Respiratory | External Respiration: Ventilation Perfusion Coupling

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  • เผยแพร่เมื่อ 26 ก.ย. 2024
  • Correction @27:50 , the ventilation INCREASES as we go down from the Apex to the Base, but the perfusion increases SIGNIFICANTLY more. Since Perfusion increases more than Ventilation as we move to the base of the lung, the V/Q ration decreases at the base
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    In this lecture Professor Zach Murphy will be teaching you about external respiration, simply known as breathing. During this lecture we will be discussing ventilation perfusion coupling. We hope you enjoy this lecture and be sure to support us below!
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ความคิดเห็น • 306

  • @zdangor7289
    @zdangor7289 5 ปีที่แล้ว +280

    I've never seen someone teach with such passion and sincerity.. Thank you so much

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    @ashtonm.3825 3 ปีที่แล้ว +48

    This guy is the only reason I'm getting through med school....lol. I just want to know who the 21 people are that didn't like the video!!!!!!!!! (probably faculty members seeing their jobs going away)

    • @JSG818
      @JSG818 7 หลายเดือนก่อน +1

      i was thinking the same thing!

    • @ebbawaqgizachew7687
      @ebbawaqgizachew7687 7 หลายเดือนก่อน

      😂😂😂👍👍👍👍

    • @brainboosteredu.3928
      @brainboosteredu.3928 4 หลายเดือนก่อน

      Real

  • @gia3586
    @gia3586 4 ปีที่แล้ว +107

    Zach,
    I'm a Term 1 medical student and I just want to stop by and tell you how much I appreciate all your videos. I'm on my last week of the first term and we have our CPR2 exam coming up and your videos have clarified so many points in their lectures. A year ago my father died from a massive pulmonary embolism. As you can imagine, its very difficult for me to listen to these concepts and understand just how much he went through during his final moments. He's my sole motivation for becoming a doctor. I hope I can make him proud in the years to come but as of right now I've been able to accomplish that thanks to you and your channel! I look forwards to watching many more of your videos throughout my medical school journey. Thanks again!!!

  • @jonathanparrott8942
    @jonathanparrott8942 4 ปีที่แล้ว +42

    You guys are saving me a lot of heart ache with my pulmonary physiology lectures. Humble thanks! Your efforts are greatly appreciated!

  • @emilyroloff2619
    @emilyroloff2619 4 ปีที่แล้ว +25

    Thank you so much. I'm in dedicated right now studying for Step 1, and this is the first time I've ever understood ventilation and perfusion. Ever. I cannot thank you enough.

  • @yellowpurples832
    @yellowpurples832 3 ปีที่แล้ว +4

    OMG!! This is absolutely fantastic!! If you understand the basic concept - like what you are explaining, you can never get lost anywhere in Respiratory Pathophysiology!! Thank You Very much!

  • @Superhuman831
    @Superhuman831 7 ปีที่แล้ว +43

    best teacher ever! seriously thank you for helping me get through my physio in the course of 6 weeks -_-...yes 6 weeks. I learn more from you then my professor so I stay home and study my chapters with ninja nerd. Thank you

    • @NinjaNerdOfficial
      @NinjaNerdOfficial  7 ปีที่แล้ว +13

      +Breeann Barcelona wow! Thank you for the kind words they mean so much. You are a brave individual for taking a physiology course in six weeks. I hope these videos really helped and I wish you the best of luck in your future endeavors.

    • @riteshdeshmukh8672
      @riteshdeshmukh8672 5 ปีที่แล้ว +2

      Ninja Nerd Science sir iam really thakfull for your teaching....earlier hardly i studied that toowith fear...afteri started watching ur videos,iam studying out ofjoy now sir

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    I actually understand what you were teaching. Thank you so much for helping a difficult class in nursing school make sense

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    @TLKK2020 5 ปีที่แล้ว +10

    Holy moly he’s freakin’ good! Better at teaching than my instructors! He makes it so simple and straight to the point!

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    WHAT ELSE TO SAY THEN: I LOVE STUDYING WITH NINJA NERD!! THANK YOU FOR HELPING ME BECOME A DENTIST :-)

  • @brianaschaffner8272
    @brianaschaffner8272 3 ปีที่แล้ว +1

    First year veterinary student here and your channel has been a lifesaver for all my physiology courses, so I wanted to comment a big THANK YOU!!

  • @andrewopp.4554
    @andrewopp.4554 ปีที่แล้ว

    This man is a genius he teaches and explains things that you didn't understand in your past physiology lecture in class. God richly bless🙏 your for passion and sincerity to let every student comprehend.

