Oncogenetics - Mechanism of Cancer (tumor suppressor genes and oncogenes)

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  • เผยแพร่เมื่อ 23 ก.ค. 2024
  • Where do I get my information from: armandoh.org/resource
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ความคิดเห็น • 514

  • @MukeshMorwall
    @MukeshMorwall 3 ปีที่แล้ว +88

    The Schools and Universities Need teachers like you .

    • @Chkoutmyvideos
      @Chkoutmyvideos 2 หลายเดือนก่อน

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  • @alsubaiea9869
    @alsubaiea9869 5 ปีที่แล้ว +314

    WOW! Incredible how you are able to make this complicated topic so much easier. Thanks a lot, you are a HERO

    • @angelmihaylov3681
      @angelmihaylov3681 4 ปีที่แล้ว +11

      The student books use unnecessary complicated terminology.

    • @asherfrancisco7417
      @asherfrancisco7417 2 ปีที่แล้ว

      I dont mean to be so off topic but does any of you know a trick to log back into an Instagram account?
      I somehow lost the account password. I would love any help you can offer me!

    • @zakkymiftahurrahman1665
      @zakkymiftahurrahman1665 2 ปีที่แล้ว

      @@asherfrancisco7417 begone, BOT

    • @Chkoutmyvideos
      @Chkoutmyvideos 2 หลายเดือนก่อน

      th-cam.com/video/5jGFVhpB030/w-d-xo.htmlsi=HpiqdN3JEJsBNXWI

  • @virnan
    @virnan 4 ปีที่แล้ว +38

    Armando, you are gifted in many areas but one of them is your ability in simplifying complex subjects.

  • @charleexiong1601
    @charleexiong1601 5 ปีที่แล้ว +71

    It makes me so happy when I want to understand something, so I look to youtube for an explanation and Armando has covered it. He is always my first choice. Such clarity he presents to the minds of his audience

    • @Chkoutmyvideos
      @Chkoutmyvideos 2 หลายเดือนก่อน

      th-cam.com/video/5jGFVhpB030/w-d-xo.htmlsi=HpiqdN3JEJsBNXWI

  • @bellal4776
    @bellal4776 3 ปีที่แล้ว +3

    Got my cell pathology exam tomorrow and this video is brilliant, just what I needed. Thank you so much for your help!

  • @ranushavelavan7598
    @ranushavelavan7598 4 ปีที่แล้ว +4

    Amazing and thorough explanation with descriptive visuals to help us grasp this somewhat challenging topic. Thank you very much Mr. Hasudungan, looking forward to more videos like in this :)

  • @mohammedahmedjalloh531
    @mohammedahmedjalloh531 4 ปีที่แล้ว +4

    Before this Video ENDS with the lack of words to describe your lecture.. I just want to say "I LOVE YOU"

  • @mariaorsic9763
    @mariaorsic9763 2 ปีที่แล้ว +4

    Astoundingly concise! More learning in 15 minutes than endless hours with textbook. I will purchase or donate!!!

  • @asifsiddique4783
    @asifsiddique4783 3 ปีที่แล้ว +2

    I pray and hope your lectures help a lot more other dummies like me. Appreciate it, man! Amazing lecture.

  • @Prof.pavanjadhav
    @Prof.pavanjadhav 5 ปีที่แล้ว +32

    Yes.. It helped as it always does. Thank you so much. Love from India 🇮🇳

  • @ayaibrahim6227
    @ayaibrahim6227 2 ปีที่แล้ว +4

    im gonna do my AS bio mcq paper in 2 weeks and im absolutely so thankful for having these videos as revision, especially in a different way of teaching than my biology teacher, god bless him. thank you so much i'll never forget this

    • @Chkoutmyvideos
      @Chkoutmyvideos 2 หลายเดือนก่อน

      th-cam.com/video/5jGFVhpB030/w-d-xo.htmlsi=HpiqdN3JEJsBNXWI

  • @maheshbabu552
    @maheshbabu552 2 ปีที่แล้ว +1

    Every School,College, University should have a teacher like you!! Tq sir..

  • @freeradicalpanda
    @freeradicalpanda 3 ปีที่แล้ว +1

    So much clearer when presented like this. Great work! Please keep posting.

