New video uploaded in my TH-cam Channel ! Iron Deficiency Anaemia : Topics include: -What is Anaemia & Iron Deficiency Anaemia -What is the Role of Iron in Our Body -Iron Sources -Iron Absorption & Role of HFE gene in Haemochromatosis -Iron Storage -Ferritin, Haemosiderin & Transferrin -Common Causes of Iron Deficiency Anaemia -Why It is common in Children and Women of Reproductive Age -Clinical Features - Anaemia & Epithelial Tissue Clinical Findings -Plummer Vinson Syndrome -Lab Diagnosis -Iron Profile Findings -Treatment options Hope it is helpful
I am a pediatrician in the USA. Well done: slow, succinct, clear ,with logical progression.Have recommended to residents here, and subscribed. Thank you, J.M. Roberts, M.D.
I sincerely appreciate you Dr igho on TH-cam, and you do have my full trust, you should be heard around the world, because of your super herbal medication, thank you so much for I'm free of Anemia I had thought this would never end
I last watched you in my second year and now i am in 5th year and you are still blessing for us ❤️ love from india sir 🙏🏻 They way you teach is amazing
Thank you for your feedback. Take care and stay blessed. Here is a link of my new immunology video on transplantation and graft rejection. th-cam.com/video/o2vm2Sh1W84/w-d-xo.html
I m from india,I m medical student here in china.I have watched all of ur vedios sir.its really really helpful,clear n conceptual..may god bless u sir..once again thanku so much for such a good lecture...
I have been suffering from iron deficiency anaemia for 8 years now. Thank you for teaching me about my condition in such a scientific, pragmatic way! I now know how to talk to my doctor about figuring out the underlying cause (which no doctor has ever tried to do) and proper dose! (Most iron I've been on is 150mg once a day, no wonder it's been 8 years and my stores are still stageringly low!) A thousand times thank you! Can't say it enough! =)
Janice Exel Thank you very much for liking my video and for your kind comments. Glad to know it was helpful. Please do visit your doctors and follow their advices regularly. How ever please do not change any drug dose on your own without consulting your physicians. Hope you get well soon. Best wishes from Bangladesh.
Love your accent. A lot of great information. Public speaking classes would not appreciate the “okay”, but for me, it helps me separate the thoughts being stated while maintaining the connection of thought from one statement to another. I am no medical student yet I understood the lesson. Great job! Also I am learning this for my own health, and I can recognize how to apply the information. Thank you!
Glad to see the video ...this video is most useful. For medical students . I request to Dr rabiul haque to prepare more videos that may be helpful for students .
Hi Doctor, I was amazed to see your video. It complements my studying notes. Thank you so much :) I will be looking at all your videos from now and subscribing. God bless you
Thank you Doctor Rabiul Hague. My Iron and B12 is normal range but my RBC, Hematocrit and Hemoglobin are low but not very low. I think I am Iron Deficiency Anemia. Once again thank you very much. From 🇺🇸
Thanq sooo much sir... Got a clear understanding abt Iron deficiency anemia after watching this video.. Very much useful during exams.. Would like to watch more videos on pathology..
I am 6 weeks pregnant and my blood test shows Ferritin only 3,1 while the hemoglobin is 12,4. I have been listening the entire lesson so by definition I'm not having anaemia so my question is : Why is the ferritin level so very low. Before watching your video I was sure I have anaemia because I'm also feeling extremly tired all though I sleep enough. The last 4 days I've been most of the day time in bed.I am afraid I may be very sick and not knowing that.If you read this and have time and u do have an explanation pls do write me your opinion. I forgot to mention that I'm 35 yrs old. Thank for posting this video.
Thank you for liking this video. My newer videos are recorded with a better camera ! You can check them out too ! Take care & stay blessed. Best wishes from Bangladesh. :)
well done but we were waiting for more explanation on the role of ferritin and why do we usually ask for it in iron deficiency anemia as part of laboratory work up in iron deficiency anemia and what about TIBC....yet it is well done overall and many thanks .. i am Dr. naji Abdel -Samad from Lebanon.
Peace be upon you. Hello Sir , Thank you for liking my video. I am having net problem. I will try to answer your questions in detail tomorrow (cant write using phone) . I will add a note in my facebook page and mention the link here. Take care doctor. Best wishes from Bangladesh.