  • @menasalman8534
    @menasalman8534 4 ปีที่แล้ว +9

    YOU COME THROUGH EVERY SINGLE TIME OMG I APPRECIATE YOU SO MUCH

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    Words are useless to appreciate.Finding this channel was the best event in my entire life

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    @randihowey3680 5 ปีที่แล้ว +6

    Your video was awesome!! I never comment on these things, but you deserved a response. Keep it up, Ninja Nerd!!! On my way to watch more.

  • @annaflores4322
    @annaflores4322 3 ปีที่แล้ว +5

    Always such great explanations! I am rewatching the pulmonary lectures and they make so much more sense.

  • @mwizakondowe3366
    @mwizakondowe3366 3 ปีที่แล้ว +7

    Respiratory Physiology has always been a nightmare for me to study until I came across your lectures. Thank you so much for taking the time to explain intricate information to such simplicity. Keep up the awesome work.👏👏👏

  • @BlaackAnchor
    @BlaackAnchor 5 ปีที่แล้ว +75

    At time 27:30, you said that ventilation decreases from apex to base, but actually it increases from apex to base of the lung. Perfusion also increases from apex to base, but much more significantly that we have a lower V/Q at the base.

    • @caidenlu
      @caidenlu 5 ปีที่แล้ว +2

      but shouldnt air goes against the direction of the gravity?

    • @BlaackAnchor
      @BlaackAnchor 5 ปีที่แล้ว +2

      @@caidenlu we are talking about ventilation here, not just air. Thanks for your input....

    • @caidenlu
      @caidenlu 5 ปีที่แล้ว +2

      @@BlaackAnchorbut isn't ventilation the movement of air? but i get youre right, just still got confused here about why

    • @caidenlu
      @caidenlu 5 ปีที่แล้ว +2

      @@BlaackAnchor is it because at the end of expiration, the FRC at the apex area is more than the bottom, so the ventilation at the apex is considered lower?

    • @omarnakhleh6600
      @omarnakhleh6600 5 ปีที่แล้ว

      @@caidenlu The ventilation is low because the cross sectional area (surface area) is low in the apex of the lungs

  • @leahgunderman3733
    @leahgunderman3733 ปีที่แล้ว

    Helping me get through CRNA school!!! This page is such a blessing

  • @sairagul5058
    @sairagul5058 4 ปีที่แล้ว +1

    Just Awesone .... I go into ecstasies whenever I watch your videos . It helps me alot in my medical studies . Thank you soooooo much💞💞💞💞💞❣😊

  • @samoei3780
    @samoei3780 5 ปีที่แล้ว +7

    Wow! this is exremely wonderful. Thanks alot, you made this things very easy.
    Point of correction- The lower zones of the lung ventilate better than the upper zones and the middle zones have
    intermediate ventilation.

    • @samoei3780
      @samoei3780 5 ปีที่แล้ว

      In addition ventilation perfusion ratio increases three times in the apex than in the base

    • @SunShine-vq9sz
      @SunShine-vq9sz 3 ปีที่แล้ว

      But in that won't the v/q ratio be disturbed?Could u explain why u think ur point is right?

  • @afaf6765
    @afaf6765 4 ปีที่แล้ว +8

    Tomorrow I have an exam on all respiratory subjects and you are saving my life❤❤❤😢thank you sir.
    Edit: my exam was so hard 💔

  • @danielmaroa3344
    @danielmaroa3344 4 ปีที่แล้ว +2

    Thanks you so much for the presentation on V/Q ratio .
    It was amazing .
    Great.

  • @langhejoel9272
    @langhejoel9272 3 ปีที่แล้ว +1

    U guys did it again men making my exams brighter i appreciate mates

  • @MaryDiaz-tc9ql
    @MaryDiaz-tc9ql 2 ปีที่แล้ว

    Zach, i'm in respiratory school and I got to tell you man you've saved my butt so many times with your videos. Thank you for your hard work!

    • @cassandracastillo2736
      @cassandracastillo2736 7 หลายเดือนก่อน

      I will be a RT student this summer any advice?

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    @brainboosteredu.3928 4 หลายเดือนก่อน

    Thank you so much for this video, you're literally saving lives.

  • @quaintonquaint5486
    @quaintonquaint5486 10 หลายเดือนก่อน

    Perfect videos for Respiratory Therapy school, thank you so much!

