colony PCR

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  • เผยแพร่เมื่อ 19 พ.ย. 2024

ความคิดเห็น • 44

  • @toasterspoon5000
    @toasterspoon5000 3 ปีที่แล้ว +6

    Great illustration and precise 3 min video! Very helpful thank you from Seattle, Washington!

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 ปีที่แล้ว +1

      Glad to hear that my content helped you. Please share my channel link with your friends and help me to reach big audience. Lots of love from India.

  • @mrdoodoo2935
    @mrdoodoo2935 2 ปีที่แล้ว +5

    You are like a god you really save my day when i dont understand my lectures. Thank you so much ! ❤️

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 ปีที่แล้ว

      Really glad to know it was useful. Please follow my instagram page and facebook page. Please share my youtube channel link with your friends and help me to reach big audiance
      I'm on facebook & Instagram as @animatedbiologywitharpan. Install the app to download notes and flash cards. instagram.com/invites/contact/?i=1p41h314q3fv8&
      You can support the channel by clicking on the super like icon below the video ( a heart sign with $ in it ) . You can support using paytm/ phone pe/ gPay / paypal. Your small contribution means a lot for me

  • @soumyasahaisaxena3761
    @soumyasahaisaxena3761 2 ปีที่แล้ว +1

    Thankyou soo much for this wonderful video

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 ปีที่แล้ว

      Really glad to know it was useful. Please follow my instagram page and facebook page. Please share my youtube channel link with your friends and help me to reach big audiance
      I'm on Instagram as @animatedbiologywitharpan. Install the app to follow my photos and videos. instagram.com/invites/contact/?i=1p41h314q3fv8&

  • @mal.v
    @mal.v 3 ปีที่แล้ว +2

    Great explanation, thanks!

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 ปีที่แล้ว

      Please share my channel link with your friends and help me to reach big audience

  • @balaselvakumars
    @balaselvakumars 2 ปีที่แล้ว +1

    Thankyou.. it'll be useful for my seminar

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 ปีที่แล้ว +1

      Really glad to know it was useful. Please follow my instagram page and facebook page. Please share my youtube channel link with your friends and help me to reach big audiance
      I'm on facebook & Instagram as @animatedbiologywitharpan. Install the app to download notes and flash cards. instagram.com/invites/contact/?i=1p41h314q3fv8&
      You can support the channel by clicking on the super like icon below the video ( a heart sign with $ in it ) . You can support using paytm/ phone pe/ gPay / paypal. Your small contribution means a lot for me

    • @balaselvakumars
      @balaselvakumars 2 ปีที่แล้ว

      @@animatedbiologywitharpan sure 💙

  • @mzztter08official
    @mzztter08official 2 ปีที่แล้ว +1

    Thanks for your content

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 ปีที่แล้ว

      Really glad to know it was useful. Please follow my instagram page and facebook page. Please share my youtube channel link with your friends and help me to reach big audiance
      I'm on facebook & Instagram as @animatedbiologywitharpan. Install the app to download notes and flash cards. instagram.com/invites/contact/?i=1p41h314q3fv8&
      You can support the channel by clicking on the super like icon below the video ( a heart sign with $ in it ) . You can support using paytm/ phone pe/ gPay / paypal. Your small contribution means a lot for me

  • @nezaralfaya5211
    @nezaralfaya5211 2 ปีที่แล้ว +1

    Thank you so much for your explanation.
    I can’t see any colony in my plate after transformation. Can you please give me any suggestions? 🌹🌹

  • @abdullahisaniabubakar6673
    @abdullahisaniabubakar6673 8 หลายเดือนก่อน +1

    Nice video

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  8 หลายเดือนก่อน

      Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

  • @quickbiology5159
    @quickbiology5159 9 หลายเดือนก่อน

    Can you pls make a video on agro agrobacterium freeze thaw method transformation

  • @DoctorFabuloso
    @DoctorFabuloso 3 ปีที่แล้ว +1

    Hope i got that right. So we can use the colony for the pcr as it is without purification, because the impurities from the rest of the bacteria exist only in minute amounts compared to our repeatedly duplicated construct?

