How 'Microclots' Fit Into the Long Covid Puzzle | With Prof. Resia Pretorius and Prof. Doug Kell

แชร์
ฝัง
  • เผยแพร่เมื่อ 23 ธ.ค. 2024

ความคิดเห็น • 318

  • @scripturethroughancienteye1509
    @scripturethroughancienteye1509 2 ปีที่แล้ว +30

    Gez you and these medical professionals provide such an invaluable service. Thank you!

  • @Franklytiredout
    @Franklytiredout 2 ปีที่แล้ว +25

    Yes re medicine in silos!! Saw a cardiologist who seemed disgusted that I couldn’t do a treadmill stress echo. Tried to tell her about my symptoms generally started with my lungs. She said “no I don’t do lungs just heart. Let’s stay on topic here.”. Horrible woman. Stress echo with the drugs and with her total lack of regard for me was deeply traumatic.

    • @RUNDMC1
      @RUNDMC1  2 ปีที่แล้ว +4

      What an awful experience Gael!

    • @stephaniewilson3955
      @stephaniewilson3955 2 ปีที่แล้ว +5

      Report her. There will be a way.

    • @Jennifer-gr7hn
      @Jennifer-gr7hn 2 ปีที่แล้ว

      They're all gaslighting narrow minded, lack of critical thinking robots who work for the system. period. Get out of the system and do other things -- functional medicine, IV ozone, chelation, HBOT, etc. Forget them all. I had to. I"m too ptsd for all this insanity, and....the playing dumb

    • @juliesauve6719
      @juliesauve6719 2 ปีที่แล้ว

      😓

    • @juliesauve6719
      @juliesauve6719 2 ปีที่แล้ว

      They do only what they are trained to do. Have not found a LC specialist.

  • @flagmichael
    @flagmichael 2 ปีที่แล้ว +16

    Another remarkable video about what we know so far. I love the multidisciplinary approach - I don't know about anybody else but I sure don't feel like a museum with a heart, a couple lungs and kidneys, a brain... gathered in a bunch of rooms. The "silo" visualization does a good job of illuminating the absurdity of the way patients are treated today.

    • @teddybearroosevelt1847
      @teddybearroosevelt1847 ปีที่แล้ว +1

      Well, the absurdity of that siloization has also brought about the best medical science any civilization has come up with. I don’t know about you, but if I get say cancer I’d rather have a western specialist treat me and only if that doesn’t cure me I’d look to Ayurvedic or Chinese approaches.
      Which is not to say that it doesn’t have its downsides of course. GPs could stress the value of healthy food, stress reduction, loving relationships, etc.

  • @Turtledove2009
    @Turtledove2009 2 ปีที่แล้ว +10

    Such good questions being asked. I will listen to this series several times because I think understanding microclots in Long Covid seems to be very important. Thanks again Gez!

    • @RUNDMC1
      @RUNDMC1  2 ปีที่แล้ว

      Thanks Erika!

  • @comicbossone2411
    @comicbossone2411 2 ปีที่แล้ว +8

    Another great video. Dr Khan is looking like a champ now!

  • @dianalapointe5501
    @dianalapointe5501 2 ปีที่แล้ว +17

    Thanks Gez for more research for all of us! With my brain fog I have a hard time following much of the discussion but it gives me hope that there are those more capable than me working on this. I did get Covid again in June and it sent me right back to my first Covid symptoms in March 2020. I ended up at the emergency room for the first time because I was having a hard time breathing. They gave me Paxlovid and by the time I finished the course I felt probably the best I had felt in this whole 2 1/2 years! For a couple of days I had all kinds of energy and did things I hadn’t been doing for quite a while. Unfortunately, after two or three days that wore off and I was as bad as I had been and my nurse practitioner gave me another round of paxlovid. Unfortunately, that one didn’t work nearly as well as the first course and I spent the rest of the summer way worse than I had been prior to getting Covid the second time. It was pretty bad. I am now almost back to where I was before getting it again, although I feel like the crashes are worse. Thanks for everything.😊

    • @Tinyteacher1111
      @Tinyteacher1111 2 ปีที่แล้ว

      My son gets crashes or flares, and it’s horrible!

    • @RUNDMC1
      @RUNDMC1  2 ปีที่แล้ว +3

      Wishing you the best in your recovery Diana

    • @backalleygaming7096
      @backalleygaming7096 ปีที่แล้ว

      What did you do in between to get better ?
      Im in Australia and its pretty hard to get paxlovid, though I wish I can... I had the other version called mirprovirl or somthung, and that didn't get much, only first 3 days I was good then things went to crud

  • @spion92
    @spion92 2 ปีที่แล้ว +4

    You are a godsend and Hero, Gez! Without you and these wonderful doctors work, we would all still be in the dark.

    • @RUNDMC1
      @RUNDMC1  2 ปีที่แล้ว

      Thanks Alex!

  • @billfricker4368
    @billfricker4368 2 ปีที่แล้ว +4

    Thank you for another wonderful presentation. Starting to understand the parasthesia in my calf and foot which happened a few months in. It will never go away but understanding how and why is comforting.

  • @Anamaria-ew8lh
    @Anamaria-ew8lh 2 ปีที่แล้ว +5

    I'm looking forward to see the next post. Thank you very much for sharing the wisdome!

  • @sharongibson7523
    @sharongibson7523 2 ปีที่แล้ว +7

    Hi, its getting very technical but still following. Thank you. When it all started kicking off in the UK March/April 2020 there was a headline that Italian doctors were reporting it was blood clotting disease and not respiratory disease, they had done post mortems when the UK werent doing them. Not sure if anyone listened at the time.

    • @flagmichael
      @flagmichael 2 ปีที่แล้ว +1

      It was known in 2020 that endothelial cells were targets of the virus by virtue of their ACE2 receptors. two years later we still don't know (institutionally) what to make of it all.

  • @turbostream7925
    @turbostream7925 2 ปีที่แล้ว +21

    I think this channel is the go to for Long COVID info, no one else is covering it with such detail. Well done Gez for continuing with it.
    I had to tell my Dr it might be long COVID last year, he said come back if gets any worse!
    Anyway I caught COVID in October and was ill for a week. Is it possible that a second infection can clear out long COVID as I have all my previous my energy back? Fingers crossed I'm am ok now after 18 months of it.

    • @flagmichael
      @flagmichael 2 ปีที่แล้ว +2

      I agree - this channel is the best by far for Long Covid information. I am not a sufferer but I see it as a very serious problem not only for the sufferers but for society in general. The prevalence means lots of people in about as many families are affected. There isn't even agreement about how many people are affected, how many in each level of severity, how many have effectively recovered, or even what recovery actually looks like. After more than two years of international COVID Gez's channel is still the single best source for information on this incredibly frustrating syndrome.
      If you have missed any of the episodes here, by all means watch them. Could the second infection have helped? Nobody here would rule it out, I bet. Frequently second infections mean setbacks but everybody is different.

    • @victoriahouse9969
      @victoriahouse9969 2 ปีที่แล้ว

      I've had Covid-19 3 times. Long Covid has continued since first infection. 32 months now. I don't think Long Covid will disappear because you've had Covid for a second time. Your body will take time to heal from each infection. I'm not sure where I'm going to get rid of Long Covid. I wish I did know.

    • @Feirin332
      @Feirin332 2 ปีที่แล้ว +2

      In my case contracting Covid again also initially led me to feeling much better at first, only to be followed with long Covid all over again. Crossing fingers that things will work out better for you.

    • @turbostream7925
      @turbostream7925 2 ปีที่แล้ว +2

      @@Feirin332 oh dear sorry to hear that. I will be taking it steady till I'm sure.

    • @denisau3646
      @denisau3646 2 ปีที่แล้ว +1

      I know several pple who had Covid a 2nd , 3rd, 4th time - some were cured of their Long Covid, some were not. Puzzling..

  • @smalle
    @smalle 2 ปีที่แล้ว +6

    This is exciting how many people and conversations you announced at the end of the video. It feels like the ball may have just crested the hill and is finally starting to roll.