Hello, I have made a slide about iron profile and uploaded it in my channel's Facebook page. Here is the link : facebook.com/Pathology.Tutorials/photos/a.503232946462988.1073741829.491432484309701/530301053756177/?type=1&theater To say in short: To understand iron profile it is important to understand stages of iron deficiency first. When iron is deficient , at first the storage iron begins to deplete. That means ferritin (storage form of iron ) begins to deplete. Serum iron remains normal initially. But when ferritin begins to decrease hepatic macrophages can recognize it and they begin to pump out more and more transferrin into the blood with a hope to gather more iron. So transferrin increases. That results in increase TIBC ( Total Iron Binding Capacity ) . Recall that Transferrin is the measure of TIBC. The more transferrin in the blood the more iron can bind with it. So Total Iron Binding Capacity will increase. In second stage , storage iron is depleted and serum iron also begins to deplete. In third stage Normocytic Anaemia develops. The mechanism is - bone marrow is still able to make RBC of proper size and of proper MCH , MCHC and MCV but in reduced number due to iron deficiency. In last stage iron deficiency is so severe that bonemarrow cannot maintain MCV, MCH, MCHC of RBC and microcytic hypochromic anaemia results. Hope it is helpful. Thank you for liking my video. My newer videos are shot with better camera. More videos coming soon ! Take care and stay blessed.
Hello. I would like for you to look at my iron overload profile. I have tested negative for hemochromatosis or thalassemia. How ever my ferritin is high and my hemoglobin continues to not go beyond 10.
I've a qs please, as I know that the conversion of Fe3 into Fe2 at the beginning of the Iron absorption is done by a ferroreductase enzyme, called the duodenal cytochrob B-1 (cytB1) , is it the same as Vit.C? thanks in advance!!
thank you alot doctor it's helping me to understand pathology in much easy way ...all the way from India.. sir can u tell what is the pathology behind the brittle nails??
i feel really really tired all day(although ive slept enough) , my heartbeat is faster than usual and also i am often short of breath. it really disturbs me a lot and im not sure if it's anaemia
you should have covered more on malabsorbtion of non-heme iron because not only indian subcontinent has more vegetarians but world is becoming progressively more vegetarian ... covering more or less entire set of bad habits vis-a-vis iron in diet be it cooking or be it not knowing what promotes or inhibits non-heme iron would be helpful ... prevention is better than cure ... a doctor needs to know these things because he faces ignorant patients on daily basis
If Anemia affect legs, it will be reversable? I have pernicious Anemia hence B12 deficiency. It had effected my balance coordination but now my balance is almost ok but my feet still cramped.
Hello ! Thank you for your feed back. When there is iron deficiency - first the storage iron begins to deplete. Storage iron means ferritin. When ferritin depletes - Macrophages of liver can detect it and they begin to pump out more and more transferrin in the blood in response. Transferrin is the measure of TIBC. The more transferrin in the blood - the more iron can bind with it . So TIBC INCREASES in iron deficiency. You can check out the following link from my channel's Facebook page for more info. Following lines are taken from my channel's facebook Page : I have made a slide about iron profile and uploaded it in my channel's Facebook page. Here is the link : facebook.com/Pathology.Tutorials/photos/a.503232946462988.1073741829.491432484309701/530301053756177/?type=1&theater To say in short: To understand iron profile it is important to understand stages of iron deficiency first. When iron is deficient , at first the storage iron begins to deplete. That means ferritin (storage form of iron ) begins to deplete. Serum iron remains normal initially. But when ferritin begins to decrease hepatic macrophages can recognize it and they begin to pump out more and more transferrin into the blood with a hope to gather more iron. So transferrin increases. That results in increase TIBC ( Total Iron Binding Capacity ) . Recall that Transferrin is the measure of TIBC. The more transferrin in the blood the more iron can bind with it. So Total Iron Binding Capacity will increase. In second stage , storage iron is depleted and serum iron also begins to deplete. In third stage Normocytic Anaemia develops. The mechanism is - bone marrow is still able to make RBC of proper size and of proper MCH , MCHC and MCV but in reduced number due to iron deficiency. In last stage iron deficiency is so severe that bonemarrow cannot maintain MCV, MCH, MCHC of RBC and microcytic hypochromic anaemia results. Hope it is helpful. Thank you for liking my video. My newer videos are shot with better camera. More videos coming soon ! Take care and stay blessed.
