I had a cac score of 1188 at age 68, and every day I thought: this will be the day that I die. It’s been 10 years now and so far so good, but today isn’t over yet.
Prompted by "Outlive" I asked my cardiologist about having a calcium scan, which he agreed "couldn't hurt". The resultant score, for this 74 yr old, habitual exerciser and sensible eater was, surprisingly 5000+!!!!!! After a nuclear stress test came back: "normal blood flow" the medical response was to change the brand/formula of the statin I've been taking (10mg/day)....and that's IT! I gather, medical science has no response/no treatment for my particular condition than to throw their collective hands up and say,...."Well ya never know! Have a nice day!" Your thoughts?
My brother who was 64, passed away of bladder cancer a few years ago. He was a nurse and was very aware of metabolic syndrome, etc.. He was also aware of his heart and our father's history of coronary heart disease. My dad died at 64 as well. Both he and my brother were diabetic, and my brother had high blood pressure. He did take medication over the years, off and on. His calcium score (he wanted his cardiologist to check that due to family history) was 0. In the end, he was metabolically compromised and his overall "health" was not that great. Cancer, not heart disease, got him in the end. It is interesting to see how each individual can have various indicators of longevity, but ultimately, we "don't know what we don't know".
Hi Peter , Dr Malcolm Kendricks latest book "The clot thickens" gives a more plausible hypothesis to CVD causation than just APoB particle count and infact does a great job of debunking this myth. Would be amazing if you and Alan could take a look into this , even better interview Malcolm so we can actually get to the truth of what is happening. I would love to hear your rebuttal to his hypothesis , so far he's just been ignored. Look forward to your reply.
Scary what they said about anyone under 50 having a speck of calcium. I had a scare last year and eventually at follow up a year later the cardiologist told me I didn’t need to make any more appointments. So over the last year I’ve made massive changes and improved my numbers and lost weight. My lipids were always very low hdl and high(ish) ldl. Apob was of course never checked until recently at my request and it came back 85. Despite my doctor saying I had no need for more cardio workups I requested a cac score anyways. It came back at 138. All but five of that in the LAD. A huge surprise to say the least. I was told to keep doing what I am doing regarding diet and exercise and prescribed a statin which I am hesitant to take. I have a second opinion appointment coming up soon. I am a 46 year old male, non-diabetic and my last lipids were hdl 56 (a year ago was 20), ldl 126, apob 85, and Lp(a) 15, triglycerides 50. Scary and frustrating to say the least.
That's because soft plaque, which is not identified by a regular heart CT scan so does not show up in a CAC score, is the problem, not calcified hard plaque.
Had a cac 2 yrs ago at 67. To my horror it was 1240.. the radiologist stopped further testing and advised a cardiologist appointment immediately. After extensive testing sonagram/stress etc. The cardiologist called me and said the tests showed my arteries were clear and calcium manifested either on the outside or maybe within the artery walls..I work out intensely with weights and some cardio and the tests showed I'm in exceptional condition.i am confused.. Did I damage my coronary arteries with too intense exercise?
Initially when inquiring about my tests the cardiologist repeatedly asked about chest pain cramps breathlessness when exercising? I told him never..after extensive stress tests with injected dye, a sonagram,, he found there was either calcium manifested on the outside of my arteries or in the epithelial cells..but no build up or blockage and he cleared me to exercise.. I asked him what the hell caused it and he frankly couldn't say.. maybe some type of inflammation as the technician performing sonogram asked if i ever contracted a weird virus..there is some data suggesting very intense exertion has caused this kind of issue on some athletes.
My calcium score is 10. I am 53. What should I do?
3 ปีที่แล้ว +1
If Peter acknowledges that there are people of old age with high apo b and zero calcium score, that means either that they had low apo b all their life, or that apo b by itself doesn't cause atherosclerosis. If the latter is the case, then there's no reason to try to lower young people's apo b - which even if helped, isn't without cost.
