You're an amazing instructor! Explained the concepts easily, enthusiastically, but also added important caveats that really solidify my understanding! Thank you
I just learned more about Starling's law of the capillaries from this video than from my lecture class. Thank you for putting the time into making this video!
I'm not a native speaker and although I usually don't have any trouble understanding what's being said, I sometimes have a hard time "feeling" the topic since the language just doesn't feel 100% natural. But your way of explaining things is somehow just perfect for me, you're so easy (and dare I say fun or is that weird because we're trying to learn something here? :p ) to listen to! This is perfect for me, thank you.
Wow this video was so helpful. Best explanation of oncotic/osmotic and hydrostatic pressure in relation to the capillaries I've seen so far. Thank you!
Thank you so much. It's clear for a non-native speaker as me. Somehow it helps perfectly on my understanding about the inflammation process in the pulp cavity. Thanks! from Viet Nam
OMG....LOVE THIS VIDEO SO MUCH REALLY HELPS...PRENURSING STUDENT WITH 3KIDS STUCK IN HOME DURING THIS PANDEMIC ..CAN CAUSE FOR EXTRA HELP..ALL ONLINE CLASSES SO THIS VIDEO REALLY HELPS.. SOMETIMES THESE CONCEPTS CAN BE TRICKY BUT HELPS WHEN U HAVE FULL KNOWLEDGE ..THANKS SO MUCH
I really appreciate your video!!! I'm currently taking an online A&P course and there's no lecture time. This video really breaks everything down and I like that you mentioned oncotic pressure and instead of colloid solution it's technically molecular Thank you for taking the time to share this!
This was such a great help! Thanks for clarifying my IB Biology doubts. I do have a question. It wasn't clear to me how exactly the lyphatic system keeps the interstitial hydrostatic pressure at about a 0.
My review list 4 different pressure. My understanding is glomerular blood hydrostatic pressure pushes fluid out of glomerulus while capsular hydrostatic pressure pushes fluid back into the glomerulus. What I don't quite get is the difference between blood colloid osmotic pressure and capsular colloid osmotic pressure. Does blood colloid prevent water from leaving while capsular colloid pushes water out? I hope you still respond to this post! Your explanations are very helpful! Thanks!
+Brittany Jaramillo In the video above, we're discussing pressures in capillaries in general. The glomerulus is a modified capillary, and of course there are some special circumstances there that don't necessarily apply to other capillaries in the body :). To answer your question, the colloid pressure exerted by the blood "holds" water in the capillary (more protein staying in the blood will draw water into the glomerulus), while capsular colloid pressure will draw water out of the glomerulus and into the capsule. Hope that helps!
This video saved my life!! thank you so much you did an awesome job! keep up the great work!!!!!! also you have a lovely voice unlike my teacher who is so monotone and boring.
Wow - just wow! Please do not take this the wrong way...please. I have hardly ever heard anyone, let alone a woman, explain something in such a concise and informative way without coming across a litlle full of themselves. Half-way through I subscribed! What a pleasure to have found your channel - it's 11:45 and I need sleep... but I will be back!!!
Is the osmotic pressure drawn in the diagram that of the interstitial fluid? You mentioned the osmotic pressure being a counter pressure to the direction of water moving towards a higher concentration of solutes ie. Blood components in this video example
Thank you for the excellent presentation, I wonder ,however, about the kinds of physiological changes that would occur at within such a space if a lateral force of negative pressure were applied over these tissues from the outside as happens during dry cupping..some estimate that a negative vacuum between -150 and 450mmhg may be created...I will be most grateful if you consider my request for an explanation
Hi, I'm currently doing pre-med and in my summarised notes, it's stated that fluid is drawn out at the interstitial fluid colloid osmotic pressure at 5mmHg, is this referring to the terms you use of fluid coming in because of the low hydrostatic pressure at the venous ends? Could you please clarify, thank you! Enjoyed your video!
Hey, great video! Finally understood how the capillary microcirculation works. Just one doubt though: interstitial colloid pressure tends to bring fluids from the capillary toward the interstitium while interstitial hydrostatic pressure bring fluids inside the lymphatic system? Thank you in advance :)
I have a question. I have read that a high salt diet should not affect lymphedema, because lymphedema is not due to osmotic pressure, but rather oncotic pressure. Is this true? Can you explain this? Thank you.
Thank you for this. Can you do video with starlings principle updated to show that in fact it's a net filration out of the capillaries and not reabsorption? Compare and contrast? Thank you!
