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Singular Genomics
United States
เข้าร่วมเมื่อ 30 พ.ย. 2020
We are taking sequencing further to bring you fast, powerful and flexible tools for research and precision medicine. Our aim is to empower scientists to answer their most pressing questions, allowing them to forge a path of discovery without limits.
Labroots Webinar | Enabling Spatial Biology at Scale with In-Situ Sequencing on the G4X
In-situ multiomics is revolutionizing research in oncology, immunology and neurobiology. However, speed and throughput are major bottlenecks for these critical studies. Here, we present data from a novel in-situ sequencing system, with sub-micron resolution and ultra-high throughput capacity, employing rapid 4-color SBS chemistry to profile RNA transcripts and proteins in FFPE tissue. The system also generates virtual H&E images, producing multi-modal spatial images of 40 cm2 of tissue in less than 24 hours.
มุมมอง: 847
วีดีโอ
Singular Genomics AACR 2024 Presentation by Eli Glezer, PhD | In-Situ Sequencing
มุมมอง 6226 หลายเดือนก่อน
In-situ multiomics is revolutionizing research in oncology, immunology and neurobiology. However, speed and throughput are major bottlenecks for these critical studies. At the American Association for Cancer Research (AACR) Annual Meeting 2024, our CSO and Co-founder, Eli Glezer, PhD., presented data from G4X, a novel in-situ sequencing system, with sub-micron resolution and ultra-high throughp...
In Situ Sequencing: Enabling Spatial Biology at Scale
มุมมอง 7198 หลายเดือนก่อน
At AGBT 2024, our CSO and Co-Founder, Eli Glezer, covered several exciting updates. Topics include the introduction of the G4X Spatial Sequencer and its unprecedented high-throughput multiomic readout capabilities, G4X performance and collaboration data, and development of the higher throughput F4 flow cell and its addition to the G4 product offering.
Singular Product Premiere | A New Era of Spatial Discovery
มุมมอง 5738 หลายเดือนก่อน
Spatial biology research faces critical limitations, such as high costs, constrained throughput, and extensive turn-around times. Tune in to our product premiere as we introduce a new era of high-throughput spatial multiomics with CEO, Drew Spaventa, and CSO, Eli Glezer.
Ultra Low-Diversity Sequencing on the G4
มุมมอง 729 หลายเดือนก่อน
Leading scientists Ann Tong and Chrystal Day delve into the performance of low-diversity sequencing on G4. They address the challenges faced by traditional sequencing platforms and demonstrate how G4 presents an effective, cost-efficient alternative using three case studies, offering a thorough understanding of the impact of G4.
Under the Hood of Genomics | Eli Glezer, PhD. Keynote at Festival of Genomics, Boston 2023
มุมมอง 498ปีที่แล้ว
Tune in to Singular Genomics CSO and Founder, Eli Glezer, PhD.'s keynote presentation at Festival of Genomics, Boston 2023, where he highlights some of the unique ways to read DNA, the progress made in designing and building a DNA sequencer, and applications of sequencing beyond the genome. Singular Genomics is on a mission to accelerate genomics for the advancement of science and medicine. Foc...
Metagenome Sequencing on the G4 Sequencing Platform
มุมมอง 106ปีที่แล้ว
Two key challenges of NGS-based microbiome analysis are the presence of high and low GC content organisms and batching-related delays. Join Bubba Brooks, our Staff Scientist of Bioinformatics, as he highlights the benefits of the flexibility and speed of the G4 Platform for microbial analysis, in addition to discussing results compared to the NextSeq 2000. The G4 Sequencing Platform empowers la...
Singular Genomics G4 Sequencing Platform Workshop and Q&A | ESHG 2023
มุมมอง 760ปีที่แล้ว
In this presentation at the ESHG Conference, Darius Fugere and Dr. Timothy Looney highlight the capabilities of the G4 Sequencing Platform, a benchtop sequencer combining a novel 4-color Rapid sequencing by synthesis (SBS) chemistry with sophisticated optics and fluidic engineering. Designed to overcome the hurdles of traditional NGS systems, such as lengthy analysis times and high costs, the G...
Rapid Targeted Germline and Somatic Variant Detection Using The G4 Sequencing Platform
มุมมอง 49ปีที่แล้ว
In this webinar, Dr. Timothy Looney, Senior Director of Scientific Affairs at Singular Genomics, introduces the G4 sequencing platform's capabilities for rapid germline and somatic variant detection. He highlights the platform's compatibility with numerous library preparation partners and the benefits of using GPUs for bioinformatics acceleration. Dr. Looney presents data showcasing the G4 plat...
Singular Genomics Support and Customer Care
มุมมอง 145ปีที่แล้ว
Meet Laure Moller, the VP of Customer Solutions & Support at Singular Genomics. At Singular Genomics, customer care is not just a department - it’s a core principle that drives our business. When you call Singular Genomics, be assured that you will receive a solution to your issue, an answer to your question, and that your concerns will be addressed with utmost priority. Laure and her team ensu...
