding program. The variations in livestock diet is far less than the human diet. Manipulation of individuals traditional diet may be very slow to change and in some cases not possible. The same goes for manipulation of the microbiome.
Just started watching; I hope at some point there is discussion of the best time of day to take probiotics.
~
In regard to changes relating to modern living, it seems one really big change is in overall parasite load and exposure to biting insects. Reduction in both seems like it would have a major effect on the immune system. I've been reading up on heme oxygenase and CO signaling - pretty important & can be altered by exposure to both endo- and ectoparasites. Also, both expose host to CCD antigens. Seems pretty important, too.
@@Vscustomprinting I've had to do a lot of stuff that wasn't easy just to stay alive. Don't tell me what I need - you know nothing about me.
How does a gastric bay pass change the micro biome?
I’ve been curious how simethicone (gas-x) effects the microbiome. When prescribing a higher fiber diet, bloat tends to come with it until your body adjusts. Does simethecone hinder this process like antiacids have been found to do on the microbiome…
What can be done for young adults who had great exposure to IV antibiotics as newborn and now have consequences (hormone problems, endometriosis, migraine, obesity, IBS, depression and anxiety?). Been searching for 24 years. Thank you
I second the motion Dr. Patrick made, around question of 'how Monk Fruit and other natural sweeteners effect microbiome" (I read that stevia does not disrupt, but wish for confirmation). I add this question: How does taking the antipsychotics and antidepressants known to increase appetite, - how do these drugs effect both microbiome as well as ability to manage grelin/hunger signals ?? - even if they are off of these drugs for years.... My loved one who has bounced from one drug to the next, unsuccessfully, now battles many hunger problems from not able to eat, to ravenous, obviously a permanent effect. I think we need to study the biochemical implications of these 'drugs', so more wise decisions can be made before 'trying' them.
Love your video content, it provides a lot of helpful and useful information...!
Can we please get your skincare routine!?!? GLOWING GODDESS
Ok. So, if he knows enough to say the microbes respond differently when you eat during a certain eating window…then he surely has some idea when that eating window is??? Dr. Patrick, any ideas? Many thanks for this episode. I hope you do more on the microbiome.
Amazing questions by Dr Rhonda Patrick and amazing answers by Dr Elan Elinav, especially the leaky gut microbiome. I am always on the lookout for research on this. I have coeliac disease, so it helps to understand. Also keeping the gut healthy is the most important issue to avoid cancel, alzheimer, brain disfunction, diabetes, cardiovascular problems etc. I do intermittent fasting. However fasting is proving difficult at the moment.
What are the options for mothers who cannot breastfeed? What can we do in the first few months?
I understand about letting explore the world in the first 3 years, put some dirt into their mouth, but what about compensating for the lack of breastmilk in the first few months?
Thanks. I enjoy your interviews a lot, Rhonda.
Please look into oxidized poly unsaturated fats. Joseph everrate “what I’ve learned” has put together an amazing presentation on polyunsaturated fats and their apparent horrendous health impacts. As far as I’m concerned sugar is half the criminal compared to them
Unrelated to this particular topic, but have you encountered any solid science on “earthing”?
The answer about omega 3 was not clear at all to me, can you please clarify if it does affect the microbiom positively or negatively?!
He avoids any specificity.
My wife has a history of bulimia, rectal prolapse, stretched intestine, alcoholism, emotional and physical abuse from a narcissistic mother and I want to know what can be done to repair stretched intestine and leaky gut. But after her rectal surgery went bad her mental health got worse which I believe is shriveled up intestine worsening leaky gut symptoms with severe anxiety and depression medication abuse. I seeking help to solve this. Anyone with some knowledge please help. I know collagen and l glutamine helps and leaky gut diet but what else and how do I talk to her to follow a leaky gut diet? Please message me back if you think you can help and give more details, thankyou.
Yoyo obese microbiome answers my celiac trashed microbiome continual struggles. Wow. Wow. Wow. Oddly - I figured this ALL out on my own. I make my own strain-specific dairy-free kefir ONLY bc it was the only way to get my whole body health calm. Celiac, hashi’s and more… childhood strep throat caused antiobiotics 2x / year, it trashed my system. Took 5 decades to solve, which I’ve done. Science is catching up to confirm. Merci!
