Deadly Strychnine - Periodic Table of Videos

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  • เผยแพร่เมื่อ 16 มิ.ย. 2024
  • Discussing Strychnine, a famous poison and an "Everest" of synthetic chemistry.
    Featuring Rob Stockman and Martyn Poliakoff.
    Very Fast Death Factor: • Very Fast Death Factor...
    Frog Poison: • Frog Poison - Periodic...
    Calcium ions are 2+
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    From the School of Chemistry at The University of Nottingham: bit.ly/NottChem
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  • วิทยาศาสตร์และเทคโนโลยี

ความคิดเห็น • 629

  • @mrraimundo130
    @mrraimundo130 8 ปีที่แล้ว +450

    The 2nd part of the video when he explains the progression and achievements of organic chemistry is awesome.

    • @jasondoe2596
      @jasondoe2596 8 ปีที่แล้ว +7

      Agreed!

    • @ArgoIo
      @ArgoIo 8 ปีที่แล้ว +20

      +Szilágyi Szabolcs My jaw dropped several times at that part. First, a 28 step synthesis is absolutely insane to carry out and second, managing to increase the yield of a synthesis by a factor of 100 000 is nothing else than amazing!

    • @Freakschwimmer
      @Freakschwimmer 8 ปีที่แล้ว +5

      +Szilágyi Szabolcs
      Oh yes it absolutly was, +Periodic Videos, we need more on this topic!!

    • @Freakschwimmer
      @Freakschwimmer 8 ปีที่แล้ว +6

      evilcam I agree 140% !

    • @_ninthRing_
      @_ninthRing_ 3 ปีที่แล้ว +2

      This is really fascinating to me. I'd be really curious to know how many steps (& what yield) that the actual plant needs to do this & how each one evolved.
      I'd also like to know if any insects, or larger organisms, have managed to adapt to process the toxic stuff, enabling their consumption of the plant.

  • @dangerouslytalented
    @dangerouslytalented 8 ปีที่แล้ว +853

    True chemistry geek: You can tell what something tastes like by looking at the molecule.

    • @slendy9600
      @slendy9600 8 ปีที่แล้ว +15

      what i want to know is how they found that out... they mustve at some point gotten a bunch to sample poisonous materials and make a note of their flavour beforr being overcome by symptons xD

    • @tyler111762
      @tyler111762 8 ปีที่แล้ว +12

      +slendy9600 i would imagine you can see how the molecule can show you what parts of the tongue will register it? maybe?

    • @Scy
      @Scy 8 ปีที่แล้ว +28

      +tyler111762 He says in the video what triggers it. Every molecule with this particular node, edge or corner will taste this way.

    • @SeaUrchinZone
      @SeaUrchinZone 8 ปีที่แล้ว +41

      +dangerouslytalented to extend it further: Hydroxyl groups often taste sweet, acidic compunds taste sour and alkaline stuff mostly tastes kinda soapy. Salts (ionic compounds) taste, well, salty, and glutamates (MSG for example) taste hearty/umami.

    • @dangerouslytalented
      @dangerouslytalented 8 ปีที่แล้ว +7

      Undead Gaddafi
      NNEEEEEUUUURRRRRRDDD@!!!!!!!!!!!!

  • @paolomarcelli7071
    @paolomarcelli7071 7 ปีที่แล้ว +185

    "What happened to the professor?"
    "I'm the professor"

    • @beautruex7012
      @beautruex7012 4 ปีที่แล้ว +1

      Hilarious!

    • @WillKrause21
      @WillKrause21 3 ปีที่แล้ว +6

      "I'll tell you after you finish your tea"

  • @rkrokberg
    @rkrokberg 8 ปีที่แล้ว +28

    As someone who plans on taking a PhD in organic chemistry, this video pleased me greatly.

    • @Adsman100
      @Adsman100 ปีที่แล้ว

      100% agree 7 years on

  • @pinkdispatcher
    @pinkdispatcher 8 ปีที่แล้ว +46

    If the decimal points are all correct, Macmillan's is actually 100,000 times more efficient than the original process, not just 10,000.