  • @cquarman
    @cquarman 2 ปีที่แล้ว +4

    Fascinating. Incredibly grateful for the work of these two. Look forward to the enzyme episode.

  • @ChildofGod98765
    @ChildofGod98765 2 ปีที่แล้ว +45

    Being a single mother isn’t easy. I’m overwhelmed because both of my children are autistic. I’m struggling trying to support them and myself because like so many others. I lost my job as a social worker at Forsyth hospital because I declined the vaccine. I declined because of my pre existing health condition lupus and heart disease. I was denied my medical/religious exemption. I wish I could go back to the hospital but the mandate is still in place for hospitals that participate in Medicare and Medicaid. I’m waitressing and I’m so thankful to be working again, but I’m not making nearly enough to make ends meet. But God continues to help me. I get harassed and called names for simply asking for prayers, but prayers are all we need and when you’re a real christian people will always crucify you. Thankfully God gives me strength to keep going. I have faith God will provide. He HAS THIS FAR. WITH GOD ALL THINGS ARE POSSIBLE! Please pray for me and my children.

    • @LB-sw2km
      @LB-sw2km 2 ปีที่แล้ว +4

      I am praying for you .
      I myself raised 4 children alone . My husband passed away . I trust and believe in God . He has helped me with all my needs and even my wants . When it seemed like I had no way to pay .. a way was always made.
      Also I had COVID . I had it for a month . I would have been put on a respirator if I had went to the hospital. Instead I stayed home and trusted Jesus Christ. Fear kills ! Fear feeds death! What is death ? Not God ‘ it’s Satan! God is the giver of life . He is life!
      Feed life ! Trust Him the giver of all good things.
      Don’t feed the devil or be in agreement with him .
      Praying for healing praying for deliverance and praying for your way to take care of yourself and children. In Jesus name .

    • @Tinyteacher1111
      @Tinyteacher1111 2 ปีที่แล้ว +2

      You have my prayers! Prayers work, even if you don’t see the way they are working.
      I need them for my son, and I’m sick as well. I can’t understand this, but I have to have faith in the end result. 🙏💕💫

    • @carolenmarch7445
      @carolenmarch7445 2 ปีที่แล้ว +2

      Sweetheart, is there a church fellowship that can help you out with some basic things like food parcels and pastoral support for yourself and your kids. I'm in the UK and good churches here can provide this kind of support. I pray for a way through for you and your family . God bless.

    • @carolenmarch7445
      @carolenmarch7445 2 ปีที่แล้ว +1

      Yay! You've advertised your book again , well done ! I'm sure it will bring relief and comfort to many. Very interesting that micro clots are the end points of mitochondrial dysfunction and endothelitus; l was wondering how those 3 could match up to one another. Antioxidants ( polyphenols and flavenoids present in fruits and vegetables
      ...think blueberries !) and enzymes ( nattokinase , sereptase ) are the pharmaceuticals available to us now over the counter, but drug trials are definitely needed together with a cheap , fast diagnostic test for micro clots that GPs can access . Great vid Gez !

    • @barbarasaunders2160
      @barbarasaunders2160 2 ปีที่แล้ว

      Sending prayers to you and your children.

  • @timmyschannel5
    @timmyschannel5 2 ปีที่แล้ว +9

    How do you get tested for microclots or endothelial damage ?

    • @RUNDMC1
      @RUNDMC1  2 ปีที่แล้ว +1

      Check out episode 2

    • @timmyschannel5
      @timmyschannel5 2 ปีที่แล้ว +1

      @@RUNDMC1 thank you, see there are two places in the UK. I'm in Ireland. Can anybody send them bloods ? Would they accept them? Maybe no, maybe blood has to be tested quickly !

  • @lesliec8069
    @lesliec8069 2 ปีที่แล้ว +2

    Thank you Gez for this valuable segment.

    • @RUNDMC1
      @RUNDMC1  2 ปีที่แล้ว

      Thanks Leslie!

  • @risecopeman5409
    @risecopeman5409 2 ปีที่แล้ว +8

    My daughter can't wait for confirmed diagnosis!!! Or a perfect study!!! She is losing weight and hope every day!! Micro clots cause ischemia in the intestines, too. She doesn't have much time left with the rate she is going. HELP!

  • @JagHiroshi
    @JagHiroshi 2 ปีที่แล้ว +3

    Glorious work as always. Eventually, we will find a way out of this - and we must learn the lessons regarding agility and multidisciplinary working in time for the next challenge.

  • @Unitedstatesian
    @Unitedstatesian 2 ปีที่แล้ว +7

    Yes! Objective testing to diagnose LC is key! What measures are they using in the Paxlovid trials? Doing microclot and endopat tests every five days might be key in deciding the dose and duration needed.
    Is the elimination of microclots the cure? I doubt it. Microclots are probably downstream of the larger issue. I think the problem is upstream ....Endothelial damage> viral debris or persistence >> Immune dysfunction >>> physiological damage to the limbic system causing it to be stuck in a fight or flight loop.
    And, if PEM and crashes are caused by reperfusion injury then it is key to move slowly in recovery (no wonder drugs) and PEM/crashes are actually a "good" sign (oxygen is getting to areas it does not normally get to). This means that the "neuroplastic brain training" method is the right path. A Big crash is bad, we pushed too hard, but no use stressing over it (rest and push less). Small PEM after slightly pushing yourself = good...rest and then keep pushing in "microsteps", but only after getting the basics down (sleep, diet, pacing, emotional regulation, etc...).
    This would also explain why triple-therapy is only partially successful. Just mops the floor without turning off the tap. And it might be too much too fast, causing reperfusion injury???
    Personally, I have reduced my aerobic effort (less walking) and replaced it with a very slow progression of building muscle mass. I feel like it is working. It is very slow, but each day I feel stronger. I am also doing self-designed micro-HiiT = walking quickly up a flight of stairs... to get my heart rate up for a few seconds on purpose which is a level of effort I can deal with a few times a week. So far it is working. Also, key to note is following the 80% pacing rule to leave energy for healing and an extended fast which helped clean out a lot of junk and it gave me a bump of 10% in my energy baseline.

    • @IThinkICare
      @IThinkICare 2 ปีที่แล้ว +1

      I agree with a lot here but until we know why the endothelial cells are damaged, I wouldn't say brain retraining can be a solution. I think there are endothelial cells in the brain, but repairing it should not be brain training, but ....well I don't know. The fight and flight stuff may have to do with inflammation but clearly has to do with psychological issues (anxiety).
      On the pushing yourself to crash point, doesn't make sense to me.
      The only thing I can think of helping the issue may be increased blood flow. Like thinner blood. More muscles only going to need more oxygen. Crashing only forces you to rest more, so how about resting more without crashing?! It has it's limits as our body need to more and increased flow may be good.
      Looked into this reperfusion ..... not sure. I don't think there was complete lack of oxygen. Only lower levels and maybe that started some kind of disfunction and rebalancing. I don't understand this part, but it is interesting as I wonder if others have noticed similar PEM like me. Over many years. First it was like PEM on a weekly basis. I could do 5 days of activity if I kept thing to a minimum. then 2 days of crash kind of a recovery. Then 10 years later it got to 3 days. If I over do it today, I will fell worse the day after tomorrow. So very individual, depending on condition (mine are a lot worse now).
      The worse for me the in-between. When I don't feel well and can't do much but I don't feel sick and I can't rest. Many hours a day are like that, but at least after many years, there are people working on it. I thank them.

    • @Unitedstatesian
      @Unitedstatesian 2 ปีที่แล้ว

      @@IThinkICare Knowing the exact cause of damage to the brain is complex. Maybe we will never know. However, the body functions in loops. If we correct one point in that loop, we can improve the whole loop and there is a snowball effect. There might be many points on the loop that can be improved with diet, sleep, movement, rest, etc... Why not also use the most powerful point (limbic system) and work on improving from that point as well?
      The default in out limbic system is negative (a bias for survival), but we can train to change that bias to positive and have a huge impact on energy! We need to conserve energy in any way possible to heal.