I am completely uneducated in biochemistry but how in the fuck can apoB be causal if there are so many people with astoundingly high ldl/apob that do not have any significant plaque it just doesnt make any sense. i think they clearly do not understand this
"If Peter acknowledges that there are people of old age who smoke and with no lung cancer, that means either that they never smoked, or that smoking doesn't cause lung cancer. If the latter is the case, then there's no reason to try to not smoke - which even if helped, isn't without cost of enjoyment." A causal relationship does not guarantee the outcome. Not all smokers get lung cancer.
6 หลายเดือนก่อน
@@ladagspa2008 Cancer and atherosclerosis aren't comparable, you can compare cancer with heart attacks though. You either have cancer or heart attack, or you don't. Atherosclerosis is gradual, if Apo B causes it, you can't possibly have zero calcium score and high Apo B.
You have an abysmal understanding of causality. Presence of the causal factor doesn't guarantee the effect. It only increases the probability of effect occurring, doesn't make the probability 100%. People who have genes protective against plaques will not get plaques in spite of high ApoB. But we know that its ApoB/LDLc which is literally found in the plaques upon biopsy.
6 หลายเดือนก่อน
@@ladagspa2008 You're contradicting yourself - in your own hypothesis that some genes might be protective from atherosclerosis, for the person who has these genes Apo B doesn't cause atherosclerosis. If you find wood in the fire, it doesn't follow that wood causes fire. It might be necessary, but not a sufficient factor.
I had a cac score of 1188 at age 68, and every day I thought: this will be the day that I die. It’s been 10 years now and so far so good, but today isn’t over yet.
Please check out the work of dr. Ford Brewer he has an excellent TH-cam channel. Your high calcium score is not a death sentence
Are you taking a statin?
I feel the same way. It’s 700. Mine
Well it was nice knowing you both-- just kidding
@@tomdineen7 13 years now.
Prompted by "Outlive" I asked my cardiologist about having a calcium scan, which he agreed "couldn't hurt".
The resultant score, for this 74 yr old, habitual exerciser and sensible eater was, surprisingly 5000+!!!!!!
After a nuclear stress test came back: "normal blood flow" the medical response was to change the brand/formula of the statin I've been taking (10mg/day)....and that's IT!
I gather, medical science has no response/no treatment for my particular condition than to throw their collective hands up and say,...."Well ya never know! Have a nice day!"
Your thoughts?
My brother who was 64, passed away of bladder cancer a few years ago. He was a nurse and was very aware of metabolic syndrome, etc.. He was also aware of his heart and our father's history of coronary heart disease. My dad died at 64 as well. Both he and my brother were diabetic, and my brother had high blood pressure. He did take medication over the years, off and on. His calcium score (he wanted his cardiologist to check that due to family history) was 0. In the end, he was metabolically compromised and his overall "health" was not that great. Cancer, not heart disease, got him in the end. It is interesting to see how each individual can have various indicators of longevity, but ultimately, we "don't know what we don't know".
Hi Peter , Dr Malcolm Kendricks latest book "The clot thickens" gives a more plausible hypothesis to CVD causation than just APoB particle count and infact does a great job of debunking this myth. Would be amazing if you and Alan could take a look into this , even better interview Malcolm so we can actually get to the truth of what is happening. I would love to hear your rebuttal to his hypothesis , so far he's just been ignored. Look forward to your reply.
They wont reply cos Dr K is anti establishment
Scary what they said about anyone under 50 having a speck of calcium. I had a scare last year and eventually at follow up a year later the cardiologist told me I didn’t need to make any more appointments. So over the last year I’ve made massive changes and improved my numbers and lost weight. My lipids were always very low hdl and high(ish) ldl. Apob was of course never checked until recently at my request and it came back 85. Despite my doctor saying I had no need for more cardio workups I requested a cac score anyways. It came back at 138. All but five of that in the LAD. A huge surprise to say the least. I was told to keep doing what I am doing regarding diet and exercise and prescribed a statin which I am hesitant to take. I have a second opinion appointment coming up soon. I am a 46 year old male, non-diabetic and my last lipids were hdl 56 (a year ago was 20), ldl 126, apob 85, and Lp(a) 15, triglycerides 50. Scary and frustrating to say the least.
take the damn statin lol
Jan I had a CAC of 0% in September I had a heart attack from a 60% narrowing. Cant believe it!
