Gastrulation - Human Embryology - 3rd Week [Animated] - MedicoVisual

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  • เผยแพร่เมื่อ 9 พ.ค. 2024
  • In this video, Dr. Aizaz from MedicoVisual explains the process of Gastrulation [Third week of Human Embryology] using 3D and 2D animations and memes.
    00:00 Intro
    01:40 Bilaminar germ disc
    02:23 Epiblasts release Hyaluronic acid
    03:12 Formation of Primitive streak and Primitive/Hensen's node
    04:44 Role of Primitive streak in Axis determination
    05:26 Role of Anterior Visceral Endoderm in inhibition of Primitive streak at cranial end
    06:20 Why is Anterior Visceral Endoderm called "Anterior"
    08:19 E-cadherin downregulation and epithelium to mesenchymal transition
    09:17 What are Bottle cells or Flask cells and Mesenchymal cells
    10:24 Formation Primitive Groove and Primitive Pit
    12:54 Hypobasts are displaced to Yolk sac endoderm that induces formation of Blood islands
    16:20 Sacrococcygeal Teratoma
    18:02 Why Gastrulation is named so when there is no formation of GIT during this process
    20:37 Review
    Website: www.medicovisual.com
    Email: draizaz@medicovisual.com

ความคิดเห็น • 133

  • @MedicoVisual
    @MedicoVisual  3 ปีที่แล้ว +15

    At 05:52, there is a mistake. Hypoblast cells give important instructions to overlying *"Epiblast cells"* [Not Hypoblasts]

    • @anwarulhaq535
      @anwarulhaq535 3 ปีที่แล้ว +1

      Good easily understandable presentation.it is very helpfull for first professional students

    • @MedicoVisual
      @MedicoVisual  3 ปีที่แล้ว

      @@anwarulhaq535 Thank you

    • @ubairaaltaf1324
      @ubairaaltaf1324 ปีที่แล้ว +2

      How is left and right determined?

    • @MedicoVisual
      @MedicoVisual  ปีที่แล้ว +3

      @@ubairaaltaf1324 primitive strak is at the caudal side. Anything to the right of primitive streak is right sided and anything to its left is left sided. Simple as that.

    • @ubairaaltaf1324
      @ubairaaltaf1324 ปีที่แล้ว +2

      @@MedicoVisual Dont we need to know where the face of embryo is pointing for determination of rt and left?

  • @mmott3432
    @mmott3432 6 หลายเดือนก่อน +3

    6:22 😂 That was unexpected and added to an already great show

  • @ashiqhussain8919
    @ashiqhussain8919 2 ปีที่แล้ว +52

    I am an associate professor of Anatomy and teach at medical school but on this channel I am a student, nothing more to say.

    • @MedicoVisual
      @MedicoVisual  2 ปีที่แล้ว +9

      I am honoured, professor. 🤗

  • @farazsaleem3417
    @farazsaleem3417 3 ปีที่แล้ว +9

    This is premium stuff !
    Idk how content of this Quality is still free !

    • @MedicoVisual
      @MedicoVisual  3 ปีที่แล้ว +3

      Thanks a lot for such words of appreciation

  • @firdusarayasmin3245
    @firdusarayasmin3245 2 ปีที่แล้ว +12

    Never seen such amazing lectures on you tube. Don't know how to thank you. Skipped embryology in my first year but now watching you videos have made embryology easy for me.

    • @MedicoVisual
      @MedicoVisual  2 ปีที่แล้ว +1

      Wonderful! Thank you so much for appreciation.