    • @IThinkICare
      @IThinkICare 2 ปีที่แล้ว

      @@Unitedstatesian Exactly, but it should be clear that I was talking about physical damage in the brain that can be overcome by neural plasticity. If we find to heal this area by healing the cells, then we can look at what physiological damage is left and deal with that separately. While we are managing, both can help, but one of the problems is that it's very subjective. A lot of effort goes into it and hard to follow it's progression. Biomarkers are more factual.

  • @willscarlet9823
    @willscarlet9823 2 ปีที่แล้ว +1

    Sorry just got to add this yesterday I went up to Edale in the Peak District, I had no expectations but a drive, it was cold windy but 14.5 miles later I arrived back at Edale, no speed no personal best, lots of sit downs but no crash! I haven't done this in over 2 years!, seriously am I fixed?? Continuing with aspirin b3 and nac

    • @RUNDMC1
      @RUNDMC1  2 ปีที่แล้ว

      If you don’t get any PEM you’re at the least well on the way!

  • @christinekorol8793
    @christinekorol8793 2 ปีที่แล้ว +1

    Hi Gez! At 9:46 in this video, you had just asked Assad about what dream drugs they’d like to see trialed. When Assad answers, the audio is really fuzzy and I can’t make out the name of the drug he responds with (the one being studied by Tunisian group). Could you let me know what he is saying? Thanks : )
    Also, huge kudos to you on this video series. It’s nice to see all the research I’ve been following throughout my debilitating 16 months of long Covid being expressed so succinctly. You’re doing such a great job that I don’t feel I need to buy your book, but am ordering one as a Christmas present to myself to support the work that you’re doing. Thank you for the work and advocating you are doing.
    Can’t wait to be on the other end of my recovery journey and able to advocate for other long haulers as well. 🎉

    • @RUNDMC1
      @RUNDMC1  2 ปีที่แล้ว

      Hi Christine - Asad mentions Sulodexode. Thanks for the support!

  • @risecopeman5409
    @risecopeman5409 2 ปีที่แล้ว +6

    The loss of my daughters leg muscles, when she tried to continue dance classes, was so abrupt, so shocking. Something had to be killing her muscle cells. Her feeling of having extremely over worked when in the past that level of work was nothing and would have only caused an increase in muscle. The micro clots causing low oxygen causing cell death, plus no energy coming from mitochondria.... that makes total sense and matches her physical experience and sensations. How can we get her in the Recover study?

    • @scripturethroughancienteye1509
      @scripturethroughancienteye1509 2 ปีที่แล้ว +6

      My legs felt so terrible, like they were so weak. It eventually got to a point that I could hardly walk. I know very well the hardship. I have recovered, however, and I hope she will too.

    • @janybekorozaliev9052
      @janybekorozaliev9052 2 ปีที่แล้ว +2

      @@scripturethroughancienteye1509 how long did it take you to recover?

    • @scripturethroughancienteye1509
      @scripturethroughancienteye1509 2 ปีที่แล้ว +3

      @@janybekorozaliev9052 Weakness in my legs went away in about nine months. It came back a few months later. A month later it was gone for good and never came back. Other symptoms varied. Two years and one month since my infection. I basically only have the tinnitus now. Niacin, Baby aspirin, prayer. And when I was able to do so I did a small bit of working out. It would make me relapse some times but then I'd try it again when I was able to.
      What other symptoms does she have besides the legs?

    • @risecopeman5409
      @risecopeman5409 2 ปีที่แล้ว +2

      She has gastrointestinal pain, nausea, loss of appetite, constipation, weight loss, 5'6" but only 105 lbs, very low blood pressure laying down or standing up along with fast heart rate, light headed,, brain fog,, intermittent body pain, headaches, malaise, growing depression, plus Intermittent other symptoms. Positive ANA, negative on all else. She was treated for h pylori, now on a round of prednisone (causing diarrhea), weekly IV saline. She was strong and active, smart and beautiful. She is trying to hold on, but just can't eat, drink, gain weight....

    • @eugeniebreida
      @eugeniebreida 2 ปีที่แล้ว +5

      @@risecopeman5409 What do I know, but very high end pre and probiotics seem in order. I am so sorry!
      Rest, rest, hydrate, rest….
      Deep breathing, gentle massage, listen to Rain on youtube to help fall off to sleep/deeply relax.
      Sending hugs!

  • @IamLinda_
    @IamLinda_ 2 ปีที่แล้ว +9

    I'm almost 28 months in and I'm still getting my @ss kicked by PEM! In the US, we just had Thanksgiving on Thursday. In addition to the dinner, I had 3 hours of driving. That one day cost me the next 48 hours. I still can't do anything that deviates from my normal day, which is just sitting in my livingroom.
    I have not gotten any of the tests for Long Covid so I can't be 100% sure that my PEM is caused by LC and not the kidney damage that I developed after Covid since both cause fatigue. I have been on Eliquis since before I got covid, so if I have microclots, the Eliquis didn't prevent them.
    If anyone needs a test subject or a guinea pig, I volunteer!

    • @vanjacalantropo
      @vanjacalantropo 2 ปีที่แล้ว +1

      @I am Linda I wonder if there is a difference between LC population who has PEM and those who don’t. Not sure if there are studies…

    • @kapaul1584
      @kapaul1584 2 ปีที่แล้ว +2

      I'm right behind you at 27 months. No end in sight, the PEM is terrible.

    • @kapaul1584
      @kapaul1584 2 ปีที่แล้ว

      @@vanjacalantropo Good question, I used to think everyone is like me with PEM but now I know there are plenty with other symptoms.

    • @vanjacalantropo
      @vanjacalantropo 2 ปีที่แล้ว +1

      @@kapaul1584 what are the symptoms of PEM?

    • @flagmichael
      @flagmichael 2 ปีที่แล้ว +4

      The PEM problem is one that society around the world is not taking nearly seriously enough. In a single stroke there has been a significant number of partially or functionally disabled people who were contributing to public vitality just a few years ago. As bad as that is, it is even worse to be one who actually has it. The only comfort I can offer is that you are not alone and the large numbers are hopefully going to get enough resources drawn to figuring this out.

  • @ailsa7555
    @ailsa7555 2 ปีที่แล้ว +4

    Iscimia reperfusion injury is the first explaination that actually makes sense for PEM symptoms. Do you know of any studies that look at cardiac output or low blood volume in long covid? I think that would also contribute to the issue.

    • @RUNDMC1
      @RUNDMC1  2 ปีที่แล้ว +1

      We’ve had studies showing cerebral hypoperfusion but that’s not quite the same thing

  • @cwebbwash3
    @cwebbwash3 ปีที่แล้ว +1

    Microclots have been a central focus among many scientists/doctors for a while now. I can't believe there's still no test for this or wider knowledge support to dig deeper in 2023

  • @fashionmixtapes
    @fashionmixtapes 2 ปีที่แล้ว +2

    7.28 Nattokinase or ?? can't tell what she says at that point

  • @janeworroll4770
    @janeworroll4770 2 ปีที่แล้ว +1

    And thanks to all in the video for the update and hard work x ( ive pretty much given up on the LC clinic and GP not much on offer now for me, i can live with the quirks better now than before, but lets hope in time things change esp if living with issues leads to or increases future illness 😬)...& breath 🙏

  • @epicchannel4724
    @epicchannel4724 2 ปีที่แล้ว +2

    Have any long haulers tried Curcumin?
    Have read a few positive studies on its effects on endothelial cells.

    • @teddybearroosevelt1847
      @teddybearroosevelt1847 ปีที่แล้ว +2

      Yes, I have. Unsure if it has any beneficial effect, but I don’t feel a negative effect from it either

    • @epicchannel4724
      @epicchannel4724 ปีที่แล้ว

      @@teddybearroosevelt1847 I had chronic back pain for almost 20 years and thought I was going to end up out of work. Took CBD on and off but didn't feel like it worked. It wasn't until I received a large amount for free that I repeatedly took it every day. Took about 4 months before I really noticed a dramatic easting of pain and discomfort and a year before it was almost completely gone. Discovered that curcumin had a lot of similar flavonoids and far less expensive and have stuck with it. CBD and Curcumin have a progressive and accumulation effect and don't act like over the counter drugs.
      Honestly worth sticking with long term.
      Can I ask if you have tried niacin or nicotine gum at all?