Does FoundMyFitness do blood work pannel reviews for those suffering with GERD?
Have you tried k2?
@@davidford8539 intermittently. I used a D & K dropper. What are you recommending and the basis behind it. Id love to hear.
@@loganlangston5250 I know someone with gerd, who went on a d3 plus k2 supplement and the gerd went away….could be coincidence, but nonetheless I thought I would mention it, in case it does in fact help.
Would love to hear the probiotics you recommend, and what your thoughts are on the company called “Seed” and their double capsule probiotics
This video, which is similar to this one and excellent, suggests almost no lasting benefit from probiotics th-cam.com/video/s3MZjgtvEQ8/w-d-xo.html
@@allenemersonn1227 would it not introduce bacteria that wasn't present before in a persons body?
Eating prebiotics from fiber rich foods is way more effective and sustainable than simply throwing a few million bugs in a bug environment of billions.
@@angeloselarja I understand now, do you know of a resource which can lead me to see what bacteria certain fiber foods host?
@@jamescommagere7906 Prebiotics are not live organisms. Rather they are "food" for our microbiome. In my opinion, feeding your microbiome is more important and way more effective than simply adding a few more organisms via probiotic consumption. Not that its wrong, but i wouldn't depend on it as the sole strategy. So regarding what you asked, prebiotics are basically fibers, therefore consuming fiber rich foods is highly recommended while at the same time limiting refined/processed ones. So focus on whole plant foods (whole grains, beans, lentils, nuts, seeds, fruits, vegetables.. etc). Even spices such as turmeric and ginger as well as green tea have shown beneficial effects on the microbiome. Omega3s also, so make sure you eat oily fish or take supplements. So to sum up, load up on whole plant foods, spice things up, cover your omega3s needs, and I personally think lowering the consumption of meat and dairy is of importance too (in terms of gut leakiness).
This guy has obviously never answered a question with specificity in his life. He seems to speak in nonspecific circles involving too much unnecessary wordage. I wish that Dr Patrick could have teased more answers out of him. He is a true enigma wrapped in generalities. The expression on Dr Patrick's face says it all.
I bet I could guess his political affiliation
What is your opinion of consuming kefir?
Oh, and I'm a shift worker too and appreciated the discussion on that.
Kefir is bs have boiled potatoes fruits or plants for fiber. Avoid cholesterol
@@njkel.8714 Avoid cholesterol and shrink your brain right? Eat potatoes and spike your insulin right?
@@aloevera7422 brain runs on glucose not cholesterol,your body makes the cholesterol dialy u need through the liver why injest more and cause problems? Insuline should be spikes nothing wrong in that as long as fat intake is low youll never get insulin resistant.
This similar video suggests a diet rich in fermented foods and high in fiber are the most helpful to our microbiome. th-cam.com/video/s3MZjgtvEQ8/w-d-xo.html
@Taiwo Omotosho corn why would corn cause problem when latin amerrica for centuries was fueled by corn. Dairy gluten i agree. Only 1% of the population has problem with gluten MOST DONT. Its bs to bash bread.
interesting message. I notice your face is very shiny! did u just put like some coconut oil on it? for future filming you might want to take all oil off it then dust it with translucent powder that will eliminate the shine factor. thats what tv studios do.
If you like these subjects on micro biome, fasting, weight regain, and immune health, then you have to check out how Joel Greene has been addressing these exact issues in the real world. His book The Immunity Code addresses these issues in direct actionable ways.
Would you mind giving an example?
@@ube4856 apple peels+HMOs,+red polyphenols to feed akkermansia and bifidobacteria
Go find an interview with him and watch it. He talks about much of the larger easier things one can do in them, but his 2 day core eating pattern is everything from this conversation on the micro biome, fasting, and immunity.
why is he talking about studies with saccharin when it has long been proven bad and is not used anymore, at least by Keto folk - I want to know the effect of erithritol, allulose, etc, the new generation of sweeteners
I was thinking the same.