    • @waqasman3067
      @waqasman3067 2 ปีที่แล้ว

      Sir please tell me about area pellucida

  • @kesavnag9962
    @kesavnag9962 2 ปีที่แล้ว +14

    We should thank you. U shouldn't thank us because u made it easy to understand and explained each and every question that I have..! Once again thank you🙏🙏🙏 bro 😘😘

    • @MedicoVisual
      @MedicoVisual  2 ปีที่แล้ว

      So nice of you. I am blessed to have such audience 😊

  • @pratikshyarijal1913
    @pratikshyarijal1913 ปีที่แล้ว +13

    I am a second year medical student. Embryology has always been tough for me because I couldn't imagine. We had studied about gastrulation in first year but my orientation was lacking. I came to this video after watching 3D tour of second week of development. I can't thank you enough. Now my orientation is clear. I could finally understand every bits and pieces. Thank you for this animation sir.
    Love from Nepal 🇳🇵

    • @MedicoVisual
      @MedicoVisual  ปีที่แล้ว

      Thank you so much for your appreciation

  • @dyjfrtujfdw
    @dyjfrtujfdw หลายเดือนก่อน +2

    that was the most sensed and perfect lecture of emberyology i ever had🤩🤩😍😍😍😍😍😍😍😍thanks a loooot

  • @elahanoor7048
    @elahanoor7048 2 ปีที่แล้ว +4

    The fact that you put blood island in actual form of island xD
    Thank you so so much for thesw amazing animations ! They are brain cell savers

  • @shefanjahan3306
    @shefanjahan3306 2 ปีที่แล้ว +5

    Excellent content!
    Please don’t stop ever.

  • @missionncert85
    @missionncert85 2 หลายเดือนก่อน +1

    Sir ur a life saver in mbbs first year ,i try to many platform like Marrow,prepladder but can't understand the concept, Thank u so much ,God bless u ,stay always happy ❤

  • @kamranwani396
    @kamranwani396 3 หลายเดือนก่อน +1

    Sir I was facing alot of difficulties in this topic but after watching your video I understand everything and also all my doubts are clear now ,plzzz sir. Make videos of more chapters sir ,❤❤❤❤

  • @harmanpreetkaur4608
    @harmanpreetkaur4608 5 หลายเดือนก่อน +1

    I am first year med student and your lectures are really helping me a lot to understand the concepts.Thanku soo much!

  • @user-bo9bp9fk5t
    @user-bo9bp9fk5t 6 หลายเดือนก่อน +2

    I like when he get angry about the names😂

  • @misBugzHere
    @misBugzHere ปีที่แล้ว +5

    Sir,this sequence of lectures,your way of explaining each nd every step is beyond the words "Thank You"...May Allah Almighty bless u with whatever you want(Amen).🤲🏼♥️

    • @MedicoVisual
      @MedicoVisual  ปีที่แล้ว +1

      So nice of you. Thank you so much for your appreciation.

  • @manyaagrawal9964
    @manyaagrawal9964 ปีที่แล้ว

    Great job of making a difficult thing to be explained in detail with so much ease.....

  • @kaavyadharsini7422
    @kaavyadharsini7422 4 หลายเดือนก่อน +1

    Thankyou very much sir for making me visualize the concept.I will never forget it.

  • @sauravsinha1151
    @sauravsinha1151 11 หลายเดือนก่อน +1

    I am a first year mbbs student
    Very much worried about how to approach Embryology but now you made it easy for me
    Thanks a lot sir
    ❤️❤️

  • @ahyaanmasrat1458
    @ahyaanmasrat1458 5 หลายเดือนก่อน +1

    Ur lecture r the best ones...thanku so much..

  • @KailashSharma-sz9mh
    @KailashSharma-sz9mh 4 หลายเดือนก่อน +1

    Sir I am amazed with deepens of the knowledge and animation

  • @hamzaanees2811
    @hamzaanees2811 หลายเดือนก่อน +1

    Jazakallah khair sir.! Thank you so so so much.

  • @vasanthipillay9812
    @vasanthipillay9812 2 ปีที่แล้ว +7

    I love the way you teach. You have a good sense of humour. As well you can make a complex topic very simple and easy to understand. Only good teachers can do this. Thank you for this class :-)

  • @ellios5734
    @ellios5734 ปีที่แล้ว +3

    I feel so lucky that I found such good video, very well explained thank you very much please keep making videos like this.