  • @vanjacalantropo
    @vanjacalantropo 2 ปีที่แล้ว +4

    Thank you Gez, the clots are ongoing but people are getting better. Are clots active and present only while viral persistence and spike protein lasts? They are set to study paxlovid in LC in the US.
    Your book is a great resource! Thank you!!!

    • @RUNDMC1
      @RUNDMC1  2 ปีที่แล้ว +3

      We don’t know, in answer to your question! And thanks for the support re the book :)

    • @Jennifer-gr7hn
      @Jennifer-gr7hn 2 ปีที่แล้ว

      This American will NOT take a medication from the people who refused to prescribe EYEvrMk10! Period.

  • @jerrygao458
    @jerrygao458 2 ปีที่แล้ว +3

    Thank you, Gez. From the previous video, I followed low histamine diet and having antihistamine, my night palpitations and GI issues got improved. Still, I am having the pots symptoms, and I think it is caused by the micro clots. Because my cardiologist confirmed I did not have pots. But in New Zealand we do have the test for Endothelial function test. I think the Endothelial injury is the important puzzle of my recovery. But I am not sure what supplements or drugs need to have a try.

    • @francolman2379
      @francolman2379 2 ปีที่แล้ว

      Hi from Oz. Can I ask what the Endothelial test is called in NZ. Not aware we have anything like that here.

    • @RUNDMC1
      @RUNDMC1  2 ปีที่แล้ว +3

      Treatment film coming next - along with enzymes film to follow 👍

    • @jerrygao458
      @jerrygao458 2 ปีที่แล้ว +1

      @@francolman2379 sorry, brain doesn’t work. We do not have the test.

  • @MamaRestInPeace1424
    @MamaRestInPeace1424 ปีที่แล้ว +3

    My Neurosurgeon is a Professor Of Neurosciences at Harvard and has put ne on Nattokinase, Tocotrienols, NAC and Glycine He is convinced there is enough evidence with Nattokinase curbing micro clotting. He also put me on Monolaurin 1,500-3000mg daily for two weeks, then off two weeks. Added with D3 and Magnesium, they are working without a doubt.

    • @venuselectrificata
      @venuselectrificata ปีที่แล้ว

      Hi. Wondering what prompted you to see a neurosurgeon? I’ve been having incredible pressure in my head for the past year now

    • @katherinewilson8007
      @katherinewilson8007 ปีที่แล้ว

      Thanks for info

  • @jrman413
    @jrman413 2 ปีที่แล้ว +3

    Do you have any information on what bacteria in the gut COVID wipes out? Is there any study of that?

    • @RUNDMC1
      @RUNDMC1  2 ปีที่แล้ว

      Not specifically for LC, no

  • @twocanplay7976
    @twocanplay7976 2 ปีที่แล้ว +3

    So is it accurate to say that multiple groups are arriving at a similar conclusion of vascular system issues/ endothelial dysfunction? I read the study from Tunisia that you linked in another comment, and also read a couple other studies of long-haul related endothelial dysfunction. Pursuing this on top of the other avenues such as mitochondrial dysfunction seems like a very promising way forward! I hope to see more results from studying this pathology, it feels like a pretty big breakthrough! Especially since that Tunisian study referenced long haul symptoms improving with sulodexide.

    • @RUNDMC1
      @RUNDMC1  2 ปีที่แล้ว +1

      Yes agreed - v promising way forwards and yes re multiple groups

    • @twocanplay7976
      @twocanplay7976 2 ปีที่แล้ว

      @@RUNDMC1 thank you Gez!!!!!

  • @kim.in.nature.
    @kim.in.nature. 2 ปีที่แล้ว +2

    What about natural healing / strengthening of the blood vessels like Rutin or Horse chestnut? There are more that support the blood vessels too.
    Boswellia or Omega 3 as an ant-inflammatory? Seems drugs have many side effects.
    Thanks for all that you do Gez, sending much love.

    • @RUNDMC1
      @RUNDMC1  2 ปีที่แล้ว

      Might be worth a go but we don’t have any specific science to lean on!

  • @galladiel
    @galladiel 2 ปีที่แล้ว +2

    Thank you very much! One interesting area to pursue would be Methylene Blue in low doses. It has a neuroprotective effect in mitochondria and helps to reduce free radicals. Dr. Mobeen has done a video explaining the mechanism by which it works recently on his channel "Long Story Short". It is named "Methylene Blue and Near Infrared Light for Neuroprotection.

  • @centerrightpunk
    @centerrightpunk 2 ปีที่แล้ว +2

    Another great video. Please do more on this endothelium theory. I'm actually in the RECOVER study myself here in the states.

    • @epicchannel4724
      @epicchannel4724 2 ปีที่แล้ว +2

      Worth looking at the effects of Curcumin on Endothelial cells.

  • @kapaul1584
    @kapaul1584 2 ปีที่แล้ว +3

    How did Dr. Khan do with the blood filtering? We never did here the outcome? Was he cured or was it temporary or did it not work at all?

    • @hannasizemore8028
      @hannasizemore8028 2 ปีที่แล้ว +2

      I’m very interested in how Dr. Khan’s treatment faired, too. I had a radical improvement in my long COVID symptoms around the 20 month mark after donating blood. I donated to bring my sky-high iron levels down - found out I have hereditary hemochromatosis thanks to all the testing for long COVID symptoms. I’m sure that normalizing iron levels was a benefit by itself, but I always wondered if I didn’t benefit from getting rid of micro clots at the same time. I’ve had long COVID symptom relapses from colds and from the booster shot since, so things are still not *fixed*. My doctor and I are continuing tinkering with the iron issues, donation schedule, doses of antioxidants, etc. . . . And just generally trying to think of new things to try. Really hoping Dr. khan got a benefit.

    • @eugeniebreida
      @eugeniebreida 2 ปีที่แล้ว

      @@hannasizemore8028 That’s great - am curious about specifically helpful anti-oxidants-?

    • @hannasizemore8028
      @hannasizemore8028 2 ปีที่แล้ว +1

      @@eugeniebreida NAC and CoQ10 have been the most helpful for me.

    • @kellyberry4173
      @kellyberry4173 2 ปีที่แล้ว +1

      How safe can it be to donate blood if you have longcovid!?!?!?

    • @hannasizemore8028
      @hannasizemore8028 2 ปีที่แล้ว +1

      @@kellyberry4173 Fair question, but I discussed it at length with doctors. They were most concerned about it exhausting me; I was most concerned about donating blood that wasn't amazing for the recipient. I did it at a time when I was feeling *relatively* well and my blood work all looked good except for elevated iron. Everyone involved assured me there was such a need for blood donations, no one who needed a transfusion was going to be fussed about getting a little to much iron. So, I did it and it caused a major improvement that lasted many months. I don't think this is a good approach for long covid generally. It was something that seemed to have a good effect in my highly specific case. It's also worth nothing, that I haven't been able to repeat the experiment, because my B12 and hemoglobin levels have been persistently low, although my iron remains somewhat high. Long covid puts a lot of things out of wack -- and in my case, exposed an underlying problem I hadn't been aware of. My doctors are tinkering very specifically with *me*. But the effect was really pronounced -- everyone who saw me in the days and weeks afterward commented on how I was suddenly like myself again. The improvement seemed out of proportion to the correction in my iron levels. So when I started hearing about the microclot research, I wondered if that wasn't part of the story.

  • @timmyschannel5
    @timmyschannel5 2 ปีที่แล้ว +2

    Hello Gez, do you have any links to papers , research or articles wrote by them on their findings? I'd like to send it onto an immunologist

    • @RUNDMC1
      @RUNDMC1  2 ปีที่แล้ว +1

      Just do a Google for ‘Pretorius scholarly article’

    • @timmyschannel5
      @timmyschannel5 2 ปีที่แล้ว +1

      @@RUNDMC1 thanks Gez

  • @IVFRegulation
    @IVFRegulation 2 ปีที่แล้ว +2

    All or most of antidepressants have modulatory effects on platelets usually shown as a reduction in platelet numbers... It would be great to check their opinions on these drugs, especially since there are some long covid patients who notice some improvement after taking these drugs...Thank you for the best videos and info about covid!

