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Thats true vagus nerve stimulation can decrease inflammation, but if we're talking about prolonged stress and DV shutdown then we eventually see metabolic changes (eg; fatigue) and decreased immune functioning and increased inflammation. There is also decreased oxytocin levels associated with social disconnection which negatively impacts cortisol regulation. The body's defence mechanisms have their limitations. Thankyou for the comment.

Thanks for the feedback but not quite sure what youre referring to Elizabeth?

sorry - yes what they did to the squid was cruel - we've done a lot of terrible things to animals in the name of science.

I think you will find that EMDR is described here as a bottom-up approach John but many quite smart people dont know about that hence the video!

​​@@markgrant100 I find it fascinating the video you used at the 45:05 mark. The creator of that video, Jay Shah of the NIH in Bethesda made that video Here is another video of that same circuit. Basics of musculoskeletal pain th-cam.com/video/9k-2xFuoNS8/w-d-xo.htmlsi=T7UdmwiTcNNPv-WH Myofascial pain syndrome is the MOST COMMON manifestation of chronic or persistent pain. ALL peoples with chronic pain present with myofascial trigger points. Dry needling is the most effective treatment for myofascial trigger points. Dry needling is not a stand alone cure but it will facilitate the recovery of the patient do address the underlying cause of their pain Here are a couple of excerpts from an Australian pain scientist and others. Moseley, himself wrote the excellent chapter on pain in the equally excellent 4th edition of the text Clinical Sport Medicine(2012). Here are some Moseley excerpts: “Trigger points are present in all patients with chronic pain and are thought to reflect sensitization of nociceptive processing in the central nervous system… Patients with active trigger points present with persistent regional pain… These patterns clearly reflect central convergence of peripheral inputs, which further implicates the central nervous system in their generation and contribution to a pain state.” Moseley GL. Pain: why and how does it hurt? Brukner & Kahn’s Clinical Sports Medicine. North Ryde, NSW: McGraw-Hill Australia Pty Ltd; 2012 "elimination of myofascial trigger points is an important component of the management of chronic musculoskeletal pain” and “we have found ischemic compression and dry needling to be the most effective" pubmed.ncbi.nlm.nih.gov/7850884/ Myofascial pain J R Fricton. Baillieres Clin Rheumatol. 1994 Nov. MFP is a regional muscle pain disorder characterized by localized muscle tenderness and pain and is the most common cause of persistent regional pain. The affected muscles may also display an increased fatiguability, stiffness, subjective weakness, pain on movement and slightly restricted range of motion that is unrelated to joint restriction. MFP is frequently overlooked as a diagnosis because it is often accompanied by signs and symptoms in addition to pain, coincidental pathological conditions, and behavioural and psychosocial problems The difficulty in managing MFP lies in the critical need to match the level of complexity of the management programme with the complexity of the patient's situation. Failure to address the entire problem, through a team approach if needed, may lead to failure to resolve the pain and perpetuation of a chronic pain syndrome. pubmed.ncbi.nlm.nih.gov/16259310/ A review of myofascial pain and fibromyalgia--factors that promote their persistence Robert D Gerwin. Acupunct Med. 2005 Sep Chronic muscle pain (myalgia) is a common problem throughout the world. Seemingly simple, it is actually a difficult problem for the clinician interested in determining the aetiology of the pain, as well as in managing the pain. The two common muscle pain conditions are fibromyalgia and myofascial pain syndrome. The problem these syndromes pose lies not in making the diagnosis of muscle pain. Rather, it is the need to identify the underlying cause(s) of persistent or chronic muscle pain in order to develop a specific treatment plan. Chronic in myalgia may not improve until the underlying precipitating or perpetuating factor(s) are themselves managed. Precipitating or perpetuating causes of chronic myalgia include structural or mechanical causes like scoliosis, localised joint hypomobility, or generalised or local joint laxity; and metabolic factors like depleted tissue iron stores, hypothyroidism or Vitamin D deficiency. Sometimes, correction of an underlying cause of myalgia is all that is needed to resolve the condition. www.sciencedirect.com/topics/nursing-and-health-professions/myofascial-painMyofascial Pain Syndrome Andrea L. Nicol MD, MSc, ... F. Michael Ferrante MD, in Essentials of Pain Medicine (Fourth Edition), 2018 Myofascia l pain or regional musculoskeletal pain is one of the most common pain syndromes encountered in clinical practice. Myofascial pain represents the most common cause of chronic pain, including neck and shoulder pain, tension headaches, and lower back pain

Not that I am aware of - other than if you had a severe dissociative condition, such as DID (Dissociative Identity Disorder). Individual circumstances and emotional style dictate who will benefit from EMDR or any other modality which often only becomes apparent after you have given it a try.

The squid wth chronic pain was the one best at surviving threats

... and the ones who didn't have the anesthetics, developed chronic pain. They became hyper aware of their surroundings, thus more cautious! But being hyper cautious for humans can lead to increased fear and anxiety, even when there is no threat. So, though our brains are doing what they need to do to avoid another injury or trauma, it can become a viscous cycle, causing more anxiety, fear, chemical imbalance and pain. Just what I have learned. I am not a doctor. 💕⚘💕

Nirmal Gerow I guess he’s not able to help.