    • @MedicoVisual
      @MedicoVisual  ปีที่แล้ว

      I too am so lucky to have such nice audience who regularly motivate me to work harder on this project. Thank you so very much for this uplifting comment. You are most welcome.

    • @sharika5019
      @sharika5019 หลายเดือนก่อน +1

      ​​@@MedicoVisualyour lectures are awesome n a visual treat n understandably illustrated. Thank u!😊.keep making more medical lectures please

  • @welcome_medico
    @welcome_medico 3 หลายเดือนก่อน +1

    Thanks sir you aree doing great job.... thanks for explaining things so nicely.. earlier i was finding difficulty in understanding the embryology....in textbooks it is written in very confusing way... thankyou sir

  • @pseudodoctor2797
    @pseudodoctor2797 ปีที่แล้ว +2

    Simply briliant. Keep growing bro. You are great.

  • @anwarsultana1776
    @anwarsultana1776 3 ปีที่แล้ว +3

    Very retainable and easily understandable lecturr

  • @vishweshpatel1997
    @vishweshpatel1997 2 ปีที่แล้ว +4

    another best video on the topic !!!

  • @muthuraj8901
    @muthuraj8901 ปีที่แล้ว

    Good work buddy thank you 😊 🙏

  • @nithyasreeoruganty
    @nithyasreeoruganty 8 หลายเดือนก่อน +1

    This 3D visualization and your explanation helps us a lot to understand embryology in a simple and easy way..Thankyou so much sir..

  • @mamunasharif3067
    @mamunasharif3067 2 ปีที่แล้ว +2

    Please sir continue your lectures...they are so helpful for university students

  • @lavanyagoyal1525
    @lavanyagoyal1525 3 ปีที่แล้ว +4

    this is the best !! GREAT JOB!! pls make more videos of more and more topics.U will make mbbs so much easier!!

  • @anchalkharyal4158
    @anchalkharyal4158 2 ปีที่แล้ว +2

    Thanks no words to explain your work 🙏

  • @BilalAli-se5uw
    @BilalAli-se5uw 2 ปีที่แล้ว +4

    Visual conceptualisation
    Logical Reasoning
    Rare Very Rare in embryology

    • @MedicoVisual
      @MedicoVisual  2 ปีที่แล้ว

      Such a beautiful comment. Thanks

  • @RoquiaNaveed-uz4fd
    @RoquiaNaveed-uz4fd ปีที่แล้ว +1

    Amazing sir it's really very helpful for any student 👍

  • @haziqfarooq2942
    @haziqfarooq2942 5 หลายเดือนก่อน +1

    You are amazing yaar❤

  • @bublisoniyak6227
    @bublisoniyak6227 2 ปีที่แล้ว +1

    Thank you so so much 😭❤️🙌

  • @deepgaming1360
    @deepgaming1360 2 ปีที่แล้ว +2

    Sir I can't thank you enough! , you are just amazing!!!...

  • @medstudent7583
    @medstudent7583 3 ปีที่แล้ว +3

    Thank u so much , your videos are so helpful

    • @MedicoVisual
      @MedicoVisual  3 ปีที่แล้ว

      Most welcome! I am so glad that you like them.

  • @elaishine395
    @elaishine395 ปีที่แล้ว +1

    Super sir thaks very mach i have got a big help from the diagram

  • @disconnectedaccount422
    @disconnectedaccount422 10 หลายเดือนก่อน +1

    i love youuuuuu sir thank you very much

  • @maiklrock324
    @maiklrock324 ปีที่แล้ว +2

    Is the primitive streak give information to create human body ????

  • @DrMSSR_tips_tricks
    @DrMSSR_tips_tricks 2 ปีที่แล้ว +1

    Op explaination ...need more

  • @yusufkurdi3582
    @yusufkurdi3582 ปีที่แล้ว +2

    I have questions is the primitive streak give information to create human body ?? Some people say primitive streak is responsible for creating human body (embryo) is that true ??