  • @erikaluna6414
    @erikaluna6414 3 ปีที่แล้ว +2

    I hope you continue making these videos, they are an insane amount of help! thank you for your time and dedication :)

  • @thehermit5886
    @thehermit5886 ปีที่แล้ว +1

    Your illustrations are amazing and make it so easy to understand. Thank you!

  • @yankee7238
    @yankee7238 8 หลายเดือนก่อน

    So neat, aesthetically pleasing illustrations, clear and concise explanation. Much appreciated love

  • @tonydistefano6464
    @tonydistefano6464 5 ปีที่แล้ว +1

    Thank you for this video. There is so much going on in every step of the cancer process. This has help me understand the complexity of tumor growth

  • @ELPaso1990TX
    @ELPaso1990TX 2 ปีที่แล้ว +10

    Awesome explanation! I’ve not done molecular biology for 20 years and your video is so easy to understand and feels like only yesterday I was studying molecular biology. Would so love to do a masters degree or PhD in oncology but it was probably too long ago since my degree.

  • @justonegoodvideo
    @justonegoodvideo 3 ปีที่แล้ว +2

    This was a really helpful foundation to understand before studying specific cancers!
    Thanks, appreciate it a lot!

  • @devavarrshinie16
    @devavarrshinie16 10 หลายเดือนก่อน

    my lecture taught me for 2 hours and you taught me just in 11 mins and i understood everything.Thank you🙏

  • @hassansharaya
    @hassansharaya 4 ปีที่แล้ว +2

    I loved your video, I really struggled to understand the mechanism of cancer formation. After watching this video I feel I have a strong foundation to further learn about cancers

  • @erikmuller9270
    @erikmuller9270 3 ปีที่แล้ว +1

    Man, you're amazing! Thank you so much. I was hanging over my text book all day, trying to understand this and finally you saved me. I'd subscribe like 8 times, if I could. Wishing you all the best and stay healthy my friend.
    Greetings from Germany.

  • @user-lr1if9dm7b
    @user-lr1if9dm7b 19 วันที่ผ่านมา

    This is fantastic. I’m studying for my OCN certification and having visual imagery really helps. Subscribed!!!

  • @ritapaulchoudhury623
    @ritapaulchoudhury623 หลายเดือนก่อน

    I am searching such a vdo for a long time to better clearification and now i get this !😍
    The way u r explaining in a well manner ..step by step ...😍
    Appreciating !👏
    Thank you sir ,thank you ♥️

  • @pastorpeterkim
    @pastorpeterkim 3 ปีที่แล้ว +1

    best of best lectures. You have such an excellent logical smooth way of explanining a thing.

  • @paml3742
    @paml3742 4 ปีที่แล้ว +1

    You’re genuinely the best teacher

  • @itg1262
    @itg1262 3 ปีที่แล้ว +1

    You are excellent in articulating the topic. Nicely done

  • @joanmacharia8730
    @joanmacharia8730 3 ปีที่แล้ว +1

    these things never made sense till you came along.. thank you

  • @a1icecold
    @a1icecold 6 ปีที่แล้ว +78

    One thing missing from this video is the one hit two-hit mechanism of oncogenes and ts genes. We have two copies of all genes, for cancer/neoplasia to occur through oncogenes only one of two gene copies need activating mutations whereas both copies of the tumor suppressor gene to inactivate/mutate before neoplasia can occur.

    • @edthoreum7625
      @edthoreum7625 5 ปีที่แล้ว

      ALSO,,, how can the transcription factor m-myc which plays aN important role
      in iPSC also become an oncogene? (5:20)

    • @debabratalaik9296
      @debabratalaik9296 4 ปีที่แล้ว

      @@DNielsen113 elaborate plz

    • @arsalanarif4287
      @arsalanarif4287 4 ปีที่แล้ว +2

      Debabrata Laik he is right because tumor suppressor gene if one become mutant so second gene from maternal or paternal works and that is able for control cell cycle so both genes of tumor suppressor should become mutant for a cell to become neoplastic

    • @natashasalmelin720
      @natashasalmelin720 3 ปีที่แล้ว +8

      @@edthoreum7625 This is one year late, but I'll still answer. Myc is a proto-oncogene, meaning that a normal Myc will not cause cancer. Only when Myc is mutated so it is abnormally overexpressed will it be an onogene and cause cancer. A normal Myc, like in the iPS cells are important for the reasons mentioned in the video (growt & survival). In fact Myc is very important during development and cannot be knocked down or removed, because of its regulatory mechanisms of growth and survival. We wouldn't have genes that causes cancer, if it wouldn't be necessary. Hope this helps and here is a link of videos that go into more detail about cancer evolution etc: th-cam.com/video/sa5X97OQLHs/w-d-xo.html

    • @user-kp5yi7hb4z
      @user-kp5yi7hb4z 3 ปีที่แล้ว +1

      Where are you from bro?