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    @chilalaphinious8602 3 ปีที่แล้ว

    these videos have really helped in a wide range.

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    @5amendoza 5 ปีที่แล้ว +5

    You are a wonderful teacher! Thank You for helping me through pathophysiology

  • @JayyThao
    @JayyThao 11 หลายเดือนก่อน

    I’m a student nurse anesthetist. I wish my physiology course would just post your videos instead of their lectures. You’re awesome.

  • @danielhernandez8668
    @danielhernandez8668 4 ปีที่แล้ว

    Im beginning to think the people who dislike this video are the professors who "teach" the subject but suck at explaining it. What a bunch of haters. You rock dude keep it up!

  • @kaspack10
    @kaspack10 4 ปีที่แล้ว +6

    best videos ever - actually makes learning this stuff, dare I say, FUN?!

  • @jessicalynn4062
    @jessicalynn4062 5 ปีที่แล้ว +1

    you give the human body it's proper dues! love your videos. big thank you!

  • @elizabethjoecha
    @elizabethjoecha 3 ปีที่แล้ว +1

    Thank you so much for the video on V/Q. This is awesome.

  • @marypaye1730
    @marypaye1730 4 ปีที่แล้ว +1

    You broke that down to the ground! Amazing Job!

  • @katherinevargas3525
    @katherinevargas3525 4 ปีที่แล้ว +1

    This was so perfect and helpful in every way! one of my favorite videos on TH-cam.

  • @athraaimad6859
    @athraaimad6859 4 ปีที่แล้ว +4

    Hello u said that ventilation is better in the top(apex ) of the lung ,but actually it should be decreased bec all books said that lower zones of the lung ventilated better thant upper ,i wish u explain!! + ur the best in explaining physiology

  • @deenahbyramjee2817
    @deenahbyramjee2817 4 ปีที่แล้ว +1

    your videos are so amazing. THANK YOU! THANK YOU! THANK YOU!

  • @nyananguei1928
    @nyananguei1928 3 ปีที่แล้ว +1

    Extremely perfect!
    I really enjoyed it bro. Congratulations

  • @aaryaalone2667
    @aaryaalone2667 ปีที่แล้ว +3

    Thankyou for everything 🙏🙏

  • @luizcosta9359
    @luizcosta9359 5 ปีที่แล้ว +2

    I am brazilian and this video helped me so much

  • @priyad5899
    @priyad5899 3 ปีที่แล้ว

    He literally made it simple. Thankyou!

  • @THE______TRUTH
    @THE______TRUTH 4 ปีที่แล้ว +42

    I feel like you should have emphasized that the smooth muscle in the arterioles contracts and relaxes because capillaries dont have smooth muscle and so the illustration can be misleading.

  • @brunaiglesias5542
    @brunaiglesias5542 2 ปีที่แล้ว

    This is some of the best content ever

  • @mgt6984
    @mgt6984 4 ปีที่แล้ว

    Thank you very for your lecture. It’s easier to understand than reading the book

  • @aleenakashif987
    @aleenakashif987 4 ปีที่แล้ว +5

    I love your lectures! Clarifying my concepts now after completing my med school lol. I wish i had found your lectures earlier. Love from 🇵🇰

  • @miladdulloo1997
    @miladdulloo1997 4 ปีที่แล้ว +6

    There is an error: ventilation is higher at the base than at the apex because of increasing compliance.
    The V/Q ratio is biggest at the apex because at the apex: Q higher is relatively to V.
    V/Q ratio is lowest at the base because V is higher comparatively to Q.

  • @tayyabakhan6632
    @tayyabakhan6632 4 ปีที่แล้ว +1

    This is really wonderful

  • @amandakling7815
    @amandakling7815 2 ปีที่แล้ว

    Love this guy. Such a good teacher!

  • @JCon_22
    @JCon_22 3 ปีที่แล้ว

    wanted to let you know Ninja Nerd. you have helped me so much man. literally could not get this down until i watched your video a few times. working toward the Flight Paramedic Certification which, there are no classes to teach the material just a book. so just wanted to let you know. HUUUUGE Help!! couldn't have done it without you.

  • @begumpasaoglu7641
    @begumpasaoglu7641 7 หลายเดือนก่อน

    the best channel for med students!!