Ron Graham - Senior Director of Chemistry | Minds Behind The Design
มุมมอง 107ปีที่แล้ว
Join us on an epic scientific journey with Ron Graham, Distinguished Fellow and Senior Director of Chemistry at Singular Genomics. Ron describes the thrill of discovery as akin to being the first person to walk on the moon. Every new reversible terminator nucleotide developed by his team heralds a groundbreaking step towards the future of genomics. In the early days at Singular Genomics, a smal...
We Are Singular | Our Story
มุมมอง 526ปีที่แล้ว
Delve into the culture, mission, and innovative work at Singular Genomics. Driven by a vision to accelerate medicine through advanced sequencing technologies, we discuss how Singular Genomics was built from the ground up with a keen focus on innovation and collaboration. Our G4 sequencing platform reflects our commitment to pushing the boundaries of technology and science. With a culture rooted...
Trevor Vogt - Optical Systems Engineer | Minds Behind The Design
มุมมอง 251ปีที่แล้ว
Meet Trevor Vogt, an Optical Systems Engineer at Singular Genomics. Trevor's role involves working on the optical, electrical, and mechanical subsystems within the G4 Sequencing Platform. His specific focus has been on the optical sensing of fluids within the channels of the machine. Trevor's work process involved a prototyping and design phase where he created a novel concept. After prototypin...
G4 Overview | G4 Sequencing Platform Support
มุมมอง 344ปีที่แล้ว
This video gives an in-depth overview of the G4 Sequencing Platform's components. The intuitive touchscreen display interface and color-coded indicator strip are featured, as well as the three accessible compartments: the buffer, reagent, and flow cell compartments. We explore the specifics of each compartment, from housing the waste reservoir and wash cartridges, loading the pre-filled reagent...
How to Prepare Your Library For Loading | G4 Sequencing Platform Support
มุมมอง 138ปีที่แล้ว
This video presents a comprehensive guide on preparing libraries for loading on the G4 Sequencing Platform. It elaborates on the three-step process involving denaturation, neutralization, and final sample dilution. Detailed instructions are provided on how to accurately dilute your library and how to achieve the correct final sample concentration. The G4 Sequencing Platform empowers labs with u...
How to Load Samples in The Sample Cartridge | G4 Sequencing Platform Support
มุมมอง 156ปีที่แล้ว
How to Load Samples in The Sample Cartridge | G4 Sequencing Platform Support
How to Use Custom Primers | G4 Sequencing Platform Support
มุมมอง 124ปีที่แล้ว
How to Use Custom Primers | G4 Sequencing Platform Support
How to Prepare Reagent Cartridges | G4 Sequencing Platform Support
มุมมอง 119ปีที่แล้ว
How to Prepare Reagent Cartridges | G4 Sequencing Platform Support
Preparing For a Run | G4 Sequencing Platform Support
มุมมอง 192ปีที่แล้ว
Preparing For a Run | G4 Sequencing Platform Support
Handling and Loading Flow Cells | G4 Sequencing Platform Support
มุมมอง 179ปีที่แล้ว
Handling and Loading Flow Cells | G4 Sequencing Platform Support
How to Dispose of a Used Reagent Cartridge | G4 Sequencing Platform Support
มุมมอง 141ปีที่แล้ว
How to Dispose of a Used Reagent Cartridge | G4 Sequencing Platform Support
How to Dispose of Waste on the G4 Sequencing Platform | G4 Sequencing Platform Support
มุมมอง 60ปีที่แล้ว
How to Dispose of Waste on the G4 Sequencing Platform | G4 Sequencing Platform Support
Revolutionizing NGS: Exploring the Fast and Cost-Efficient G4 Platform with Dr. Timothy Looney
มุมมอง 138ปีที่แล้ว
Revolutionizing NGS: Exploring the Fast and Cost-Efficient G4 Platform with Dr. Timothy Looney
Behind the Design | G4 Sequencing Platform
มุมมอง 7682 ปีที่แล้ว
Behind the Design | G4 Sequencing Platform
Delivering Fast, Flexible Next Generation Sequencing | Labroots Webinar
มุมมอง 3732 ปีที่แล้ว
Delivering Fast, Flexible Next Generation Sequencing | Labroots Webinar
G4 Sequencing Platform | Innovation with Intention
มุมมอง 1.3K2 ปีที่แล้ว
G4 Sequencing Platform | Innovation with Intention
1. What is value in such massive amount of data. The more is always better, but it could be confusing as well 2. Can the data be referenced to existing standards. 3. Since the dataset has many dimensions for human brain could you use it to train AI for help? It is powerful platform, but seems to be nice for power-point, but a long term research project
You guys should post more on TH-cam and all socials! Great stuff.
This is next level technology congratulations on your success.
What products will be made from this material? Maybe lightweight transportable electric wheelchairs?
Fantastic presentation.
Millennials.. as 3CPO Said.. Were domed..
The 7th person has the energy to last all day.
Amazing technology, the market needs this!