  • @we_are_made_of_love6784
    @we_are_made_of_love6784 2 ปีที่แล้ว

    God bless the genius that was able to talk so smoothly, clearly and incredibly deep and yet specific enough to a simple and clear understanding of oncogenes. thanks!

  • @lisatryemka9775
    @lisatryemka9775 3 ปีที่แล้ว

    Thank you! Your diagrams were very creative and flowed well with the subjects discussed.

  • @chelseahaas1467
    @chelseahaas1467 4 ปีที่แล้ว +10

    This was an awesome and well explained video! Thank you for being such a great teacher on a really complex topic! I would love to have that picture to reference when studying. Are you able to post a link of the picture you drew?

  • @Melzare
    @Melzare 6 ปีที่แล้ว +3

    Wow!! What timing. I have a test on this Thursday and was about to search for videos.

    • @WaqarAhmed-ec5xp
      @WaqarAhmed-ec5xp 6 ปีที่แล้ว +1

      Melzare goodluck mate

    • @soumyasumanvlogs8272
      @soumyasumanvlogs8272 6 ปีที่แล้ว +1

      Melzareth-cam.com/video/boKtAsGbwY8/w-d-xo.html plz subscribe my channel on TH-cam. For more videos

  • @asramohammadi9339
    @asramohammadi9339 2 ปีที่แล้ว

    How beautiful. ❤️🥺 Thank you. Such a sweet explanation with such extraordinary flowcharts

  • @chandrakiransahu6600
    @chandrakiransahu6600 11 หลายเดือนก่อน

    Omg I was so tensed that how I would even understand this earlier but now you've simply made it so crystal clear

  • @HauntyMonty
    @HauntyMonty 3 ปีที่แล้ว +8

    6:15 oncogenes: ras gene , myc gene
    9:12 tumour suppressor gene: p53, brca 1/2 ,apc

  • @thenightdances21
    @thenightdances21 5 หลายเดือนก่อน

    This video is VERY important for the MCAT biology & biochem section! RAS and MYC comes up frequently on the bio/biochem passages!! Thank you SO much for explaining this clearly!!

  • @nathansherman5640
    @nathansherman5640 3 ปีที่แล้ว +1

    Thank you, this pretty much perfectly sums up the first 3 chapters of my oncology textbook. This makes much more sense in video format than text

  • @futureDrNLB
    @futureDrNLB 4 ปีที่แล้ว

    I wish I discovered when I was taking cancer biology this would have lowered my learning covering significantly. I will share your youtube with friends who are currently taking cancer biology.

  • @nishadr.7637
    @nishadr.7637 2 ปีที่แล้ว +1

    props to you for explaining it better than my bio teacher ever could

  • @LovetheLoveliness
    @LovetheLoveliness 5 ปีที่แล้ว +3

    very helpful and neatly organized! love your videos :)

  • @mrsdiggory3211
    @mrsdiggory3211 5 ปีที่แล้ว +3

    Thank youuu! I have an exam soon and this really clears everything up! x

  • @shambhavitrivedi4550
    @shambhavitrivedi4550 6 ปีที่แล้ว +2

    Amazing as always!!😍
    Thankyou !

  • @NhanLe-jt6gh
    @NhanLe-jt6gh 4 หลายเดือนก่อน

    You're so great !! I've struggled this topics for so long and can't get it

  • @angelaedhere639
    @angelaedhere639 4 ปีที่แล้ว +1

    Thank you so much! You provided a lot of clarity on such a complicated topic.
    God bless you!

  • @amandajones6160
    @amandajones6160 ปีที่แล้ว

    I would love to have your drawing from the end of the video. This has helped me so much!

  • @gulsumbicer299
    @gulsumbicer299 2 ปีที่แล้ว

    it is the most beneficial video ı have ever watched about this topic on youtube. Reaaly thank you for making this video.