Thank you for your feedback. I already have videos on neoplasia and rbc disorders. Please look into "videos" section of this channel (click "load more" or scroll down if required). This channel has 76 videos on various topics so far. Link: th-cam.com/users/DrRabiulHaquevideos
Dear doc ,so nice. Make a good presentation with good pictures like Dr Ajit virkut of India . You are young make a team .and make best of lectures. And remove your older vedios with new lectures .why you are ashamed of dhaka Tell that iam from Dhaka .be proud of your nation .make a good team and make word best e book . Aashish Dr nagar india gynecologist
Thank you sir for your feedback. Due to copy right issue I did not use images in my old videos. My newer videos have self drawn and computer rendered images. Upcoming videos will have self made 3D rendered animations as I have been learning it for one year (Test animation already used in title of my last video of leukaemoid reaction). Any copy right free image is always welcomed (specimen or histopathological images) that I can use attributing the source or person. I also have plans to start haematology and histopsthology slide sessions in the future. My city and current designation is shown in most of my video titles. I sincerely agree that everyone should be proud of his own nation and I am also proud of mine. Any suggestion and feedback in other videos are always welcomed. Take care and stay blessed. My best wishes for Dr Arjit sir's channel.
My hemoglobin is 3.0. They wanted to give me 3 units of blood. I don't want to take it cause the transfusions make me sick. I take iron pills 2 times a day. Any suggestion for me?
Haemoglobin 3 is a life threatening condition, urgent blood transfusion is needed to correct it quickly, please follow your physician's advice quickly.
Fe³⁺ it is converted on the surface of the duodenal mucosa at Fe²⁺ ( under the influence of a reductase ) , this being transported to the cells of the duodenal mucosa with the help of a Fe²⁺ - H ⁺ cotransport system
Hello, I took help of the following Books to make this video. 1. de Gruchy's Clinical Haematology in Medical Practice (5th revised edition). 2. Rapid review Pathology : Edward F Goljan (3rd Edition, South East Asia Region) 3. Robbins and Cortan : Pathologic Basis of Disease (8th Edition) 4. Kaplan Biochemistry Review Book (For Iron Metabolism) Regarding your second question: HFE gene products have a role in iron absorption. Our body tries to absorb iron at around 1 mg/ day. 10 % of our dietary intake of iron gets absorbed. When there is mutation in HFE gene , too much iron will be absorbed. ( eg. 2 mg/day , 3 mg/day etc. which will result in iron overload slowly (e.g in 10/20 years). If I want to be more specific HFE gene products helps plasma transferrin to bind with it's mucosal cell transferrin receptor. Then transferrin can be endocytosed inside mucosal cell and take up iron and take it to different tissues via blood. Amount of endocytosed transferrin determines how much mucosal cell iron gets released into plasma and binds to transferrin. That's as far as I know. You can look into Biochemistry Text Books if you need more info. Again, Thank you for liking my videos. My newer videos are shot with better camera. Take care & stay blessed. Best wishes from Bangladesh. :)
I thought Ferroportins kick iron out without the need of transferrin coming in and picking them up. and TfR are only found on cells that need iron, such as RBCs. But I guess you are right since all cells technically need iron including the enterocyte themselves. Let me know if any of what I said is wrong. Thank you for the vid it was great and I hope you continue recording videos. They are really helpful. Best of Luck!!
New video uploaded in my TH-cam Channel !
Iron Deficiency Anaemia :
Topics include:
-What is Anaemia & Iron Deficiency Anaemia
-What is the Role of Iron in Our Body
-Iron Sources
-Iron Absorption & Role of HFE gene in Haemochromatosis
-Iron Storage
-Ferritin, Haemosiderin & Transferrin
-Common Causes of Iron Deficiency Anaemia
-Why It is common in Children and Women of Reproductive Age
-Clinical Features - Anaemia & Epithelial Tissue Clinical Findings
-Plummer Vinson Syndrome
-Lab Diagnosis
-Iron Profile Findings
-Treatment options
Hope it is helpful
Rabiul Haque Dear sir thanks a lot for so nice lectures. --Dr.Tated Rajesh, Aurangabad (Maharashtra )India
Glad to know it was helpful, ALLAH bless u too and best of luck.