    • @clairegillies7919
      @clairegillies7919 2 ปีที่แล้ว +4

      They also come with an increased risk of dementia - alter brain chemistry - and are in many cases addictive so withdrawal is horrific for patients. Strangely this is over looked in those already hooked and a conversation GP's swerve and assure patient's it's 'not common'...imo taking these is adding another layer of problems to existing LC issues.

    • @alananives4060
      @alananives4060 2 ปีที่แล้ว +4

      That's unfortunately true, be very careful in starting antidepressants, they can cause severe withdrawal.

    • @Jennifer-gr7hn
      @Jennifer-gr7hn 2 ปีที่แล้ว

      You nailed why I was feeling greater lung capacity and less PEM when on short term Fluoxetine with the chronic covid treatment center, My platelets continue rising, along with my antibodies.

  • @snufkin544
    @snufkin544 2 ปีที่แล้ว +1

    Thank you again, Gez. Great to see Asad too.
    Talking about seeing microclots, I am off for a QV chest scan on Weds (my birthday so hope it's not too awful!) which includes an injection of a radioactive substance. I don't have the leaflet through the post as I think I'm being fitted in, having waited for 16 months after a recommendation by the HR CT scan person. Does anyone know if microclots can be detected with this test?
    Back in 2020, I remember the LC community saying that chest xrays needed Xenon gas to show changes.

  • @honorburza9110
    @honorburza9110 2 ปีที่แล้ว +1

    Great interviews and important research

  • @andreasrylander
    @andreasrylander 2 ปีที่แล้ว +4

    Any non-prescription drugs that might help with the endothelium? Perhaps aspirin and such?

    • @RUNDMC1
      @RUNDMC1  2 ปีที่แล้ว +4

      Yes - and enzymes might help too. We talk about nattokinase and serrapeptase in an upcoming film

    • @Jennifer-gr7hn
      @Jennifer-gr7hn 2 ปีที่แล้ว +1

      Until you have an allergy to aspirin! I am doing serrapeptase....this is quite a thing....platelets keep going up, so do antibodies.

  • @Asteroid_Editz
    @Asteroid_Editz 2 ปีที่แล้ว +13

    We, long covid sufferers cannot thank you enough, Gez 👏👏👏

    • @RUNDMC1
      @RUNDMC1  2 ปีที่แล้ว

      Thank you Isabel!

  • @BJ-bc7sl
    @BJ-bc7sl ปีที่แล้ว

    Where can one go for treatment using this method in the US?

  • @isadorasegura9314
    @isadorasegura9314 2 ปีที่แล้ว +1

    I have your book and your work is amazing! thank you from the bottom of my heart. Wondering if you have come across many long haulers who are on blood thinners and Antiplatelets together to aid with the micro-clots. I only got prescribed apixaban for 7 months and as I became anemic the doctor has removed them. Any advice would be very recommended! Keep being great at your what you are doing and thanks for all your help. You look very healthy too - wondering if you have done any treatments with blood thinners and antiplatelets hehe

    • @RUNDMC1
      @RUNDMC1  2 ปีที่แล้ว

      Hi Isadora - Dr Laubscher is going to talk about exactly this in the next film!

  • @sloth6247
    @sloth6247 2 ปีที่แล้ว +5

    I think the fibrinolytic and pyrolytic enzymes and aspirin saved my life at my worse. I came across this info after I heard Dr. Khan talking about the micro-clots on TH-cam back in 2021, maybe here. My brain is Swiss cheese right now…again thank you so much. Excellent reporting.❤️‍🩹

    • @eugeniebreida
      @eugeniebreida 2 ปีที่แล้ว

      Hi there… Would you mind please divulging which of the enzymes you found most helpful? The more precise in brand, dosage etc. tomorrow I may be able to ascertain what I should do

    • @sloth6247
      @sloth6247 2 ปีที่แล้ว +1

      @@eugeniebreida I used enzymedica nattokinase and seirrapaptase. I also used something called systemic enzymes, it was a store brand, all I remember is that it had some digestive enzymes and bromelain and papain. I was told by the health food guy to take them in an empty stomach and 1 hour or 3 hours before eating. I can’t recommended dosing because I’m sensitive and have to take small doses of medications always. I would say start small and increase as tolerated. I did faint from too much aspirin so be careful with blood thinners. Best of luck. I can’t wait for the next video, I’m going to do a second round.

  • @linsleycharlton6100
    @linsleycharlton6100 2 ปีที่แล้ว +2

    Really interesting! I have bought your book but haven't yet had the energy to read it. Is it worth me trying to self treat? Im thinking aspirin, high antioxidant foods? I definitely think there is something interfering with ATP as I notice when I get fatigued that my quads start to cramp as if i was accumulating lactic acid, and I get very breathless when that happens. Thank you once again for the easy to digest information

    • @RUNDMC1
      @RUNDMC1  2 ปีที่แล้ว +1

      Yes - absolutely. Most long haulers have to! Also watch my videos on metabolism and MCAS - useful tips there re niacin and antihistamines.

    • @linsleycharlton6100
      @linsleycharlton6100 2 ปีที่แล้ว

      Thank you so much for replying. Very much appreciated!

    • @user-fd1qb7ml2j
      @user-fd1qb7ml2j 2 ปีที่แล้ว

      I wanted to ask you if you get real weak in legs and arms for weeks. I had covid last year and only had heart racing and fatigue. It lasted for a long time I did get better and have been pretty good for about 5 months and now I have the horrible fatigue again and had to get of BP meds as they were lowering my BP too much. I am suffering from weak legs and arms , I have to sit alot and can't get anything done over last 2 weeks. When I looked st my old notes from months ago I saw the same patter of weak legs and arms and could not do anything with out feeling luke I was gonna black out or collapse. Been to hospital many times and they say ally tests come back normal. I am so upset I am experiencing the fatigue again as its scary you feel like you are dying. I saw a neurologist and he said its not neurological and that is my long covid and the BP pills and that I should stop taking g them. If I start taking aspirin and my antihistamines again do yiu think I may feel better I dont know what to do. Please help!

  • @Anamaria-ew8lh
    @Anamaria-ew8lh 2 ปีที่แล้ว +4

    I recently had a relapse, or got covid again, and my heart just hurts... I can't do much of activities... and this chest pain is scarring.

    • @Anamaria-ew8lh
      @Anamaria-ew8lh 2 ปีที่แล้ว +2

      Scarry

    • @dalphan819
      @dalphan819 2 ปีที่แล้ว +3

      yup I've had that :( it is scary

    • @biquettesauvage1
      @biquettesauvage1 2 ปีที่แล้ว +1

      Chest pain Is onee of the worst. try to ask tour doctor of It night be cosoco deitis, It comes often After lunga infection from the caughing

    • @alananives4060
      @alananives4060 2 ปีที่แล้ว +1

      same for me. I had it from the beginning of the infection 2021, and then intermittent, now intensifying again. My cardiologist couldn't find anything, I was checked 3 times. Probably an MRI could give more information.

    • @Anamaria-ew8lh
      @Anamaria-ew8lh 2 ปีที่แล้ว

      @@alananives4060 if the RMI shows something, please, let us know! Thank you for responding!

  • @anthonyminniti17
    @anthonyminniti17 2 ปีที่แล้ว +1

    Hey Gez, if these clots are in other diseases(even if long haulers have more of them) Wouldn’t they be a product of an underlying cause and not the cause of symptoms?

    • @RUNDMC1
      @RUNDMC1  2 ปีที่แล้ว

      Product of hyperactivated platelets and endotheliitis

  • @dianecarubia1099
    @dianecarubia1099 2 ปีที่แล้ว +1

    i think there is a trial going on at the moment for AXA1125 for mitochondria

    • @RUNDMC1
      @RUNDMC1  2 ปีที่แล้ว +1

      There is!