That's because soft plaque, which is not identified by a regular heart CT scan so does not show up in a CAC score, is the problem, not calcified hard plaque.
2:28 "It's only going to go up." Boo. I hope not. Like others posting below, the hope is to reverse the damage.
Had a cac 2 yrs ago at 67. To my horror it was 1240.. the radiologist stopped further testing and advised a cardiologist appointment immediately. After extensive testing sonagram/stress etc. The cardiologist called me and said the tests showed my arteries were clear and calcium manifested either on the outside or maybe within the artery walls..I work out intensely with weights and some cardio and the tests showed I'm in exceptional condition.i am confused.. Did I damage my coronary arteries with too intense exercise?
It's all confusing. Did you ever get to the bottom of it?
Initially when inquiring about my tests the cardiologist repeatedly asked about chest pain cramps breathlessness when exercising? I told him never..after extensive stress tests with injected dye, a sonagram,, he found there was either calcium manifested on the outside of my arteries or in the epithelial cells..but no build up or blockage and he cleared me to exercise.. I asked him what the hell caused it and he frankly couldn't say.. maybe some type of inflammation as the technician performing sonogram asked if i ever contracted a weird virus..there is some data suggesting very intense exertion has caused this kind of issue on some athletes.
Btw looking at the cat scan of my chest my arteries lit up like I was radio active.. lol. no wonder they thought I was ready to drop..
You can reverse it
I had a CAC score of 70 at 35 in my LAD. Found out after I broke my rib doing Jiu Jitsu. ApoB is 57, LPa is 17.
You can reverse it
How do they compare to a ink type CT aniogram?
Im 46 and my calcium score is 9 and “mild atherosclerosis” was found.
My calcium score is 10. I am 53. What should I do?
If Peter acknowledges that there are people of old age with high apo b and zero calcium score, that means either that they had low apo b all their life, or that apo b by itself doesn't cause atherosclerosis. If the latter is the case, then there's no reason to try to lower young people's apo b - which even if helped, isn't without cost.
I am completely uneducated in biochemistry but how in the fuck can apoB be causal if there are so many people with astoundingly high ldl/apob that do not have any significant plaque it just doesnt make any sense. i think they clearly do not understand this
"If Peter acknowledges that there are people of old age who smoke and with no lung cancer, that means either that they never smoked, or that smoking doesn't cause lung cancer. If the latter is the case, then there's no reason to try to not smoke - which even if helped, isn't without cost of enjoyment."
A causal relationship does not guarantee the outcome. Not all smokers get lung cancer.
@@ladagspa2008 Cancer and atherosclerosis aren't comparable, you can compare cancer with heart attacks though. You either have cancer or heart attack, or you don't. Atherosclerosis is gradual, if Apo B causes it, you can't possibly have zero calcium score and high Apo B.
You have an abysmal understanding of causality. Presence of the causal factor doesn't guarantee the effect. It only increases the probability of effect occurring, doesn't make the probability 100%.
People who have genes protective against plaques will not get plaques in spite of high ApoB. But we know that its ApoB/LDLc which is literally found in the plaques upon biopsy.
@@ladagspa2008 You're contradicting yourself - in your own hypothesis that some genes might be protective from atherosclerosis, for the person who has these genes Apo B doesn't cause atherosclerosis.
If you find wood in the fire, it doesn't follow that wood causes fire. It might be necessary, but not a sufficient factor.
Ok you CAC isn’t zero, what is the treatment?