    • @MedicoVisual
      @MedicoVisual  ปีที่แล้ว +1

      Yes that's true

    • @yusufkurdi3582
      @yusufkurdi3582 ปีที่แล้ว

      @@MedicoVisual so the primitive streak is giving the full information for creating our eyes ears heart and everything else in our body ??

  • @areebanadeem4988
    @areebanadeem4988 ปีที่แล้ว +1

    Best...best.....best.....best........you're BEST❤

  • @futurezoologist9177
    @futurezoologist9177 ปีที่แล้ว +1

    It's amazing

  • @razerblue6677
    @razerblue6677 2 ปีที่แล้ว +2

    You presented and answered questions i didn't even think of! Amazing work! You earned a sub from me😄. Please keep up the AMAZING work!
    Love from Sri lanka 🇱🇰❤

  • @maiklrock324
    @maiklrock324 ปีที่แล้ว +4

    where the *** is anterior here?😂😂😂🤣🤣

  • @fatimahkadiku7368
    @fatimahkadiku7368 8 หลายเดือนก่อน +1

    Thank u so much for this explanation. I'm literally watching and clapping. However, I would like to know where the splanchnic mesoderm came from because I used to think it was so e of the cells from the ectoderm layer that formed it.

    • @MedicoVisual
      @MedicoVisual  7 หลายเดือนก่อน

      I sincerely apologize for the late reply. And thank you so much for your appreciation.
      The origin of extra-embryonic mesoderm (both splanchnopleuric and somatopleuric) is controversial. Most people believe that it arise from hypoblast cells. (specifically, yolk sac endoderm). While some say they arise from cytotrophoblast or from epiblast. There is some contribution from the epiblast as well. During gastrulation, some of the epiblast cells migrate laterally to contribute towards the extra-emrbyonic mesoderm.
      In summary, there is no definite answer to this question. But most common view is that they originate from "Yolk Sac Endoderm".
      Watch the video on Second Week part 2 to learn more: th-cam.com/video/8Okp0FzWjXA/w-d-xo.html

  • @yusufkurdi3582
    @yusufkurdi3582 ปีที่แล้ว +3

    Please brother its really important 🧠 is the primitive streak give information to create human body (embryo) ??

    • @MedicoVisual
      @MedicoVisual  ปีที่แล้ว +2

      Information for whole of the human being is in every cell starting from zygote (in the form of DNA). Epiblast forms the complete human. The primitive streak "guides" the epiblast in forming the three germ layers. So in a sense we can say that primitive streak contains the info to create human being.

    • @yusufkurdi3582
      @yusufkurdi3582 ปีที่แล้ว

      @@MedicoVisual thank you so much ❤ so the primitive streak has information to create human embryo rights ??

    • @MedicoVisual
      @MedicoVisual  ปีที่แล้ว

      @@yusufkurdi3582 yes

    • @yusufkurdi3582
      @yusufkurdi3582 ปีที่แล้ว +2

      @@MedicoVisual this question was so important to me thank you and I love the video by the way 💙👍great explanation

    • @MedicoVisual
      @MedicoVisual  ปีที่แล้ว +1

      @@yusufkurdi3582 always welcome. By the way, I am curious why is this question so important for you?

  • @yusufkurdi3582
    @yusufkurdi3582 ปีที่แล้ว +1

    Sorry for asking again but is the primitive streak give information to create our body or it just help ????? please I need the answer 💚

  • @treverzuze6723
    @treverzuze6723 6 หลายเดือนก่อน +1

    Thank you medicoVisual , and I kindly have some questions Doctor, that I would like to ask.

    • @MedicoVisual
      @MedicoVisual  6 หลายเดือนก่อน

      Sure. Please ask

  • @yousrabk1111
    @yousrabk1111 ปีที่แล้ว +2

    hello can i ask a question please? what is the name of the app or site that you use for these presentations

    • @MedicoVisual
      @MedicoVisual  ปีที่แล้ว

      For 3D modeling and Animation; I use Blender. For 2D graphics and presentation; I use PowerPoint.