Sir all lec of anemia avilble
Today is my exam...and i have learnt this whole q in just an hr ...😍😍 thank you so much
I guess it is pretty randomly asking but does anybody know of a good website to stream new series online?
@Nathanael Marcel Flixportal :D
@Ashton Alex Thank you, I signed up and it seems like they got a lot of movies there :D I appreciate it !
I am a pediatrician in the USA. Well done: slow, succinct, clear ,with logical progression.Have recommended to residents here, and subscribed.
Thank you,
J.M. Roberts, M.D.
+jrobe628 Thank you sir for recommending my video and for subscribing. Best wishes from Bangladesh.
jrobe628 More to read about this topic mediculture2018.blogspot.com/2018/05/iron-deficiency-anaemia.html
I sincerely appreciate you Dr igho on TH-cam, and you do have my full trust, you should be heard around the world, because of your super herbal medication, thank you so much for I'm free of Anemia I had thought this would never end
Finding videos helpful after 7 years of publication.May Allah bless u SIR
Alhamdulillah. Thank you for your feedback. Take care and stay safe.
im doing medicine in Saudi Arabia,and im using ur video as source for studying its really so helpful,ALLAH bless u .
Best lecture sir ..May Allah bless you with health nd knowledge..keep shining nd uploading lectures.. your online student from Pakistan 🇵🇰
Thank you for your feedback. Take care and stay blessed. :)
I last watched you in my second year and now i am in 5th year and you are still blessing for us ❤️ love from india sir 🙏🏻
They way you teach is amazing
Thank you for your feedback. Take care and stay blessed. Here is a link of my new immunology video on transplantation and graft rejection. th-cam.com/video/o2vm2Sh1W84/w-d-xo.html
I am a medical student in Nigeria. Thanks a lot for this video, I love it.
Thank you for liking my videos. Best wishes from Bangladesh. :)
I m from india,I m medical student here in china.I have watched all of ur vedios sir.its really really helpful,clear n conceptual..may god bless u sir..once again thanku so much for such a good lecture...
Thank you for liking my videos. Take care and stay blessed. Best wishes from Bangladesh. :)
I have been suffering from iron deficiency anaemia for 8 years now. Thank you for teaching me about my condition in such a scientific, pragmatic way! I now know how to talk to my doctor about figuring out the underlying cause (which no doctor has ever tried to do) and proper dose! (Most iron I've been on is 150mg once a day, no wonder it's been 8 years and my stores are still stageringly low!)
A thousand times thank you! Can't say it enough! =)
Janice Exel Thank you very much for liking my video and for your kind comments. Glad to know it was helpful. Please do visit your doctors and follow their advices regularly. How ever please do not change any drug dose on your own without consulting your physicians. Hope you get well soon. Best wishes from Bangladesh.
For iron deficiency let's know about best syrup 👉
th-cam.com/video/yXqUTJf-HH0/w-d-xo.html
Janice Exel get well soon.
thank q sir.me medical student fro nepal,n i heartly appreciate Ur way of teaching methodology...we want your more video thoroughly sir...
Thank you for your feedback. Take care and stay blessed. :)
Love your accent. A lot of great information. Public speaking classes would not appreciate the “okay”, but for me, it helps me separate the thoughts being stated while maintaining the connection of thought from one statement to another. I am no medical student yet I understood the lesson. Great job! Also I am learning this for my own health, and I can recognize how to apply the information. Thank you!
Thank you for your feedback. Wish you all the best.
Glad to see the video ...this video is most useful. For medical students .
I request to Dr rabiul haque to prepare more videos that may be helpful for students .
+SIDHARTHA NAYAK Thank you for liking my video. Take care and stay blessed. Best wishes from Bangladesh. :)
Listened to this in 2014..back again in 2022.....expensive and rare Information. So helpful...thankyou
Thank you for your feedback. Take care and stay blessed.
thank you so much sir i have many problems in this topic IDA.. but there is no problem after watching this lecture 👌❤️❤️
Thank you for your feedback. Take care and stay blessed. :)
Well detailed presentation .Thank you sir !!!❤❤
Thank you for your feedback. Take care and stay blessed. :)
Hi Doctor, I was amazed to see your video. It complements my studying notes. Thank you so much :) I will be looking at all your videos from now and subscribing. God bless you
Coral crue Thank you for liking my videos and for subscribing to this channel. As always, best wishes from Bangladesh. :)
thank u....sir for making ds video...for us...this hlp alot....god bless u...