  • @tiujasmine1601
    @tiujasmine1601 2 ปีที่แล้ว +1

    Thank you for explaining hard topics in a very simple way!

  • @eloramichelle7948
    @eloramichelle7948 9 หลายเดือนก่อน

    Man I’ve been in patho physiology lost and you my friend just explained oncogenes like a pro

  • @Jindy2
    @Jindy2 5 ปีที่แล้ว +1

    Clear, concise and easy to understand. Just great. Many thanks.

  • @dr.sammasud7401
    @dr.sammasud7401 2 ปีที่แล้ว

    The video is very helpful, easy to understand, to the point and full of essential information. So so helpful to understand complex topic. Thanks

  • @laughhubke.9699
    @laughhubke.9699 3 ปีที่แล้ว

    Wow! Finally i got someone who could explain the complex topic in an undestandible way,, thanks👍

  • @svan1778
    @svan1778 3 หลายเดือนก่อน

    This is great! Currently watching this at 4:30 am before my 9:00 am bio exam!

  • @sharonsia1064
    @sharonsia1064 2 ปีที่แล้ว

    so much clearer and marked in mind with your flow diagrams. TQ !!!

  • @samuelchinda-sb9zw
    @samuelchinda-sb9zw หลายเดือนก่อน

    Thank you immensely for this video.... All the scales have been unraveled 🎉❤❤

  • @nabilamutiarani6048
    @nabilamutiarani6048 3 ปีที่แล้ว

    thank you so much please keep making another video like this, you really help me

  • @mahdiomidvar564
    @mahdiomidvar564 3 ปีที่แล้ว +1

    armando i pass the exam of pathology just because of great explanations .... i really thank you from the bottom of my heart.... .

  • @nonamefound9296
    @nonamefound9296 2 ปีที่แล้ว +1

    You just saved my life, thank you sooo much!

  • @user-mk9bv7nn5g
    @user-mk9bv7nn5g 4 หลายเดือนก่อน

    Brilliant explanation !! The way you broke the topic and made it interesting and easy to understand, sir hats off to you.

  • @jovana7366
    @jovana7366 4 ปีที่แล้ว +1

    Good job! Very precisely described and easy to follow.

  • @monaoconnell5650
    @monaoconnell5650 2 ปีที่แล้ว

    Outstanding! Hope you com back!

  • @user-dc8sk4em8b
    @user-dc8sk4em8b 2 หลายเดือนก่อน

    Excellent explanation to brush up genetics quickly for both undergraduate and postgraduate students as well as science enthusiasts 👍👍 brilliant work ✅✅😊

  • @stephenleyva9672
    @stephenleyva9672 ปีที่แล้ว

    great video, fantastic drawings

  • @berfinkizi5831
    @berfinkizi5831 6 ปีที่แล้ว +17

    You are amazing teacher.. İ wish i was your student.

  • @sultanmahmood9634
    @sultanmahmood9634 ปีที่แล้ว

    thanks a lot, direct, precise & very easy way to demonstrate

  • @noumidiakarabila9514
    @noumidiakarabila9514 2 ปีที่แล้ว +1

    i became more happy😊 and interested in a subject every time i watch your videos .
    thank you so much

  • @iman_ktb
    @iman_ktb 2 ปีที่แล้ว

    Thank you so much.. i didn't have much time to read pdfs..so this was really helpful

  • @asiyaijaz2835
    @asiyaijaz2835 5 ปีที่แล้ว +1

    having no words sir... outstanding❤

  • @mohammedkaleemkhan9585
    @mohammedkaleemkhan9585 4 ปีที่แล้ว

    Fabulous explanation Dr

  • @sunil7549
    @sunil7549 6 หลายเดือนก่อน +1

    Ohhh my god!!!!!
    Sir , you're damn good , day after tomorrow is note submission of cancer biology and if the notes are not submitted on time my teacher will not allow me to attend the class and somehow you've saved me from that, by clearing the concepts through linking various things , thank you once again sir !!!
    From India 🇮🇳🇮🇳🇮🇳

  • @bts_rollercosterlifepurplearmy
    @bts_rollercosterlifepurplearmy ปีที่แล้ว

    Your presentation is awesome 👍👍👍

  • @amancharan8184
    @amancharan8184 2 ปีที่แล้ว

    This video wad so helpful for me. Thank you soo much your video have cleared all the doubts about Oncogenetics.

