Intro to Running Molecular Dynamics Simulations with NAMD (links to each section in description)

แชร์
ฝัง
  • เผยแพร่เมื่อ 19 ธ.ค. 2024

ความคิดเห็น •

  • @GianmarcGrazioliPhD
    @GianmarcGrazioliPhD  9 วันที่ผ่านมา

    Since people often have issues getting VMD to work in the terminal, I created this video recently: th-cam.com/video/lWPZAHQiTSs/w-d-xo.htmlsi=woZ44UP1dDg6UI2U

  • @setyantotriwahyudi4322
    @setyantotriwahyudi4322 3 ปีที่แล้ว +2

    Thank you Dr. Gianmarc .. Great Tutorial

  • @nickjojo4623
    @nickjojo4623 2 ปีที่แล้ว

    i can't change the directory in tkconsole even though it works for command prompt/terminal. Please help

  • @RAHULSINGH-bk3nf
    @RAHULSINGH-bk3nf 2 ปีที่แล้ว

    I am getting error for TCL namdcph
    Kindly help me to solve this problem.

  • @Neuronworld
    @Neuronworld 2 ปีที่แล้ว

    how to apply External electric field ON A Molecule using NAMD/ VMD

  • @oktavialisti172
    @oktavialisti172 3 ปีที่แล้ว

    Hi sir, thank you for the video. I saw on the namd input script, you wrote run 2500, what is unit for that sir? does it show a step or what? for example, the step will be moved every 2 ps. meaning that the total simulations time is 2500 x 2 ps= 5000 ps?

  • @ongunpalaoglu3688
    @ongunpalaoglu3688 2 หลายเดือนก่อน

    can someone please help me, ı am unable to run text mode for vmd. it gives -bash: vmd: command not found. vmd -dispdev text -e ubq.pgn with this code on mac

    • @GianmarcGrazioliPhD
      @GianmarcGrazioliPhD  หลายเดือนก่อน

      If you can open VMD with the mouse but not using ther terminal, then it sounds like maybe you don't have a correct alias for the vmd command in your ~/.bash_profile or ~/.bashrc file. I'm not 100% sure this is your issue, but I've seen students have symptoms like this before. VMD used to create the alias for you upon installation, but it doesn't seem to always happen automatically now. Good luck!

  • @krishnakumarpatel4079
    @krishnakumarpatel4079 3 ปีที่แล้ว +2

    Can't thank you enough! You are a hero.

    • @GianmarcGrazioliPhD
      @GianmarcGrazioliPhD  8 หลายเดือนก่อน

      I’m so glad it was helpful, thank you for your message!

  • @dianaa.valencia3910
    @dianaa.valencia3910 3 ปีที่แล้ว

    Hello. If I want to make a long simulation (100 ns) for publishing and also a docking, is this procedure appropriate? Or more steps are required? Thanks.

  • @ikponwmosaobaseki3645
    @ikponwmosaobaseki3645 3 ปีที่แล้ว

    what if u have multiple protein chains, will you run psfgen for each chain? if u do that you will have different pdb files how can u merge that?

    • @mudgalsdiary
      @mudgalsdiary 3 ปีที่แล้ว

      Google topotools mergemol VMD, you will get a TCl script. You can use that to merge them.

    • @ikponwmosaobaseki3645
      @ikponwmosaobaseki3645 3 ปีที่แล้ว +1

      @@mudgalsdiary thanks

  • @1998neet
    @1998neet 3 ปีที่แล้ว

    Can ubuntu have access such as discovery studio, molecular docking gold?

  • @anushkamahajan8186
    @anushkamahajan8186 3 ปีที่แล้ว

    Hi Sir,
    If I'm heating my system periodically from 0K to 300K, do I need to use Langevin Dynamics?
    What would happen if we don't use Langevin dynamics in NAMD config file?

  • @shovansarker5403
    @shovansarker5403 3 ปีที่แล้ว

    What temperature should I choose while designing drug for human? Some say it should be 310k as human body temperature other say 300k.

    • @dianaa.valencia3910
      @dianaa.valencia3910 3 ปีที่แล้ว +2

      I've seen 310 K in many works, so I think it'll depend on your system. But I guess all the simulations try to be closest to real as possible.

    • @ALEJO29905
      @ALEJO29905 3 ปีที่แล้ว +1

      It should be 310k. It's a human body temperature.

  • @manjari3112
    @manjari3112 3 ปีที่แล้ว

    hello sir, thanku your tutorial helped me in simulating my protein with ligand. Is it possible to simulate one protein with multiple ligands using NAMD? Please reply.

  • @maralafshinpour5539
    @maralafshinpour5539 2 ปีที่แล้ว

    Hi , Is there any tutorial for NAMD qm/mm?

  • @dianaa.valencia3910
    @dianaa.valencia3910 3 ปีที่แล้ว

    Hello. Which version of NAMD do you have?

  • @ikponwmosaobaseki3645
    @ikponwmosaobaseki3645 3 ปีที่แล้ว +1

    Thanks for this you really helped me

  • @farhadzrarahmed1819
    @farhadzrarahmed1819 2 ปีที่แล้ว

    Hello Sir. your video is really helpful, thanks. l am a new user MD simulation using LAMMPS packages. If you know about running a system using LAMMPS instead of NAMD and could be described it in a short video. I would be very appreciated it.

  • @abhiban66
    @abhiban66 ปีที่แล้ว

    Thanks for posting.

    • @GianmarcGrazioliPhD
      @GianmarcGrazioliPhD  8 หลายเดือนก่อน

      You are very welcome, thank you for your message!

  • @joaoluismossri7526
    @joaoluismossri7526 3 ปีที่แล้ว +1

    Thanks a lot, Sir! That was very helpful!

  • @paulocarvalho5688
    @paulocarvalho5688 ปีที่แล้ว

    Thanks for the video. Could you make a video teaching how to enable the GPUs? Additionally, could you do a simulation with one GPU and then with more than one GPU? Will simulation with more than one GPU be faster than with just 1? If the result is the same, how do you configure NAMD to use all GPUs?

  • @meitadea3765
    @meitadea3765 3 ปีที่แล้ว

    hello sir, is this the overall design of molecular dynamics?

    • @GianmarcGrazioliPhD
      @GianmarcGrazioliPhD  3 ปีที่แล้ว +1

      This is a demo where I am running through a tutorial specifically for the NAMD molecular dynamics software package.

    • @godwinir712
      @godwinir712 3 ปีที่แล้ว

      @@GianmarcGrazioliPhD Respected sir..I couldnt acess into the Charmm Gui web server from my personal mail and I am not provided with affiliation mail..could you please help me out..?Or is there another way to generate files..?

  • @bettygao2704
    @bettygao2704 3 ปีที่แล้ว +1

    thanks!!!

  • @castilloh.gianmarco1048
    @castilloh.gianmarco1048 7 หลายเดือนก่อน

    gozuuu

  • @zainabahsan2369
    @zainabahsan2369 3 ปีที่แล้ว

    Showing this problem during MD_Run.namd Info: USING ARITHMETIC MEAN TO COMBINE L-J SIGMA PARAMETERS FATAL ERROR: UNKNOWN PARAMETER IN CHARMM PARAMETER FILE ./toppar_water_ions.str LINE=*set nat ?NATC* FATAL ERROR: UNKNOWN PARAMETER IN CHARMM PARAMETER FILE ./toppar_water_ions.str LINE=*set nat ?NATC*