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VJNeurology
United Kingdom
เข้าร่วมเมื่อ 13 พ.ค. 2020
The Video Journal of Neurology (VJNeurology) is an independent, global, open-access video journal, dedicated to providing trusted and up-to-date information in order to improve the awareness and understanding of neurology.
Our goal is to expedite learning through the sharing of new data and expert opinion, and to rapidly disseminate the latest news and information to healthcare professionals, worldwide, on a range of innovative digital media - including video and blog formats.
VJNeurology content will be led by an editorial board of highly respected thought leaders with a combined expertise that spans the spectrum of neurological disorders. All content will be created and published under the guidance of this board of world-leading experts.
Our goal is to expedite learning through the sharing of new data and expert opinion, and to rapidly disseminate the latest news and information to healthcare professionals, worldwide, on a range of innovative digital media - including video and blog formats.
VJNeurology content will be led by an editorial board of highly respected thought leaders with a combined expertise that spans the spectrum of neurological disorders. All content will be created and published under the guidance of this board of world-leading experts.
Understanding smoldering pathology in MS
Alicja Kalinowska, MD, PhD, Poznan University of Medical Sciences, Poznań, Poland, explains the difference between smoldering multiple sclerosis (MS) and progressive MS. A smoldering lesion involves ongoing immune activity in the macrophages surrounding the center of the plaque. However, smoldering MS is a term that goes beyond smoldering lesions, describing a diffuse smoldering pathological process thought to drive progressive accumulation of disability in MS in the absence of clinical relapses. Other processes are involved in smoldering MS, including cortical lesions, spinal cord degeneration, and B-cell meningeal infiltration, highlighting the complexity of MS. These processes may be correlated to progression independent of relapse activity (PIRA). Prof. Kalinowska highlights how PIRA is challenging to target using the current MS therapies and notes the promise of BTK inhibitors to act on both innate and adaptive immune cells that are linked to the pathology of MS. BTK inhibitors are currently being trialed for the treatment of MS. Prof. Kalinowska concludes that there is a need to establish new terms and definitions in this therapeutic area. This interview took place at the European Academy of Neurology (EAN) Annual Meeting 2024 in Helsinki, Finland.
These works are owned by Magdalen Medical Publishing (MMP) and are protected by copyright laws and treaties around the world. All rights are reserved.
These works are owned by Magdalen Medical Publishing (MMP) and are protected by copyright laws and treaties around the world. All rights are reserved.
มุมมอง: 75
วีดีโอ
Etiology-specific treatment approach in neonatal status epilepticus
มุมมอง 589 ชั่วโมงที่ผ่านมา
Maria Roberta Cilio, MD, PhD, Université Catholique de Louvain, Brussels, Belgium, discusses a novel approach to the detection and diagnosis of seizures and status epilepticus (SE) in neonates. She emphasizes the need to stratify patients’ treatment according to seizure semiology and etiology, and how this can inform precision medicine approaches. Precision medicine is already routinely used to...
Opioid use in patients with medication overuse headache
มุมมอง 79 ชั่วโมงที่ผ่านมา
Gisela Terwindt, MD, PhD, Leiden University, Leiden, Netherlands, highlights the need to avoid opioids as treatments for headache, referring to the opioid crisis in the USA as an example of the negative effects of opioid prescription. 13% of migraine patients in the Netherlands have used opioids, with some having used them preventatively, and 2% of those who have used opioids had not been presc...
Psychological support needs for people with phenylketonuria
มุมมอง 79 ชั่วโมงที่ผ่านมา
Bernadette Sheehan Gilroy, Munster Technological University, Kerry, Ireland, shares her thoughts on the key unmet need for psychological support in phenylketonuria (PKU) management. The oldest patients with PKU who have been on long term dietary support following the introduction of newborn screening in Ireland are approaching 58 years old. There is a lack of resources for adults with PKU, part...