  • @ieronimbosh5233
    @ieronimbosh5233 2 ปีที่แล้ว +1

    thanks you very much for your videos

  • @Bella-vr4mt
    @Bella-vr4mt 2 ปีที่แล้ว +2

    How do we treat microclots??? If I tell my Primary Care doctor this, I assume she would do a blood test to see any clotting.. then how will she treat it?
    My PCP and another doctor told me I HAVE Long Covid. So that at least has been determined.

    • @RUNDMC1
      @RUNDMC1  2 ปีที่แล้ว +1

      We talk about testing in the previous episode! Treatments in the next.

    • @Jennifer-gr7hn
      @Jennifer-gr7hn 2 ปีที่แล้ว

      If you have to tell your doctor what to order and ask? LEAVE them. That is their job and they are getting paid for it. Integrity. Get out the mainstream

  • @janeworroll4770
    @janeworroll4770 2 ปีที่แล้ว +1

    Time does seem to help with healing ( maybe not totally but it does help) given this can the body adjust and rid itself of micro clots and get back to more equilibrium??

    • @RUNDMC1
      @RUNDMC1  2 ปีที่แล้ว +2

      People are recovering, so it would seem so :)

    • @janeworroll4770
      @janeworroll4770 2 ปีที่แล้ว

      @@RUNDMC1 I hope so ! 🌸

  • @traiandanciu8139
    @traiandanciu8139 2 ปีที่แล้ว

    Erytrocyte aggregation like coin rolls can be seen,If a drop of fresh blood from finger are put on a cold glass blade,at some patients after SARS COV2 infection.
    Macroscopic apparently agglutinate ,but they agregate at low temperature.
    Did Dextran40 prevent that ?
    Did hidroxichlorchine prevent that?

  • @deethompson3592
    @deethompson3592 2 ปีที่แล้ว +5

    I have to say alot of this is hurting my covid brain 🤭That said I'm truly grateful for all that you do on behalf of us Long haulers - Thank You 🙏

    • @RUNDMC1
      @RUNDMC1  2 ปีที่แล้ว +2

      Thank you Dee!

  • @pauldavid167
    @pauldavid167 2 ปีที่แล้ว +1

    Just a quickie for those with LC high BP. I’m sick as a dog with LC but incredibly cured high BP in 3 days. Mine was 170/120 and resting 154/110. Scary stuff. I have tried everything then BOOM. Twice a day with food. Two raw cloves of garlic chopped (leave 10 minutes) on a spoon, chase with water. Now resting after 3/4 days! 120/83

    • @marky5493
      @marky5493 2 ปีที่แล้ว +1

      I would say it's the Sulphur in the garlic that's the trick, I found I had super low glutathione levels, so my body had been depleted of this anti oxidant which means you end up with runaway inflammation.
      If your bodies liver can't absorb sulfur effectively for whatever reason you want be able to make that compound and u will suffer.
      I turned myself around in days by doing iv glutathione, NOT oral supplemental.
      Was in the dog box of health for nearly 2 years

    • @wendylorimer5663
      @wendylorimer5663 2 ปีที่แล้ว

      @@marky5493 Hi again 😀 that will be why the NAC works for me, the body uses it to make the glutathione. Plus I still claim that eating loads of garlic kept me alive through the worst of the Covid!

    • @marky5493
      @marky5493 2 ปีที่แล้ว +1

      @@wendylorimer5663 absolutely agree, but sometimes the little pathways that make what the body needs are hijacked and become less efficient or downright stopped. The body has many different buffers to counter this but if you max them out too( as you age so you will) then something gotta give.
      someone might be eating all the Sulphur possible but their liver may not be able to use a process to turn that into glutathione that the body so desperately needs. sometimes its just better to give the body the end result and let the body work in reverse and create NAC as a spin off afterwards.
      Good health is not a static point, its a band of comfort between buffers of too much and too little . When you young its wide and narrows as you age.
      But yeah! garlic is the stuff!!!

    • @pauldavid167
      @pauldavid167 ปีที่แล้ว +1

      @@marky5493 Great information Wendy thank you 🙏

  • @KapowskiGG
    @KapowskiGG 2 ปีที่แล้ว

    Hi Gez! Why didn't you include Resveratrol in your book? Was CoQ10 better for NAD?

  • @roydecaestecker9375
    @roydecaestecker9375 ปีที่แล้ว

    Ok, where can I get diagnosed in Belgium? Is there a possibility you can connect me to Anne-Marie van Elsacker (microbioloog in Cetre)?

  • @Jennifer-gr7hn
    @Jennifer-gr7hn 2 ปีที่แล้ว +1

    Yeah, my platelets more than doubled since my severe infection in march 2020 - severe yet no medical help AT all. It was scary, horrid and I'll never be the same. I'm a nurse of 20+ years and to leave some one with new onset circulatory problems that were obvious to me and neglected and pushed aside from 12 doctors in the system. We knew...we were just too focused on getting a "shot" put out there...which is causing the same reaction!

    • @larrylaye9276
      @larrylaye9276 2 ปีที่แล้ว

      Medical help is not the answer
      Fasting is
      Plant based diet 100% one meal a day

    • @LD-yq7cl
      @LD-yq7cl 2 ปีที่แล้ว

      why not consider blood letting ?

  • @SupremeODMG
    @SupremeODMG 2 ปีที่แล้ว

    I have the bad chest pains and palpatations still. I wish I knew what drug refer to at 9:50

    • @becomingapegazebracorn
      @becomingapegazebracorn 2 ปีที่แล้ว +1

      My guess is soludexide after a Google of "Tunisian study endothelium"

    • @flagmichael
      @flagmichael 2 ปีที่แล้ว +1

      I tried googling things that sounded like the one mentioned but without success. When I googled Tunisia endothelial study I got a lot of hits mentioning Sulodexide ("a mixture of heparin and dermatan"). From there the trail spreads a lot and gets cold.

    • @SupremeODMG
      @SupremeODMG 2 ปีที่แล้ว +1

      I managed to find the study it was sulodexide. But not sure how good the data was after reading.

  • @QwinnieLu56
    @QwinnieLu56 2 ปีที่แล้ว +1

    Have there been trials on BC007?

    • @RUNDMC1
      @RUNDMC1  2 ปีที่แล้ว

      Not yet

  • @victorianalin5885
    @victorianalin5885 2 ปีที่แล้ว +1

    Can anyone recommend a brand of Nattokinase please?

    • @alananives4060
      @alananives4060 2 ปีที่แล้ว +1

      Dr. Best 2000 Units its coated.

  • @Thefroggang101
    @Thefroggang101 2 ปีที่แล้ว +2

    Hello!
    Thank you for this amazing video. I'm suffering really bad from post covid symptoms 😢 I got covid in January- I've developed a long list of symptoms that have drastically changed my life for the worst....
    I am unvaxed...
    No one is doing proper testing, or taking me seriously. I don't know eat to do..
    I suspect I have microclots and possibly viral myocarditis

    • @larrylaye9276
      @larrylaye9276 2 ปีที่แล้ว

      Fasting and plant based your welcome. Zero meat protein zero refined sugar

    • @Thefroggang101
      @Thefroggang101 2 ปีที่แล้ว

      @@larrylaye9276 I've always been plant based and always do IF usually 18:6

    • @venuselectrificata
      @venuselectrificata ปีที่แล้ว

      What are your symptoms? I’ve also had covid twice and haven’t felt the same since. Brain fog, tiredness, high blood pressure, anxiety is thru the roof…

  • @marky5493
    @marky5493 2 ปีที่แล้ว

    Thats great news about the progress going forward!. the medication Sulodexide is not available to people in South Africa only Europe:( ( its OTC by the way) Iwas really keen to try it out after reading that study. How does one get it ?

    • @RUNDMC1
      @RUNDMC1  2 ปีที่แล้ว

      I think it’s quite hard to get hold of!

    • @marky5493
      @marky5493 2 ปีที่แล้ว

      @@RUNDMC1 I've found some in Kazakhstan of all places, I have a friend bringing it back:)hooefully it does something good!

