Thank you. I don’t remember much of my chemistry and only rudimentary biology from high school. I was recently diagnosed with CML and am now taking a TKI. This helps explain TK better and has helped with my understanding. I thank you for that!
I just want to say thank you 😊 I have been struggling to understand this and you just made it with four and a half minutes you should be my professor you would make a better job than he did
Hi, thank you for this video. It was short, simple, and very clear. I had one question that I'm confused about. Do both binding sites need to be filled for RTK's to become dimerized? What would happen if only one binding site is filled and the other one isn't? Would that ligand detach or would it stay there until the other site is filled?
Does every tyrosine kinase take phosphate from ATP present in cytoplasm or does only one of them when phosphorylation transfer phosphorous to a relative of tyrosine kinase colloquially, meaning that each one when phosphorylation transmits phosphorous to her sister and I think the first is correct, answer me please
Very good job i will Ask you for a minute when th groupe of six tyrosine phosporated so that give us Always a six cell respense if i am false please show me the correct answer thx again
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I was struggling with understanding this. And 4,38 minutes here. I understand. You saved a lot of time for me. I'm very grateful.
currently in my first year of neuroscience and this helped me a lot!!! you explained it so well!!!
Please explain Protein kinase R
Hey , im in med school in French, and I didn't find any french video about this idea, but you're video was very easy to understand, thank you !
you did a nice job explaining it, thank you! I wish you had a continuation explaining about Ras and its cascade.
great idea have you found any videos about that RAS proteins?
Thank you. I don’t remember much of my chemistry and only rudimentary biology from high school. I was recently diagnosed with CML and am now taking a TKI. This helps explain TK better and has helped with my understanding. I thank you for that!
Great video. Concise, detailed, and informative. Much appreciated.
omg thank you so much you explained it sooo much better than my college professor!!!!
Wow this saved me, I have watched so many videos and this is the only one that made sense, thank you
Thank you so much for this! really helped clear up this process
00:11 tyrosine(아미노산)이 여러 개 결합한 화합물-> polypeptide, protein
00:28 tyrosine 위치
Thank you!!
Même en ne parlant qu'à moitié l'anglais j'ai tout compris. Thank you !!!!
This is so incredibly helpful!!! ❤️❤️❤️ thank you so much 😊
Beautifully explained - thank you.
THANK YOU SO MUCH!!! I have a presentation tomorrow and this was the last thing I was uncertain about.
ABSOLUTE LEGEND
Thank you so much!!! You explained everything quickly and very well ❤
Very well explained. Thank you!
thank you so much for this simple explanaition
Whoa that relay protein animation was sick!!
How sweet u r and how perfect u explained it ❤
Thank you for this!!!
thankyou so much... i finally understood it
Been trawling the Wikipedia article trying to understand this, thank you
Thank you ❤
I’m using this info for my project... thxs a lot mr. Renfro , wouldn’t be here without you ‘:)
Same 😳
Same
Very well explained! Thank you!
you saved me... Thank you so much!!!
Well explained!!
Thank you❤️❤️
Amazing video
Thank you so much this was very helpful!!
EXCELLENT! Thank you!
thank you so much, I'll use these ideas for my project! I'm doing this in AP BIO
how brilliant and creative u are!!! ty alot n keeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeep this up
I was wondering what program do you use to make this video? We're doing a project in my AP Bio similar to this but with a different subject.
I just made it with powerpoint (and used the animations feature to make things move) and then recorded with screen-cast-o-matic (the free version)
I’m drunk and watching this and it’s making sense which is like a huge compliment
Thank you❤
thank you 👌💖
Thanks for explaination!
thank you so much!
Best explanation ❤️👏
Awesome!
Very helpful!!
Thank you so much! This really helped!
Now I can fully picture what on earth a Dimer is thank you
رحم الله والديج ❤️
I just want to say thank you 😊
I have been struggling to understand this and you just made it with four and a half minutes you should be my professor you would make a better job than he did
thank you I passed the test
Sorry but may I know if the individual polypeptide chains are quaternary before they come together or are they tertiary?
Thank you
Hi, thank you for this video. It was short, simple, and very clear. I had one question that I'm confused about. Do both binding sites need to be filled for RTK's to become dimerized? What would happen if only one binding site is filled and the other one isn't? Would that ligand detach or would it stay there until the other site is filled?
Shoutout to my Biology 1010 class at SLCC. I hope you all survive the course!!
Epic video
very well and simplest explaind mam😊❤
Very clear....
Wow ❤
Does every tyrosine kinase take phosphate from ATP present in cytoplasm or does only one of them when phosphorylation transfer phosphorous to a relative of tyrosine kinase colloquially, meaning that each one when phosphorylation transmits phosphorous to her sister and I think the first is correct, answer me please
Great video…… thanks
Dope
All kind of proteins in cell go through conformational changes or selective few??By the way,this video is cool!
only some of the proteins. such as calmodulin and Rb. Most of the protein, which act not as an inhibitor, activator or signaling will not change.
you may or may not have just saved my ap bio grade ty
What kind of program did you use to do the animation?
Power Point
You are the best ❤
good stuff
Nice
Thanks
thanks
Nice explanation
@@willaherold9027 what??
teaching BEd I have no idea how this got here!
Wow
How important is dimer formation? thx
Very good job i will Ask you for a minute when th groupe of six tyrosine phosporated so that give us Always a six cell respense if i am false please show me the correct answer thx again
can you please mention the reference
मैडम धन्यवाद आपका
I found you The best
receptor tyrosine kinases === binds Ligand ==> transient dimerization
eg. Insulin, GF
all you really have to know for exams
When does autophosphorylation occur?
Not sure...
@Poison yes autophosphorylation of β-subunits occur!
After binding of insulin and activation of tyrosine kinase receptor
Autophorylation occur when ATP gives one phosphate to a Tyrosine and attached itself to it in order for auto phosphorylation occurs for activation.
@@destinytristina2083 i passed the exam last year but thank you for the help regardless bro
your voice tho
What about it?
Toni Gray its cute
Hi sweet voice
I was thinking the same thing, she has a sexy voice
Thank you ❤