Maria Conley MD
Maria Conley MD
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Following Your Body's Circadian Rhythm: A Look at the Master Clock in the Suprachiasmatic Nucleus
A practicing board-certified internal medicine physician talks about how a group of approximately 20,000 neurons located in the center of your brain act as your body's master circadian clock. These neurons receive information about ambient light from your retina and then use this information to synchronize timekeeping in the cells of your liver, pancreas and adrenal glands, to name a few organs. The master clock in your suprachiasmatic nucleus is also responsible for the predictable daily rhythm in hormone levels, body temperature and body functions.
มุมมอง: 171

วีดีโอ

Fat Mass Regulation: Building Fat vs. Burning Fat and When Fat Goes Bad
มุมมอง 2472 หลายเดือนก่อน
A board-certified practicing internal medicine physician talks about how your body regulates fat mass. It's a balance between building more fat (via an enzyme called lipoprotein lipase) and burning fat (facilitated by another enzyme called hormone sensitive lipase). When too much fat builds up, your body runs out of storage space and deposits the fat cells in organs like the liver. At this poin...
Can Tattoos Cause Cancer?
มุมมอง 1914 หลายเดือนก่อน
A board-certified internal medicine physician discusses new data linking tattoo ink with lymphoma, or cancer of blood cells. Tattoo ink is largely unregulated and has been shown to contain cancer- causing chemicals such as polycyclic aromatic hydrocarbons. After tattooing, these carcinogens can travel to your lymph nodes where they can remain for a lifetime.
Where You Store Your Fat Matters
มุมมอง 7415 หลายเดือนก่อน
A board-certified internal medicine physician discusses why it's not just HOW much fat you have but WHERE it is stored in your body. Fat stored inside the abdomen (visceral fat) is more likely to cause diabetes than fat stored just underneath the skin (subcutaneous fat). Your age, sex and ethnicity determine where your fat will be stored.
How Severe Aortic Stenosis Causes Heart Failure
มุมมอง 3087 หลายเดือนก่อน
A board-certified internal medicine physician describes how a severely tight aortic valve (severe aortic stenosis) can cause heart failure if it is not replaced in time. Aortic stenosis is the most common problem affecting heart valves, occurring in about 3% of all people over age 75. Once you have been diagnosed with mild aortic stenosis, the valve inevitably gets tighter over time and a new v...
Aortic Stenosis: When Your Oxygen Delivery Valve Fails
มุมมอง 1699 หลายเดือนก่อน
A board-certified internal medicine physician discusses calcific aortic stenosis (tightening of the aortic valve), how it develops and why it is a problem. This is a common heart valve disease, especially if you are over 75. A tight aortic valve can cause trouble breathing or chest pain because your body may not be able to get enough oxygenated blood. A working aortic valve is critical to deliv...
How Much Alcohol Can I Drink Safely? The Calculated Risk of Drinking a Toxin and Carcinogen
มุมมอง 17211 หลายเดือนก่อน
A board-certified internal medicine physician discusses how alcohol intake can be considered as a calculated risk. Alcohol (technically ethanol) is the most common toxin and carcinogen that humans drink voluntarily. A potential benefit is the short-term upregulation of endorphins, GABA and serotonin, potentially causing feelings of relaxation and sociability. On the flip side, drinking any amou...
Muscle Regeneration After Injury: How the Satellite Cell Builds New Muscle
มุมมอง 817ปีที่แล้ว
A board-certified internal medicine physician explains how skeletal muscle is able to repair itself after exercise. One of the primary orchestrators of this process is the satellite cell, otherwise known as the adult stem cell of muscle. The ability of skeletal muscle to regenerate makes it possible to build new muscle at ANY age.
Adult Hippocampal Neurogenesis Explained in 3 Minutes
มุมมอง 1.4Kปีที่แล้ว
You are able to grow new brain cells throughout your life in the hippocampal formation of your brain. Certain activities such as running and learning new things can trigger this process. We'll follow a newborn neuron (brain cell) from its creation at Day 1 to the time it becomes a mature neuron at Day 60. Explained by a practicing board certified internal medicine physician.