  • @BarragePker6
    @BarragePker6 8 ปีที่แล้ว +9

    I want more of these! As an organic chemistry student I think this is fascinating.

  • @TrilobiteTerror
    @TrilobiteTerror 8 ปีที่แล้ว +50

    I collect antique bottles (primarily antique poison and medicine bottles). One of my favorites is a "Fraser's Tablet Company Chocolate coated Iron, Arsenic, and Strychnine" medicine bottle from the late 1800's.

    • @TrilobiteTerror
      @TrilobiteTerror 8 ปีที่แล้ว +3

      +MrRandysh Lol, I just Google searched the bottle (to see if I could find anything else on it) and I found a "Worthpoint" webpage on the same exact bottle I bought. Apparently there aren't very many around.

    • @gorillaau
      @gorillaau 4 ปีที่แล้ว +4

      What ailments was it supposed to cure?

    • @dsandoval9396
      @dsandoval9396 4 ปีที่แล้ว

      Very cool.

    • @gorillaau
      @gorillaau 4 ปีที่แล้ว

      @@africanelectron751 Excellent, make mine a double!

    • @gorillaau
      @gorillaau 4 ปีที่แล้ว

      @James Sloan Obviously the sales guy spruiking the stuff wasn't converted!

  • @JP-wx6uh
    @JP-wx6uh 6 ปีที่แล้ว +13

    More toxicology-based chem videos please! This is great

  • @zacbachmeyer6330
    @zacbachmeyer6330 8 ปีที่แล้ว +3

    i just wanted to say that after discovering this youtube channel i was, for several days, rendered incapable of accomplishing anything other than feverishly starting the next video as quickly as the last one ended. you fine folk have created a wonderful resource for advancing public interest in one of the most (if not the absolute) important scientific fields, and in a way that engages audiences and is understandable as well as enjoyable for anyone from a student in prmary school, to a seasoned researcher. a big thank you to the periodic videos team. please keep releasing new material as long as physically possible, and beyond.

  • @TheButtDepot
    @TheButtDepot 4 ปีที่แล้ว +10

    "Although we have made a few natural products over the years which were really quite potent"
    Lit, my guy.

  • @nokomarie1963
    @nokomarie1963 8 ปีที่แล้ว +15

    In the old pharmacy I worked at in my youth they had little narrow tubes full of little stacks of seven small white tablets. They were strychnine tablets sold way back when to poison mice. We had lots of interesting leftovers like that tucked away in the back rooms.

    • @OF01975
      @OF01975 5 ปีที่แล้ว

      I bet u took 4 thinking they were opiods

  • @theslimeylimey
    @theslimeylimey 8 ปีที่แล้ว +107

    I'd like to see a video about Ferric ferrocyanide

    • @ryan22370
      @ryan22370 8 ปีที่แล้ว +5

      +theslimeylimey Me too. We have some in the lab and don’t know much about it.

    • @SpektralJo
      @SpektralJo 8 ปีที่แล้ว +9

      +ryan22370 It is used for example as an antidote for Thallium and radioactive Ceasium poisoning :)

    • @elvida17
      @elvida17 8 ปีที่แล้ว +4

      +theslimeylimey it's used as an intense green blue pigment (I have some in my paint kit) often called prussian blue or iron blue :)
      As somebody else mentioned it can also be used a treatment for radioactive poisoning and heavy metal poisoning and is considered an important medicine.
      I'd be great if the professor was to do a video on it

    • @LHommeDeCave
      @LHommeDeCave 8 ปีที่แล้ว +17

      Id rather see a video about Azadoazide Azide

    • @ambrosefogarty6423
      @ambrosefogarty6423 8 ปีที่แล้ว +1

      +LHommeDeCave
      :0 you want to see something explode

  • @ehfoiwehfowjedioheoih4829
    @ehfoiwehfowjedioheoih4829 8 ปีที่แล้ว +3

    Thank you for making these great videos

  • @jkpp.
    @jkpp. 8 ปีที่แล้ว

    Fantastic video! Arguably one of the best PT videos.

  • @techstate2863
    @techstate2863 8 ปีที่แล้ว +1

    what a great teacher! his passion is obvious. thanks for making the vid.

