Khan academy never fails to amaze me. Thank you for presenting this topic in a way that is simple and easy to understand, and with awesome graphics that really help drive the point home! I don't think I could make it through nursing school without these amazing videos!
correction : with increase preload there is left ventricular hypertrophy due to volume overload and that's eccentric hypertrophy so heart chambers will get enlarged . and due to increase afterload the hypertrophy is concentric and with that heart chambers get smaller . overall a very good video for learning
So why do we treat heart failure with ace inhibitors which remove fluid from the body? According to this video, fluid is needed to increase preload and increase heart contractility.
Let me try to answer this question to the best of my knowledge. I can see why you asked this and I understand your thought process. ACE (angiotensin converting enzyme) inhibitors are primarily used to treat hypertension and heart failure. They don't necessarily have much of a diuretic effect, in fact they are k-sparing. About the fluid..our body already has anti-diuretic hormones, as mentioned in the video, that help with fluid fill up in the ventricles. That hormone (ADH) prevents fluid from leaving the body, so we don't necessarily need more fluid to have increased pre-load. We already have it by preventing diuretic effect. We do give diuretics to HF patients though, such as loop and thiazide diuretics. They come in to play mostly with decompensated heart failure to "suck" out the fluid build up throughout the body.
The renin system allows Na and Water retention because the body believes that it needs to hold on to more fluid because it is not getting enough blood/fluid/o2. It is trying to compensate. RAAS releases ADH, which helps increase the fluid volume that is then needed to increase the pre-load.
Preload is the volume of ventricles in resting state, right before they contract. In this stage ventricles are "loading" up/ filling up with blood before they can pump it. AND yes you are correct in that afterload is more of a pressure. Afterload is correlated with contraction, the shooting if you will, of blood from ventricles.
pumping more blood with hypertrophy produces more extra oxygen than it uses seems pretty obvious so that does not explain decompensation. It's also obviously the underlying cause that keeps making things worse and the cardiologists only knowing about the heart but nothing else in the body.
Hlo i have diagnosed hypertension concentric lvh and preserved lv function is it heart failure am only 22 year old please help me any one know what is it
It's really not elasticity so much as optimization actin-myosin cross-bridge alignment that increases force of contraction in stretched heart muscle, producing the Frank-Starling effect.
Khan academy never fails to amaze me. Thank you for presenting this topic in a way that is simple and easy to understand, and with awesome graphics that really help drive the point home! I don't think I could make it through nursing school without these amazing videos!
Thanks I am an 11 year old kid and I really want to be a cardiologist. It is much better than waiting until college and medical school :) .
go for it...
I'm Impressed keep it up and keep on learning brother 🤍
Currently in med school! See you in the hospital in 10 years!
I love the " help me move" analogy. I'm sending this to my son.
HIS VOICE IS OSMOSIS VOICE!!! lol. thank yoooouuu very much khan academyyy!!
omggggg
Yesss I noticed 😂😂😂
Right
:O
That friendship analogy about moving was spot on, I really pictured the receptors in that sense. Thanks mate✌️
Wow, this is a KHAN’S Video with OSMOSIS Flavor 👍😊
I think it's the same guy
@@kokocipher Yes, he is.
Thank you for presenting such an easy-to-understand video!
PERFECT EXPLAINATION. ITS JUST MADE MY MIND SO CLEAR!
Amazing explanation! Thank you!
Perfect video and great explanation!!! Really appreciate Khan Academy's videos. Life savers 🥰
The analogy was great!
Omg thank you for making this video!!!
Great explanation and illustrations. Thank you.
explained very well. its like crystal clear explanation. thanks
correction : with increase preload there is left ventricular hypertrophy due to volume overload and that's eccentric hypertrophy so heart chambers will get enlarged . and due to increase afterload the hypertrophy is concentric and with that heart chambers get smaller . overall a very good video for learning
Wonderful as usual
Amazing explanation, voice and analogy, only 1 thing: plz do it on a white background with bigger letters, and you will be the best on the whole tube
Thank you
This was an awesome explanation, thank you.
thank you so much! you explained it too clearly!