Thank you for liking my video. Take care and stay blessed. Best wishes from Bangladesh. :)
Tq sir... it is very helpful lecture... Iam a dental student from MGPGI Puducherry
All the best
Prof. S T Ahmed
Canada.
+Syed Tanveer Ahmed Thank you sir for liking my videos. Take care and stay blessed. Best wishes from Bangladesh.
m a medical student...ur video classes r a great help 4 me..may God bless u sir....lukng forward 4 ur more video classes...thanku sir....
Ria Roy Thank you for liking my videos. Glad to know they were helpful. Best wishes from Bangladesh. :)
Thank you Doctor Rabiul Hague. My Iron and B12 is normal range but my RBC, Hematocrit and Hemoglobin are low but not very low. I think I am Iron Deficiency Anemia. Once again thank you very much. From 🇺🇸
You like dr. Najeeb.....slow, clear voice really nice...
Thank you for your feedback. Take care and stay blessed.
Sir u r great love u sir god bless u ,great work ur videos helped me a lot long live sir plz upload pathogenesis of diseases
Thank you for your feedback. Take care and stay blessed. :)
Thanq sooo much sir... Got a clear understanding abt Iron deficiency anemia after watching this video.. Very much useful during exams.. Would like to watch more videos on pathology..
Thank you for your feedback. Take care and stay blessed. :)
I am a student of you from bangladesh....plz give all the video of b pharm..
thank you very much doctor
your videos are so helpful
+Doctor Odat Thank you for liking my video. Take care and stay blessed. Best wishes from Bangladesh. :)
Well detailed and clear lecture. Congratulations and thanks!
Thank you for your feedback. Take care and stay blessed.
JAZAKOM ALLAH KHAIRA .. BEST WISHES FOR U
Thank you for liking my videos and for your feedback. Best wishes from Bangladesh. :)
Thank you so much sir for this awesome video
Thank you for liking my videos. Take care and stay blessed. :)
thank you a million times!
awesome teaching l want information regarding Congestive heart failure...thank you..
Thank you for liking my videos. Best wishes from Bangladesh.
Upload many videos from pathology... It will be helpful during exams tq.
Thank you for liking my videos. Best wishes from Bangladesh. :)
thank you doctor, its a very helpful video...from Algeria :D
Thank you for liking my videos, best wishes from Bangladesh. :)
I am 6 weeks pregnant and my blood test shows Ferritin only 3,1 while the hemoglobin is 12,4. I have been listening the entire lesson so by definition I'm not having anaemia so my question is : Why is the ferritin level so very low. Before watching your video I was sure I have anaemia because I'm also feeling extremly tired all though I sleep enough. The last 4 days I've been most of the day time in bed.I am afraid I may be very sick and not knowing that.If you read this and have time and u do have an explanation pls do write me your opinion. I forgot to mention that I'm 35 yrs old. Thank for posting this video.
Thnk u so much..that's vry much useful
Thank you for your feedback. Take care and stay blessed. :)
thank u
This was a very informative video. Many thanks!
Thank you for liking this video. My newer videos are recorded with a better camera ! You can check them out too ! Take care & stay blessed. Best wishes from Bangladesh. :)
well done but we were waiting for more explanation on the role of ferritin and why do we usually ask for it in iron deficiency anemia as part of laboratory work up in iron deficiency anemia and what about TIBC....yet it is well done overall and many thanks .. i am Dr. naji Abdel -Samad from Lebanon.
Peace be upon you. Hello Sir , Thank you for liking my video. I am having net problem. I will try to answer your questions in detail tomorrow (cant write using phone) . I will add a note in my facebook page and mention the link here. Take care doctor. Best wishes from Bangladesh.
Hello, I have made a slide about iron profile and uploaded it in my channel's Facebook page. Here is the link : facebook.com/Pathology.Tutorials/photos/a.503232946462988.1073741829.491432484309701/530301053756177/?type=1&theater
To say in short:
To understand iron profile it is important to understand stages of iron deficiency first.