Hitting the Triple G Spot: The New Triple G Agonist for Weight Loss
มุมมอง 3.8Kปีที่แล้ว
A practicing internal medicine physician talks about the new "G receptor" agonist weight loss medications semaglutide (Ozempic, Wegovy), tirzepatide (Mounjaro) and the latest drug in the pipeline retatrutide. We'll see how retatrutide, a so-called "triple G agonist" may be the most effective weight loss medication of all. By adding the combined hormonal effects of GLP-1, GIP and glucagon, retat...
How Running Slows the Aging of Your Brain
มุมมอง 682ปีที่แล้ว
A practicing internal medicine physician talks about how running slows the age-related shrinkage of the hippocampus, an area of your brain critical for memory. We will also see how brain-derived neurotrophic factor (BDNF) catalyzes the formation of new neurons and synapses.
Running Makes Your Brain Work Better: The Role of Neurotrophic Factors
มุมมอง 1.1Kปีที่แล้ว
A board-certified internal medicine physician discusses how proteins called neurotrophic factors affect how your brain functions. We'll see how the most famous neurotrophic factor BDNF (brain-derived neurotrophic factor) is upregulated during running. Ultimately, running throughout your life can help preserve and enhance cognitive function and BDNF is one mechanism behind this benefit.
GLP-1: The Weight Loss Molecule
มุมมอง 4.3Kปีที่แล้ว
A board certified internal medicine physician explains how two of the most effective weight loss strategies today the medication semaglutide (Ozempic) and weight loss surgery work by increasing the level of GLP-1 in your body. GLP-1 travels in your gut-brain axis via your bloodstream or by activating your vagus nerve. It works as a hormone and as a neuromodulator to change the way you think abo...
Adult Hippocampal Neurogenesis: Growing New Brain Cells as an Adult
มุมมอง 12Kปีที่แล้ว
A board certified internal medicine physician talks about how your adult brain creates new brain cells in a process called adult hippocampal neurogenesis. Certain activities such as running and learning a difficult task can trigger even more neurons to be created.
Hippocampus, the Seahorse in your Brain: Where Neurons are Born
มุมมอง 759ปีที่แล้ว
A board certified internal medicine physician talks about the hippocampus (Latin for "seahorse"). This is a small area of your brain that is critical for forming new memories. It shrinks with age and is the first brain structure affected by Alzheimer's dementia. It is also the only place in the human brain where new brain cells (neurons) are born throughout life, even as an adult.
The Highs and Lows of Animal Blood Pressures: Cuttlefish, Giraffe & Human
มุมมอง 481ปีที่แล้ว
The Highs and Lows of Animal Blood Pressures: Cuttlefish, Giraffe & Human
How Do Age and Exercise Affect My Metabolic Rate?
มุมมอง 720ปีที่แล้ว
How Do Age and Exercise Affect My Metabolic Rate?
What Happens to Fat When You Lose Weight?
มุมมอง 3.4Kปีที่แล้ว
What Happens to Fat When You Lose Weight?
Increase Your Stroke Volume to Improve Your Exercise Performance
มุมมอง 2.5K2 ปีที่แล้ว
Increase Your Stroke Volume to Improve Your Exercise Performance
Achieving Your Highest Lifetime Peak VO2max: What Will Your VO2max Curve Look Like?
มุมมอง 3442 ปีที่แล้ว
Achieving Your Highest Lifetime Peak VO2max: What Will Your VO2max Curve Look Like?
How Powerful is Your Engine? A Look at VO2max
มุมมอง 7422 ปีที่แล้ว
How Powerful is Your Engine? A Look at VO2max
The Genetically Programmed Diet of Homo sapiens
มุมมอง 5K2 ปีที่แล้ว
The Genetically Programmed Diet of Homo sapiens
How Well is Your Insulin Working?
มุมมอง 9412 ปีที่แล้ว
How Well is Your Insulin Working?
How Heart Failure Happens
มุมมอง 5732 ปีที่แล้ว
How Heart Failure Happens
The State of My Metabolic Machine: The 3 Most Important Numbers to Know
มุมมอง 6372 ปีที่แล้ว
The State of My Metabolic Machine: The 3 Most Important Numbers to Know
Seeing a Moonbow: Your Eyes vs. a Camera
มุมมอง 1672 ปีที่แล้ว
Seeing a Moonbow: Your Eyes vs. a Camera
The Hexagons of the Liver
มุมมอง 3612 ปีที่แล้ว
The Hexagons of the Liver
The Silent Epidemic of Fatty Liver Disease
มุมมอง 1.2K2 ปีที่แล้ว
The Silent Epidemic of Fatty Liver Disease
Optimizing Bike Fit to Prevent Injury
มุมมอง 5482 ปีที่แล้ว
Optimizing Bike Fit to Prevent Injury
Cycling to Maintain Muscle Mass: A Tour Around the Crank Cycle
มุมมอง 7K3 ปีที่แล้ว
Cycling to Maintain Muscle Mass: A Tour Around the Crank Cycle