Really amazing explanation
Wish my nursing instructors taught this well.
great explanation. Thanks Khan acadamy
thank you thank you tnank you very very much 🤩🤩❤️❤️❤️❤️❤️❤️❤️❤️❤️
Great video! (Frank and Starling were 2 different guys)
thank you!
Well explained superb
just one word perfect
I know his voice anywhere!!!! #Osmosis 💜
Wonderful just wonderful.
Thank you! And great job teaching!
Excellent!
thank you a lot👍
Amazing!!!
Great
Thanx very match
U helped me alot
Muchas Gracias!
Good information
thank you so much! 5/12/2022
incredible thanks man :)
osmosis guy on khan??? great combo
thankyou so much , now i get it
MY OSMOSIS MAN! ♥️
you sir are a legeeeennd
What a cute bear!
So why do we treat heart failure with ace inhibitors which remove fluid from the body? According to this video, fluid is needed to increase preload and increase heart contractility.
Let me try to answer this question to the best of my knowledge. I can see why you asked this and I understand your thought process. ACE (angiotensin converting enzyme) inhibitors are primarily used to treat hypertension and heart failure. They don't necessarily have much of a diuretic effect, in fact they are k-sparing. About the fluid..our body already has anti-diuretic hormones, as mentioned in the video, that help with fluid fill up in the ventricles. That hormone (ADH) prevents fluid from leaving the body, so we don't necessarily need more fluid to have increased pre-load. We already have it by preventing diuretic effect.
We do give diuretics to HF patients though, such as loop and thiazide diuretics. They come in to play mostly with decompensated heart failure to "suck" out the fluid build up throughout the body.
Why then is it beneficial to exercise? Since that would increase compensation and decompensation?
Good explanation but the Frank-Starling law is named after two people: Otto Frank and Ernest Starling.
The ICU handbook
i think you also can use shepherd and wolf as an analogy
YA'LL THANK YOU :(( I'LL GET THROUGH MY CARDIO MODULE BCOS OF YA'LL
This guy 'Frank Starling'.
Its Frank and Starling isn't it?
What about after load??
How would the RAAS system work as a compensatory system in HF?
The renin system allows Na and Water retention because the body believes that it needs to hold on to more fluid because it is not getting enough blood/fluid/o2. It is trying to compensate. RAAS releases ADH, which helps increase the fluid volume that is then needed to increase the pre-load.
Isn’t preload the volume after filling, I thought afterload is pressure?
Preload is the volume of ventricles in resting state, right before they contract. In this stage ventricles are "loading" up/ filling up with blood before they can pump it. AND yes you are correct in that afterload is more of a pressure. Afterload is correlated with contraction, the shooting if you will, of blood from ventricles.
pumping more blood with hypertrophy produces more extra oxygen than it uses seems pretty obvious so that does not explain decompensation. It's also obviously the underlying cause that keeps making things worse and the cardiologists only knowing about the heart but nothing else in the body.
Hlo i have diagnosed hypertension concentric lvh and preserved lv function is it heart failure am only 22 year old please help me any one know what is it
Good content but pinching fast voice
I got social anxiety from an analogy XD
Osmosis
better than osmosis
I miss the old Osmosis
Is this the guy from osmosis?
Yes
the osmosis guy's voice shocked me
👍👍👍
So osmosis like
idk why but i feel sorry for that cardiac cell 6:11 😫😫
It's really not elasticity so much as optimization actin-myosin cross-bridge alignment that increases force of contraction in stretched heart muscle, producing the Frank-Starling effect.
This is the guy from osmosis 😂❤️
👌👍🏻
Haaaay osmosis guy!!!
Slow down lil bit
2:32 No.
You talk wayyyyyyy tooo fast...slow down and let people understand what you are saying, its hard to keep up when your going at 10000mph.