When iron is deficient , at first the storage iron begins to deplete. That means ferritin (storage form of iron ) begins to deplete. Serum iron remains normal initially.
But when ferritin begins to decrease hepatic macrophages can recognize it and they begin to pump out more and more transferrin into the blood with a hope to gather more iron. So transferrin increases. That results in increase TIBC ( Total Iron Binding Capacity ) . Recall that Transferrin is the measure of TIBC. The more transferrin in the blood the more iron can bind with it. So Total Iron Binding Capacity will increase.
In second stage , storage iron is depleted and serum iron also begins to deplete.
In third stage Normocytic Anaemia develops. The mechanism is - bone marrow is still able to make RBC of proper size and of proper MCH , MCHC and MCV but in reduced number due to iron deficiency.
In last stage iron deficiency is so severe that bonemarrow cannot maintain MCV, MCH, MCHC of RBC and microcytic hypochromic anaemia results.
Hope it is helpful. Thank you for liking my video. My newer videos are shot with better camera. More videos coming soon !
Take care and stay blessed.
Thank you sir
Thank you for your feedback. Take care and stay blessed. :)
sir,it was a great help. You have not included Mucosal block theory in iron transport. (while you have covered Iron metabolism)
Thank you for liking my videos. Best wishes from Bangladesh. :)
Awesome sir plzz upload more pathology lectures
Thank you for your feedback. Take care and stay blessed. :)
Thank u so much your videos are really helpful
Thank you for liking my videos. Best wishes from Bangladesh. :)
Good Job, Amazing Videos
Thank you for liking my videos. Best wishes from Bangladesh. :)
As always: Very nice explanations. Thank you!
Thank you for your feedback. Take care and stay blessed. :)
Nice one sir....👌
Thank you for watching my videos and for your feedback. Take care & stay blessed. :)
Tqqqqq very much Sir..
Thank you for your feedback. Take care and stay blessed. :)
Nice presentation 😍🤩🤩🤩
ThankYou for helping.😊
Thank you for liking my videos. Best wishes from Bangladesh.
sir, please make lectures on leukemia and other wbc disorders .🙏🙏
Thank you for your feedback. Take care and stay blessed. :)
Hello. I would like for you to look at my iron overload profile. I have tested negative for hemochromatosis or thalassemia. How ever my ferritin is high and my hemoglobin continues to not go beyond 10.
You are the best sir
Thank you for your feedback. Take care and stay blessed. :)
I've a qs please, as I know that the conversion of Fe3 into Fe2 at the beginning of the Iron absorption is done by a ferroreductase enzyme, called the duodenal cytochrob B-1 (cytB1) , is it the same as Vit.C?
thanks in advance!!
thank you alot doctor it's helping me to understand pathology in much easy way ...all the way from India..
sir can u tell what is the pathology behind the brittle nails??
Yes that would be helpful
i feel really really tired all day(although ive slept enough) , my heartbeat is faster than usual and also i am often short of breath. it really disturbs me a lot and im not sure if it's anaemia
can you tell me if these symptoms means I'm lack of iron btw im 14 this year
Thank you . Amazon lectures.
Thank you for your feedback. Take care and stay blessed. :)
Thanks bro
Thank you for liking my videos. Best wishes from Bangladesh. :)
Very helpful!
Thank you Doctor, this video was much of a great help.
Thank you for your feedback. Take care and stay safe. Best wishes from Bangladesh. :)
This video was so much useful, it made so easy to read
Thank you for your feedback. Take care and stay safe.
Thank you so much Dr.Rabiul❤
You are a great teacher..stay blessed Always.
Thank you for your feedback. Take care and stay safe. Best wishes from Bangladesh. :)
you should have covered more on malabsorbtion of non-heme iron because not only indian subcontinent has more vegetarians but world is becoming progressively more vegetarian ... covering more or less entire set of bad habits vis-a-vis iron in diet be it cooking or be it not knowing what promotes or inhibits non-heme iron would be helpful ... prevention is better than cure ... a doctor needs to know these things because he faces ignorant patients on daily basis
Thanks Sir g
Thank you for your feedback. Take care and stay blessed. :)
Thank you!
