What is Sarcopenia? Definitions, Diagnosis and Developing Interventions - Christy Carter
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- เผยแพร่เมื่อ 28 ก.ย. 2024
- Rejuvenation Biotechnology 2014
Musculoskeletal Disease Session (August 23, 2014, 12:30pm)
"What is Sarcopenia? Definitions, Diagnosis and Developing Interventions"
Presenter: Christy Carter, Assistant Professor, Department of Aging and Geriatric Research, Institute on Aging, University of Florida.
Dr. Carter received her PhD in Experimental and Biological Psychology from the University of North Carolina at Chapel Hill and her post-doctoral training at The Wake Forest University School of Medicine in Winston-Salem, North Carolina.
Globally , Dr. Carter’s current research interests lie in preserving physical function and healthspan during aging; and in particular focuses on the use of a preclinical rodent model of aging to test a variety of late-life interventions designed to mitigate sarcopenia. Furthermore, she has demonstrated that the application of standardized physical performance measures to a variety of animal models of aging may help to define similarities between species in the underlying mechanisms of sarcopenia, the age-related decline in performance, disability, and longevity. Indeed the assessment of behavioral outcomes is essential for measuring the efficacy of any late-life intervention in the context of mitigating declining performance and improving healthspan. She has extended this area of research to other special aging populations such as the frail and obese, and has developed combinatorial therapies, using these compounds in conjunction with behavioral modification such as exercise.
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great video about sarcopenia
I love the irony. You can administer exogenous agents such as testosterone and growth hormone and it will increase muscle mass, just not muscle strength.
Ha ha. There is no free lunch for subjects (patients) and no magic bullet for the medical establishment.
Looks like low carb diet, intermittent fasting, high-intensity interval training, and weight lifting are going to be the only things that really work in promoting optimal health, longevity and minimal physical decline as we age.
no magic bullet
Seems enough to answered for our need 5:53
sad, they don't know anything at all about a massive problem. strange. we know of far away galaxies but nothing about the muscles even with animal experiments. is the wrong people becoming biochemists? while the sharp work in cosmology?
FDA IS CRUEL!
THE FDA DOESN'T RECOGNIZE SARCOPENIA. DONN'T THEY HAVE EYES?
bob FDA is a load of overpaid useless assholes!
I’ve started walking faster since I watched this. It might not make me live longer, but I will have more time to rest.
19:10 rapomycin
Blocks mtor
20:09 longevity but not health span
20:52 rapomycin helps maintain muscle in older mice
Thank you
At 78 I am a fast walker (2 to 3 miles a day) but are having trouble keeping the rest of my body from wasting. What can I do?
Thanks for your video, John
zpoedog - Lift weights moderately, maintain a healthy diet, cut down the number of miles walked from two to one per day so as not to unnecessarily over-use your hip and knee joints, and get your hormone levels thoroughly checked by a competent professional. At your age it is highly likely that your GDF11, growth hormone, and testosterone levels are low. As a result, exercise alone will only get you so far. By returning those hormone levels to the levels of your 30-40 year old self, you will reap benefits you would think were only attainable in a sci-fi novel, but are actually available today. Start contacting anti-aging clinics that specialize in such treatments and take advantage of modern technology.
Some say increase protein intake (besides weight lifting).
@@SI-ln6tc You may be right. I am 83 now and have increased my plant based protein and feeling OK.
high protein diet, at least 2g pr kg lean body mass, resistance training hard and heavy enough to bring your muscles “to failure” repeatedly (eg 4x8 reps for an excercise, at least 12 different excercises, at least twice a week, increase weights until you cannot make the 9th repetition in a set, use dumbbells wherever you can to decrease training injury risks), Testosterone Replacement Therapy to fuel your resistance training, 5-10 gram of creatine a day, take melatonine before bedtime to sleep more, buy a cheap sleep tracker like fitbit inspire 2 to track and optimize your sleep, as well as track your vo2-max.
My dad is 74, I am taking him to the gym and I am teaching him to lift.
TH-camrs to follow to learn to lift:
Jeff Nippard
Musclemonsters
athleanx
jeremy ethier
If you have insulin resistance in any degree: dump carbs, substitute with protein, or fat, and take Berberine 3x a day.
if you can’t get TRT, or if you want to top it off, take DHEA, a testosterone precursor. Testosterone will enable your strength gains, if you train as hard as you can.
Take your time in the gym, you don’t need to pace yourself between sets, only when you are doing your set.
Don’t substitute weight for more repetitions. Only the repetitions just before the repetition that fails or would have failed gives you any gains, and only if you would have failed before the 12th repetition. Training with weights where you can push yourself to 15 or 20 repetitions will not yield you strength gains, only fatigue (and a bit of cardio).
Suggested excercises:
Incline bench press, dumbbells, 30 degree angle
Squats with dumbbells hanging down your sides
Bicep curls with dombbells
Farmer’s Walk with dumbbells
Crunch with cable (abdominal excercise)
Romanian deadlift with dumbbells. Carefully, you need right technique.
Arnold Press w. dumbbells (shoulder excercise)
Face pulls w. cable or dumbbells (in which case it is face down on your incline bench)
Side lateral raise
Tricep pushdown w. cable & bar
Du,bbell row face down on the incline bench
If you want to dive into the rabbit hole of biohacking, the youtubers Lance Hitchings and Brad Stanfield are good.