Introduction to Buffer System || Regulation of pH || Acid Base Balance || Buffers in Biochemistry

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  • เผยแพร่เมื่อ 1 ต.ค. 2024
  • Buffer system for the acid base balance and regulation of pH - This video is on the introduction to Acids, Bases, Buffers, physiological pH of blood and different types of extracellular buffer and intra cellular buffer which are first line of defense for the regulation of pH.
    Acids, Bases and buffers - 00:24 minutes
    Normal pH of the body fluids - 01:45 minutes
    Why maintenance of a pH is important - 02:28 minutes
    Fixed acids or Non volatile acids - 03:25 minutes
    Volatile acids - 03:50 minutes
    Metabolic Sources Of Bases - 04:05 minutes
    Mechanism for the regulation of pH - 04:40 minutes
    Buffering Capacity - 06:40 minutes
    pKa - 06:48 minutes
    Intracellular and Extracellular buffer - 07:42 minutes
    Bicarbonate Buffer system - 08:56 minutes
    Mechanism of Bicarbonate buffer - 09:43 minutes
    Phosphate buffer system - 12:47 minutes
    Mechanism of phosphate buffer - 13:08 minutes
    Protein buffer - 15:03 minutes
    Hemoglobin buffer - 16:12 minutes
    Mechanism of hemoglobin buffer - 17:14 minutes
    Chloride Shift - 18:28 minutes
    NEET PG Biochemistry MCQs - 21:03 minutes
    ACIDS, BASES AND BUFFERS
    An acid is defined as a substance that releases protons or hydrogen ions (H+), e.g. hydrochloric acid (HCI), carbonic acid (H2CO3).
    base is a substance that accepts protons or hydrogen ions, e.g. bicarbonate ion (HCO3-), and HPO4- -
    Buffer is a solution of weak acid and its corresponding salt which resists a change in pH when a small amount of acid or base is added to it.
    By buffering mechanism a strong acid (or base) is replaced by a weaker one.
    Normal pH Of The Body Fluids
    The normal pH of arterial blood is 7.4
    pH of venous blood and interstitial fluids is about 7.35
    The pH of blood is maintained within a remarkable constant level of 7.35 to 7.45.
    Regulatory Mechanisms to maintain normal Blood pH
    Buffer mechanism: First line of defense
    The respiratory mechanism: Second line of defense
    Renal mechanism: Third line of defense.
    Blood Buffer
    Buffer System Extracellular buffer Intracellularbuffer
    Bicarbonate NaHCO3/ H2CO3 KHCO3/H2CO3
    Phosphate Na2HPO4/NaH2PO4 K2HPO4/KH2PO4
    Protein Na Protein/H. Protein KHb/H.Hb
    KHbO2/H.HbO2
    #biochemistrybasicsbydramit #pHregulation #buffersystem #acidbasebalance #NEETPG #NEETPGbiochemistry #USMLE

ความคิดเห็น • 66

  • @tagedumi8063
    @tagedumi8063 3 ปีที่แล้ว +13

    Short, crisp and on to the point. Just what I was looking for.
    Thank you for simplifying the topic sir.

  • @raghadbarjas7257
    @raghadbarjas7257 2 ปีที่แล้ว +5

    This was so helpful for me!!!!!!! Thank you so much may allah bless you ❤️💕💕💕💕💕💕💕💕💕💕💘💘💘💘💘💕💕💕💕💕💘💘💕💘💕💘💕💘💕💕💕💕💘❤️❤️❤️❤️💕❤️💕❤️💕❤️💕❤️💕❤️💕❤️

  • @arungaliyt9186
    @arungaliyt9186 3 ปีที่แล้ว +3

    **02.26 wrong explanation**
    Increasing Of PH is “Acidosis” Decreasing of PH is “Alkalosis”

    • @Biochemistrybasics
      @Biochemistrybasics  3 ปีที่แล้ว +1

      No, increase in pH is alkalosis and decrease in pH is acidosis

    • @arungaliyt9186
      @arungaliyt9186 3 ปีที่แล้ว

      I’m so confused! I thought 💭 Acidosis is a condition in which there is too much acid in the body fluids. It is the opposite of alkalosis (a condition in which there is too much base in the body fluids). Am i right? Or wrong ? Let me know about this?

    • @Biochemistrybasics
      @Biochemistrybasics  3 ปีที่แล้ว +1

      @@arungaliyt9186 You are absolutely correct. Normal physiological pH of blood is 7.35-7.45. If pH is less than 7.35 dn it's acidosis and if it is greater than 7.45 dn it is Alkalosis

    • @arungaliyt9186
      @arungaliyt9186 3 ปีที่แล้ว +2

      Oh sry! I’m about to tell that increasing on H+ ions in blood plasma is Acidosis and it indicates decreased PH and decreasing of H+ ions is Alkalosis and it indicates increased PH. (Thanks for your response 🙏👍🏻👍🏻🤝🤝)

    • @Biochemistrybasics
      @Biochemistrybasics  3 ปีที่แล้ว +1

      @@arungaliyt9186 Yes dear. My pleasure

  • @rajeevreddy3315
    @rajeevreddy3315 3 ปีที่แล้ว +2

    Buffer is a solution..... Not a substance
    NYC presentation and clearly explained

  • @aseelmaher6611
    @aseelmaher6611 4 ปีที่แล้ว +5

    Thank you ...
    I have a question
    Does phosporic acid act as a buffer ?

