Welcome to Immunize.org’s Ask the Experts resources. This Ask the Experts question is presented by Immunize.org’s Kelly L. Moore, MD, MPH.
Question:
Do infants born soon after maternal RSV vaccination need RSV preventative antibody?
Answer:
Yes. Infants born less than 14 days after the mother received RSV vaccine should receive nirsevimab (Beyfortus, Sanofi). Infants born within 14 days after maternal vaccination may not have had sufficient time in utero to receive adequate protection from maternal RSV antibodies produced after vaccination. Infants born 14 days or more after maternal vaccination are not recommended to receive nirsevimab except in rare circumstances where maternal antibodies may be insufficiently effective. See a separate question for details on those circumstances: www.immunize.org/ask-experts/when-might-an-infant-entering-the-first-rsv-season-need-nirsevimab-even-though-the-mother-was-properly-vaccinated-more-than-14-days-before-delivery
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