Inheritance: Autosomal Linkage | A-level Biology | OCR, AQA, Edexcel

แชร์
ฝัง
  • เผยแพร่เมื่อ 27 ธ.ค. 2024

ความคิดเห็น • 47

  • @vel3947
    @vel3947 3 ปีที่แล้ว +45

    this video made me question everything i've learned about chromosomes until i looked at the comments
    this is why youtube never should've removed dislikes-

  • @amirrezafahimi6579
    @amirrezafahimi6579 2 ปีที่แล้ว +9

    I was terribly confused until I read the comments and I understood the problem with this video. Thanks for sharing your knowledge for free, but please consider refining this video.

  • @kfr9892
    @kfr9892 3 ปีที่แล้ว +26

    4:56 The blue chromosome shouldn't have both G and g because the sister chromatids should be genetically identical with the same alleles.
    Instead the blue should have G and R on both chromatids and the yellow should have g and r on its chromatids.
    At 6:20, therefore, it should have GG at the top and RR at the bottom.

  • @bellagriffiths7751
    @bellagriffiths7751 3 ปีที่แล้ว +33

    Unfortunately there are mistakes in this video which need correcting. All alleles on sister chromatids are identical as they are copied during DNA replication before meiosis occurs (mistakes can occur during this process leading to mutations but so rare its not worth mentioning here). What is shown in the video are not homologous chromosomes but sister chromatids of one chromosome so the alleles should be the same. He should have drawn two blue chromosomes(a homologous pair) one with G on each sister chromatid and the other with g on each of the sister chromatids. Similarly he should have drawn two yellow homologous chromosomes one with RR and the other with rr.

    • @bellagriffiths7751
      @bellagriffiths7751 3 ปีที่แล้ว +2

      He also worked out the gametes at 09:30 wrong. Because the genes are linked you can only get GN or gn gametes. You can get gametes that are Gn or gN if crossing over happens between homologous chromosomes. This would haowever be rare so there would only be very few if any offspring showing these new recombinant types.

    • @justsomeguywholikesramen
      @justsomeguywholikesramen 2 ปีที่แล้ว +3

      @@bellagriffiths7751 thanks, I was actually getting really confused at that part.

    • @jcn268
      @jcn268 ปีที่แล้ว +1

      i think he was calculating F2 generation

  • @mjp34
    @mjp34 5 ปีที่แล้ว +28

    You seem to be representing homologous pairs of chromosomes as sister chromatids (at5:08). Surely the blue and yellow chromosomes are the homologous pair whilst the individual blue and yellow are sister chromatids joined via the red dot/centromere (and hence the alleles should be the same)?

    • @aaronmills6103
      @aaronmills6103 4 ปีที่แล้ว +6

      You're right. I'm afraid they've made a mistake in the video.

    • @SuperStargazer666
      @SuperStargazer666 2 ปีที่แล้ว

      Sooooo confusing. It looks like a single chromosome with two chromatically!!!

  • @amranmohamed5125
    @amranmohamed5125 4 ปีที่แล้ว +25

    Why didn't you use all of the gametes for the punnet square? ended up having a 4x4 square- isn't it a dihybrid cross because there are two characteristics that are linked?

    • @kalifirscha9171
      @kalifirscha9171 3 ปีที่แล้ว +3

      I think because GN are autosomally linked, so they tend to be inherited together vs. Gn or gN.

  • @cluckoothechicken5721
    @cluckoothechicken5721 4 ปีที่แล้ว +31

    9:33 can someone explain why in the next punnett square, he only uses GN and gn for both? What if the dominant G allele occured with the n allele on the same chromosome? Doesn't that lead to Gn and consequently gN?

    • @cluckoothechicken5721
      @cluckoothechicken5721 4 ปีที่แล้ว +8

      I asked my biology teacher about this and in fact, it could be Gn and gN autosomally linked. However, in the textbooks and most examples only use homozygous genotype parents i.e. GGNN and ggnn with gametes GN and gn respectively.

    • @Ururowndoc
      @Ururowndoc 2 ปีที่แล้ว +1

      Exactly!!! I am a biology tutor. He skipped that part. That’s the case for non-linked cases. As this is assumed to be linked trait, the Grey Colour and normal wings are on the same chromosome so will always be inherited together. Therefore it’s 2 gametes.

  • @0rjrorbrkrn3349
    @0rjrorbrkrn3349 5 ปีที่แล้ว +17

    At 9:48, why did you use only use those 2 combinations as the gametes in parents. If I wrote gN and Gn instead, it would change the phenotypic ratios. How would i know which combination to use?

    • @Sara-vs1ww
      @Sara-vs1ww 5 ปีที่แล้ว +4

      I did the same as you Donna. also how would we know to use a 2 by 2 punnet square and not a a 4 by 4 punnet square?

    • @0rjrorbrkrn3349
      @0rjrorbrkrn3349 5 ปีที่แล้ว +1

      @@Sara-vs1ww u would use the 4 by 4 square if they arent linked because the gametes would then have 4 different combinations. if they are linked then it would be a 2 by 2 punnet square

  • @hanamostafa5268
    @hanamostafa5268 4 ปีที่แล้ว +8

    4:56 how can u say that both of them are homologous chromosomes? and genes are different in the same loci like how ever could R r in a chromosome will be in the same loci as G and g .This is not a definition of homologous pairs they should be carrying the same genes but different alleles as one from father and mother. Or they are just 2 different chromosomes not homologous???

