Thank you so much for all of this info!!! I'm just starting and curious if I take my pill in the morning with 2-4T Olive Oil, is that sufficient for absorbtion or do you need solid food with it as well?
I can't speak to your specific situation, and no one has specifically looked at olive oil, but 2-4T of olive oil is about 25-50g of fat, which one would expect is likely sufficient.
hi Dr, just started very low dose accutane and was wondering, if i take it at 5:00am one day, can i take it at 6:30am the nest day or does it have to be exactly at 5:00am everyday? I appreciate all of your content!
In general (not speaking to your specific situation), the most important thing in terms of timing of when to take isotretinoin is to make sure it is taken with a meal that has fat in it (to help with absorption; for Lidose/micronized isotretinoin this is less of an issue).
Isotretinoin can rarely cause a telogen effluvium like hair loss that often improves after stopping the medication. Some studies suggest that it is more common with higher dose regimens.
@@DrJohnBarbieri I started yesterday with isotretinoin 20mg/day, im going to add desloratadine 5mg/day to prevent the purge, how much time i need to take it?
@@DrJohnBarbieri I started yesterday with isotretinoin 20mg/day, im going to add desloratadine 5mg/day to prevent purge, how much time i need to take it? What other thing can i do to improve the acne remission in this treatmen with isotretinoin?
Hi, im taking isotretinoin 20mg/day, i started this week, im going to add desloratadine 5mg/day to prevent purge. How much time do i need to take desloratadine?
This channel is not for medical advice, so I would recommend discussing with your doctors. In the clinical trials, participants took the antihistamines for about 3 months.
I have been taking Accutane ( 10mg per day ) from last November to this year's August. My acne is cleared but should I continue to consume it for precaution?
This channel is not for personal medical advice, so I would suggest discussing with your doctor. In general, with isotretinoin, the goal is to achieve a long-term clearance, so typically we discontinue it once someone has had clear skin for >2-3 months and reached >120mg/kg of cumulative dose. About 60-80% of individuals with have no meaningful recurrence of acne after discontinuing isotretinoin.
I don't think the brand matters that much. For some who have trouble with absorption, using a Lidose isotretinoin (Absorica) or micronized isotretinoin (Absorica-LD) can be helpful and can make dosing more consistent. But I think most can do well with any formulation of isotretinoin (just might need a higher dose with standard isotretinoin).
If I was to need to switch to Accutane from doxycycline how long do you typically suggest you wait between medications? does it have to be 7 days? I am worried about breaking out in between ?
Yes, assuming it was otherwise the same formulation (i.e. need to consider that micronized isotretinoin has different dosing due to the improved absorption).
Although there is some uncertainty regarding whether isotretinoin is associated with inflammatory bowel disease or irritable bowel syndrome, high quality studies have not found an association between isotretinoin exposure and either inflammatory bowel disease or irritable bowel syndrome. Of note, oral antibiotics are an established risk factor for development of inflammatory bowel disease, so this must be kept in mind when considering treatment options (as well as when designing studies as it can be a confounding factor).
Accutane is the original brand (now left the market). Micronized isotretinoin is same drug, but better absorbed. It can be expensive, and unclear that it is meaningfully better than Lidose-isotretinoin.
It typically takes 5-8 months to complete a course of isotretinoin. Depending on acne severity and dosing regimen, it is not unusual for some acne to still be present until month 4-5 or later.
Please doctor reply me I'm currently on 20 mg isotretinoin per day I have mild to moderate acne ihave been taking it from 30 days i have no side effect only side effect i see some dryness over lips Nothing else But i sae on internet the low dose of isotretinoin is.5mg/kg Im 75 kg should i take 40 mg now Please doc my dermatologist is not good i have changed so many they all consult me just for 2-3min Please reply doc
No. In general, higher cumulative doses are associated with greater likelihood of long-term clearance, but some people need higher doses and some need lower doses. Achieving clear skin x2-3 months before stopping is a good predictor of long-term clearance.
