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Coag Coach
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เข้าร่วมเมื่อ 31 ม.ค. 2015
Insights from a blood diseases doctor (hematologist) on hematology topics covered on the Internal Medicine board exams.
How To Interpret the Lupus Anticoagulant Panel
Interpreting the lupus anticoagulant panel can be hard. It becomes easier when you recognize that it is one big mixing study. Hematologist, Dr. Toyosi Onwuemene, helps us with the interpretation.
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How To Interpret Mixing Studies
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Mixing studies help us distinguish coagulation factor deficiencies from inhibitors. But how do we interpret the results? Hematologist, Dr. Toyosi Onwuemene, walks us through the interpretation.
How to Evaluate a Prolonged PT
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So the activated partial thromboplastin time (aPTT) is normal; but the prothrombin time (PT) is prolonged. How do you work it up? Hematologist, Dr. Toyosi Onwuemene, reviews the evaluation.
How To Evaluate a Prolonged PT and aPTT
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What do you do when both the prothrombin time (PT) and activated partial thromboplastin time (aPTT) are prolonged? For starters, you think about what information the prolonged aPTT and the PTT give you about the coagulation cascade (Are you feeling anxious yet?). Hematologist, Dr. Toyosi Onwuemene, walks you through the evaluation.
How to Evaluate a Prolonged aPTT
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When the activated partial thromboplastin time (aPTT) is prolonged; but the prothrombin time is normal, that narrows down the possibilities to a deficiency or inhibitor of the intrinsic pathway. In this video, hematologist, Dr. Onwuemene walks us through the evaluation.
Get These 3 Tests Every Time You Evaluate Anemia
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Anemia is so common that we don’t respect it. We guess at the reason for anemia and hope for the best. In this video, hematologist, Dr. Toyosi Onwuemene, discusses three essential tests for anemia that you should order every time.
Microcytosis - Iron Deficiency or Hemoglobinopathy?
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The presence of microcytosis may indicate iron deficiency vs. hemoglobinopathy. But before all the tests are back, can you distinguish between the two? Hematologist, Dr. Toyosi Onwuemene, shows us a way to make a quick educated guess.
CBC Alphabet Soup - MCV, MCH, MCHC, RDW, and NRBC
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When you review the complete blood count (CBC), what is the significance of the MCV, MCH, MCHC, RDW, and NRBC? How can you differentiate between them? Hematologist, Dr. Toyosi Onwuemene, introduces us to the CBC’s less popular members.
Why does this patient have Monocytosis?
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When the Consult Service is called about a patient with B-symptoms and monocytosis, it is easy to jump immediately to the bone marrow biopsy. Before the bone marrow biopsy, hematologist, Dr. Toyosi Onwuemene, discusses why a broad differential should be considered.
Should We Write the Prescription without Seeing the Patient?
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The Heme Consult service was asked to write an order for eculizumab in a patient with a history of atypical hemolytic uremic syndrome. Why not just write the prescription and call it a day? Hematologist, Dr. Onwuemene, discusses the reasons for which a formal consultation evaluation is warranted.
Should We Restart Anticoagulation?
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The Heme Consult service was asked to address the case of a patient who missed taking anticoagulation for 4 months. In this video, hematologist, Dr. Onwuemene reviews the factors that led to their final recommendations.
Does this Patient with Methotrexate Toxicity need a Bone Marrow Biopsy?
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A patient is admitted with pancytopenia in the setting of outpatient use of methotrexate. The hematology service is consulted for a bone marrow biopsy. In this video, hematologist, Dr. Toyosi Onwuemene, discusses her process for evaluating the bone marrow biopsy request in light of the clinical findings.
Did Factor V Leiden Cause this Patient's Acute Stroke?
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A young woman presenting with acute stroke is found to be heterozygous for factor Leiden deficiency. Does factor V Leiden deficiency explain the acute stroke. In this video, hematologist, Dr. Toyosi Onwuemene, discusses the implications of factor V Leiden heterozygosity and whether it accounts for the patient’s clinical presentation.
How I Think About Anti-heparin/PF4 Testing in HIT
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When we are looking for heparin-induced thrombocytopenia, we typically start with anti-heparin/PF4 testing. Testing is great; but what do you do with the results? In this video, hematologist, Dr. Onwuemene explains the importance of calculating the pre-test probability and how to match pre-test probability with the anti-heparin/PF4 result.
How to think about the type, screen, and crossmatch
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In the inpatient setting, physicians often request a type, screen, and crossmatch. However, these terms are not always well-understood. In this video, Dr. Onwuemene explains what it means to determine the major blood group antigens, evaluate for reactivity to minor blood group antigens, and ensure that potential transfused unit is compatible with the patient.
Does this patient have immune thrombocytopenia (ITP)?
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Does this patient have immune thrombocytopenia (ITP)?
Does this Patient Have Thrombotic Thrombocytopenic Purpura (TTP)?