ความคิดเห็น

  • @h1n1worm
    @h1n1worm หลายเดือนก่อน

    awesome. Thanks!

  • @yxtsama
    @yxtsama หลายเดือนก่อน

    What would be the practical implications of most neurons stemming from hippocampal neurogenesis are glutamatergic and not GABAergic? Apparently we also got some neurogenic activity in SVZ, do we know if we generate GABAergic ones there

  • @phabloabreu8502
    @phabloabreu8502 2 หลายเดือนก่อน

    Excellent

  • @maxentropy0305
    @maxentropy0305 2 หลายเดือนก่อน

    Excellent presentation. Thank you!

  • @zachcain2639
    @zachcain2639 2 หลายเดือนก่อน

    When a fat cell dies from inflammation, what happens to the triglycerides inside? Do they get shuttled out of the body or do they go into the bloodstream and get taken up by other fat cells?

  • @zachcain2639
    @zachcain2639 2 หลายเดือนก่อน

    Great discussion, thank you!

  • @maureenbennett809
    @maureenbennett809 2 หลายเดือนก่อน

    Good explanation. GREAT!😄

  • @zachcain2639
    @zachcain2639 2 หลายเดือนก่อน

    Does serum protein levels also affect glycation rates? Or is glucose pretty much always the limiting factor?

  • @zachcain2639
    @zachcain2639 2 หลายเดือนก่อน

    Why is the minimum temperature 284F outside the body but inside the body the reaction can happen at a much lower temp? Is it healthier to cook proteins in a pressure cooker which typically stays at 250F or lower?

  • @rajarshimahapatra6110
    @rajarshimahapatra6110 3 หลายเดือนก่อน

    Thank you for your extremely valuable content,it was very much helpful

  • @frostfox1208
    @frostfox1208 3 หลายเดือนก่อน

    Thank you. :-)

  • @infoplus9733
    @infoplus9733 3 หลายเดือนก่อน

    Great video. I am glad I never had one. A shame people make such poor decisions.

  • @hhhhhh9792
    @hhhhhh9792 3 หลายเดือนก่อน

    New neurons are also born in the olfa tory bulbs. This fact is the basis of the stem cell treatment that reversed Darek Fidyka's paralysis in 2014 whose spinal cord was completely severed years ago

  • @BetterHumanz
    @BetterHumanz 3 หลายเดือนก่อน

    I started my research on the 26 July with Retatrutide. I have lost 40lbs since then. The first 30 were quite fast. I made sure to eat 1g of protein per pound for my target body weight. Whats makes this such s gamechanger is regardless of every diet I tried including carnivore for 1yr I always fell off the wagon with that little voice telling me to eat icecream at night. I have never been able to shake that habit. But this GLP has literally taken all the voices in my head and locked them away in a silent room.. no more noise... and whats even more important is it gives you the motivation to change all the other areas in your life, like better diet, get better sleep, better exercise.. the results are lifechanging, so people can say what they like but if you can improve the quality of your life and stick around a lot longer on the planet because your body is running more efficiently then power to you

