Eddy's Hot Plate Analgesiometer | To Study the Analgesic Activity of Given Drug (

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Pain- pain is an unpleasant feeling, which makes us uncomfortable and reduces the physical as well as mental alertness. Although pain is also useful for us because it acts as a warning signal and it warns about something uncommon inside or outside our body. If the pain is minor it may be tolerated but if the pain becomes severe it has to be managed at earliest.
Analgesic- Analgesics are the drug which is used to get relief of pain. Although there is no such drug which completely removes or reduce the pain by its root. The analgesic drug only suppresses the sensation of pain or increase the threshold of it. The reason for pain perception is the genesis of cyclooxygenase (COX). COX is of 02 main type- I and II. The main target for NSAID (non-steroidal anti-inflammatory drugs) is to selectively inhibit the COX-II
In the hot plate method, we use heat as the main stimulus or source of pain. Mice are the choice of animal for these experiments. The hot plate is a device having boundary on the outer side and a plate which get heated by a heating coil from inside. Mice are placed one by one on this apparatus (hot-plate) which temperature is kept constant by a regulator, that is around 55-degree centigrade and the licking the paw, jumping reaction of animal are recorded as the endpoint of the experiment. Analgesic increase the reaction time. Eddy and Leimbach were the first to describe this method in 1953 so this apparatus is also known as Eddy’s hot plate.
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[@tarunsolanki6177]

Sir aap hamare liye jo mehnat kar rahe like theroy+practicals+ with notes 🙏🙏🙏🙏🙏
V.v.v. very tq sir

[@solutionpharmacy]

My pleasure tarun ji

[@bhavyajain26912]

Thanku sir to explain this practical😊👍

[@vandanasharma8027]

Yes sir ....we want more videos like this.....it is very helpful to us ....

[@solutionpharmacy]

Sure. I will upload more

[@vandanasharma8027]

Thankuuu sir.....

[@asifmehmood5819]

Mice ko kitni seconds k leyi rkna hai? Hot plate pai?

[@mahadevshinde3427]

Wonderful sir

[@solutionpharmacy]

Thank you

[@ShabirAhmed-ov3ql]

Thank you so much Sir for this experiments....,,🙏🙏

[@solutionpharmacy]

Shabir Ahmed my pleasure

[@asohkkanujiya3396]

No

[@vidyasahare8038]

It's really Helpful to us☺️

[@sikendrakumar9510]

Thank you so much sir for this experiment

[@solutionpharmacy]

sikandra gupta my pleasure

[@jeetu447]

Thank you so much ❣️❣️❣️

[@juliyadav361]

Nice sir...

[@nancysahusahu370]

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[@solutionpharmacy]

Nancy Sahu Sahu thank you

[@sakshivaidya7069]

Thanku very much sir for thr practical

[@solutionpharmacy]

My pleasure

[@juliyadav361]

Thank you sir

[@shaikh3667]

Great explanation sir

[@solutionpharmacy]

Shaikh Zubair thank you

[@prachipandey8683]

Thank u sir..it is very useful for us..😊

[@solutionpharmacy]

Thank you

[@CHILL-sq7lm]

Thanks your sir

[@pharmacistaltamashansari6668]

Very useful video sir

[@solutionpharmacy]

Thank you

[@Raghav563]

Very nice explain sir u so great teacher

[@solutionpharmacy]

Thank you

[@mr.market6802]

Tq sir ji

[@solutionpharmacy]

Welcome dear.

[@shortskakeeda101]

Thank you sir 🙏

[@solutionpharmacy]

Welcome

[@alphagonist4748]

Helpful

[@solutionpharmacy]

nitdsu thank you

[@nishantsen6820]

House keeping sir? What is it

[@solutionpharmacy]

Means it provide safety to out body in specific aspect

[@PrinciThapak_scienceelite]

Sir percent analgesic activity kaise nikalna hai??

[@solutionpharmacy]

Kine animal pr kitna asar hua

[@sourabhkumar6633]

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[@solutionpharmacy]

SOURABH KUMAR 3 sem me cology nahi hai

[@prchandrakar6982]

Sir 3rd semester ka notes chahiye tha

[@solutionpharmacy]

Pokhraj Chandrakar sorry i dont teach 3 sem

[@prchandrakar6982]

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Pokhraj Chandrakar sanjivni kaha hai

[@prchandrakar6982]

CVITS exam dilane gaya tha to apka aur mam ka dute tha waha Sir ji

[@solutionpharmacy]

Pokhraj Chandrakar ok. Got it. Mai kosis akrunga. Aapko channel
Ke baare me kaise pata chala ?

[@somethingnew4Uu]

Totally bakwas

[@solutionpharmacy]

Thank you for your feedback. Kindly provide your valuable suggestion.

[@Lvmyself_]

Thank you sir

[@solutionpharmacy]

My pleasure