  • @houriak848
    @houriak848 หลายเดือนก่อน +1

    Sir i have a question when the epiblast in periphery migrate goward the center ofc the adhesive junction gonna be broken so the cell can migrate when they reach primitive streak thy gonna establish another junctions so we need we break it down so they can migration down through the groove ?

    • @MedicoVisual
      @MedicoVisual  หลายเดือนก่อน

      Yes, that's correct. Intercellular junctions are broken and the epithelial cells are converted to mesenchymal cells.

  • @yusufkurdi3582
    @yusufkurdi3582 ปีที่แล้ว

    so primitive streak give informations to create human body (embryo) ????? I need the answer and I love the video ❤👍

  • @aakashsahupoetry7373
    @aakashsahupoetry7373 ปีที่แล้ว

    Thank you 😊 Sir can you suggest me best book for embryology mbbs. 1st proff

  • @taashin2863
    @taashin2863 7 หลายเดือนก่อน +1

    Are the first blood cells that form in the yolk sack coming from epiblast or hypoblast origin? As I understand it’s coming from hypoblast so it’s not completely true that the epiblast gives rise to all types of cells in the embryo because some blood cells formed by hypoblast right ? Or am I wrong ?

    • @MedicoVisual
      @MedicoVisual  7 หลายเดือนก่อน

      Blood cells develop neither from epiblast nor from hypoblast. They develop from the mesoderm.

    • @taashin2863
      @taashin2863 7 หลายเดือนก่อน

      @@MedicoVisual
      Thank you very much for your answer doctor
      Do you mean the extra or the intra embryonic mesoderm ? And doesn’t that mean there are embryonic cells that doesn’t form by the epiblast ?

    • @MedicoVisual
      @MedicoVisual  7 หลายเดือนก่อน

      @@taashin2863 you are always welcome :-)
      Most of the blood cells are derived from the IntraEmbryonic mesoderm.. However some early blood cells are derived from the blood islands that form within the extraembryonic mesoderm. The origin of extraembryonic mesoderm is controversial. Most people believe that it arise from hypoblast cells. (specifically, yolk sac endoderm). While some say they arise from cytotrophoblast or from epiblast.
      So if the hypoblast origin of extraembryonic mesoderm is true, then yes, early blood cells are NOT epiblastic in origin.
      Great question though

    • @taashin2863
      @taashin2863 7 หลายเดือนก่อน +1

      Thank you very much Doctor
      I appreciate your help

    • @MedicoVisual
      @MedicoVisual  7 หลายเดือนก่อน

      @@taashin2863 Always welcome 🙂

  • @goodbook6000
    @goodbook6000 ปีที่แล้ว +1

    Your videos are just amazing .......
    I have.paused the video to do the comment ..
    How can i talk to you personally??

    • @MedicoVisual
      @MedicoVisual  ปีที่แล้ว

      Email: draizaz@medicovisual.com
      WhatsApp: +923037241030

  • @maiklrock324
    @maiklrock324 ปีที่แล้ว

    to be sure that the caudal eminence was the primitive streak / in goggle just write 👉 (the caudal eminence derived from the primitive streak)

  • @fimanekamatthias175
    @fimanekamatthias175 11 หลายเดือนก่อน +1

    "because it looks like a monster "😭

    • @MedicoVisual
      @MedicoVisual  11 หลายเดือนก่อน

      What looks like a monster?

  • @nainaalam9482
    @nainaalam9482 5 หลายเดือนก่อน

    please upload videos on cell biology topics ...

    • @MedicoVisual
      @MedicoVisual  5 หลายเดือนก่อน

      Thanks for the feedback. I will work on it.

