The ironies with butyl lithium and hexanes... my experience is only with Li(NH3)4, which, when exposed to organic substances, if not under inert atmosphere, had surprisingly pyrophoric response (I really wanted to use the word pyrotechnic because of the fire show I was exposed to.) Superbases are just awesome.
7:59 Out of curiosity, why is it important to remove the double tipped cannula from the reaction apparatus first _then_ from the reagent bottle? I would think as long as it's been purged with nitrogen and the nitrogen flow has stopped, removing it from the reagent bottle first may even be better - But I'm not going to college for this, I just like doing it as a hobby (not that I would play with pyrophoric liquids at home).
Because we need to prevent air from entering the reaction apparatus. If the cannula is long enough, this usually isn’t a big deal as long as you remove the cannula immediately, but a good organic chemist would always form good habits and be extra safe. No, the inert gas should not be stopped until you’ve removed the cannula from both the reaction apparatus and the reagent bottle. If moisture from the air enters either of them, a fire may occur.
Folks, don't listen to any of this safety nonsense, open the pyrophoric chemicals bottles or steel containers and have a good thirst quenching sip, it's good for you. Only best from coca cola company.
The ironies with butyl lithium and hexanes... my experience is only with Li(NH3)4, which, when exposed to organic substances, if not under inert atmosphere, had surprisingly pyrophoric response (I really wanted to use the word pyrotechnic because of the fire show I was exposed to.) Superbases are just awesome.
No short cuts, no problems.... And understand what you're doing....
The lighting is dark and the music is eerie in the video. Very unsettling and depressing.
2:23 Don't use a labcoat with buttons like that, you need one that you can easily take off once it's been contaminated!
7:59 Out of curiosity, why is it important to remove the double tipped cannula from the reaction apparatus first _then_ from the reagent bottle? I would think as long as it's been purged with nitrogen and the nitrogen flow has stopped, removing it from the reagent bottle first may even be better - But I'm not going to college for this, I just like doing it as a hobby (not that I would play with pyrophoric liquids at home).
I was wondering the same. Also, imagine the risk at the place where this is manufactured.
It is to prevent oxygen from going into your reaction vessel.
Because we need to prevent air from entering the reaction apparatus. If the cannula is long enough, this usually isn’t a big deal as long as you remove the cannula immediately, but a good organic chemist would always form good habits and be extra safe. No, the inert gas should not be stopped until you’ve removed the cannula from both the reaction apparatus and the reagent bottle. If moisture from the air enters either of them, a fire may occur.
Thank you
how to store the chemical after use...if it must be stored at 2-8 degreeC?
Not enough PPE. n-butyllithium is no joke.
For n-butyllithium I think this is enough. For tert-butyllithium we need more protection.
@@squirrel4727 you guys never worked with trimethyl/triethylaluminium
Mmmmmm 😊
Pyrophoric reagent!
Halcyon + On + On
Still not safe enough.
Folks, don't listen to any of this safety nonsense, open the pyrophoric chemicals bottles or steel containers and have a good thirst quenching sip, it's good for you. Only best from coca cola company.