  • @mathieusynnott8915
    @mathieusynnott8915 2 ปีที่แล้ว +2

    Im loosing my fight. Im infected since 3 month. Symptoms started 22 of september started with heart palpitation, then turned into PEM leveling heavy stuff, gone thru hospital 13 times saying i was 100% healthy. Now im in bed 22/24 i only eat, shit and drink. My girlfriend give me bath. I cant stand up, i can't walk. My PEM is never ending. I cannot fugure out how i can do this for 60yrs to come.

    • @carolenmarch7445
      @carolenmarch7445 2 ปีที่แล้ว +3

      Start with low histamine diet , 600mg NAC daily , 30mg zinc picolinate , 400mg quercetin, 50mg niacinamide( go up to 100mg slowly) . All in Gez 's Long Covid Handbook , this will start to bring relief , as others have . You Will slowly get better , don't lose hope.

    • @johntruxal432
      @johntruxal432 2 ปีที่แล้ว +3

      I'm 7 months in and can't stand/sit on my own the entire time. Flccc long covid info is free and the h1 , h2 blockers plus all the vitamins. My pcp prescribed ivermectin but no pharmacy would fill the script , resorted to online pharmacy.
      For me 24 mg ivermectin for 20 days. Overall inflamation was reduced , flexability returned and walking with a walker. I am still down 50 lbs but no longer losing weight. Eventually worked myself up to doing arm/shoulder excercises while holding a bottle of water , still difficult toraise arms to shoulder height. Best i'm hoping for is to sit/stand on my own by next 3-5 months. Good luck and i devoutly hope you have family/friends to help you survive. I'm 54 yo and used to work 50/60 hr weeks until i got sick but only surviving with massive help near 24hrs a day. 👍

    • @Jennifer-gr7hn
      @Jennifer-gr7hn 2 ปีที่แล้ว

      Almost three years here...but improving with IV ozone, HBOT, etc....Dr Bruce Patterson's protocol. It's expensive though and I'm broke. At least you have a girlfriend to help you.

    • @IThinkICare
      @IThinkICare 2 ปีที่แล้ว +1

      It is life changing and you have hard time accept it. No surprise. One day at the time. You have help, that is great! They are working and making headways now so not as hopeless as it used to be. Take the little good each day brings and let that be enough. Stress will only make things worse.

    • @carolenmarch7445
      @carolenmarch7445 2 ปีที่แล้ว

      This is a typical response for some patients, the cluster of symptoms and utter feelings of hopelessness as medics at Emergency centres see patients but don't know what they are dealing with., run the standard tests which to the dismay of patients come back as 100% fine. But you only find out what you test for . If Emergency had the knowledge and capacity to test for : micro clots , cellular oxygen levels , a complete bloods with cytokine levels they'd see that things are outside normal reference ranges . The research and education that Gez digs up , while battling with his own illness pathway and recovery ( and he has improved over the last 2.5 years, so have others , some have fully recovered from where you are to full recovery in less time, so have hope ) will help you navigate a pathway to your own recovery. Low histamine diet , supplement stack and listening in to Suzie Bolt's Long Covid yoga recovery programme from your bed , will help heal your soul , which in turn will open the pathway to heal your body successfully . Your girlfriend is amazing to be standing by you in this. Many do not have this emotional support . Loving kindness such as this helps heal , too. You will recover, Mathieu. 😊

  • @willscarlet9823
    @willscarlet9823 2 ปีที่แล้ว +1

    2 weeks later still taking aspirin, added b3. Wow 👌 seriously what is going on, I've now added NAC, holding off nattokinase off for now as so far I'm flying , best all round I have been in 2 years 😀 no crash no relapse , my mood my social interaction has improved, it may be a new me , a changed me no doubt but I'm liking this so far. I'm not kidding myself that it's cured but I'll take this right now absolutely huge thanks for this research 🙏

    • @RUNDMC1
      @RUNDMC1  2 ปีที่แล้ว

      Hope you sustain the improvements Will - don’t rush back to doing too much!

    • @willscarlet9823
      @willscarlet9823 2 ปีที่แล้ว

      No its great I think I've found my pace and level with the cycling and general running around, sticking with it and then we'll see thanks again.

    • @RUNDMC1
      @RUNDMC1  2 ปีที่แล้ว

      @@willscarlet9823 good luck!

    • @andreahunzikerakasarahconn3233
      @andreahunzikerakasarahconn3233 ปีที่แล้ว

      What all did you take? When did you have the vid? How long did you have lc?

    • @ChristyCollins
      @ChristyCollins ปีที่แล้ว

      @@willscarlet9823 How are you doing now??

  • @ryccoh
    @ryccoh 2 ปีที่แล้ว

    I'm sorry what was the litis word that was mentioned repeatedly?

    • @franhinds
      @franhinds 2 ปีที่แล้ว

      Endotheliitis

  • @willscarlet9823
    @willscarlet9823 ปีที่แล้ว

    Sorry me again, interesting followup, I started to head onto that spiral downwards this week, felt sick depressed, my coordination was suffering the usual suspects for a crash , couldn't even speak to anyone at work for 2 days, in bed at 7 every night 😢 scratched my head and then I realized what had changed...I had forgotten to take my aspirin for a few days, took one yesterday am and one at work late afternoon...bam straight back mood lifted energy attitude everything surged. I need to be more steadfast taking these, but do we know anymore on the science, had anyone else had results like this?

    • @RUNDMC1
      @RUNDMC1  ปีที่แล้ว

      This is very dramatic but it does suggest your blood needed some help!

  • @David-ee1pi
    @David-ee1pi 2 ปีที่แล้ว +2

    There are a bunch of accurate biomarkers, notably a panel that checks for endothelial damage and repair (98% LC diagnostic accuracy).
    Published, statistically significant, peer reviewed and ignored!
    Suggestion for researchers and clinicians: use these to confirm the dx before admitting to a trial.
    Nice vids BTW, very professional

    • @eugeniebreida
      @eugeniebreida 2 ปีที่แล้ว +1

      David - may I have the specifics as to this endothelial panel, what’s in it?? All blood/plasma labs? Where does one access it (have a doc ready to order it). Thanks!

    • @RUNDMC1
      @RUNDMC1  2 ปีที่แล้ว

      Are you referring to Bruce Patterson’s cytokine panel?

    • @David-ee1pi
      @David-ee1pi 2 ปีที่แล้ว

      @@RUNDMC1
      No, it's a panel from a Canadian study. Can't post a link to the study here! Will reply via twitter.

  • @LD-yq7cl
    @LD-yq7cl 2 ปีที่แล้ว

    could nattokinase not help thing those microclots?

    • @RUNDMC1
      @RUNDMC1  2 ปีที่แล้ว

      See the final film in the series!

  • @annepalacios1303
    @annepalacios1303 ปีที่แล้ว

    I am a marcher 2020 anyway three year's into COVID SARS TWO I had a blood clot in my knee two days later my oxygen was as 95 96 97 it hasn't been that in three years Ive been on 3 oxygen until my blood clot it's three weeks in and my numbers are going down again. It definitely has something with blood. I thought you would or could be interested. Id love to be a clinical patient .

  • @stephaniewilson3955
    @stephaniewilson3955 2 ปีที่แล้ว

    I would be interested in the book as an e-book but I never buy from Amazon. I will just have to go through the videos, it seems.

    • @RUNDMC1
      @RUNDMC1  2 ปีที่แล้ว

      Have a look on the Waterstones website!

  • @victoriahouse9969
    @victoriahouse9969 2 ปีที่แล้ว +1

    Incontinence and Costochondritis - Gez I've checked your book. Both seem to be new symptoms for me after 3rd covid. They ain't mentioned 😆

    • @victoriahouse9969
      @victoriahouse9969 2 ปีที่แล้ว

      Must add them to 2nd Edition

    • @victoriahouse9969
      @victoriahouse9969 2 ปีที่แล้ว

      My chest pain has been put down to costochodritis. Via Doctor I spoke to last week. Awaiting CT scan to check heart for any further changes.