  • @8bitboxing
    @8bitboxing 8 ปีที่แล้ว

    love the videos you guys upload. please don't stop!

  • @Bourinos02
    @Bourinos02 8 ปีที่แล้ว +6

    Very interesting! Always nice to see that organic chemists are still making breakthrough in synthetic chemistry!
    Greetings from Strasbourg University!

  • @Friday9951
    @Friday9951 8 ปีที่แล้ว +31

    "My PhD students over the years...have made a few rather potent products..." There's another video right there! :-D

  • @MephLeo
    @MephLeo 8 ปีที่แล้ว +123

    A chemist that wanted to poison his wife... I suspect that marrying a chemist is one of the most dangerous things one can ever do.

    • @Isolanporzellator
      @Isolanporzellator 8 ปีที่แล้ว +56

      +Leopoldo Aranha Probably less risky than marriying a chemists wife^^.

    • @Metalhammer1993
      @Metalhammer1993 8 ปีที่แล้ว +5

      +Leopoldo Aranha well yeah. marrying a former chemistry student (a failed one) is deadly enough. seriously my first three semesters i learned nothing but what kills you how^^ (well i learned a lot more but i learned a lot about toxic substances)

    • @wowo316g5
      @wowo316g5 3 ปีที่แล้ว

      Sus

    • @santaclauseking
      @santaclauseking 2 ปีที่แล้ว +2

      Well if you've seen breaking bad...

  • @moosehead4497
    @moosehead4497 8 ปีที่แล้ว +1

    Great Video! I really enjoyed the end about total synthesis, great for someone pursuing Ochem.

  • @natjimoEU
    @natjimoEU 8 ปีที่แล้ว

    this video is awesome !!
    You should do more of these.

  • @TreeceTalk
    @TreeceTalk 8 ปีที่แล้ว

    Liked it all, really enjoyed the part detailing the history of improvements in the synthesis process. Thumbs up :)

  • @pepperco100
    @pepperco100 3 ปีที่แล้ว +4

    Strychnine was an important and effective heart medicine even in the 20th century. When we cleaned out my late grandparents' old house, a box of my grandfather's strychnine pills from 1930s was found. If my memory is correct, each pill contained 1/30th of a grain of strychnine.

    • @WinterReflections
      @WinterReflections 2 ปีที่แล้ว

      Is "a grain" an accurate unit of measurement? It should be milligrams or micrograms. But I know medicine has changed (improved) a lot.

    • @vfeeh
      @vfeeh ปีที่แล้ว

      @@WinterReflections yes, it was an accurate measurement back in the day. One english grain is equivalent to 65 mg

  • @taofledermaus
    @taofledermaus 8 ปีที่แล้ว +194

    Has anyone done a study about the stereotype that professors are typically, absent-minded?

    • @joshuarichardson6529
      @joshuarichardson6529 8 ปีที่แล้ว +68

      But who would do the study, if not the very absent-minded professors themselves? Maybe the lack of such a study is the proof it's true.

    • @taofledermaus
      @taofledermaus 8 ปีที่แล้ว +54

      Huh? What were we talking about?

    • @Icathiann
      @Icathiann 8 ปีที่แล้ว +6

      +TAOFLEDERMAUS Wtf jeff you're like in every channel I go.

    • @TonboIV
      @TonboIV 8 ปีที่แล้ว +8

      +TAOFLEDERMAUS The professor of strange ballistics.

    • @steveo21882
      @steveo21882 8 ปีที่แล้ว +1

      man you are everywhere

  • @Whalebone471
    @Whalebone471 4 ปีที่แล้ว

    Love this ,brilliantly explained.

  • @GuerrilhaBox
    @GuerrilhaBox 8 ปีที่แล้ว

    i'm so glad for your existence it makes my life a lot less boring i love your videos keep sharing your knowledge i will be watching :)

  • @dougjordan3775
    @dougjordan3775 8 ปีที่แล้ว

    Brilliant, thanks for the excellent explanation.

