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Cyperus Oil - Is it SAFE? | Toxicologist answer
Well, hello! I'm Mo, a toxicologist and risk assessor. In today's video, I delve into the safety of Cyperus oil-the viral sensation touted as a natural hair removal miracle. But is it really safe to use? Should you be applying it to your skin?
With limited data available, I conducted my own safety assessment focusing on hazard identification and exposure risk. Using molecular docking software and skin absorption models, I analyzed the main compounds in Cyperus oil-Cyperene and β-Selinene-to see how they interact with the body's androgen receptors and whether they can penetrate the skin to reach systemic circulation.
What I discovered raises important concerns about the potential health risks associated with this oil, including possible implications for hormonal balance and even cancer risk. I also discuss why it's crucial to critically evaluate advice from online influencers and understand the science behind products before using them.
Join me as I break down the findings of my three-week investigation, explaining each step in accessible terms. By the end of this video, you'll have a clearer understanding of whether Cyperus oil is a safe choice for you.
I want to thank and credit @LabMuffinBeautyScience for our discussion regarding cancer induction
TIMESTAMPS:
00:00 intro
00:13 Efficacy
00:31 This Oil lacks safety Data
00:45 How is risk assessment conducted by Toxicologists?
03:27 First step of my risk assessment - what's inside this oil?
04:54 Hazard assessment of the components
06:04 Limitations of my Hazard assessment.
07:26 Can those components get inside your skin?
11:26 Limitations of my exposure assessment
13:01 The risk of cancer induction
15:54 My final conclusion
16:36 Important lessons we can learn from this.
References:
DOI:10.1080/10412905.2005.9699035
Doi: 10.3390/molecules14082909
DOI: 10.9734/sajrm/2020/v7i130159
DOI:10.24092/CRPS.2017.070102
Doi: 10.3389/fmolb.2021.716466
DOI: 10.1016/0045-6535(95)00023-2
DOI: 10.1177/1090820X13518801
DOI: 10.1016/j.yrtph.2007.12.006
Doi: 10.3389/fendo.2018.00492
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มุมมอง: 1 191

วีดีโอ

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ความคิดเห็น

  • @lonewolf5969
    @lonewolf5969 9 ชั่วโมงที่ผ่านมา

    What brand were you using?

  • @kariboudreaux6738
    @kariboudreaux6738 21 ชั่วโมงที่ผ่านมา

    Experts out of their field of expertise lol.

  • @Al_ate_my_soup
    @Al_ate_my_soup 3 วันที่ผ่านมา

    I am disappointed but not surprised. Perhaps the compounds will be isolated and the research that comes out of it will result in safe products to be used for hair growth reduction, here’s to hoping! Edit: Can you look into tiger nut oil next? I saw some people recommending it for the same purpose of slowing hair growth, looking at a meta analysis about it briefly it seems as though it’s pretty different chemically than Cyperus oil so I’m interested to know the potential toxicity from your perspective. Honestly probably a silly question since it’s edible, but I’d still like to hear your thoughts or how exactly it may work.

  • @cristinarugo7529
    @cristinarugo7529 3 วันที่ผ่านมา

    Thanks for your professional answers. I would like to have more data either mostly about what happen during the time spicules remain on the skin before they go away with dead cells..do they cover too much the skin? Or they may occlude pores?

  • @vanshikapun298
    @vanshikapun298 3 วันที่ผ่านมา

    Which one is best for sunburn??

  • @ShirleyValentine-st3qg
    @ShirleyValentine-st3qg 4 วันที่ผ่านมา

    Thank you for sorting wheat from chaff for us.

  • @rishitapanchaljani548
    @rishitapanchaljani548 4 วันที่ผ่านมา

    Hi Mo! I am here from Dr Wong’s TH-cam video, debunking the myth of a video of a toxicologist on the channel of Diary of a CEO. Thank you for explaining things so succinctly in your video! Commenting so your videos get more reach. Thanks for doing this :)

  • @reww0000
    @reww0000 4 วันที่ผ่านมา

    Thank you so much brother❤❤

  • @titaniumhexafluoride5138
    @titaniumhexafluoride5138 4 วันที่ผ่านมา

    This side of TH-cam is.....❤

  • @cupcakeladyattie2578
    @cupcakeladyattie2578 4 วันที่ผ่านมา

    MashaAllah, lab muffin mentiond you. Good work brother

  • @swaydutwa9596
    @swaydutwa9596 4 วันที่ผ่านมา

    Really appreciate you putting all this together! When I first heard the claims, I was skeptical. Seeing your videos on the topic (and the controversy, oh my!), was super helpful. Thank you!! - signed, new subscriber

