Acid/Base Chemistry in Medicinal Chemistry

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  • เผยแพร่เมื่อ 6 ก.ย. 2024

ความคิดเห็น • 27

  • @BarrySRNA
    @BarrySRNA 7 หลายเดือนก่อน +2

    So how do you determine if a drug is basic or acidic based on pKa?

  • @iloveMjoda
    @iloveMjoda 11 ปีที่แล้ว +1

    Oh thank you for replaying ! One question if you have time :D ! this has a lil to do with acids and bases which I don't get .... I know what acids and bases are. Acid are that Produce hydrogen ions (H+) when mixed with water and bases Produce hydroxide ions (OH-). My question is what acids and bases really do! are one dangerous than the other ? or cause a stronger reaction like if you put acids or bases to your hair it will change color! that's what I don't really get !

  • @cat875
    @cat875 2 ปีที่แล้ว +1

    awesome video!
    Favor for baby chemistry students like me: can you connect this to the salt form of the drug prior to it dissociating to an acid? I am just confused because the acidic form at this point will be an anion so is ionized, how will this pass through the lipid membrane?
    can you also add why the salt form of the drug is important for its solubility and absorbability?

  • @gotwalsb
    @gotwalsb  11 ปีที่แล้ว

    it just means that the solution has a concentration of hydrogen ions (H+) of 0.0000001 moles of hydrogen ions in one liter of water. That's in the middle of the pH scale, so we call it "neutral", meaning it's BOTH an acid AND a base...amphoteric is the term.

  • @zaman0103
    @zaman0103 11 ปีที่แล้ว +1

    one of the best explanation

  • @Mssugarcane89
    @Mssugarcane89 11 ปีที่แล้ว +2

    You explain everything so clear. Thank you!

    • @gianniellis7721
      @gianniellis7721 3 ปีที่แล้ว

      i realize I am quite off topic but do anybody know of a good site to watch newly released movies online ?

  • @jennifernguyen3554
    @jennifernguyen3554 7 ปีที่แล้ว +1

    your video helped me tremendously. thank you!

  • @iloveMjoda
    @iloveMjoda 11 ปีที่แล้ว

    More back round about acids and bases !

  • @NithinJohnVarghese
    @NithinJohnVarghese 8 ปีที่แล้ว

    Thank you very much.its very helpful to improve Myself.

  • @gotwalsb
    @gotwalsb  11 ปีที่แล้ว

    This podcast assumes that the viewer has taken basic chemistry and knows what acids and bases are. This podcast ONLY talks about acid/base chemistry in drug design. There are plenty of other resources on introductory acid-base chemistry!

  • @VentusK
    @VentusK 8 ปีที่แล้ว

    beautiful podcast

  • @mohammedalmabrouk3315
    @mohammedalmabrouk3315 11 ปีที่แล้ว

    i'm postgraduate student & i wanna to study pharmacology so i need some help if u can about the subjects that related to postgraduate pharmacology M.D & PhD....

  • @raudoniguzikai
    @raudoniguzikai 10 ปีที่แล้ว

    Very useful. Thank you!!! :)

  • @kaushiktrivedi351
    @kaushiktrivedi351 6 ปีที่แล้ว

    Very useful

  • @iloveMjoda
    @iloveMjoda 11 ปีที่แล้ว

    I know having a ph of 7 means its neutral meaning it has no effect whats so ever ! am correct ? or wrong ?

  • @dorctormido5104
    @dorctormido5104 8 ปีที่แล้ว

    Thanks alot.

  • @sonicbouy
    @sonicbouy 8 ปีที่แล้ว

    very helpful

  • @Thu2za
    @Thu2za 9 ปีที่แล้ว

    so helpfull thanks a lot :)

  • @NextgenBeast93
    @NextgenBeast93 6 ปีที่แล้ว

    He was talking too much and going too fast people can hold no more than 7-9 things in their memory at once.

    • @cat875
      @cat875 2 ปีที่แล้ว

      you can adjust the speed of the video

  • @doctorfaranali7239
    @doctorfaranali7239 8 ปีที่แล้ว

    Bakwas

    • @zenab9976
      @zenab9976 7 ปีที่แล้ว +1

      What is the mean of bakwas

    • @JaiSinghDhaliwal
      @JaiSinghDhaliwal 6 วันที่ผ่านมา

      ​@@zenab9976It means Rubbish