  • @jacobs83133
    @jacobs83133 ปีที่แล้ว +1

    Loving everything about chemistry and technology.Cheers 😊

  • @NicklasRyding
    @NicklasRyding 8 ปีที่แล้ว +1

    Thanks for a new video :) Really interesting.

  • @RevakOnPC
    @RevakOnPC 8 ปีที่แล้ว +2

    I'm having withdrawals from so few videos lately, I've watched every one on the playlist multiple times and many on the related channels as well.
    Love you guys, don't ever stop!

  • @AlChemicalLife
    @AlChemicalLife 8 ปีที่แล้ว +3

    Can we get more videos with Rob in them ? I really enjoy the videos he is in !

  • @OwenPrescott
    @OwenPrescott 8 ปีที่แล้ว +144

    "Allthough we have made a few... natural products over the years *cough*... which, er which are really quiete potent".

    • @lorenzo42p
      @lorenzo42p 5 ปีที่แล้ว +8

      haha, best part of the video. that made me laugh

    • @zorro456
      @zorro456 5 ปีที่แล้ว +5

      @@lorenzo42p Tastes like....Heroin.

    • @grendelum
      @grendelum 4 ปีที่แล้ว +1

      It was phenethylamines.

  • @kowalityjesus
    @kowalityjesus 8 ปีที่แล้ว

    very cool story about the synthesis, I'm so lucky to know about this youtube channel!

  • @killswitch4984
    @killswitch4984 4 ปีที่แล้ว

    Love your stories!!!!

  • @bcat010
    @bcat010 8 ปีที่แล้ว +36

    Have they done a video on ATP? As a former Biology student, I would find a detailed description of ATP quite interesting.

    • @iliakorvigo7341
      @iliakorvigo7341 5 ปีที่แล้ว +15

      I would think a former biology student wouldn't need a detailed description of ATP.

    • @tylerpeterson4726
      @tylerpeterson4726 4 ปีที่แล้ว +7

      @@iliakorvigo7341 The chemistry of ATP is frequently abstracted away, not talking about the chemistry in depth like a chemist on Periodic Videos would

  • @Ravedaze.
    @Ravedaze. 8 ปีที่แล้ว

    Very interesting thanks for the information

  • @BrunoRegno
    @BrunoRegno 8 ปีที่แล้ว

    Very interesting video. I wish that, as a norm, when discussing poisons, information on detection and antidotes was available.

  • @AndrewWilsonStooshie
    @AndrewWilsonStooshie 8 ปีที่แล้ว +19

    Interesting. Didn't know much about strychnine.

  • @flaplaya
    @flaplaya 8 ปีที่แล้ว +1

    Absolutely amazing, the 1000 fold improvement on total synthesis in 55 years.. The attention to detail here on the chemical of the day has my vote as number one science channel on the web. Brilliance. Anyone feel like guessing the starting material? And no cheating! My first guess would be Tryptamine.

  • @uberskank1424
    @uberskank1424 8 ปีที่แล้ว +1

    like the way this guy explains things.. very interesting.

  • @thec00kiem0nst3r
    @thec00kiem0nst3r 8 ปีที่แล้ว

    Rob Stockman is a very clear speaker. Well done Sir!

  • @Jarastlad
    @Jarastlad 8 ปีที่แล้ว

    Very interesting video, especially the second part ! I was wondering though what were the uses of Strychnine, apart from the use as a pesticide ?

  • @brcooke1
    @brcooke1 8 ปีที่แล้ว

    That is a fantastic video. I am a neuroscientist, and I've never heard or read a more clear elucidation of chemistry than this one. - "In truth, it is just atoms and the void."

  • @DrGreenGiant
    @DrGreenGiant 5 ปีที่แล้ว

    You talk about it looking beautiful, which it is. I feel the same about cyclopropane and cyclobutane, any chance of a video on these two? Keep up the great work! Simon, RA @ Lboro Uni, Aero & Auto Eng

  • @Mrdresden
    @Mrdresden 8 ปีที่แล้ว

    Fantastic video. One thing I feel sometimes is missing though is any discussion about actual use cases in the modern world of the chemicals being discussed. For instance, the synthesis of the chemical was carried on in the '90s and into the modern day, but what was the incentive for doing that? Simply to refine a process that could be applied to other chemicals of a similar kind or is there a industrial application to be had from being able to make Strychnine on a 'mass' scale?

