VALIDATION OF PURIFIED WATER SYSTEM

This video explains about the quality and regulatory requirements of purified water system. this video give guidance for doing performance qualification of purified water generation, storage and distribution system.

[@anand-spiritualquotent5292]

Very good video.. Lot's of learning.. Thanks

[@pothalasiva1041]

Good explanation sir.. thank you sharing Sir..

[@kunalmistry5856]

Thank you so much sir for designing such a informative video, it's very useful

[@prakashpatil846]

Nice presentation in short

[@k50159]

Thanks so much

[@titonsaha799]

Wow, it's really great!

[@tanujsharma4207]

Such a needfull video thankuh Sir

[@minathsolankar]

Thank you very nice information

[@bharatbhushansaini2673]

Good knowlegble vedio sir

[@yogeshdoke2483]

nice to understand

[@arunkashyap8301]

Good work sir

[@amitkumarshukla3234]

Nice presentation

[@arundeep4124]

Good work sir.. it can be more detailed

[@bhagyalaravikumar7166]

Nice sir but in some time u r explanation not clear other wise nice information and very good information and knowledge.

[@easyqualitylearning6790]

If any thing is not clear please let me know I will try to make it clear.

[@mansouralajeemi9101]

THANK YOU SO MUCH

[@shokenderkumar2738]

Sir thankbu so .much

[@AyurPuran]

Dear in phase 2 we can not use water for manufacturing , we can use for only washing purpose ..... revert pls am I right or not ?

[@easyqualitylearning6790]

Yes in phase II we can use water for manufacturing as well as washing

[@AyurPuran]

@@easyqualitylearning6790 ok thanks

[@CreativeCorner25]

Sir plz make video on latest WHO and USP guidelines for purified water and system.. parameters online offline linits..like toc conductivity. Frequency of replacement.. flow rate, pressure, temperature,

[@vaibhavshetkar3797]

How to make specifications for soft water, ro 1, ro 2, edi while doing performance qualification??

[@mohitkumar-hh2vy]

Vegod sir

[@mohdbaseem46]

sir we are going to extend our user point of wfi as well as the loop line system , So I was asking that the revalidation activity will start from Phase-1 or Phase 2 ???
Please give the answer of my question 🙏🏼

[@easyqualitylearning6790]

First you need to do requalification of physical parameters and once it is ok then it will start from phase I. Risk assessment is must in this.

[@angeliei]

Thank you sir
What if a pharmaceutical industry has stopped working for a period of time? a revalidation of the PW system must be done?

[@easyqualitylearning6790]

Stoppage need to be evaluated, if all utilities are also stopped including recirculation pump of water system then sanitisation of system and concurrent validation can be done. It will also depend on the shut down duration. Risk assessment will help in this.

[@easyqualitylearning6790]

If recirculation pump is on then revalidation may not be required, but pump is also closed then concurrent validation can be considered.

[@angeliei]

It relies on recirculation pump, then.
Thank you sir.
Please, make a video on risk assesment in pharma if you can

[@easyqualitylearning6790]

@@angeliei I will try may be after some time

[@easyqualitylearning6790]

If content is useful then share with others also

[@Vishalchaurasiabpharm]

what document required for replace electro deionizer system in purified water system

[@easyqualitylearning6790]

Mr. Vishal, I hope you are talking about the EDI unit replacement as a part of breakdown. You need to do the risk assessment of the water system after change in which you will need technical specs. Of old and new EDI module. If the make and model as well technical specs.are same then it reduces your task if it is different it will trigger requalification of the system.

[@Vishalchaurasiabpharm]

If technical spec of EDI unit is same, then risk assessment is sufficient or any other documents required for EDI replace.

[@easyqualitylearning6790]

In risk assessment evaluate risk and probably you may have to do analysis of out put after EDI and results need to be compared with earlier results.