  • @ghadeer5184
    @ghadeer5184 4 ปีที่แล้ว +2

    Mannnn you're the best and you're genius 😭♥️♥️ I really don't know how to thank you but you really help me in my studying.. ♥️ Hi from Iraq 🇮🇶

    • @egor7008
      @egor7008 ปีที่แล้ว

      طلع دكاترة العراق كسر 😂

  • @flynn8936
    @flynn8936 9 หลายเดือนก่อน +1

    27:15 !Ventilation is higher at the base of the lungs (in an upright position) due to gravity pulling on lung tissue which increases pleural pressure!

  • @shimab8898
    @shimab8898 2 ปีที่แล้ว

    Lots of love to you sir! You made this topic so much easier to understand 😀

  • @uswahmazhar8812
    @uswahmazhar8812 4 ปีที่แล้ว

    what a conceptual lecture it was.....well done....more power to you...

  • @frankbeattie7242
    @frankbeattie7242 2 ปีที่แล้ว

    I became a member and the extra notes are amazing thank you so much

  • @merraiii
    @merraiii ปีที่แล้ว

    Wow great video Zach

  • @hadiahassan8276
    @hadiahassan8276 5 ปีที่แล้ว +5

    You’re brilliant!

  • @adventurwithken412
    @adventurwithken412 6 ปีที่แล้ว +1

    You are just too much.Thank you so much for your help. God bless you.

  • @pavlinameldadube8895
    @pavlinameldadube8895 ปีที่แล้ว

    Thank you for the best lecture video and they are understandable

  • @abhishekgholap1300
    @abhishekgholap1300 3 ปีที่แล้ว +29

    28:00 . Isn’t Ventilation more at the base of the lung? Ref: Ganong’s

    • @akshitverma3328
      @akshitverma3328 3 ปีที่แล้ว +2

      The ventilation being talked abt is in the alveoli and not outside the alveoli..the ventilation will be more at the base but that phenomenon is applicable to the outside of the alveoli

    • @rachellugtu2776
      @rachellugtu2776 3 ปีที่แล้ว +4

      Ventilation and perfusion is higher at the base and lower at the apex of the lungs. However, V/Q ratio is higher at the apex and lower at the base.

    • @karthikeswaras2159
      @karthikeswaras2159 3 ปีที่แล้ว +1

      Yes due to gravity

    • @shayandin9709
      @shayandin9709 3 ปีที่แล้ว +1

      this doesnt make sense to me either

    • @shayandin9709
      @shayandin9709 3 ปีที่แล้ว

      @@rachellugtu2776 if the perfusion is lowest at the apex then whould the apex of the lung not try and match the ventilation therefore at the top of the lung would have a high ventilation?

  • @sajibahmed4121
    @sajibahmed4121 4 ปีที่แล้ว

    Sir, you teach us from the root of the topics that i love... Sir can u make a video on chest x-ray..there are many lectures on xray but all are boring....

  • @biotedlecture5133
    @biotedlecture5133 3 ปีที่แล้ว

    Love and a great respect from india .....very passionate teacher u r....bdw I m also a biology teacher 😊😊😊

  • @murtazaali4102
    @murtazaali4102 3 ปีที่แล้ว

    Thanks alot for making it easy to understand ...

  • @Fereshteh_Ranjbar
    @Fereshteh_Ranjbar ปีที่แล้ว

    Great job! Thanks

  • @ibysplumbingvideos9684
    @ibysplumbingvideos9684 4 ปีที่แล้ว

    Good video pal. Very well explained. Thanks.

  • @prashantpirthee2737
    @prashantpirthee2737 4 ปีที่แล้ว

    best teaching ever

  • @Un.knwn.saki6r
    @Un.knwn.saki6r 7 หลายเดือนก่อน

    Thought yall were capping but this a game changer fr

  • @TGNJared
    @TGNJared 4 ปีที่แล้ว +11

    Hey Zach, great video but wouldn't V AND Q be greater at the base compared to the apex (~28:00)? Pa > Pv > PA in Zone 3 so arteriolar perfusion pressure leads to good blood flow. For Ventilation, alveoli at the base have higher compliance and we would see an increase in ventilation for Zone 3 as well. Overall the the increase in Q > V so V/Q is decreased even though both are increased

  • @گمنامبسیجی
    @گمنامبسیجی 3 หลายเดือนก่อน

    Thank you professor God bless you❤

  • @ledamorales5079
    @ledamorales5079 5 ปีที่แล้ว

    you are the best teacher ever!!