  • @JIm-w1b
    @JIm-w1b 3 หลายเดือนก่อน

    I have wondered too, about what happens to fat. My aunt Ruth was obese, she weighed almost 400 pounds. Then she got stomach cancer and was a month in the hospital, and in that month's time, she lost all of her weight, down to only like 96 pounds when she died. So there was 300 pounds of fat that exited her body. I would very much like to know, what happened to all of that fat? What became of it? Where did it go?

  • @AmyFerguson
    @AmyFerguson 4 หลายเดือนก่อน

    Baby neurons! I love this discription! I want to take care of them! :)

  • @singularity6761
    @singularity6761 4 หลายเดือนก่อน

    Everything what isn't in the body during birth shouldn't be put inside by humans afterwards.

  • @bmp713
    @bmp713 4 หลายเดือนก่อน

    I am trying to improve poor circulation, edema, and blood pooling with exercise training but there is not a lot of good resources for training the vascular system. You mentioned that exercise increases the diameter of blood vessels and I am interested to hear a lot more about how that works exactly. What kind of exercise and intensity do you think is most effective for dilating the blood vessels and veins? Do you know of any good resources with more information on training the vascular system?

  • @vince1229
    @vince1229 4 หลายเดือนก่อน

    There was a young woman who's tattoo ink caused an enlarged lymph node under her arm which they intitailly thought was a metastasis but it was nothing.

  • @muzduza44
    @muzduza44 4 หลายเดือนก่อน

    Question? I am 5'3" 197 lbs i just got an inversion table.i have alotta breast stomach fat.am i safe to put reverse decompression wieght pressure on the spine? I understand the decompression.but the stretch/pull from my wieght on the spine is my concern.

  • @bartercoins
    @bartercoins 4 หลายเดือนก่อน

    A very informative video. Thanks. It seems to me if one could eliminate a sufficient amount of his visceral fat and the chronic inflammation that accompanies it, many of his chronic health problems would go away.

    • @bartercoins
      @bartercoins 4 หลายเดือนก่อน

      You packed this video with so much information that I actually had to watch it twice and stop it to read the background graphics! Now, I have heard (through someone else's TH-cam video) that deep abdominal subcutaneous adipose tissue communicates with visceral fat and can become problematic (visceral-like), as a result. I presume, then, that if you sufficiently reduce your visceral fat, either the deep abdominal subcutaneous fat no longer becomes inflammatory or it just dissolves away, leaving only the beneficial superficial SC fat. Based on what I have observed with my own eyes, I believe there is now a sufficient amount of scientific biological information and technological progress to be able to quickly, easily, painlessly and non-invasively eliminate as much visceral, ectopic and subcutaneous fat as desired or as needed, with the ease of simply drinking a liquid or applying a serum to the skin. Surely this will revolutionize our treatment of disease. Truly we live in marvelous times!

  • @chrisd9759
    @chrisd9759 4 หลายเดือนก่อน

    Thank you for explaining what all - important myokines will do.

  • @pakistanibaloch2955
    @pakistanibaloch2955 5 หลายเดือนก่อน

    very useful video.... ❤❤

  • @alanmlkbanda
    @alanmlkbanda 5 หลายเดือนก่อน

    Insightful video but you don’t really explain why the the accumulation of glycated proteins happens in a healthy individual who is simply aging. You said the body usually repairs or disposes of those dysfunctional proteins but why doesn’t this process happen that well over time, through aging ?

  • @Rhuipana
    @Rhuipana 5 หลายเดือนก่อน

    Even when your 90 they keep producing

  • @atadali6199
    @atadali6199 5 หลายเดือนก่อน

    What about supplementing il-6 for muscles hypertrphy?