Sir my demetrologist put me first 20 mg daily for 1 month after one month i get rare side effects pyogenic granuloma (PG). He say to stop taking isotretinoin for 2 weeks than i stopped. Again after consultation he recommended me 20 mg every other day it take 20 mg alternative day for 2 months. i had grade 3 acne after one month only my acne are stopped to come . After 20 mg alternative day he prescribed me 10 mg alternative day now . I have too much oily face my acne are too much recurrance before isotretinoin. After lowing my dose to 10 mg alternative day i see change on my face my acne hasn't come back but all oilness has come back acne also come 2,3 in a week . I don't know what to do and what my demetrologist is doing. Please advise me doctor??
Sorry to hear about these challenges. This channel is not for medical advice, so I cannot speak to your specific situation. You could share some of the references in the video with your dermatologist to see if that is helpful.
@DrJohnBarbieri I share him I don't know what type of demetrologist is him. My acne are flare up slowly my acne are coming on jawline. Demetrologist say to continue isotretinoin for 2 months 10mg alternative day than we should discontinued to used he say. Sir should I have to change my demetrologist or what
I was just looking for a Video about this topic! Thank you for educating is! 🎉
You are so welcome!
Very enlightening. Thank you!
Glad it was helpful!
Thank you so much for all of this info!!! I'm just starting and curious if I take my pill in the morning with 2-4T Olive Oil, is that sufficient for absorbtion or do you need solid food with it as well?
I can't speak to your specific situation, and no one has specifically looked at olive oil, but 2-4T of olive oil is about 25-50g of fat, which one would expect is likely sufficient.
@@DrJohnBarbieri Thank you so much for the response!
Very helpful! Thank you.
You're welcome!
Thank you for sharing Dr. please I have a question. Please can a Hepatitis B patient take Acnotin??
Isotretinoin is metabolized (cleared from the body) by the liver, so it should be used carefully in those who have liver disease.
hi Dr, just started very low dose accutane and was wondering, if i take it at 5:00am one day, can i take it at 6:30am the nest day or does it have to be exactly at 5:00am everyday? I appreciate all of your content!
In general (not speaking to your specific situation), the most important thing in terms of timing of when to take isotretinoin is to make sure it is taken with a meal that has fat in it (to help with absorption; for Lidose/micronized isotretinoin this is less of an issue).
Hello! What about hair loss with isotretinoin? And how to prevent it?
Isotretinoin can rarely cause a telogen effluvium like hair loss that often improves after stopping the medication. Some studies suggest that it is more common with higher dose regimens.
@@DrJohnBarbieri Thank you so much
@@DrJohnBarbieri I started yesterday with isotretinoin 20mg/day, im going to add desloratadine 5mg/day to prevent the purge, how much time i need to take it?
@@DrJohnBarbieri I started yesterday with isotretinoin 20mg/day, im going to add desloratadine 5mg/day to prevent purge, how much time i need to take it? What other thing can i do to improve the acne remission in this treatmen with isotretinoin?
Hi, im taking isotretinoin 20mg/day, i started this week, im going to add desloratadine 5mg/day to prevent purge. How much time do i need to take desloratadine?
This channel is not for medical advice, so I would recommend discussing with your doctors. In the clinical trials, participants took the antihistamines for about 3 months.
Can Isotretinoin cause chronic dry eye after treatment? (since it impacts the meibomian glands)
Check out this thread discussing the issue:
bsky.app/profile/drjohnbarbieri.bsky.social/post/3lcdqphkncs2k
@@DrJohnBarbieri Thanks for this resource!
I have been taking Accutane ( 10mg per day ) from last November to this year's August. My acne is cleared but should I continue to consume it for precaution?
This channel is not for personal medical advice, so I would suggest discussing with your doctor. In general, with isotretinoin, the goal is to achieve a long-term clearance, so typically we discontinue it once someone has had clear skin for >2-3 months and reached >120mg/kg of cumulative dose. About 60-80% of individuals with have no meaningful recurrence of acne after discontinuing isotretinoin.
Did you have bad side effects?? Like extreme dryness?? Please reply
@@Nreyab2006 not really. As I'm taking a low dose , I m only suffering from chapped lips. That's really about it.
What are your thoughts on different brand. I’m on 64 mg of Absorica LD with no progress
I don't think the brand matters that much. For some who have trouble with absorption, using a Lidose isotretinoin (Absorica) or micronized isotretinoin (Absorica-LD) can be helpful and can make dosing more consistent. But I think most can do well with any formulation of isotretinoin (just might need a higher dose with standard isotretinoin).