  • @alisha7739
    @alisha7739 2 ปีที่แล้ว +2

    Sir please make video on cvs embryology

    • @MedicoVisual
      @MedicoVisual  2 ปีที่แล้ว

      Thank you for the comment. CVS Embryology will be provided as a part of paid course. Details will be announced soon

  • @zalanibrahim5611
    @zalanibrahim5611 9 หลายเดือนก่อน +1

    is mesoderm and mesenchyme same ?

    • @MedicoVisual
      @MedicoVisual  9 หลายเดือนก่อน +1

      There are two main type of embryonic cells:
      1. Epithelial cells: that are structurally defined properly i.e. They have specific shape like Cuboidal, Columnar, Squamous etc. Furthermore, the epithelial cells are inter-connected with each other through cell-to-cell interactions.
      2. Mesenchymal cells: On the other hand, are irregularly shaped and are not connected with each other. They are interspersed in a ground substance.
      The mesoderm is the major source of mesenchyme. That is why often in literature specially during teaching 3rd week, these terms are interchangeably used. But please note that mesenchyme can also arise from Neural Crest Cells. And sometimes by other layers.

    • @zalanibrahim5611
      @zalanibrahim5611 9 หลายเดือนก่อน +1

      @@MedicoVisual Thank You for detailed answer ❤

    • @MedicoVisual
      @MedicoVisual  9 หลายเดือนก่อน

      Always welcome

  • @annettaannasheby5604
    @annettaannasheby5604 ปีที่แล้ว +1

    Please teach development of head and neck

    • @MedicoVisual
      @MedicoVisual  ปีที่แล้ว

      A complete 3D course on Head and Neck Embryology is already available at MedicoVisual (www.medicovisual.com/courses/premium-head-and-neck-embryology-masterclass-excluding-development-of-teeth). Also check the free video from that course: th-cam.com/video/zgvR6VuMLkw/w-d-xo.html
      Feel free to contact if you need any help in enrolling. Email: draizaz@medicovisual.com.
      WhatsApp +923037241030

  • @maiklrock324
    @maiklrock324 ปีที่แล้ว

    and to be sure that coccyx (tailbone) was the caudal eminence / in goggle just write 👉 (the coccyx arises from the caudal eminence)

  • @maiklrock324
    @maiklrock324 ปีที่แล้ว

    Somany Muslims talked about this Islam miracle the primitive streak / but I just wanted to be sure that the primitive streak is involved of creating the human embryo 💙

  • @KRVERMA-pt7jt
    @KRVERMA-pt7jt 2 ปีที่แล้ว +3

    It feels illegal to watch it for free!!

    • @MedicoVisual
      @MedicoVisual  2 ปีที่แล้ว +1

      Thanks a lot for your kind appreciation. Feeling so grateful

    • @shefanjahan3306
      @shefanjahan3306 2 ปีที่แล้ว +1

      So true!

  • @elwasad5710
    @elwasad5710 2 ปีที่แล้ว +1

    Conventions my friends conventions 😅

  • @maiklrock324
    @maiklrock324 ปีที่แล้ว

    In goggle just write 👉 (the coccyx is the remnant of caudal eminence) 🙂💚

  • @user-lu1cj3pv5t
    @user-lu1cj3pv5t 2 ปีที่แล้ว

    🇮🇶 ❤️

  • @vishalmaharajan6712
    @vishalmaharajan6712 ปีที่แล้ว +1

    man i love you😘😘 am not gay though😂😂😂

  • @maiklrock324
    @maiklrock324 ปีที่แล้ว

    prophet Muhammad he said: god created humans from (coccyx) tail bone / and science says this coccyx before it was (the caudal eminence) and this (caudal eminence) before it was (the primitive streak) 🧠🧠🧠

  • @yusufkurdi3582
    @yusufkurdi3582 ปีที่แล้ว +1

    I was gonna tell you why this question so important to me but you asked anyway / I can prove my claim on Google if you want just ask me anytime / thank you again you really helped me ❤💚

  • @maiklrock324
    @maiklrock324 ปีที่แล้ว

    now I shared the reference of this hadith with you with proof on Google / good bye and good luck ❤👋