Ester vs Amide Local Anesthetics || How they differ?
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- เผยแพร่เมื่อ 15 ก.ค. 2024
- Amide local anesthetics play better therapeutic profile over ester local anesthetics in many aspects but still they can produce more toxic reactions than ester derivatives. In this video, the main differences between these two categories were discussed in detail.
#localanesthetics
#lidocaine
#benzocaine
0:00 Introduction
0:08 Groups in Local anesthetics
0:49 Types of local anesthetics
1:14 Ester and Amide LA
2:38 Differences
2:57 Acid dissociation constant (pka)
6:52 Onset of action
9:47 Chemical stability
13:07 4. Hypersensitivity
13:46 Drug interactions
15:08 Tissue toxicity
16:29 Ester LA
As a surgeon looking for quick refresher of info. I found your video illustration one of the best videos . Right to the basic points which are very important and use of animation. Well done
Glad you liked it ! Thanks for watching.
Thank you very much for this excellent and wonderful explanation. I wish you success
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We can differentiate them by how they are spelt, amides have 2 i’s while esters have single i
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Great video! Very in depth, and you explained concepts i knew before but forgot, good job!
Glad you enjoyed it! Thanks for watching.
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Thank you so much for this video, very helpful. It really helped me during my college exam season.
Glad it helped you. Thanks for watching.
Very clear understanding sir..💐
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Tnq very much sir for giving valuable information sir . Finally your explanation so good sir
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Excellently described 👌🏻 Loved it😍
Glad you liked it. Thank you
Thank you for your video! Sir just one thing, for onset of action, it is not pKa , but concentration what matters, ester have faster onset than amids, beacuse they are less toxic , they can be given in higher concentrations, 3% chlorprocaineis the fastest, even it has highest pKa
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Thank you sir
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Sir why are you keep saying anastics again and again?? Isn't it anesthetics?? I don't want to sound mean, just couldn't help myself from asking ..
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