Schools should pay big $ if you were an instructor lol. If more teachers were as good at this as you were, I'd say 95% of us would have A's on our exams. Thanks!
Haha thanks Benhart Jugo! Yeah that's my dream for everyone taking Orgo to actually learn it and not be weeded out having learned nothing. I hope one day I can find a position that pays well for this :]. In the meantime in case you or any of your friends were interested in donating a few bucks to support my videos and me the link is right here: goo.gl/ZpohrU. Thanks again for the positive feedback!
My mind was blown when you said not to make Br leave first. My professor always drew that arrow first and I never understood why. He just said because it's the leaving group, and me and my classmates are just like "ooookkay...". But Now the backside concept/rule makes perfect sense now! Thanks!
And OF COURSE I like your videos and explanation because it's not just making to memorize stuff for each mechanism. It makes me to think and understand the concept. THANK YOU TONS! :)
Ah that's a really good point actually, I will definitely keep that in mind. Maybe I'll include it if I remake this video or perhaps I'll make a separate video showing that. But if you try it out with one with a actual chiral center and apply the rules in my R/S Video you should be able to see R->S or S->R occuring. Give it a try with one or two problems and tell me if it works ;)
Ah, thank you so much! I was having a lot of troubles with inversion and retention and it helped so much to hear why it was important to have primary and tertiary carbons!!
+Clara Ibrahim Awesome! I'm glad to hear that Clara! Here's the link to some other awesome resources as gift for leaving the comment! :] (orgomadeeasy.org/extra-resources/) Keep working hard!
My prof taught SN2 reactions as an umbrella being caught in the wind and inverting to describe the inversion. It was useful to help visualize the transition state with the nucleophile and leaving group facing left and right and the other 3 groups being in one plane
Thank you so much for the kind words and support :). Your welcome a TON for watching and giving me feedback ;). I'm glad I can get you thinking critically haha. Be sure to share my video with your classmates too, thanks again!
The reason why I'm asking is that I was confused with one question from my textbook. It said "Optically active 2-bromobutane undergoes racemization on treatment w/ a solution of KBr. Give a mechanism for this racemization". I only thought about Sn1 reaction by looking at the word, "racemization" however, the mechanism was actually Sn2. Can you plz explain about it?
Do you mean for the substrate? And if the Br was in the back? In that case, you would attack the molecule from the front and the CH3O would be in the wedged position. Hope that answers your question. :)
Haha that's awesome to hear! (your username is hilarious btw) Those lightbulb moments when things finally just click are the best. Hope you ace any Substitution questions now :]
Crystal Asplund Thanks for the feedback! I'm glad they can clear things up for you. :D if you'd like to be updated more reliably because TH-cam's subscription service isn't so great, you can follow me on Patreon now. :] (It's 100% free to just follow, but if you do decide to support me via there I would be super grateful.) www.patreon.com/OrgoMadeEasy
For Sn2 reaction, when you put a note on a side "If inversion occurs, (R)->(S) or (S)->(R)", it would've been good if you had more detail about it with an example. Because yours didn't have a chiral center, right?
Hello I see that you sometime have it written as h3c and sometime ch3. So it's ultimately the same thing correct no matter what order you have it written
great video thanks a lot. i was just wondering whether it was important on not to stress about the pentavalent carbon transition state that is formed during the SN2 reaction as i was taught about this but noticed you didnt mention it. is it therefore not important? thanks
sonia starks ***** is actually holding a free online webinar on those aromatic benzene reactions this sunday @8pm EST, if you'd like some additional help. :] leah4sci.com/orgomadeeasy
u told dat in sn2 there is a backside attack due to less crowding as compared to sn1 where the teritary carbon does not let it do so....but down you wrote in sn1 that there is a 50-50 chance of frontside and backside attack.....if there is the crowding of carbons how can it let it attck backside....give me some example of backside attack in sn1 plzzz
Ah okay so every single Sn1 reaction can occur via a frontside or backside attack because after the first step in which the leaving group leaves the molecules structure becomes sp2 hybridized so trigonal planar and almost flat. Therefore there's no real preference in which side the nucleophile comes in and attacks. Note the transition state at 1:28 of this video. :] SN1 Reactions
I'm pretty sure there's only inversion if and only if the carbon is a stereogenic center. therefore, I don't think you had to do an inversion of configuration.
