TEMPLE OF HADES - DAMAGE CAP (4.2 Bi) - PISCES APHRODITE - CRATERIS SUIKYO

If you have:
Sufficient Defense Pierce (over 1300, ideally) . Equip the Cosmo mixer, Cosmos with an inscription.
The Heavens and Earth Cosmo to boost Defense Pierce.
With all these in place, you should be able to "break" the boss's defense.
Tips for Aphrodite:
He always targets the summons.