Maybe they were either older studies or maybe saccharin is more widely used in Israel?!?
Effects of Sweeteners on the Gut Microbiota: A Review of Experimental Studies and Clinical Trials - pubmed
Is there a way we could possibly reverse the effects of antibiotics by getting a culture of the Micro biome before you give someone antibiotics? Then re-administer a “clean” culture back to the individual after the effects of the antibiotic are gone?
@@tunneling-nanotubes Kinda, it’s theorized that you appendix works as a Storage facility for different types of bacteria. The problem I see is that an anti biotics will profuse through all tissues including your appendix, possibly killing that storage of bacteria In your appendix aswell. So although that might help if you get infected with something or had something weird going on where the balance of different bacteria got out of wak. But I don’t think it will help with antibiotics unfortunately.
Lucy Mailing was trying to get investors interested in a start-up for personal stool / microbiome banking - don't think there was enough interest due to the cost of the service.
@@tunneling-nanotubes It would be interesting to see if the reestablishment of the microbiome still happens even if you don’t have your appendix.
At what time in the video does he imply the microbiome regenerates itself? I’ve been trying to look for it
@@salk2306 idk man you would have to ask her
So he's saying eating prebiotic and fermented foods may not change gjt microbiota is some individuals? What about the Stanford July 2021 study where they found fermented foods lowered inflammation?
He mentioned that the effect is individualistic. It works well in some individuals and not so well in others.
Rhonda is so shiny. ☀️😎
💕
Choline from eggs is bound to phospholipids therefore it can't be converted as easily to TMA. Interventional trials have failed to link egg consumption to higher TMAO levels.
How about supplemental choline?
@@brothercaleb no phospholipids. Krill oil has choline with phospholipids
Recommended: Dr. Will Bulsiewicz MD
Never take ibuprofen leaky gut risk and microbiome destruction
Can I take an aspirin tho?
This is quite frustrating, same situation with the question regarding effect of fasting on microbiom...the answer he gave...was technically no answer!!
I agree
So how to colonize our gut properly?
Faecal transplant 👀
The adult human body has about 5 pounds of friendly flora gut bacteria that represent about 80 percent of the immune system function when this friendly flora microbiome bacteria is functioning well supported by the correct diet of the host. Of course, this is today easier said than done when we consider all of our food distractions and real addictions including wrongful food choices that harm the diversity of the intestinal tract.
I feel it is wise today to eat what your ancestor's forefathers ate in the season when by default every food was organic as nature intended it to be. You can compare your microbiome to the topsoil of this good earth. If the nutrient is not found in the soil for example vitamin B-12 then it will be not found in the food that is growing in such soil that is missing essential elements treated with sterile fertilizers that contain limited elements for fertilization.
When our body dies and decomposes we actually become part of the soil and I see this in my garden every day when composting and seeing small mammals .amphibians , reptiles, and insects decomposing into my fertile topsoil. The pre-biotics of dietary fiber is so essential to support the pro-biotic life inside the intestinal tract every day throughout one's life. To avoid the symptoms and intestinal malfunction of the intestinal tract called Metabolic Syndrome that will cause all kinds of bodily symptoms unexplained to your MD would have normally materialized over weeks or even months of wrongful eating drinking and living a wrongful lifestyle. The first sign of metabolic syndrome is the lack of not having at least one bowel movement every day of your life.
Your weight distribution is extremely important as well . If you carry a large belly this is most likely a sign of a lot of unwanted visceral fat around your liver and other organs including your pancreas from eating way too much-cooked food.