Remus Mocanu That's a good point Remus. Yup you only need to worry about a flip in R and S if there is even a chiral center there in the first place. So primary carbons like in my example wouldn't experience an inversion of R or S, but secondary carbons could since they can actually be chiral centers. Good observation!
my nigga youre coming in clutch when i needed you da most good shit playa
The length is perfect. Thank you!
+Green Marble Sweet! Good to know! #NoProblemoo
Schools should pay big $ if you were an instructor lol. If more teachers were as good at this as you were, I'd say 95% of us would have A's on our exams. Thanks!
Haha thanks Benhart Jugo! Yeah that's my dream for everyone taking Orgo to actually learn it and not be weeded out having learned nothing. I hope one day I can find a position that pays well for this :]. In the meantime in case you or any of your friends were interested in donating a few bucks to support my videos and me the link is right here: goo.gl/ZpohrU. Thanks again for the positive feedback!
My mind was blown when you said not to make Br leave first. My professor always drew that arrow first and I never understood why. He just said because it's the leaving group, and me and my classmates are just like "ooookkay...". But Now the backside concept/rule makes perfect sense now! Thanks!
I just can't describe how amazing your videos are!!!
Thank you so much you helped me a lot , you can make anything difficult to understand very easy.
Thanks for the support! Appreciate you taking time out to comment, it's very motivating :D
Very helpful. I like your corny jokes, they made my day!
Thank's this is all clear for me now ! I'm from Switzerland and your explanations are perfect and clear for a french speaker ! Definitely subscribed .
And OF COURSE I like your videos and explanation because it's not just making to memorize stuff for each mechanism. It makes me to think and understand the concept. THANK YOU TONS! :)
this is perfect! I understood everything! Thanks a lot! And your jokes make it even more interesting!
Thanks Garima!! That's awesome to hear haha :D Students like you make the time I put in to make these videos all worth it!
Garima Sharma
Ah that's a really good point actually, I will definitely keep that in mind. Maybe I'll include it if I remake this video or perhaps I'll make a separate video showing that. But if you try it out with one with a actual chiral center and apply the rules in my R/S Video you should be able to see R->S or S->R occuring. Give it a try with one or two problems and tell me if it works ;)
Ah, thank you so much! I was having a lot of troubles with inversion and retention and it helped so much to hear why it was important to have primary and tertiary carbons!!
No problem! Thanks for taking time out to comment, hope you can share this vid with your friends too ;). Best of luck!
Using the visual molecules and analogies helped soon much! Thank you! Thank you! Thank you! Definitely subscribed!
+Clara Ibrahim Awesome! I'm glad to hear that Clara! Here's the link to some other awesome resources as gift for leaving the comment! :] (orgomadeeasy.org/extra-resources/) Keep working hard!
My prof taught SN2 reactions as an umbrella being caught in the wind and inverting to describe the inversion. It was useful to help visualize the transition state with the nucleophile and leaving group facing left and right and the other 3 groups being in one plane
You made my day dude! thanks for the clear instructions :)
Thank you so much for the kind words and support :). Your welcome a TON for watching and giving me feedback ;). I'm glad I can get you thinking critically haha. Be sure to share my video with your classmates too, thanks again!
you're awesome, i finally understand it now. Thank you so much !!
Wooot! Awesome to hear. :] And P.S. nice thumbnail, Supernatural Ftw!
Thank you so much sir now my doubts are clear
I wish I wouldve watched this before my last test!
The reason why I'm asking is that I was confused with one question from my textbook. It said "Optically active 2-bromobutane undergoes racemization on treatment w/ a solution of KBr. Give a mechanism for this racemization". I only thought about Sn1 reaction by looking at the word, "racemization" however, the mechanism was actually Sn2. Can you plz explain about it?