Skin innervation as a prognostic biomarker in ALS
มุมมอง 399 ชั่วโมงที่ผ่านมา
Raffaele Dubbioso, MD, PhD, University of Naples Federico II, Naples, Italy, discusses his work assessing peripheral sensory abnormalities in amyotrophic lateral sclerosis (ALS) and how these correlate with the severity and prognosis of the disease. ALS has long been described as motor neuron disease, but more recently, numerous non-motor symptoms have been recognized. These include cognitive a...
Characterizing double-negative NMOSD
มุมมอง 99 ชั่วโมงที่ผ่านมา
Antonio Malvaso, MD, IRCCS “C. Mondino” National Neurological Institute, University of Pavia, Pavia, Italy, discusses the findings of his systematic review and meta-analysis, which aimed to characterize double-negative neuromyelitis optica spectrum disorder (NMOSD). Dr Malvaso stresses that the clinical profile of double-negative NMOSD is poorly defined in the literature. The systematic review ...
Impact of parental smoking on MS risk
มุมมอง 99 ชั่วโมงที่ผ่านมา
Caterina Ferri, MD, PhD, St Anna University Hospital, University of Ferrara, Ferrara, Italy, discusses her research evaluating the association between parental smoking and risk for multiple sclerosis (MS). Active smoking is a known risk factor and prognostic factor for MS, and passive smoke exposure has been suggested as a risk factor. Parental smoking is little studied. This large, multination...
Diagnosing narcolepsy: the revised classification of CNS hypersomnolence disorders
มุมมอง 5416 ชั่วโมงที่ผ่านมา
Lucie Barateau, MD, PhD, Gui-de-Chauliac Hospital, CHU Montpellier, Montpellier, France, discusses narcolepsy and its diagnosis. Narcolepsy types 1 and 2 (NT1 and NT2) are rare disorders that affect children and young adults, characterized by excessive daytime sleepiness. The presence of cataplexy distinguishes NT1 from NT2. Pathophysiologically, orexin deficiency underlies NT1, but NT2 is less...
Repurposing MS and NMOSD treatments for CIDP
มุมมอง 3216 ชั่วโมงที่ผ่านมา
Alicja Kalinowska, MD, PhD, Poznan University of Medical Sciences, Poznań, Poland, discusses medications used for multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) that have potential to be repurposed for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). Anti-CD20 antibodies are one such group with strong rationale for repurposing, given the importance o...
The gut microbiome in restless leg syndrome: searching for novel biomarkers
มุมมอง 6516 ชั่วโมงที่ผ่านมา
Angelica Montini, MD, PhD Candidate, University of Bologna, Bologna, Italy, provides insights into her work looking at the gut microbiota in restless leg syndrome (RLS). There is strong evidence that RLS has a bidirectional relationship with inflammation. Notably, an association between inflammatory bowel disease and RLS had been evidenced. Dr Montini used a metagenomic approach to test the hyp...
Education in autonomic medicine in Europe
มุมมอง 1616 ชั่วโมงที่ผ่านมา
Autonomic medicine plays a widespread role across the neurology field, from movement disorders, to epilepsy, to neuromuscular disorders, and more. It’s therefore important for every practitioner of neurology to have knowledge of autonomic medicine. Diogo Reis Carneiro, MD, Hospitais da Universidade de Coimbra, Coimbra, Portugal, discusses his survey on education in autonomic medicine in Europe,...
The current treatment landscape for myasthenia gravis
มุมมอง 3216 ชั่วโมงที่ผ่านมา
Francesco Sacca, MD, PhD, University of Naples Federico II, Naples, Italy, discusses the treatment landscape for myasthenia gravis (MG). Until recently, the only treatments for MG were corticosteroids or non-steroidal immunosuppressants, and pyridostigmine as symptomatic treatment. Patients non-responsive to the standard treatments would be treated with intravenous immunoglobulin (IVIg) or plas...