  • @gingganggoolie
    @gingganggoolie 8 ปีที่แล้ว +45

    organic chemistry, or as it is usually known, wizardry

  • @damian-795
    @damian-795 6 ปีที่แล้ว

    Wow great vid, thanks Bro x

  • @dannybejan2022
    @dannybejan2022 8 ปีที่แล้ว

    This is awesome! I want to hear more about the rock stars of organic chemistry

  • @n3r0z3r0
    @n3r0z3r0 8 ปีที่แล้ว

    Thanks for video! Could you please explain in more detail how the spectroscopy works and how you can detect complex molecule structure using by using it.
    Be a delightfully if this process will be shown and explained on the example.
    Thank you

  • @RedInferno112
    @RedInferno112 8 ปีที่แล้ว

    Been in the lab before! Awesome place, I just need nottingham to give me that offer now

  • @fractalprimeeob8703
    @fractalprimeeob8703 8 ปีที่แล้ว +6

    I love when the proff tells stories

  • @r1w3d
    @r1w3d 8 ปีที่แล้ว

    fantastic video :)

  • @lawrencecalablaster568
    @lawrencecalablaster568 8 ปีที่แล้ว +5

    If they haven't already got a video about mercuric sulphide (cinnabar) and alchemy, I'd like to see that. If they've already done that & I just didn't know, my second idea is about either benzene or sodium polyacrylate.

  • @313sib
    @313sib 5 ปีที่แล้ว +1

    Best story i ever heard about it was that Woodward, at some frustrating point in his attempt to synthesise it, was reputed to have said "we'll either make it or I'll take it".

  • @nigeljohnson9820
    @nigeljohnson9820 8 ปีที่แล้ว

    Please produce some videos on the instruments used in chemical analysis and how chemical structure is deduced. It would also be interesting to see something on named reactions.

  • @gsurfer04
    @gsurfer04 8 ปีที่แล้ว +4

    You should do a video about the most complex molecules that the Nottingham crew have made.

  • @leestuurmans2837
    @leestuurmans2837 8 ปีที่แล้ว

    Fascinating!

  • @aosteklov
    @aosteklov 8 ปีที่แล้ว +3

    I would love to see more videos about interesting molecules. NH3 really need one ;-)

  • @Chrizzletrizz
    @Chrizzletrizz 8 ปีที่แล้ว

    Lovely video as always... though I find sound-levels very low :-)

  • @Markle27
    @Markle27 8 ปีที่แล้ว +3

    Featuring my old organic chemistry professor - Philip Magnus! That guy is a genius.

  • @MrTigaente
    @MrTigaente 8 ปีที่แล้ว

    Please more videos with Rob :)

  • @TheAlexagius
    @TheAlexagius 8 ปีที่แล้ว

    Collective synthesis of natural products by means of organocascade catalysis is the name of the mcmillian paper if you are interested, though i needed to use an institutional access to get hold of it

  • @grahamrdyer6322
    @grahamrdyer6322 8 ปีที่แล้ว

    Very Interesting, But what happened to the Ricin Video ?

  • @videogaminbiker889
    @videogaminbiker889 8 ปีที่แล้ว +36

    high security containment system lol 5:20

  • @jam99
    @jam99 8 ปีที่แล้ว

    Really great video, but did I miss the question of whether any positive uses had been found for strychnine?

  • @Infernoraptor
    @Infernoraptor 8 ปีที่แล้ว

    Just thought of something, could you guys do a video at some point about how to determine a molecule's structure?
    Especially the "old-fashioned" way that the they had to use back in the day (since that one probably is less complex to understand).

  • @BurkiesWorld
    @BurkiesWorld 8 ปีที่แล้ว +5

    Make a video on Tetrahydrocannabinol

  • @Cloudstrife2055
    @Cloudstrife2055 8 ปีที่แล้ว

    How about a similar video going over the structure and info on witch hazel?