Thank you for liking my videos. Best wishes from Bangladesh. :)
:-) Sending best wishes back to you..from Boston.
Thanks
+mohamedalamgir haq Thank you for liking my video. Take care and stay blessed. Best wishes from Bangladesh. :)
Wow super understanding sir nicee
Thank you for your feedback. Take care and stay blessed. :)
The best video ever sir would u plz upload video for rheumatoid athritis,osteoathritis and bone related tumor plz plz
Thank you for your feedback. Take care and stay blessed. :)
Thank you Sir ... please make videos on leukemia
Thank you for your feedback. Take care and stay blessed. :)
Don't say thanks sir we are only thankful for u sir....
Thank you for your feedback. Take care and stay blessed. :)
Brilliant🌈
Thank you for your feedback. Take care and stay safe.
Best expalain
Thank you for your feedback. Take care and stay blessed. :)
Great job sir it's really helpful
Life saver ,thank you so much sir
Thank you for your feedback. Best wishes from Bangladesh.
Sir in megaloblastic anemia nuclear maturation leads cytoplasmic maturation
Great sir
Thank you for your feedback. Take care and stay blessed. :)
If Anemia affect legs, it will be reversable?
I have pernicious Anemia hence B12 deficiency.
It had effected my balance coordination but now my balance is almost ok but my feet still cramped.
very helpful ,thankx alot DOC
Thank you for liking my video. Glad to know it was helpful. Take care and stay blessed. Best wishes from Bangladesh.
Thank u soo much sir ...
Thank you for liking my videos. Take care and stay blessed. :)
thank you sir.. that helped alot !
+aayushi asthana Thank you for liking my video. Glad to know it was helpful. Best wishes from Bangladesh. :)
thank you so much sir
+narayani priya Thank you for liking my video. Take care and stay blessed. Best wishes from Bangladesh. :)
is it possible that TIBC is also low iron deficiency anemia? why or why not?
Hello ! Thank you for your feed back.
When there is iron deficiency - first the storage iron begins to deplete. Storage iron means ferritin. When ferritin depletes - Macrophages of liver can detect it and they begin to pump out more and more transferrin in the blood in response. Transferrin is the measure of TIBC. The more transferrin in the blood - the more iron can bind with it . So TIBC INCREASES in iron deficiency. You can check out the following link from my channel's Facebook page for more info.
Following lines are taken from my channel's facebook Page :
I have made a slide about iron profile and uploaded it in my channel's Facebook page. Here is the link : facebook.com/Pathology.Tutorials/photos/a.503232946462988.1073741829.491432484309701/530301053756177/?type=1&theater
To say in short:
To understand iron profile it is important to understand stages of iron deficiency first.
When iron is deficient , at first the storage iron begins to deplete. That means ferritin (storage form of iron ) begins to deplete. Serum iron remains normal initially.
But when ferritin begins to decrease hepatic macrophages can recognize it and they begin to pump out more and more transferrin into the blood with a hope to gather more iron. So transferrin increases. That results in increase TIBC ( Total Iron Binding Capacity ) . Recall that Transferrin is the measure of TIBC. The more transferrin in the blood the more iron can bind with it. So Total Iron Binding Capacity will increase.
In second stage , storage iron is depleted and serum iron also begins to deplete.
In third stage Normocytic Anaemia develops. The mechanism is - bone marrow is still able to make RBC of proper size and of proper MCH , MCHC and MCV but in reduced number due to iron deficiency.
In last stage iron deficiency is so severe that bonemarrow cannot maintain MCV, MCH, MCHC of RBC and microcytic hypochromic anaemia results.
Hope it is helpful. Thank you for liking my video. My newer videos are shot with better camera. More videos coming soon !
Take care and stay blessed.
*****
thank you doc,, this is a big help in our case study,, thank you for the info.
thnx sir
Thank you for liking my videos. Take care and stay blessed. :)
Please make a video on neoplasia and rbc and wbc disorders
Thank you for your feedback. I already have videos on neoplasia and rbc disorders. Please look into "videos" section of this channel (click "load more" or scroll down if required). This channel has 76 videos on various topics so far. Link:
th-cam.com/users/DrRabiulHaquevideos
Sir please make a video about sideroblastic anaemia.🙏🙏
Amazing I loved it so mmmmmuuuuuuuuchh💗💗💗
Why doesn't acute blood loss cause iron deficiency anaemia ?