Basically depending on where you live my recommendation is to support your local organic farmers in season including farmers' markets and to diversify your food intake by learning to prepare your own meals like what are ancestors' forefathers have been doing for millions of years before our time. Many thin edible skins must be eaten as this is a very important pre-biotic food for the probiotic-friendly flora bacteria that resides in your intestinal tract. Thank you
SEAWEED is so essential to support metabolism and health for your thyroid gland located at the base of your neck an organ that regulates your hormones . 4 Sea vegetables on rotation must be introduced into your diet plan and we can learn this from Japan and the BlueZones the longest living people in the world at this link www.bluezones.com 5 - Yes Insulin excess is not good for the body to control and to lose weight from my research on TH-cam. And yes include your dietary fiber-rich foods from organic sources only or at least your first choice . 6 - Yes SLEEP sound and complete is so essential for the regulation of your metabolism. Learn on TH-cam to regulate your circadian rhythm and you will be so glad that you did. The SAD standard American Diet is frightfully deficient in Green Leafy greens that supply the essential mineral Magnesium and the water-soluble vitamins C and the fat-soluble vitamin called vitamin K-1 ............... Yes, Morning Hydration is so very important and I use vegetable broth and herbal teas water, and other beverages including my famous bio-hack green herbal coffee straight from our organic garden. Yes, plant-based eaters must include vitamin B-12 Nutritional Yeast. Intermittent Fasting is essential as well. Consume the Nature made fats and avoid the big food giant industry process fake fats that will damage you internally and wreck up and slow down your metabolism. 7- Yes intermittent impact exercise taken outside with deep slow breathing through your nose only will increase essential NO NITRIC OXIDE as a gas that opens up your arteries for heart health and for boosting your metabolism.
So, if you live a hectic, stressful life, your microbiome is also stressed, not matter how "healthy" you eat. If your diet is not very varied BUT you live a stable life, your microbiome will be stable and healthy.
If fats (nuts, nut butter, full fat dairy, avocado etc) are more satiating, what does that say about your microbiome ?
Maybe it just turns on the chemicals that tell the brain you're full? Not sure microbiome would affect feeling full and release of those chemicals, but it may be different for some people. Never really heard anything on this though, besides fat makes you feel full. Interesting question
@@mmhthree Yes maybe. Its a commonly agreed on concept in the weight lifting community that protein is more satiating than other macros. But say I have either, a snack to hold me over til the next meal - (all things being equal), a fat dominant snack such as walnuts or avocado will most definitely hold me over better than say - the chicken breast. Also, if I diet and construct the macro ratio so that it is biased towards fat as opposed to carbs (even complex) I will do better.
well one thing fats do is tell the gall bladder to dump bile therefore killing off many small intestinal bacteria, so fats definitely affect the micro biome, this is the normal function and why eating lots of good fats keep reduces SIBO, eating lots of carbs kind of spoils the function encouraging SIBO and bad bacteria, carbs are less satiating because they are addictive, encouraging you to eat more and more... fat does not do that
Naringénin
This is worth more than all of the probing of the galaxies.
A healthy fruit? One sans fructose?
I listened to this interview as a podcast rather than a TH-cam, my take from Eran is that research into the microbiome is that it is still very early days and there is not much clinically/practical outcomes. Rhonda kept asking leading question hoping to find that there was research that plant compounds/fibre is good and meat/saturated fat was bad for the gut and health in general, but Eran would not commit to any of this. As a 65 year who has had form of colitis 20 years and quite a few other medical conditions, adding lots of uncooked plants and fibre only makes the colitis worst.
Have you looked into your gut health. An unhealthy gut will not be able to tolerate uncooked vegetables. There are tests available to check.
Since Rhonda still eats meat, I doubt she had any agenda in asking about the plant compounds.
1:39:00
She should have corrected him that the FDA would not be in the role of approving probiotics. That is outside their jurisdiction.
Aajonus Vanderplatz nailed this stuff down years ago…eat raw meat your gut micro biome loves it… you’ll get both fit and healthy by eating alone.
You cannot loose and maintain weight loss eating sugar, starch, grains and high glycemic vegs and fruit.
So it seems that a person would have to take weight off very very slowly and add micro nutrients
Rhonda, your skin is luminous and shiny. How do I?
Superfluous 😜
chenge your lighting
I really appreciate the contents of this channel but sometimes it is vexing that Rhonda uses ‘you know, you know’ so many times in the middle of sentence or especially when she poses questions....
My perfect diet is fatty fish or meat with fruit. It balances me out perfectly. Maybe that's the perfect human diet.
So those doctors that say calories in are what makes you fat. It is shaming and wrong.
hmm, lotsa "how we build the clock" stuff and not enough of simply spitting out what time it is.