  • @S0dap0pb0ttle
    @S0dap0pb0ttle 5 วันที่ผ่านมา

    Thanks for making this video! I hope you have a chance to review the toxicologist interview from the diary of a CEO :) I feel like she is truly trying to do whats best but might be jumping the gun on some accusations as there needs to be a lot more research. She might feel super justified bc she deduced that toxins were the cause for her infertility and doesn't want others to experience that harm, which I get, but her science seems clouded. It's hard to see nuance when you've been personally affected and are trying to save others. For example, she acknowledges that there needs to be more research, but continues to make suggestions and seems to imply that if we find correlation, it's proof of causation. I'd love to see where you agree and disagree with her. I was pretty surprised she didn't talk about the pollution of gas stoves, which I'd think is the #1 pollutant at home. Maybe she did and I just missed it

  • @kennethAmos8929
    @kennethAmos8929 5 วันที่ผ่านมา

    Interesting and in a way fascinating

  • @annafilban2859
    @annafilban2859 5 วันที่ผ่านมา

    Thank you. Very informative! Is this ingredient on the product label listed beneath active or inactive ingredients?

  • @Efeste.ban.
    @Efeste.ban. 5 วันที่ผ่านมา

    Who’s here from LabMuffinBeauty 😃

  • @venlanen
    @venlanen 5 วันที่ผ่านมา

    Commenting for the algorithm

  • @noxyglow2363
    @noxyglow2363 6 วันที่ผ่านมา

    I just used Uriage and it gave me a tingle, as long as I Don breakout I am kool. I normally use La roche possay

  • @JillKnapp
    @JillKnapp 6 วันที่ผ่านมา

    This is a fantastic video with great information. Science FTW! Michelle from Lab Muffin told her viewers about your channel-- very happy to be here. 🙂

  • @AyAReI00
    @AyAReI00 6 วันที่ผ่านมา

    Yeah i dont care if is natural, if a sustance has this absorption and potencial of system distribution withouth having proper studies to back it up , is scary. Thanks for doing all this hard work, i dont like magical compunds that come from no where, also is kind of dissapointing seeing a doctor with a huge platform suggesting the use of chemicals withouth backing

  • @vanbriannemodel
    @vanbriannemodel 8 วันที่ผ่านมา

    Thankfully, I saw yours and lab muffins posts. I ordered this oil because a certain dermatologist said there was no harm in trying it. Meanwhile, I’ve been going through hormone positive breast cancer treatment for the last two years. And I was about to start slathering this “Non-harmful” oil all over my skin every day when I’m supposed to be suppressing my 100% estrogen and progesterone positive breast cancer. Had I not known and started using this regularly there was a possibility of my cancer coming raging back at stage four and giving me a death sentence. And I don’t care how high or low that possibility was, it’s certainly not worth it. The unopened oil just went into the garbage where it belongs. Thanks to you and lab muffin for potentially saving my life! And there’s one more TH-cam influencer I no longer trust. But you have a new follower in me, and my own TH-cam channel Chronicles my breast cancer journey completely uncensored through every step of the process. Once I edit and upload a few more videos, the moderators in the many breast cancer forums will officially launch my channel and be posting and offering my channel as a resource for other women in the forums who need support and guidance. And now I plan to do a specific video on the dangers of Cyprus oil, and I hope it is alright if I leave a link to your video. I think that especially women with breast cancer or who have had breast cancer absolutely need to know this information since this oil has gone viral. Once again, you have my deepest respect and thanks ❤

  • @TapaswiniSwain
    @TapaswiniSwain 9 วันที่ผ่านมา

    Thanks for all the good work 👏

    • @Moskinlab
      @Moskinlab 7 วันที่ผ่านมา

      Thank you too!

  • @hhspore
    @hhspore 9 วันที่ผ่านมา

    very clear. upfront and unbiased review. great content. I have subscribed to your channel to get more useful information. Thank you !

  • @rachelbloom1946
    @rachelbloom1946 9 วันที่ผ่านมา

    I used it once and am now paranoid. I threw it out. Would the risk be fairly low for one time use? I also applied after using an essence so hope that buffered

  • @alessandrashipman7477
    @alessandrashipman7477 10 วันที่ผ่านมา

    I loved seeing the tools and software you used to model potential hazards and absorption! Thank you for this peek behind the curtain!

  • @mybijoubox
    @mybijoubox 10 วันที่ผ่านมา

    Thank you for all your research and for using your expertise to find out its potential risks 👨‍💻 Commenting for the algorithm too; this vid needs more views!

