A New Flexible Photoplethysmography (PPG) Sensor Patch for Continuous Measurement of Blood Flow and

Title: A New Flexible Photoplethysmography (PPG) Sensor Patch for Continuous Measurement of Blood Flow Volume and Pressure based on AI algorithms
Author: Paul C.-P. Chao
Affiliation: National Chiao Tung University, Taiwan
Abstract: A new flexible hotoplethysmography (PPG) sensor patch measuring blood-flow volume (BFV) and blood pressure (BP) based on AI algorithms is successfully designed and prototyped. With this patch, the measurement on BFV and BP is non- invasively, and can be continuously collected over more than 24 hours, resulting in valuable long-time monitoring data for medical diagnosis. These long-time, continuous BVF measurements are particularly important for monitoring the quality of an arteriovenous fistula of a hemodialysis patient for prognosis. As opposed to the developed patch, an expensive and bulky BFV monitor is commonly adopted in clinic practice as a gold standard for BFV measurement once per months. The instrument needs to be operated by professional, well-trained medical personnel. The PPG sensor patch developed is instead a low-cost, small-sized, wearable, and easy-to-use sensor that is capable of continuously measuring BFV and BP via AI algorithm. New designs of front-end analog circuit, signal processing, and an intelligent neural network calibration method are employed to achieve high correlations of R2 = 0.88 for BFV and R2 = 0.85 for BP, as opposed to their gold standard counterpart monitors.

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