  • @HominidMachinae
    @HominidMachinae 7 ปีที่แล้ว +5

    A slight correction: because of its effects on the receptors strychnine IS a PNS stimulant, so it is a marginally effective as an athletic enhancer, muscles contract more forcefully. The problem is that the theraputic index is razor sharp. A report from a student that suffered a mild intoxication while using it as a stimulant attest to its effects at slightly supra-theraputic doses, even after he sedated himself with bromide.

  • @Ptro001
    @Ptro001 8 ปีที่แล้ว

    Can you do a video on metallic nanoparticles, and surface plasmon resonance?

  • @Carbocats
    @Carbocats 8 ปีที่แล้ว

    Please make a video about ferrochelatase. Our course is using it to learn protein structure and function.

  • @gargoyle7800
    @gargoyle7800 4 ปีที่แล้ว +4

    How does the plant make such a complex chemical compound.

    • @blueisnotgreen7258
      @blueisnotgreen7258 4 ปีที่แล้ว

      Complexity is in no way linked to Biological or non-biological origin. Also strychnine is not very complex. It’s only slightly more complex than sugar. I can think of hundreds of chemicals that are produced by plants that are far more complex

    • @lyrimetacurl0
      @lyrimetacurl0 4 ปีที่แล้ว

      @@blueisnotgreen7258 if you're talking about proteins, those are directly made via code (DNA) so they don't count. Considering that, would your opinion be different?

  • @Lillebroor
    @Lillebroor 8 ปีที่แล้ว +12

    Vanderwal is a great name when you work with this kind of stuff =D Kinda funny.

    • @TheSam1902
      @TheSam1902 3 ปีที่แล้ว

      The force is strong in this one

  • @chrishenniker5944
    @chrishenniker5944 7 ปีที่แล้ว +3

    One of my favourite songs is Strychnine by The Sonics.

  • @MasterRyu3
    @MasterRyu3 8 ปีที่แล้ว +12

    Is there an antidote or something to negate the deadly affects once it enters the bloodstream?

    • @leogama3422
      @leogama3422 2 ปีที่แล้ว

      I don't think so. But at least you could be put in sedation with a mechanical ventilator until the toxin washes out your body.

  • @fairpoint8158
    @fairpoint8158 8 ปีที่แล้ว

    We would like to see a video of the new types of compounds like tungsten ditelluride and others that are being recently discovered.

  • @nuck-
    @nuck- 8 ปีที่แล้ว

    Oh professor, how we've missed you!

  • @marknikolich6986
    @marknikolich6986 8 ปีที่แล้ว

    Can You do a Video on Fluoroantimonic Acid? Thanks & Keep Up the Great Videos! PS. I Know You can Really do any Experiments with it...

  • @winmine0327
    @winmine0327 8 ปีที่แล้ว +17

    Some folks like water, some folks like wine...

  • @yash96819
    @yash96819 6 ปีที่แล้ว

    do a video on top5 most complex molecules

  • @marclink0
    @marclink0 8 ปีที่แล้ว

    If there is enough to talk about it, could you do a video on capsaicin?

  • @Diggnuts
    @Diggnuts 8 ปีที่แล้ว

    What a nice coinkydink.. I listened to the Sonics song Strychnine just about an hour ago!.
    "Some folks like water, some folks like wine, but I like the taste of straight strychnine"

  • @aapeli4824
    @aapeli4824 7 ปีที่แล้ว

    where did you get the parts of building your own molecules? or did you just make the parts by yourself?

  • @16m49x3
    @16m49x3 8 ปีที่แล้ว +27

    I read: Daily Strychnine

    • @Hamletstwin
      @Hamletstwin 8 ปีที่แล้ว +1

      +Haiiry Cake So...I'm not supposed to sprinkle it in my coffee? uh-oh

    • @MephLeo
      @MephLeo 8 ปีที่แล้ว +1

      +Haiiry Cake Back in the day it was pretty much it. Silly Victorian people.

    • @Roxor128
      @Roxor128 8 ปีที่แล้ว

      +Haiiry Cake
      If you're a drug dealer who hates their customers, it could very well be.