  • @alicekravets8584
    @alicekravets8584 10 วันที่ผ่านมา

    The “everything is full of toxic chemicals” crowd when they see an essential oil with shady studies behind it:😩🥴🥰🙂‍↕️💦

  • @alicekravets8584
    @alicekravets8584 10 วันที่ผ่านมา

    You did a very good job and it is wild that this video doesn’t have more views. Comment for the god of algorithms

  • @farahdibasonda6708
    @farahdibasonda6708 13 วันที่ผ่านมา

    Great job Mo! Can't praise you enough for the amount of work you have done to bring such in-depth information to us!

  • @nadab4750
    @nadab4750 14 วันที่ผ่านมา

    Hi Mo, I also encourage you to look at this ABC News (Australia) report... I don't want to insert a link, but just Google this..."'Unbelievable': Oncologist questions claims of 'doctor' lauded by Elle Macpherson". Especially, as this 'doctor' has made claims of being a toxicologist . This exposé came out only days after I was sick of getting pop-up ads for Elle Mc Pherson's 'wellness' drink; and I (out of curiosity & healthy suspicion) wanted to see what she was spruking, so looked at the website. At first I was laughing at the poorly written content etc. I then showed my partner and told him that the algorithms couldn't be more wrong to think that I would be interested in this. My laughter then turned to anger when I saw that it was making all these product claims, including having health benefits "against all odds"! What...against science?! A few days later my partner asked me whether I had told ABC news about this (which I actually hadn't), as he saw that coincidentally the ABC were doing an indepth report into this product; and Elle Mc Pherson's 'doctor' friend, who she enlisted to give supposed credibility to her 'wellness' drink brand. Elle Mc Pherson became famous in Australia as a young model wearing a red bikini in a "Tab" diet drink TV commercial. Perhaps wearing a "red flag" may be more appropriate this season? Congratulations Mo & Michelle for dedication to science & integrity. I always knew that both of you weren't just pretty faces! 👱❤️

  • @lucyfoskett2567
    @lucyfoskett2567 14 วันที่ผ่านมา

    Thank you so much for your hard work putting this together. I am so annoyed that I purchased the oil thinking the recommendation was reliable. Luckily it took a while to be delivered so I saw yours and Michelle's concerns before receiving it. It's going in the bin now. What a waste of money and resources.

  • @czarinabeautyhome
    @czarinabeautyhome 14 วันที่ผ่านมา

    Thanks Mo! You're an amazing person. Your effort towards educating people is appreciated! Thank you🎉

  • @escape2064
    @escape2064 15 วันที่ผ่านมา

    u r sooooooo beautiful

  • @christian_k_e
    @christian_k_e 15 วันที่ผ่านมา

    I know you are a Master Student, and I don't know you so don't take my opinion with too much weight, but I believe you should think about pursuing a PhD in Chemistry/Toxicology/Pharmacy. The work you have done, in only three weeks is unbelievable. Amazing video!

    • @Moskinlab
      @Moskinlab 15 วันที่ผ่านมา

      Thank you so much christian for your kind words, i graduated from my masters last year and currently working as a researcher, to be honest with you i don’t know if i still have the energy or the time to pursue a PhD, maybe id i get a perfect opportunity i may change my mind who knows, again thank you and appreciate you enjoying the video.

  • @michellequezada7902
    @michellequezada7902 15 วันที่ผ่านมา

    Hi Mo! Thank you for the video, I was waiting for your assessment about those viral videos. It really makes me sad that medical doctors are taking obviously low quality studies to try to sell these things and even more so saying that is more effective than the current acceptable treatments, those people are even trained in Ivy League unis in the US and I 100% think they know what they are doing (specially her that has a skincare brand). People think essential oils are this innocuous elements when they are not. I have seen a case report (haven't read the complete article) about a possible association of lavender essential oil use and precocious puberty in children, both girls and boys due to estrogenic effects in breast tissue. It would be interested if you could assess this also (although is a really long process) because your input is really necessary with all this 'clean beauty' trends that sells really expensive products with multiple essential oils. 😄

  • @bodorkanadil3143
    @bodorkanadil3143 15 วันที่ผ่านมา

    ❤❤❤❤

    • @Moskinlab
      @Moskinlab 15 วันที่ผ่านมา

      ❤️❤️❤️

  • @ocskinlab9440
    @ocskinlab9440 15 วันที่ผ่านมา

    This was amazing! Thank you for your hard work and dedication to science in skincare 🙏✨️