  • @hariharababu3929
    @hariharababu3929 4 ปีที่แล้ว +2

    Thank you so much for your wonderful presentation and lecture.. it really makes me to understand what it is and how it is??

  • @divasgupta5054
    @divasgupta5054 2 ปีที่แล้ว

    amazing..!!! you made this complicated topic
    so easy to understand .... 🤩

  • @hibaalzain5319
    @hibaalzain5319 3 ปีที่แล้ว

    The most incredible video.... Thank you

  • @lillaermy7987
    @lillaermy7987 6 ปีที่แล้ว +1

    OMG ! Love it ! You are such an angel !!!

  • @gagazunicorn388
    @gagazunicorn388 3 ปีที่แล้ว

    SO CLEAR!!! thank you. liked and subscribed

  • @theincrediblemd9761
    @theincrediblemd9761 2 ปีที่แล้ว

    Absolutely AMAZING !!! 👏 I wanted him to go on and on about BRCA 1, BRCA 2, APC

  • @peaceyya2181
    @peaceyya2181 5 หลายเดือนก่อน

    thank you for imparting this knowledge ❤️❤️I now understand the molecular basis of cancer

  • @sabahalezaireg9023
    @sabahalezaireg9023 3 ปีที่แล้ว

    You are absolutely amazing!

  • @shadeedsalem
    @shadeedsalem 3 ปีที่แล้ว +1

    Excellent video!!

  • @drvinukrishnan3169
    @drvinukrishnan3169 4 ปีที่แล้ว

    awesome....
    excellent presentation with superb drawings making a complicated subject into extra fluid style...
    great sir

  • @norj25
    @norj25 ปีที่แล้ว

    i loved how he simplifed this very complex concept is!!!

  • @eriquelukong2149
    @eriquelukong2149 3 ปีที่แล้ว

    Gem caliber delivery. Well done. Thank you very much

  • @saipien2868
    @saipien2868 3 ปีที่แล้ว

    This video was very helpful. Thanks so much.

  • @entisaralhaddar4005
    @entisaralhaddar4005 3 ปีที่แล้ว

    Thank you so much! You make the complicated look so simple

  • @drwasim516
    @drwasim516 ปีที่แล้ว

    Super explanation dear professor

  • @paulschult7161
    @paulschult7161 3 ปีที่แล้ว

    This is perfect, thank you so much. Your explanation rlly helped me a lot for my exam 💯🙌🏼🙌🏼🙌🏼

  • @brittophone6219
    @brittophone6219 3 ปีที่แล้ว

    You are an artist!! Thx a lot ❤️

  • @fatemahalshammary3352
    @fatemahalshammary3352 2 ปีที่แล้ว

    Thank you!!! This video was really helpful!🤍🤍🤍

  • @ramachandraiahgosu758
    @ramachandraiahgosu758 2 ปีที่แล้ว

    Thank you. Very educative and simplified to understand the complex subject

  • @marisollopez3475
    @marisollopez3475 4 ปีที่แล้ว

    Wonderful explanation!!

  • @biologyexpert586
    @biologyexpert586 3 ปีที่แล้ว +1

    Teaching method is really very good

  • @inesochmann3263
    @inesochmann3263 3 ปีที่แล้ว

    Thank you so much for your fantastic work! now I finally understand the connections between p53 and p21 👍

  • @selsabilblh3609
    @selsabilblh3609 3 ปีที่แล้ว

    You are a legend...THANK YOU it helped me a lot ! Respect from Algeria

  • @amaymay2158
    @amaymay2158 ปีที่แล้ว

    Thank you so much for this video! My final exam is tomorrow and this helped me alot! ❤

  • @Myfitzn
    @Myfitzn 6 ปีที่แล้ว +2

    i wanted to appreciate for all of your videos all of them made me understanding better and get a overview some of them like biochemistry playlist saved my life for final exam thank you armando

  • @LeenaLittleElf
    @LeenaLittleElf 2 หลายเดือนก่อน

    Such a great video. Thank you.

  • @HIEU514
    @HIEU514 3 ปีที่แล้ว

    Fascinating video. Thank you a lot!

  • @celebritytrendtv2183
    @celebritytrendtv2183 2 ปีที่แล้ว

    Everytime I watch this video, I wish I could give it another like........ So comprehensive