    • @Biochemistrybasics
      @Biochemistrybasics  4 ปีที่แล้ว +2

      Inorganic Phosphates act as a buffers

    • @aseelmaher6611
      @aseelmaher6611 4 ปีที่แล้ว +2

      Ok thanks

    • @rajeevreddy3315
      @rajeevreddy3315 3 ปีที่แล้ว +1

      Phosphate is the major Intracellular buffer and Bicarbonate is the major extracellular buffer

  • @crazysiva7378
    @crazysiva7378 ปีที่แล้ว +2

    Sir pdf format ah send panringala please🙏🏻

  • @Fajilath-kz3jk
    @Fajilath-kz3jk 11 หลายเดือนก่อน +2

    07:29 blood buffers starts

  • @carafadaleeli272
    @carafadaleeli272 3 ปีที่แล้ว +2

    please what is relationship between HP and potassium K ??

  • @shivashankar5039
    @shivashankar5039 3 ปีที่แล้ว +2

    Sir can you please share the ppt?

  • @_unknowngirl_9101
    @_unknowngirl_9101 3 ปีที่แล้ว +2

    Thank you sir ❤️😌

  • @prashantgupta9777
    @prashantgupta9777 3 ปีที่แล้ว +2

    Sir, please provide notes of all lecture video on the website 🙏🙏🙏🙏🙏🙏🙏 please sir

    • @Biochemistrybasics
      @Biochemistrybasics  3 ปีที่แล้ว

      Yes half of them are already uploaded. Remaining one I will update in the few days.

    • @prashantgupta9777
      @prashantgupta9777 3 ปีที่แล้ว +1

      @@Biochemistrybasics THANK YOU so much sir🙏🙏, i request to you provide notes as soon as possible, because my 1st year exam hold on January

    • @Biochemistrybasics
      @Biochemistrybasics  3 ปีที่แล้ว

      @@prashantgupta9777 no issues

  • @anshudeo9224
    @anshudeo9224 2 ปีที่แล้ว +2

    So so much thank you sir.
    Was looking for this since the begining and finally understood the concept. ☺

  • @mirriamnankamba2621
    @mirriamnankamba2621 ปีที่แล้ว +1

    So helpful thank you sir .

  • @rubeenagurung1517
    @rubeenagurung1517 4 ปีที่แล้ว +1

    In bicarbonate buffer system can we use weak acid as carbonic acid and strong base salt as sodium bicarbonate??

  • @SultanaNazmun_Naim_
    @SultanaNazmun_Naim_ 4 ปีที่แล้ว +3

    Thank you sir... it's really helpful 👍

    • @Biochemistrybasics
      @Biochemistrybasics  4 ปีที่แล้ว +1

      You are welcome 😊. Keep loving biochemistry and do spread the word about the channel 😊

  • @evelynminz3881
    @evelynminz3881 3 ปีที่แล้ว +2

    So easily explained .Must watch

  • @mahida9838
    @mahida9838 4 ปีที่แล้ว +3

    Thank you sir

    • @Biochemistrybasics
      @Biochemistrybasics  4 ปีที่แล้ว

      You are welcome tushar. Please spread the word. Tk cr 😇

  • @vevyovi1715
    @vevyovi1715 2 ปีที่แล้ว +1

    thank you very much it is the most detailed video which I encountred

  • @adsrrdtz4597
    @adsrrdtz4597 3 ปีที่แล้ว +1

    Thank 🙏 u soo much sir
    Sir is there notes for ur lectures

  • @subhashreemahalik1665
    @subhashreemahalik1665 2 ปีที่แล้ว +1

    thank you so much for making the things very easy.

  • @aashishahuja5792
    @aashishahuja5792 4 ปีที่แล้ว +2

    Thank u sir

  • @Maru-hr2dg
    @Maru-hr2dg 3 ปีที่แล้ว +1

    👍🏻 Great sir
    Short and easy

  • @derrickzulu2907
    @derrickzulu2907 3 ปีที่แล้ว +1

    thanks

  • @gamearena4259
    @gamearena4259 3 ปีที่แล้ว +1

    Thanks

  • @rohiniwaghmare8765
    @rohiniwaghmare8765 2 ปีที่แล้ว

    Sir ppt bhetel k

  • @SurajYadav-up4bn
    @SurajYadav-up4bn ปีที่แล้ว

    🙏🙏🙏🙏🙏👏👏👏👏👏😍😍

  • @sarahgamaleldean3775
    @sarahgamaleldean3775 2 ปีที่แล้ว +1

    Thanks sir...l will follow the other videos for you to get more and more informations...thank you again

    • @Biochemistrybasics
      @Biochemistrybasics  2 ปีที่แล้ว

      You are most welcome dear. Keep loving biochemistry

  • @gulfwarveteran8528
    @gulfwarveteran8528 4 ปีที่แล้ว +5

    Thanks sir i understood the topic thoroughly

    • @Biochemistrybasics
      @Biochemistrybasics  4 ปีที่แล้ว +2

      🙏😇

    • @hayesjamie4073
      @hayesjamie4073 3 ปีที่แล้ว +1

      i guess it is quite off topic but do anyone know a good site to stream newly released movies online?

    • @landonjay4143
      @landonjay4143 3 ปีที่แล้ว +1

      @Hayes Jamie try Flixzone. Just search on google for it =)

    • @deaconlondon6170
      @deaconlondon6170 3 ปีที่แล้ว +1

      @Landon Jay definitely, I've been watching on FlixZone for years myself =)

    • @hayesjamie4073
      @hayesjamie4073 3 ปีที่แล้ว +1

      @Landon Jay Thanks, I went there and it seems to work :D I really appreciate it!!

  • @muhammadshamsuddin795
    @muhammadshamsuddin795 3 ปีที่แล้ว

    Sir could you please share this lecture note? Please sir 😇 It was awesome lecture