Ah I still don't get what oncotic pressure is - everywhere it is mentioned that it is the pressure exerted to PREVENT any more water absorption - what does that mean exactly, what exerts that pressure? It implies the two different solutions must already attain some sort of equilibrium just like in that sugar water example. Thank you!
can the diameter of a capillary change ? or are there various sizes of the diameter of capillaries ? naturally vessels expand and contract , are rbc's single file at any point in capillaries concerning volume of serem in comparison to serem in for example the venous cavious? how condensed are rbc's in the left atrium or left ventricle?
Great video! We learnt about this in class. I wasn't sure what was the exact reason as to why the hydrostatic pressure of the interstitial fluid remains 0. We learnt that the interstitial fluid can be slightly negative or 0. Could you please tell me why?
awesome vid. so since RBCs, WBCs and plasma proteins can't leak thru, is it fair to assume something like a histamine or prostaglandin is going to affect the oncotic pressure since prostaglandins/histamines increase cell wall permeability, thus allowing the bigger molecules to leak thru, and therefore increasing oncotic pressure?
+oopalonga Yes, it depends on the local milieu, and generally anything that increases capillary permeability and promotes movement of WBC out of the vasculature and into the tissue will increase the interstitial oncotic pressure
I cannot understand the reason behind the relation between vasodilation and increased hydrostatic pressure. If hydrostatic pressure is the pressure opposed on the wall of the vessel, vasodilation should in fact decrease hydr. pressure not vice versa. Or is the dilation always accompanied with relatively more flow (diameter/flow relativity)? Robins says "Vasodilation increases flow thus increasing hydrostatic pressure".
Hi . You've done a great job . But could you explain me what is the role of Albumins in this case . I'm learning that they prevent edema but how this happens . Thank you :)
+Altin Izairi Albumins are produced in the liver and are the most abundant protein found in the blood. Because they are quite large, they cannot easily cross the capillary membrane. By staying behind in the blood they draw water towards them (oncotic pressure) and keep fluid in the blood rather than in the tissue. This helps prevent edema. When albumin levels drop, more water leaves the blood and fluid builds up in the tissue, causing edema and potentially disrupting fluid balance in the blood as well. Hope that helps!
You're an amazing instructor! Explained the concepts easily, enthusiastically, but also added important caveats that really solidify my understanding! Thank you
thank you so much for this!! you just saved millions of my neurons from dying 😭
Finally, someone who explained well and without riddles!!!!! Thank you!!!!
You are a FANTASTIC teacher :) (y). Keep the good work going on. The world needs people like you.
thankyou for your motherly touch to explaining physiology helps fantastically!
I just learned more about Starling's law of the capillaries from this video than from my lecture class. Thank you for putting the time into making this video!
I finally understood this concept. Thank you so much. *Cries tears of joy 😭*
🤣 Aaaaah, Anatomy and Physiology!
OMG you provided an amazing explanation for this topic, and I finally understand this concept clearly ! You deserve recognition for your teaching !
Brilliant ✨
You explained the pathway by smoothy way
I'm not a native speaker and although I usually don't have any trouble understanding what's being said, I sometimes have a hard time "feeling" the topic since the language just doesn't feel 100% natural. But your way of explaining things is somehow just perfect for me, you're so easy (and dare I say fun or is that weird because we're trying to learn something here? :p ) to listen to! This is perfect for me, thank you.
Thank you for letting me know! So glad this approach works for you :)
Wow this video was so helpful. Best explanation of oncotic/osmotic and hydrostatic pressure in relation to the capillaries I've seen so far. Thank you!
Thanks! So glad it was helpful :)
Thank you so much. It's clear for a non-native speaker as me. Somehow it helps perfectly on my understanding about the inflammation process in the pulp cavity. Thanks! from Viet Nam
OMG....LOVE THIS VIDEO SO MUCH REALLY HELPS...PRENURSING STUDENT WITH 3KIDS STUCK IN HOME DURING THIS PANDEMIC ..CAN CAUSE FOR EXTRA HELP..ALL ONLINE CLASSES SO THIS VIDEO REALLY HELPS.. SOMETIMES THESE CONCEPTS CAN BE TRICKY BUT HELPS WHEN U HAVE FULL KNOWLEDGE ..THANKS SO MUCH
I LOVE your videos and your apparent love of science is contagious!
the best explanation I've seen so far! Thanks!