@@DrJohnBarbieri thanks. I have like no side effects despite a little dryness, do you think I should ask to go up past 64 daily after the month ends
@@anthonycareccia3488 how is it now
If I was to need to switch to Accutane from doxycycline how long do you typically suggest you wait between medications? does it have to be 7 days? I am worried about breaking out in between ?
Sorry, but this channel is not for medical advice. I would recommend discussing with your doctor.
Would you dose an oral liquid isotretinoin the same as tablets?
Yes, assuming it was otherwise the same formulation (i.e. need to consider that micronized isotretinoin has different dosing due to the improved absorption).
What about drying of the colon and ibs Dr.?? What does accutane do to peoples internal!!??
Although there is some uncertainty regarding whether isotretinoin is associated with inflammatory bowel disease or irritable bowel syndrome, high quality studies have not found an association between isotretinoin exposure and either inflammatory bowel disease or irritable bowel syndrome. Of note, oral antibiotics are an established risk factor for development of inflammatory bowel disease, so this must be kept in mind when considering treatment options (as well as when designing studies as it can be a confounding factor).
Hey... Today my skin doctor prescribed me micronized isotretinoin capsules 20mg .. Is this also called accutane??
Accutane is the original brand (now left the market). Micronized isotretinoin is same drug, but better absorbed. It can be expensive, and unclear that it is meaningfully better than Lidose-isotretinoin.
After 3 months I still get some little break out here and there, is it normal
It typically takes 5-8 months to complete a course of isotretinoin. Depending on acne severity and dosing regimen, it is not unusual for some acne to still be present until month 4-5 or later.
It’s been 1 and half months on accutine . But i am not seeing much progress. What should i do now?( I am taking 20mg per day)
I cannot comment on what is best for you (you should discuss with your doctor). In general, a treatment course of isotretinoin is at least 5-8 months.
Check with your doctor about increasing it.
Please doctor reply me
I'm currently on 20 mg isotretinoin per day I have mild to moderate acne ihave been taking it from 30 days i have no side effect only side effect i see some dryness over lips Nothing else But i sae on internet the low dose of isotretinoin is.5mg/kg Im 75 kg should i take 40 mg now Please doc my dermatologist is not good i have changed so many they all consult me just for 2-3min
Please reply doc
Sorry, this channel is not for medical advice so I cannot tell you what to do for your acne. You are correct that
To permanently cure acne 120mg per kg cummalative dose necessary for everyone ?
No. In general, higher cumulative doses are associated with greater likelihood of long-term clearance, but some people need higher doses and some need lower doses. Achieving clear skin x2-3 months before stopping is a good predictor of long-term clearance.
@@DrJohnBarbieri and what type of blood test is done while on Accutane i mean what elements are essential in the report
Sir my demetrologist put me first 20 mg daily for 1 month after one month i get rare side effects pyogenic granuloma (PG). He say to stop taking isotretinoin for 2 weeks than i stopped. Again after consultation he recommended me 20 mg every other day it take 20 mg alternative day for 2 months. i had grade 3 acne after one month only my acne are stopped to come . After 20 mg alternative day he prescribed me 10 mg alternative day now . I have too much oily face my acne are too much recurrance before isotretinoin. After lowing my dose to 10 mg alternative day i see change on my face my acne hasn't come back but all oilness has come back acne also come 2,3 in a week . I don't know what to do and what my demetrologist is doing. Please advise me doctor??
Sorry to hear about these challenges. This channel is not for medical advice, so I cannot speak to your specific situation. You could share some of the references in the video with your dermatologist to see if that is helpful.
@DrJohnBarbieri I share him I don't know what type of demetrologist is him. My acne are flare up slowly my acne are coming on jawline. Demetrologist say to continue isotretinoin for 2 months 10mg alternative day than we should discontinued to used he say. Sir should I have to change my demetrologist or what
Load up on 40mg/kg per day for 6 months and say 👋 to acne for good!
Thanks for watching!
Bhai i am 19 and suffering from acne from last three years , should i go for high dose or not
For adult acne, it will inevitably return. No permanent cure for adult acne