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Does this Patient Have Thrombotic Thrombocytopenic Purpura (TTP)?
Did this Patient Experience Anticoagulant Failure?
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Did this Patient Experience Anticoagulant Failure?
When Should I Order Thrombophilia Testing?
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When Should I Order Thrombophilia Testing?
Which Hemostasis Test Should I Order?
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Which Hemostasis Test Should I Order?
How I Think About the Coagulation Cascade
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How I Think About the Coagulation Cascade
When Are Blood Product Modifications Needed?
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When Are Blood Product Modifications Needed?
Does the Patient Need a Bone Marrow Biopsy?
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Does the Patient Need a Bone Marrow Biopsy?
Heme Consults # 30 - The Best Experience
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Heme Consults # 30 - The Best Experience
Heme Consults # 29 - When you are in clinic
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Heme Consults # 29 - When you are in clinic
Heme Consults # 28 - The middle of the night: What to expect
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Heme Consults # 28 - The middle of the night: What to expect
Heme Consults # 26 - Common Consult Questions
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Heme Consults # 26 - Common Consult Questions
Great video Dr Onwuemene! I am I hematology fellow and this is always confusing. Would love to see some example cases if you have some.
👍🏻👍🏻👍🏻
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No one single video on TH-cam tells/explain the Difference a Negative or a Postive outcome AFTER taking this test. How hard is that?
Wow this was an amazing explanation. Thank you)🙏
I am 25 years old and have monocytosis (14%) and low HDL. I have no other symptoms, any idea on what’s going on? I am a medicine student
Delayed transfusion related complications is-circulatory overload/iron overload/ septicemia/hypocalcemia Which is the right answer plz help
the best lecturer. from kurdstan/iraq
this video hit the target. many many thanx
Hi is I just found out I have this desees is it contagious ??
This is an amazing way of explaining the coagulation cascade. Thank you very much.
Excellent! Thank you.
I’m late in viewing this video, and I don’t know a lot about platelets or coagulation. I was a nurse, so I’m familiar with medical terminology to some extent, but my questions are very basic. If PF4 is released by activated platelets, what causes platelets to become activated?
Best
Nice content 🎉
Wow a very brief but very comprehensive video Thanks a lot 🎉
omg thank you so much. I have no idea why I never understood this throughout med school, but now that I'm finally almost done (if I pass step 2 lol), it makes sense the way you explained it
What about not having a normal mcv recorded by blood tests but having normal iron studies?
I am currently going through this as a patient. Weight loss 2 years ago, but has since stopped. I actually gained some weight. A period of night sweats, bone pains that has stopped. Gastro issues that are ongoing. Vision issues, hydronephrosis in 1 kidney supposedly due to kidney stones. Monocyte count was 1300, but the percentage is 7.4%. Neutrophils were 14,500 and at 81%. Lymphocytes are 1600, but at 9.4% very low. I do have hypothyroidism as well. CMML thoughts has me nervous. I'm hoping it's lupus.
You made it so easy to comprehend a complex concept!
Well presented
Thank you this vid helped me a lot.
Thanks alot what a beutiful sound stuck in mind
Thank you for this! I understand this so much better now :D
really helpful!!!!
So simple to understand. Thank you ma'am
Thank you
thank you this was veryyyyyyy helpful
Thank you so much 💓
Thanks !
Thank you so much you made it so simple, keep up the good work 😊
This is weird thats not even a real person. THATS AI. CRAZY!!!
Thank you! This was so helpful!
Thank u for that Great vid. Best wishes from Egypt
Crystal clear... Amazing 👍
What about a high RDW, normal Ferritin, and Transference, normal MCV
Thanks
Nice. Thanks ❤😊
Thank you so much for your explanations! you're clear, concise and passionate about hematology! As a student, your videos are godsend! keep them coming!!
Excellent demonstration with clear and lucid language Thank you
Amazing video. Thank you so much!
And how do you treat yhe underlying disorder?
Hey, doc. I’ve had elevated monocytes(everything else in range) for the past three months. I went to a haematologist and she told me not to be concerned unless symptoms appear. Do you think I should push for a bone marrow biopsy to make sure the cause is not malignant. I’m 24 years old by the way.
Hi are you good?
🎉this is so helpful thank you❤
Very helpful presentations. Please do more videos on haematology topics especially haemotologic malignancies.
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Thank you for providing this succinct explanation for such a complicated topic. One question I have - are all three components required for a LA diagnosis? What would be the interpretation for results that show a 1) prolonged LA test 2) PL dependence, but 3) CORRECTION with mix?
Great insight
Great video! Was treat for a PE with Heparin and around day 2 I developed rash/hives on my back, under arm pits, and where the blood pressure cuff was. Locations that may have been sweating. Hospital treated it like a allergy to the bedding but 4 days later I still have this. My platelet counts were stable while in the hospital but I usually run around 150. Not sure if this is part of a reaction and related to HIT or not. On eliquis currently.