Amazing teacher..
I finally understood those two pressures
ALL THANKS
:)
:) Thanks!
Thank you so so much! You're an incredible instructor! Best explanation of this concept that I have ever heard in all my many years of education
Thank you - clearest information I have found on this - so helpful
the best explanation on this topic so far! thank you so much!
You're a big saver thanks a lot for making this easier for me
Wow, you explain things wonderfully and I'm so happy I found this explanation!
Thanq so much
Now so many things make sense to me
This capillary xchange was a questn mark to me till now
Amazingly xplained
Thanq so much
very helpful. as a heart patient whose fluid levels are unbalanced by 3 gallons, this is very informative.
5:50 Girly, that's hilarious. Thank you so much!
You're a natural teacher
You are a great teacher!! thanks for taking your time to make this video
I really appreciate your video!!! I'm currently taking an online A&P course and there's no lecture time. This video really breaks everything down and I like that you mentioned oncotic pressure and instead of colloid solution it's technically molecular
Thank you for taking the time to share this!
Excellent explanation. Thank you for being a great teacher! :)
THANK YOU SO MUCH FOR THIS VIDEO!!!! you're so amazing and I'm so very grateful for your work. thank you!!!
A very good video, perfect explaining. thanks!
Perfect combo for me as a refresher. I needed easily understandable visual and clear audible explanation, which is exactly what you provided. Thanks!
This was such a great help! Thanks for clarifying my IB Biology doubts. I do have a question. It wasn't clear to me how exactly the lyphatic system keeps the interstitial hydrostatic pressure at about a 0.
The extra fluid which leaks into the interstitium due to hydrostatic forces is taken by the lymphatics therby preventing edema.
just loved your teaching💕
thanks , i needed this refreshment for nursing school.
Huge help! Thanks you for simplifying this.
Thank you so much! You're video turned out very helpful for understanding. And you explained quite easily and flawlessly!! :)
I LOVE HOW YOU TEACH
This is an excellent video.
Wow thanks! Explained it so perfectly in a short time too!
That was amazing and well done. I'm so happy I found this video.
You’re amazing 👏🏻👏🏻! I hope I have doctors like you in my collage 👍🏻
Wow this was so great! Thank you! Thank you! Thank your for sharing online!
Thank you Camille, it helped me a great deal.
The pandemic has been rough for me taking science classes. I'm so happy I found this because my professor's lectures are SSSSSOOOOOO boring!!!
Beautiful explanation!!
Great explanation. Very well done
My review list 4 different pressure. My understanding is glomerular blood hydrostatic pressure pushes fluid out of glomerulus while capsular hydrostatic pressure pushes fluid back into the glomerulus. What I don't quite get is the difference between blood colloid osmotic pressure and capsular colloid osmotic pressure. Does blood colloid prevent water from leaving while capsular colloid pushes water out? I hope you still respond to this post! Your explanations are very helpful! Thanks!
+Brittany Jaramillo In the video above, we're discussing pressures in capillaries in general. The glomerulus is a modified capillary, and of course there are some special circumstances there that don't necessarily apply to other capillaries in the body :). To answer your question, the colloid pressure exerted by the blood "holds" water in the capillary (more protein staying in the blood will draw water into the glomerulus), while capsular colloid pressure will draw water out of the glomerulus and into the capsule. Hope that helps!
Thank you that is very helpful.. I am watching you from iraq 😍😍
Such a great explanation, thank you!
This video saved my life!! thank you so much you did an awesome job! keep up the great work!!!!!! also you have a lovely voice unlike my teacher who is so monotone and boring.
Glad you enjoyed it!
Delightfully helpful. Thanks so much!
Wow - just wow! Please do not take this the wrong way...please. I have hardly ever heard anyone, let alone a woman, explain something in such a concise and informative way without coming across a litlle full of themselves. Half-way through I subscribed! What a pleasure to have found your channel - it's 11:45 and I need sleep... but I will be back!!!
This was so well explained! Thank you!
Is the osmotic pressure drawn in the diagram that of the interstitial fluid? You mentioned the osmotic pressure being a counter pressure to the direction of water moving towards a higher concentration of solutes ie. Blood components in this video example
Physiology test on Friday..thank you very much!