    • @Moskinlab
      @Moskinlab 15 วันที่ผ่านมา

      I am so glad you enjoyed it, thank you for watching

  • @Lehanorah1918
    @Lehanorah1918 15 วันที่ผ่านมา

    This is remarkable - an incredible amount of work 👏🏼👏🏼 💕 Before the vid popped up, I'd found one paper (seemed to a lay-person a half-decent trial),comparing it's efficacy for hyperpigmentation,compared to hydroquinone(plus a placebo group ) ....other than that,a few random online groups extolling its virtues as a 'natural' 😕 hair remover ( I was *trying* to find out what on earth was doing the work in an oil that would make your body hair fall out ... I couldn't find any proper answer,so I just concluded that whatever it was, it's probably not good 😊) . Thank you so,so much ✌🏼💕

    • @Moskinlab
      @Moskinlab 15 วันที่ผ่านมา

      Thank you so much, yes that paper if i am not mistaken is by the same author, it’s an attempt by that author to really glamorise that oil benefits. Most likely it’s just an oil that have a risk that need more investigation and no solid evidence for efficacy 😊

  • @megschield8412
    @megschield8412 15 วันที่ผ่านมา

    Thank you for the deeper dive into Cyprus oil Mo! Let's just say I no longer follow certain a dermatologist 😊

    • @Moskinlab
      @Moskinlab 15 วันที่ผ่านมา

      My pleasure and thank you watching 😊

  • @corinastoian3801
    @corinastoian3801 15 วันที่ผ่านมา

    So much work and so much to consider! Very nice, thank you for this video!

    • @Moskinlab
      @Moskinlab 15 วันที่ผ่านมา

      My pleasure 😇 and thank you for watching

  • @rubysresource
    @rubysresource 15 วันที่ผ่านมา

    I've been very excited for this video! It's so frustrating how people assume natural extracts are safe without proper saftey data. Thank you so much for all the time and effort you put into this, I appreciate it greatly!

    • @Moskinlab
      @Moskinlab 15 วันที่ผ่านมา

      Thank you so much Ruby, I totally share your frustration and sometimes it feels depressing trying to undo the damage that some just do with 5 sec video

  • @PaigeEscapes
    @PaigeEscapes 15 วันที่ผ่านมา

    Thank you Mo- this was truly incredible. All the research and work you have done putting this together was amazing and greatly appreciated. You presented the information perfectly and so happy to have this knowledge. Thank you so much Mo

    • @Moskinlab
      @Moskinlab 15 วันที่ผ่านมา

      Thank you so much for the kind words and support always Paige

  • @alinebraga6556
    @alinebraga6556 15 วันที่ผ่านมา

    Thank you for clarifying this topic

    • @Moskinlab
      @Moskinlab 15 วันที่ผ่านมา

      My pleasure 😇

  • @AllyGray
    @AllyGray 15 วันที่ผ่านมา

    I’ve never heard of this. Does this work mechanically or chemically?

  • @blah914
    @blah914 18 วันที่ผ่านมา

    i use skin oil in daily skin care, so ive switched out my regular one with this one to see what happens. its cheaper than my regular skin oil and smells very little, so its a zero sacrifice for me to try. if it works for its fabolous claims remains to see, but so far: it absorbs well, and quickly, doesnt leave much of a residue, and is excellent under makeup. as for anything else, i guess I'll see when im done w the bottle 🤷‍♀️

  • @_mayumi_
    @_mayumi_ 19 วันที่ผ่านมา

    Thank you for sharing your thoughts with us. It's always a good thing to learn as much as we can before we try a new product. I have seen a lot of positive reviews on the product and I must admit that it's tempting but I was asking myself how long I should be using it to maintain the results and what it's going to be like years down the road. It's a fairly new product and I have yet to find long time users who can talk about it so I'm not hopping on that train just yet.

  • @JohnnyBg2905
    @JohnnyBg2905 19 วันที่ผ่านมา

    Is the amount you applied enough for the half of the face in single application?

  • @px6329
    @px6329 20 วันที่ผ่านมา

    Will this help with pitted scars like Normal microneedling devices?

  • @akın_çana
    @akın_çana 21 วันที่ผ่านมา

    my bad, never read the label, thought that was glycolic acid when i buy, that’s however worked on me twice a week/ sunscreen 50spf always, but now with your video i understood why i should use heavier moisturiser 🥲 u re more informative than the brand!! ❤

  • @vitoria.yt.c
    @vitoria.yt.c 21 วันที่ผ่านมา

    😯

  • @slikjmuzik
    @slikjmuzik 25 วันที่ผ่านมา

    Why is nobody talking about the A-Game 20? I was able to handle the Ordinary Retinal 0.2% Emulsion every night after only 1 bottle of their Granactive Retinoid Emulsion, but the retinal is too small and I went through it too quickly, so I switched to the G&G A-Game 20 and haven’t looked back. Great product! This is the one you should be using if you came from tretinoin. The A-Game 10 pretty much anyone can use, it’s literally half as strong as the 20.