  • @gabbyajok1178
    @gabbyajok1178 ปีที่แล้ว

    Thank you, Ninja Nerd. 💯

  • @himesama664
    @himesama664 4 ปีที่แล้ว

    Your videos are of great help! Keep it up. Man you're explanations are better than my professor who teaches 3hours🤣

  • @RachelP7911
    @RachelP7911 4 ปีที่แล้ว

    You da real MVP

  • @usama.r.rehman
    @usama.r.rehman 11 หลายเดือนก่อน

    Thanks 😊 sir for your efforts.

  • @Asma-rs1qz
    @Asma-rs1qz 4 ปีที่แล้ว

    you're really the best

  • @deanignatius750
    @deanignatius750 3 ปีที่แล้ว

    Love these lectures 💕

  • @aom.c9237
    @aom.c9237 6 หลายเดือนก่อน

    You just save my life!!!

  • @victoriagoetz9002
    @victoriagoetz9002 2 ปีที่แล้ว

    Thank you Ninja Nerd!

  • @Sprinklefrogzz
    @Sprinklefrogzz 11 หลายเดือนก่อน

    Thank you for this video❤

  • @giovannihenry1086
    @giovannihenry1086 3 ปีที่แล้ว

    Hey thanks for this video could you please assist and create a video on how an incentive spirometer works to prevent atelectasis?

  • @adrinpritamrai9312
    @adrinpritamrai9312 2 ปีที่แล้ว

    Great one.

  • @zainabsaleem1738
    @zainabsaleem1738 ปีที่แล้ว

    Such a great effort Sir 🙌💯

  • @hasnayakine7752
    @hasnayakine7752 4 ปีที่แล้ว

    Love your explanation 👏

  • @ikramkhelafi3721
    @ikramkhelafi3721 4 ปีที่แล้ว

    i like the way u teach with ! thank u for helping us

  • @letmedream111
    @letmedream111 2 ปีที่แล้ว

    amazingly helpful

  • @nishantjha3925
    @nishantjha3925 3 ปีที่แล้ว

    At the end of the video you said that the ventilation in upper part will be higher than the lower part of lung but in real the ventilation also increases from upper lobe of lungs to lower not so intensively as the perfusion but it does increases

  • @niraisubramani4640
    @niraisubramani4640 4 ปีที่แล้ว

    This helped me so much !! Thank you.

  • @ritikpandat316
    @ritikpandat316 ปีที่แล้ว +1

    Thanks ❤

  • @neet-py9sz
    @neet-py9sz 4 ปีที่แล้ว

    Ventilation increases from apex to the base. Please correct it ! Other than that ! A big fan ! Great job zack !

  • @sajiruddinsk8129
    @sajiruddinsk8129 4 หลายเดือนก่อน

    Excellent

  • @mashaelbamuqabel2734
    @mashaelbamuqabel2734 4 ปีที่แล้ว

    amazing explanation thanks a lot!

  • @abizewde336
    @abizewde336 4 ปีที่แล้ว

    Thank you so much

  • @hb6839
    @hb6839 6 ปีที่แล้ว +2

    You're a godsend!

  • @judahokonkwo3866
    @judahokonkwo3866 4 หลายเดือนก่อน

    Thanks Prof 🙇

  • @jigarthakker1880
    @jigarthakker1880 4 ปีที่แล้ว

    Amazing info and amazingly to taught...

  • @aimanjamil2344
    @aimanjamil2344 3 ปีที่แล้ว

    Thank You!!!!!

  • @kavyasb6484
    @kavyasb6484 3 ปีที่แล้ว +3

    That last part regarding the varying V/Q ratio due to gravity is troubling me..here's my doubt.
    A few minutes ago we learnt that the poor perfusion thing leads to poor ventilation too.
    Then how can the perfusion and ventilation be the opposite here in this scenario?
    If someone gets the question and proper explanation to my doubt...please do reply.That means a lot to me.
    Thanks.

    • @nyananguei1928
      @nyananguei1928 3 ปีที่แล้ว +3

      This is because, decrease in blood flow to alveolus decreases both oxygen and carbon dioxide Diffusion.
      Consequently, partial pressure of oxygen will increase while partial pressure of carbon dioxide deceases.
      Decrease partial pressure of carbon dioxide stimulates bronchioles smooth muscle to contact.
      This reduces oxygen wastage as it is churned into well perfused alveolus.
      In addition it reduces carbon dioxide expiration.
      Hence maintaining Normal ventilation ratio

  • @peshpraq5137
    @peshpraq5137 3 ปีที่แล้ว

    Many thanks
    You are the master.

  • @georgih1217
    @georgih1217 2 ปีที่แล้ว

    i love your videos so much