Do you mean for the substrate? And if the Br was in the back? In that case, you would attack the molecule from the front and the CH3O would be in the wedged position. Hope that answers your question. :)
Haha that's awesome to hear! (your username is hilarious btw) Those lightbulb moments when things finally just click are the best. Hope you ace any Substitution questions now :]
I dont know why after I watched your videos, I am really mad on my teachers now!!
Thank you so much. Your parábolas (I don't remember the English) make so much sense!
Thank you for your videos! They have been really helpful!
Crystal Asplund Thanks for the feedback! I'm glad they can clear things up for you. :D if you'd like to be updated more reliably because TH-cam's subscription service isn't so great, you can follow me on Patreon now. :] (It's 100% free to just follow, but if you do decide to support me via there I would be super grateful.) www.patreon.com/OrgoMadeEasy
So the CH3O- , nucleophile has just one extra electron? And thats the electron that it will be sharing with the carbon to form the covalent bond?
For Sn2 reaction, when you put a note on a side "If inversion occurs, (R)->(S) or (S)->(R)", it would've been good if you had more detail about it with an example. Because yours didn't have a chiral center, right?
Hello I see that you sometime have it written as h3c and sometime ch3. So it's ultimately the same thing correct no matter what order you have it written
Recommended you to all my friends keep it up!!!!
Thanks iman! I reeaally appreciate it. :] Good luck with your studies!
very easy to understand thanks!
great video thanks a lot. i was just wondering whether it was important on not to stress about the pentavalent carbon transition state that is formed during the SN2 reaction as i was taught about this but noticed you didnt mention it. is it therefore not important? thanks
Great video series, thank you!
im having trouble with aromatic benzene sn1 /sn2 do you cover that as well?
Hi Sonia, sorry I haven't gotten a chance to cover those concepts yet. =/
sonia starks ***** is actually holding a free online webinar on those aromatic benzene reactions this sunday @8pm EST, if you'd like some additional help. :] leah4sci.com/orgomadeeasy
Yes. Thank you
oh my gosh, you are amazing so so so much gratitude
You're funny and very helpful! Thanks
u told dat in sn2 there is a backside attack due to less crowding as compared to sn1 where the teritary carbon does not let it do so....but down you wrote in sn1 that there is a 50-50 chance of frontside and backside attack.....if there is the crowding of carbons how can it let it attck backside....give me some example of backside attack in sn1 plzzz
Ah okay so every single Sn1 reaction can occur via a frontside or backside attack because after the first step in which the leaving group leaves the molecules structure becomes sp2 hybridized so trigonal planar and almost flat. Therefore there's no real preference in which side the nucleophile comes in and attacks. Note the transition state at 1:28 of this video. :] SN1 Reactions
This is the video I mentioned: SN1 Reactions
I'm pretty sure there's only inversion if and only if the carbon is a stereogenic center. therefore, I don't think you had to do an inversion of configuration.
Remus Mocanu That's a good point Remus. Yup you only need to worry about a flip in R and S if there is even a chiral center there in the first place. So primary carbons like in my example wouldn't experience an inversion of R or S, but secondary carbons could since they can actually be chiral centers. Good observation!
For SN2 reactions, what happens if the methyl group isn't on the back of the molecule? What if it was on the front or something?
I was following your comments and videos you seem to me very versed of what you say..such a funny chemist you are ^_^
Thank you very must ....i understand same point now!
You're awesome.
Haha you're too kind, your welcome. I hope SN2/SN1 reactions were made easier for you! ;)
Thank you very much!!!
bless your soul
But why are u showing stereochemistry on the carbon, it isn't chiral?
Thanks !
You sir, just got my subscription =)
Thank you so so so soso so much! There is hope
There definitely is! :] Good luck
You are great
why you say orgo, there isn't a second o in organic >.>
Haha that's what we call it here in Boston/ the Northeast US.
Okay I found an explanation for this and I'll msg it to you because I'm not allowed to put links in the comments section haha.
You sir, just got my subscription =)
Sweeeet! ;)