  • @lauraseaman39
    @lauraseaman39 5 หลายเดือนก่อน

    Thank you😘

  • @herni187
    @herni187 5 หลายเดือนก่อน

    Thank you for the information. Truly appreciate it.

  • @Papa_6
    @Papa_6 6 หลายเดือนก่อน

    Can strength training have similar effects? The “pump” creates shear force that forces adaptations doesn’t it?

    • @bmp713
      @bmp713 4 หลายเดือนก่อน

      Not nearly as much. Strength training causes large blood pressure spikes limiting blood being pumped back to the heart. It can have some effect but much less than aerobic exercises. Look up Joel Jamieson. He talks a lot about this and has lots of practical tips.

  • @randyhilton6629
    @randyhilton6629 6 หลายเดือนก่อน

    Thank you Doctor. Great visual aids! =D

  • @adrianbaker1408
    @adrianbaker1408 6 หลายเดือนก่อน

    Nice, thank you. Will watch it again>

  • @mottajunior4500
    @mottajunior4500 6 หลายเดือนก่อน

    What a amazing video, you explain so well. Congrats!

  • @masterkey4615
    @masterkey4615 6 หลายเดือนก่อน

    thank you for sharing

  • @soldiersvejk2053
    @soldiersvejk2053 7 หลายเดือนก่อน

    thanks!

  • @GAFB1122
    @GAFB1122 8 หลายเดือนก่อน

    Thank you! That was the best explanation I have watched on GLP-1.

  • @LuisCContreras
    @LuisCContreras 8 หลายเดือนก่อน

    Appreciate the detailed yet user-friendly explanations and illustrations!

  • @siiwok
    @siiwok 8 หลายเดือนก่อน

    what about for post gall bladder removal surgery diarreah? how to take?

  • @yelenashaykevich1628
    @yelenashaykevich1628 8 หลายเดือนก่อน

    Thank you so much!

  • @privatbruker5905
    @privatbruker5905 8 หลายเดือนก่อน

    1 thing tho the more stuff you add the harder it is when you come off.. Stay with semaglutide and try to use lowest effective dose possible and diet only for 6-8 months then start slowly eating more to increase metabolism then when recomped for few months then diet again that's how you get a nice body and health body If diet for too long its going to kill you're metabolism and you won't lose fat only muscle

  • @jaeshasway
    @jaeshasway 9 หลายเดือนก่อน

    Anything other than Mounjaro for GIP?

  • @studentaccount4354
    @studentaccount4354 9 หลายเดือนก่อน

    This is interesting. I like to take an integrative proactive approach. I guess it works for many people, weight can be a problem.

  • @studentaccount4354
    @studentaccount4354 9 หลายเดือนก่อน

    🎉😍TYVM

  • @1989deva
    @1989deva ปีที่แล้ว

    Hi! Thank you for translating science for regular people. I feel I learn a lot.

  • @mechcntr7185
    @mechcntr7185 ปีที่แล้ว

    Excellent video. Thank you!

  • @vincentrusso4332
    @vincentrusso4332 ปีที่แล้ว

    This is how educational videos should be made... take notes NASA... clear animation with easy to follow nomenclature.

  • @rajukumar-yu3oy
    @rajukumar-yu3oy ปีที่แล้ว

    Does a locked in syndrome patient grows new neurons ?

  • @alekseykasaev8706
    @alekseykasaev8706 ปีที่แล้ว

    I'm crying

  • @alekseykasaev8706
    @alekseykasaev8706 ปีที่แล้ว

    The best explanation

  • @jacquelinebess4379
    @jacquelinebess4379 ปีที่แล้ว

    So would that mean that, people who do deep breathing or mediation along with diet/exercise can lose more weight?

  • @bradstell2146
    @bradstell2146 ปีที่แล้ว

    Learning how to walk. Sorry. Typing with one hand.