    • @Joemenix
      @Joemenix 8 ปีที่แล้ว

      +Haiiry Cake DAILY DOSE

    • @MuzikBike
      @MuzikBike 7 ปีที่แล้ว

      I need my daily dosage of this

  • @apenasmeucanal5984
    @apenasmeucanal5984 8 ปีที่แล้ว +83

    He should use snatoms instead of those stick molecule things

    • @collinbardini
      @collinbardini 8 ปีที่แล้ว +47

      +apenasmeucanal Yes, and it would only cost $168 to make this molecule using those.

    • @lambdabaryon
      @lambdabaryon 8 ปีที่แล้ว +2

      Well he could use molymods

    • @tinuszke
      @tinuszke 8 ปีที่แล้ว +5

      +apenasmeucanal If I understand correctly, there is no Nitrogen available yet, only C,H,O.

    • @tyler111762
      @tyler111762 8 ปีที่แล้ว

      +Tijn van Boekel there isn't

    • @tru7hhimself
      @tru7hhimself 8 ปีที่แล้ว +6

      +apenasmeucanal you cannot make these rings with snatoms. they'd be intuitive for the very simplest of organic molecules, but even for the basic building blocks of life you need a more powerful visualisation tool that can actually model double bonds.

  • @Alderak1
    @Alderak1 5 ปีที่แล้ว +2

    Strychnine was used by a professional runner for the first Olympic marathon in St. Louis. He didnt win the race. At the end of the race he was severely sick, dehydrated, and even delusional.

  • @isaacleach1
    @isaacleach1 8 ปีที่แล้ว

    Two new syntheses of strychnine were very recently published which consist of 10 steps with a 14% yield and 8 steps with a 10% overall yield! Exciting stuff. Beemelmanns et al, July 29 2015, in The Chemical Record

  • @kalimsheikh2494
    @kalimsheikh2494 8 ปีที่แล้ว

    Pls make a video on revolutionary catalysts. :)

  • @gabor_kov
    @gabor_kov 5 ปีที่แล้ว

    what kind of model was used? i would really like to know please.

  • @WhiteKestrell
    @WhiteKestrell 8 ปีที่แล้ว

    My Favorite poison! Thank you PV :)

  • @athomp07
    @athomp07 8 ปีที่แล้ว

    Speaking about rat poison, it would be cool to see a video about Warfarin. An interesting piece of historical trivia is that the discoverer, Frank Schofield, was both a veterinarian and a major figure in the liberation of Korea from the Japanese Empire (a story most Ontario Veterinary College graduates have heard several times).

  • @RyanDB
    @RyanDB 8 ปีที่แล้ว

    It's maybe not immediately relevant to the video, but I was learning about 2D NMR techniques earlier today. Really interesting stuff, but I need a lot of practice interpreting the spectra I think.

  • @cOmAtOrAn
    @cOmAtOrAn 8 ปีที่แล้ว

    Is their any practical reason to WANT to synthesize strychnine, or is it just for the challenge of it?

  • @qwertyasdf66
    @qwertyasdf66 8 ปีที่แล้ว

    What's the significance behind the colours of the numbers on the clock in the background?

  • @jimscobie6646
    @jimscobie6646 5 ปีที่แล้ว

    Fascinating

  • @dustinsc2023
    @dustinsc2023 7 ปีที่แล้ว

    Very awesome

  • @bcfuerst
    @bcfuerst 8 ปีที่แล้ว

    Arsenic was also used as performance enhancing drug at least since the middle ages in certain regions of Austria. heavy workers would take it or it was mixed into animal feed.

  • @seannot-telling9806
    @seannot-telling9806 5 ปีที่แล้ว

    I like the way the office is kept with books and things everywhere.

  • @jameskiller1000
    @jameskiller1000 8 ปีที่แล้ว

    On a side note, Viresh Rawal (University of Chicago) also synthesize this molecule back in the late 1980s/early 1990s and the overall yield is also quite respectable.

  • @dots5641
    @dots5641 8 ปีที่แล้ว +1

    Makes sense that it takes bitter, since we evolved to distinguish poison from food thousands of years ago.