Thank you so much 🌸🌸
Thank you for your feedback. Take care and stay safe. Best wishes from Bangladesh. :)
Thank you x200 million times 💪
Thank you for your feedback. Take care and stay safe.
Does iron deficiency anemia have effect on red cell life span.
Thanku sir
Thank you for watching my videos and for your feedback. Take care & stay blessed. :)
Dear doc ,so nice.
Make a good presentation with good pictures like Dr Ajit virkut of India . You are young make a team .and make best of lectures. And remove your older vedios with new lectures .why you are ashamed of dhaka
Tell that iam from Dhaka .be proud of your nation .make a good team and make word best e book . Aashish Dr nagar india gynecologist
Thank you sir for your feedback. Due to copy right issue I did not use images in my old videos. My newer videos have self drawn and computer rendered images. Upcoming videos will have self made 3D rendered animations as I have been learning it for one year (Test animation already used in title of my last video of leukaemoid reaction). Any copy right free image is always welcomed (specimen or histopathological images) that I can use attributing the source or person. I also have plans to start haematology and histopsthology slide sessions in the future. My city and current designation is shown in most of my video titles. I sincerely agree that everyone should be proud of his own nation and I am also proud of mine. Any suggestion and feedback in other videos are always welcomed. Take care and stay blessed. My best wishes for Dr Arjit sir's channel.
My hemoglobin is 3.0. They wanted to give me 3 units of blood. I don't want to take it cause the transfusions make me sick. I take iron pills 2 times a day. Any suggestion for me?
Haemoglobin 3 is a life threatening condition, urgent blood transfusion is needed to correct it quickly, please follow your physician's advice quickly.
Very helpful bt long duration video...
Thank you for your feedback. Take care and stay blessed. :)
Does Vit-C oxidize the Fe3+ to Fe2+ ?
Fe³⁺ it is converted on the surface of the duodenal mucosa at Fe²⁺ ( under the influence of a reductase ) , this being transported to the cells of the duodenal mucosa with the help of a Fe²⁺ - H ⁺ cotransport system
Ralf Schooneveld Vit C also known as ascorbic acid converts oxidized iron fe3+ into reduced form fe2+
Anemia is low oxygen carrying capacity of blood.pl say some thing about this definition also.
what text book are you using?
Hello, I took help of the following Books to make this video.
1. de Gruchy's Clinical Haematology in Medical Practice (5th revised edition).
2. Rapid review Pathology : Edward F Goljan (3rd Edition, South East Asia Region)
3. Robbins and Cortan : Pathologic Basis of Disease (8th Edition)
4. Kaplan Biochemistry Review Book (For Iron Metabolism)
Regarding your second question:
HFE gene products have a role in iron absorption. Our body tries to absorb iron at around 1 mg/ day. 10 % of our dietary intake of iron gets absorbed. When there is mutation in HFE gene , too much iron will be absorbed. ( eg. 2 mg/day , 3 mg/day etc. which will result in iron overload slowly (e.g in 10/20 years). If I want to be more specific HFE gene products helps plasma transferrin to bind with it's mucosal cell transferrin receptor. Then transferrin can be endocytosed inside mucosal cell and take up iron and take it to different tissues via blood. Amount of endocytosed transferrin determines how much mucosal cell iron gets released into plasma and binds to transferrin. That's as far as I know. You can look into Biochemistry Text Books if you need more info. Again, Thank you for liking my videos. My newer videos are shot with better camera. Take care & stay blessed. Best wishes from Bangladesh. :)
I thought Ferroportins kick iron out without the need of transferrin coming in and picking them up. and TfR are only found on cells that need iron, such as RBCs. But I guess you are right since all cells technically need iron including the enterocyte themselves. Let me know if any of what I said is wrong. Thank you for the vid it was great and I hope you continue recording videos. They are really helpful. Best of Luck!!
Love from india....
Thank you for your feedback. Take care and stay safe. Best wishes from Bangladesh. :)
It is pronounced as I -on . The r is silent.
sir, at 25:26 how menopause possible in male acc. to you???
Thank.you.very.much.sir.
Thank you for your feedback. Take care and stay blessed.