Thank you for the excellent presentation, I wonder ,however, about the kinds of physiological changes that would occur at within such a space if a lateral force of negative pressure were applied over these tissues from the outside as happens during dry cupping..some estimate that a negative vacuum between -150 and 450mmhg may be created...I will be most grateful if you consider my request for an explanation
Hi, I'm currently doing pre-med and in my summarised notes, it's stated that fluid is drawn out at the interstitial fluid colloid osmotic pressure at 5mmHg, is this referring to the terms you use of fluid coming in because of the low hydrostatic pressure at the venous ends? Could you please clarify, thank you! Enjoyed your video!
Thank you. Very helpful video
Very well explained. Great job!
Thanks, Doug!
Thank you! That was excellent
Thank you! I really appreciate your work :)
super clear and well explained. Thank you!
Thank you! Very helpful.
you're amazing! thank you so much!
Omg..i m in love with ur concepts.. God bless you..
thank you so much!!!
Hooly mackerel, thanks so much!
Hey, great video! Finally understood how the capillary microcirculation works. Just one doubt though: interstitial colloid pressure tends to bring fluids from the capillary toward the interstitium while interstitial hydrostatic pressure bring fluids inside the lymphatic system?
Thank you in advance :)
I have a question. I have read that a high salt diet should not affect lymphedema, because lymphedema is not due to osmotic pressure, but rather oncotic pressure. Is this true? Can you explain this? Thank you.
Thank u
Awesome explanation!
☺☺☺
Thank u so much fr help...plz do guide me why does the osmotic pressure not change with the change in hydrostatic pressure?
Excellent. thank you very much
Thank you so much.
You are the best...Thank u
this is amazing, thank you so much!!
Thank you for this. Can you do video with starlings principle updated to show that in fact it's a net filration out of the capillaries and not reabsorption? Compare and contrast? Thank you!
This was so helpful, thank you
Thank you soooo much!
Thank you ma'am it helped a lot😊🙏
Ah I still don't get what oncotic pressure is - everywhere it is mentioned that it is the pressure exerted to PREVENT any more water absorption - what does that mean exactly, what exerts that pressure? It implies the two different solutions must already attain some sort of equilibrium just like in that sugar water example. Thank you!
thank you it helped me so much
You're welcome!
can the diameter of a capillary change ? or are there various sizes of the diameter of capillaries ? naturally vessels expand and contract , are rbc's single file at any point in capillaries concerning volume of serem in comparison to serem in for example the venous cavious? how condensed are rbc's in the left atrium or left ventricle?
Excellent!!!
Great video! We learnt about this in class. I wasn't sure what was the exact reason as to why the hydrostatic pressure of the interstitial fluid remains 0. We learnt that the interstitial fluid can be slightly negative or 0. Could you please tell me why?
awesome vid. so since RBCs, WBCs and plasma proteins can't leak thru, is it fair to assume something like a histamine or prostaglandin is going to affect the oncotic pressure since prostaglandins/histamines increase cell wall permeability, thus allowing the bigger molecules to leak thru, and therefore increasing oncotic pressure?
+oopalonga Yes, it depends on the local milieu, and generally anything that increases capillary permeability and promotes movement of WBC out of the vasculature and into the tissue will increase the interstitial oncotic pressure
Physiology for Hippies ok thanks!
I cannot understand the reason behind the relation between vasodilation and increased hydrostatic pressure. If hydrostatic pressure is the pressure opposed on the wall of the vessel, vasodilation should in fact decrease hydr. pressure not vice versa. Or is the dilation always accompanied with relatively more flow (diameter/flow relativity)? Robins says "Vasodilation increases flow thus increasing hydrostatic pressure".
Hi . You've done a great job . But could you explain me what is the role of Albumins in this case . I'm learning that they prevent edema but how this happens . Thank you :)
+Altin Izairi Albumins are produced in the liver and are the most abundant protein found in the blood. Because they are quite large, they cannot easily cross the capillary membrane. By staying behind in the blood they draw water towards them (oncotic pressure) and keep fluid in the blood rather than in the tissue. This helps prevent edema. When albumin levels drop, more water leaves the blood and fluid builds up in the tissue, causing edema and potentially disrupting fluid balance in the blood as well. Hope that helps!
Thank you doctor soo helpful
Great explanation
god bless this video helped me so much
amazing
Thanks a million!
Super I am a Tamil girl u teaching very well
you are amazing!
why are the plasma volume less than interstial volume if soloutes and water can move freely through them.
Thank you soooo much
Thank you so much for the video...very helpful💖🙏
Thank you! great share
good job dearie
Your amazing. Thank you