    • @Yhh272
      @Yhh272 4 ปีที่แล้ว +2

      The blue chromosomes is a homologous pair and the yellow chromosomes is the other homologous pair....i think

    • @anonymousmc5064
      @anonymousmc5064 4 ปีที่แล้ว +4

      This is incorrect. They're both homologous chromosomes, which will indicate that they have the same loci. Thus placing both shape and colour at the same loci on the maternal and paternal chromosomes is a mistake in the video. You are in fact correct to point this out.

    • @davidmkwizu76
      @davidmkwizu76 4 ปีที่แล้ว +1

      But the homologous pairs aren’t identical I swear.

    • @anonymousmc5064
      @anonymousmc5064 4 ปีที่แล้ว +2

      @@davidmkwizu76 They have the same gene loci. However, can have different alleles. So no they're not.

    • @sam-rx1tj
      @sam-rx1tj 4 ปีที่แล้ว

      This is only gonna confuse you. Don't follow the diagram. Follow them from the book.

  • @Ururowndoc
    @Ururowndoc 2 ปีที่แล้ว +5

    Hi, good video but bit confusing at 9.44, I think you skipped the part where it’s autosomal linkage. There are 4 different gametes which would be the case in a non-linked inheritance. And here we are showing 2 because it’s linked.

  • @areeshahaider7937
    @areeshahaider7937 4 ปีที่แล้ว +2

    I dont understand at 8:50 u say that they can not be bred cuz they are hetrozygous cam someone plz explain why??

    • @negheg9270
      @negheg9270 4 ปีที่แล้ว +1

      He isn't saying that they can't be bred together, when he puts the cross there he means that they *are* being bred.

    • @areeshahaider7937
      @areeshahaider7937 4 ปีที่แล้ว

      @@negheg9270 thanks

  • @yusurkassem4174
    @yusurkassem4174 3 ปีที่แล้ว +1

    you did not explain how to choose which genotype goes in the punnet square as we don't know which two characteristics are autosomally linked.. it could be Gn and gN that are autosomally linked how am i supposed to know which two to put in the punnet square

  • @joyliam5371
    @joyliam5371 3 ปีที่แล้ว +5

    The main problem in this video is that he should include brackets when writing out the genotypes of the flies, which is (GN)(gn). This will result in getting parental gametes which are GN and gn only. If you don't include brackets, you will get GgNn which is like a normal dihybrid cross.. When we are talking about autosomal linkage, it is like compulsory to include brackets cuz it is not like a normal dihybrid cross.
    And if you're using gametes which are GN and gn, you will get offsprings which have genotypes of (GN)(GN), (GN)(gn), (GN)(gn) and also (gn)(gn). The ratio is the same as the ratio in the video but the method of deriving the gametes is inappropriate. Could have explained it in a clearer way to avoid misunderstanding.. Need to include brackets as well. You can refer A Level Biology Textbook which also includes brackets...

  • @inanutshell5204
    @inanutshell5204 2 ปีที่แล้ว +1

    I don't understand how he gets from having 4 parent gametes in step 2 (GN) (Gn) (gN) (gn) to just 2 gametes in step 3 (GN) to (gn)

  • @tazneentani536
    @tazneentani536 3 ปีที่แล้ว +3

    Thank you for this

  • @yusurkassem4174
    @yusurkassem4174 3 ปีที่แล้ว +8

    this video just confused me more great

    • @thomasowen1855
      @thomasowen1855 3 ปีที่แล้ว +2

      there are lots of mistakes in this video

  • @Thepinkhoodiegirl
    @Thepinkhoodiegirl 2 ปีที่แล้ว +1

    i wish you were my class teacher :(

  • @BagelBoi4000
    @BagelBoi4000 2 ปีที่แล้ว

    This is why youtube shouldnt have removed dislikes, first video that comes up when you search for this and it is wrong apparently... nice

  • @FahadAli-uv2ew
    @FahadAli-uv2ew 2 ปีที่แล้ว

    good

  • @buddhikaariyaratne504
    @buddhikaariyaratne504 11 หลายเดือนก่อน

    This video is terrible. Explanation all wrong. Homologous chromosomes should have alleles for the same gene. Not different genes as shown. Sister chromatids joint by centromere should have exactly the same alleles.

  • @vari1535
    @vari1535 5 ปีที่แล้ว +5

    Yesss finally I get it

  • @ayesha905
    @ayesha905 5 ปีที่แล้ว +2

    Thank youuu ❤️

  • @matthewbirchenough2930
    @matthewbirchenough2930 3 ปีที่แล้ว +1

    Bruh your video is wrong

  • @mahsak7247
    @mahsak7247 3 หลายเดือนก่อน

    Total waste of time:)

  • @notsnape9414
    @notsnape9414 2 ปีที่แล้ว

    This is a very bad video. Why would you confuse people like that