Autonomic markers for the differential diagnosis of pure autonomic failure
มุมมอง 2216 ชั่วโมงที่ผ่านมา
Junie Shiwen Koay, MBBS, University College London Queen Square Institute of Neurology, London, UK, discusses her research into the use of multimodal autonomic biomarkers for the differential diagnosis of pure autonomic failure. In the early stages, α-synucleinopathies can be difficult to differentiate, especially in patients with abnormal presentations. Pure autonomic failure is characterized ...
Palliative care in severe epileptic conditions
มุมมอง 5816 ชั่วโมงที่ผ่านมา
Reetta Kälviäinen, MD, PhD, University of Eastern Finland, Kuopio University Hospital, Kuopio, Finland, discusses the topic of palliative care in severe epileptic conditions. She emphasizes the clear need for additional education and discussion about palliative care for epilepsy. The approach to epilepsy management over time should not be dichotomous, instead symptomatic treatment needs to be i...
How to approach the classification of neuromuscular disorders
มุมมอง 2716 ชั่วโมงที่ผ่านมา
Nicolas Dubuisson, MD, Cliniques universitaires Saint-Luc, Brussels, Belgium, outlines his talk on the classification of neuromuscular disorders. Classification is important to improving diagnostic yield as neuromuscular disorders have a wide range of etiologies. Dr Dubuisson utilizes a stepwise approach to narrow in on the diagnosis in a logical manner. Age of onset is an important initial cla...
Current diagnostic criteria exclude many pediatric patients with probable migraine
มุมมอง 2214 วันที่ผ่านมา
Current diagnostic criteria exclude many pediatric patients with probable migraine
Formation of the AHS autonomic disorders special interest section
มุมมอง 1314 วันที่ผ่านมา
Formation of the AHS autonomic disorders special interest section
Preventive treatment approach in pediatric migraine
มุมมอง 7814 วันที่ผ่านมา
Preventive treatment approach in pediatric migraine
POTS, hEDS, and migraine: shedding light on the connections
มุมมอง 2414 วันที่ผ่านมา
POTS, hEDS, and migraine: shedding light on the connections
Research goals from the American Headache Society
มุมมอง 2014 วันที่ผ่านมา
Research goals from the American Headache Society
Diagnosing autonomic function disorders in patients with headache
มุมมอง 6214 วันที่ผ่านมา
Diagnosing autonomic function disorders in patients with headache
Investigating disparities in the care of pediatric headache
มุมมอง 4514 วันที่ผ่านมา
Investigating disparities in the care of pediatric headache
High placebo response in pediatric headache clinical trials
มุมมอง 614 วันที่ผ่านมา
High placebo response in pediatric headache clinical trials
Potential of delta opioid receptors as a target for migraine
มุมมอง 914 วันที่ผ่านมา
Potential of delta opioid receptors as a target for migraine
Dysautonomia in patients with migraine
มุมมอง 1814 วันที่ผ่านมา
Dysautonomia in patients with migraine
Developing delta opioid receptor agonists for migraine treatment
มุมมอง 1414 วันที่ผ่านมา
Developing delta opioid receptor agonists for migraine treatment
The impact of estrogen exposure on vascular risk in women with migraine
มุมมอง 4514 วันที่ผ่านมา
The impact of estrogen exposure on vascular risk in women with migraine
Lidocaine occipital nerve blocks found to be effective in treating status migrainosus in children
มุมมอง 5814 วันที่ผ่านมา
Lidocaine occipital nerve blocks found to be effective in treating status migrainosus in children
The challenges and opportunities of using AI in medicine
มุมมอง 2614 วันที่ผ่านมา
The challenges and opportunities of using AI in medicine
Thank you. You and prof G are incredible despite you dont have the same opinion on some matters. Thank you for this video and precious thoughts ❤ We really appreciate what you are doing for MS community.
Wow! Thank you so much for this video. This has been a long-time coming for my little research group in Canada. Much appreciated.
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