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 ปีที่แล้ว +2

      Ya sometimes having a crude extract is good enough.....colony pcr is very robust and inexpensive method because you don't really have to purify all the dna from a colony

    • @DoctorFabuloso
      @DoctorFabuloso 3 ปีที่แล้ว

      @@animatedbiologywitharpan Alright, thanks a lot! ^^

  • @fauzilazhiim1476
    @fauzilazhiim1476 2 ปีที่แล้ว +1

    so, the difference between colony pcr and normal pcr is you don't need to isolated the dna from our target right?

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 ปีที่แล้ว +1

      Yes you are right.

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 ปีที่แล้ว +1

      Really glad to know it was useful. Please follow my instagram page and facebook page. Please share my youtube channel link with your friends and help me to reach big audiance
      I'm on facebook & Instagram as @animatedbiologywitharpan. Install the app to download notes and flash cards. instagram.com/invites/contact/?i=1p41h314q3fv8&
      You can support the channel by clicking on the super like icon below the video ( a heart sign with $ in it ) . You can support using paytm/ phone pe/ gPay / paypal. Your small contribution means a lot for me

  • @javierfernandez3342
    @javierfernandez3342 2 ปีที่แล้ว +1

    Do You recomend doing this, in the case of cloning a fragment for a real time pcr? Thx

  • @FTMWarlord
    @FTMWarlord 2 ปีที่แล้ว +1

    Question regarding cases where colonies are small, such as when growing in low temp conditions. Can you dilute the colony in water or broth, then use some for PCR and some for overnight culturing?

  • @NekoTonegawa
    @NekoTonegawa 2 ปีที่แล้ว +1

    I normally do this by picking the colony, wash the tip in 50uL of water, then boil it 3 min, and centrifuge it. Then I use the remaining water in the PCR reaction. Can you do this without the boiling/centrifuge step?

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 ปีที่แล้ว +2

      Individual transformants can either be lysed in water with a short heating step or added directly to the PCR reaction and lysed during the initial heating step ( when the temperature reach 95 degree celcius).

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 ปีที่แล้ว +1

      If you find my channel useful please support the channel by clicking on the super like icon below the video ( a heart sign with $ in it ) . You can support using paytm/ phone pe/ gPay / paypal. Your small contribution means a lot for me

  • @user-el7ht6wc2g
    @user-el7ht6wc2g 2 ปีที่แล้ว +1

    How did you make master mix?

  • @cartikey4687
    @cartikey4687 3 ปีที่แล้ว +1

    Trademilling or steady state kya alag alag process hota hai? In dono process mai kya difference hota hai

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 ปีที่แล้ว

      Dynamic instability occurs when the microtubule assembles and disassembles at one end only, while treadmilling occurs when one end polymerizes while the other end disassembles. ... This is due to the fact that within a living cell, many microtubules are tightly anchored at one end of the filament. Moreover treadmilling phenomenon is rare in cells

    • @cartikey4687
      @cartikey4687 3 ปีที่แล้ว +1

      @@animatedbiologywitharpan thanku so so much for this information, no one explained like this❤️❤️❤️❤️❤️❤️

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 ปีที่แล้ว +2

      @@cartikey4687 share with your friends and help me to reach out to big audience.

  • @TALKyLIKEENGLISH
    @TALKyLIKEENGLISH ปีที่แล้ว

    What primers are used in this experiment?

    • @MrEriya
      @MrEriya 6 หลายเดือนก่อน

      Primers will depend on your plasmid construct and depend on which region do u want to amplify

  • @tip_icin_yks
    @tip_icin_yks 3 ปีที่แล้ว +1

    at 1:55 , do i have to use template dna or not ? please i need an answer :'(

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 ปีที่แล้ว +1

      The template DNA would come from bacterial colony hence no need of purification of DNA from these colonies.

    • @tip_icin_yks
      @tip_icin_yks 3 ปีที่แล้ว

      @@animatedbiologywitharpan so i dont need to use dna while preparing mastermix after selecting bacteria colonies, right?

    • @tip_icin_yks
      @tip_icin_yks 3 ปีที่แล้ว

      @@animatedbiologywitharpan i get confused :')