    • @RUNDMC1
      @RUNDMC1  2 ปีที่แล้ว +1

      I don’t list all 208 symptoms unfortunately! But yes I have heard of both :(

    • @victoriahouse9969
      @victoriahouse9969 2 ปีที่แล้ว

      I'm wondering if I work through all 230 symptoms with then Long Covid leave me alone 😆 . So far I've had over 70+ in last 32 months. Do I win a prize at the end of this?

  • @roonbooks1418
    @roonbooks1418 2 ปีที่แล้ว

    Frick...after watching this, it's going to be years before any of us get any help...and I am severe!!!

  • @rickjondo1343
    @rickjondo1343 2 ปีที่แล้ว +3

    So was Dr Bruce Patterson correct all along? Endothelial damage was key. So should Maraviroc be on clinical trial then? Sheesh 🙄

    • @biquettesauvage1
      @biquettesauvage1 2 ปีที่แล้ว +1

      It should but the world takes its time🙄

    • @alexandrecouture2462
      @alexandrecouture2462 2 ปีที่แล้ว +1

      Lol if Bruce Patterson's work was right, he would have published a study by now, to show the good results. Where are the people his treatment cured?

    • @biquettesauvage1
      @biquettesauvage1 2 ปีที่แล้ว +1

      @@alexandrecouture2462 no idea, i Wish i lieved in the states, at least there are trying trials, here in Italy doctors never even Heard about microclotths apart from Rome, where i Wish to go but frankly I don't know how, due to my 2 infection in july, where things got back to black again. In Rome at the Gemelli hospital they use and exame to find out microclotths, It Is called spect. Scintigrafia polmonare. So in some places they do advance, bit then the results are not diffuse or shared.

    • @IThinkICare
      @IThinkICare 2 ปีที่แล้ว

      wasn't he about the cytokine storm ?

  • @legoguy5944
    @legoguy5944 ปีที่แล้ว

    I hope you read this. Is it rare to have long covid? Or is it an inevitability if you've received two shots?

    • @RUNDMC1
      @RUNDMC1  ปีที่แล้ว +1

      Very, very little to do with the vaccine. Vaccination actually halves your risk of developing LC from a subsequent infection

    • @PowerRobMusic
      @PowerRobMusic ปีที่แล้ว

      ​@@RUNDMC1vaccines can also help a lot of people recover from LC

    • @PowerRobMusic
      @PowerRobMusic ปีที่แล้ว

      ​@@noway3616why are you hiding your face?

  • @maartenvergouwen6584
    @maartenvergouwen6584 2 ปีที่แล้ว

    I read about imatinib: "many patients had fluid in the lungs due to leaking blood vessels. We have therefore treated 400 patients with COVID-19 and oxygen demand in hospital with imatinib. Half of the patients received imatinib, the other half received a placebo. We saw no improvement in the oxygen demand of the patients, but a reduction in the number of deaths and a shorter intensive care (IC) admission. This is important because it can reduce the pressure on the ICs in the Netherlands."

    • @LD-yq7cl
      @LD-yq7cl 2 ปีที่แล้ว

      that seems a CANCER medication... for covid???

  • @BedboundME
    @BedboundME 2 ปีที่แล้ว

    PwME and people with LC seems to have post exertional malaise that is identical in appearance, duration and potential for harm through cumulative effects. Yet the small ME/CFS cohort studied seemed to have much less Microclots, although still abnormal levels. As has been suggested, this might be due to the changes that takes place over time in the PVI sick body. But if MSc were the driver of PEM and explained the unusual characteristics of post exertional malaise (its not seen in this way in other illness , despite some adoption of the term now its being used more in the media with LC, they might have immediate, more brief or less systemic payback from exertion etc) surely those with the worse MCs in the early years of PVI would be getting worse post exertional malaise than later stage ME - which isn’t the case.

    • @RUNDMC1
      @RUNDMC1  2 ปีที่แล้ว +1

      Agree - there are still some big remaining questions to answer here!

  • @Bernard-ux2eb
    @Bernard-ux2eb 2 ปีที่แล้ว +2

    Post viral M.E/CFS. It's not uncommon. Brother developed it after the flu, five years ago.
    It's controlled through a low glycemic index, anti-inflammatory, anti-oxidative diet and supplements. Light exercise and low stress.
    Inflammation and excess cortisol is the problem.

    • @user-zx2mh5wv4z
      @user-zx2mh5wv4z 2 ปีที่แล้ว

      Please don't trivialize our experience. Evidently, you don't have it and that's great. I hope your brother is well. If your suggestions were the answer then there would not be a need for this forum or ongoing research. Many of us have tried all of your suggestions and they offer minimal relief. BTW, I had a post viral illness after mononucleosis and that was nothing compared to this. This has been a career-ending nightmare. I was a front line nurse practitioner in hospital ( insufficient ppe and had to use 2 home made fabric masks. Had one N95 mask per week.) I got it when you still had to jump through hoops to get tested and way before vaccine. I was told to "go home and sleep it off and in 2 weeks you should be fine." No treatment at all since I didn't need hospitalization. So please. A little compassion or get off the forum.

    • @Bernard-ux2eb
      @Bernard-ux2eb 2 ปีที่แล้ว +1

      @@user-zx2mh5wv4z Sorry for state of health, but I'm far from trivialising it and I'm showing compassion here.
      I believe in freedom of speech, so I won't be getting off this forum.
      Hope you get well soon.

    • @IThinkICare
      @IThinkICare 2 ปีที่แล้ว +1

      I don't think those are bad suggestions (careful with the exercise) but many has not been able to recover so there is more to it. Some I heard recovered...good for them.

    • @Bernard-ux2eb
      @Bernard-ux2eb 2 ปีที่แล้ว

      @@IThinkICare Brother has M.E for the last five years after a flu bug.
      He went from near crippled, bed ridden to fully active with the occasional flare up. The NHS was zero help, they sent him to Talk Therapy because, according to them, M.E is a mental health issue.
      Here's how we did it after a fair bit of research.
      Inflammation and cortisol are the triggers that need to be controlled.
      Low glycemic index, anti-inflammatory wholefoods diet + intermittent fasting (aim for One Meal A Day, OMAD), this causes autophagy which clears dead cells and toxins out, supplements, light exercise in fresh air, sunshine and low stress (that's the difficult one).
      Don't take pharmaceuticals like Ibuprofen. Instead, take a teaspoon of turmeric add a pinch of cayenne or black pepper. Add to soya milk or coconut milk (dairy is inflammatory), stir and heat not exceeding 80 Celsius otherwise the anti-inflammatory component, Curcumin, becomes denatured. The pepper increases the bioavailability of the curcumin by some 1,000%. Very strong anti-inflammatory without the toxicity of ibuprofen.
      Also, Magnolia Bark extract. Excellent for cortisol (stress and anxiety) control.
      Supplements for immune system support.
      Quercetin 500mg/day;
      Vitamin D3, 5000iu/day;
      Vitamin C, 1000mg/day;
      Vitamin K2 Mk7, 100mcg/day;
      Omega-3 fish oil, 1000mg/day;
      Zinc 25mg/day;
      NAC 1,600mg/day;
      Black cumin seed oil, 1,000mg/day;
      Turmeric and cayenne pepper as a warm coconut milk drink, twice a day;
      Magnolia Bark extract;
      Don't smoke or drink alcohol.
      It's basically healthy living that works. But it never goes away completely and can suddenly strike. He goes into serious fatigue, hot and cold sweats and serious whole body pain, like the worst hangover ever for a few hours or even a day, takes to his bed. Then, it suddenly goes again and he's fine, literally in minutes. These short flare ups are preceded by stress and/or eating unhealthy food.

  • @brentanoschool
    @brentanoschool ปีที่แล้ว

    have tried Alpha GPC - it has helped with my vision focus -brain fog and fatigue -2 1/2 years of hell Was supplementing earlier with natto - nac -biotin - and serapetase - When I added the alpha gpc it was almost hard to believe the results - steroids did not help - antihitamines helped the swollen sinuses and blood shot weepy eyes

  • @vickiroman189
    @vickiroman189 2 ปีที่แล้ว +1

    Do you compare these symptoms with those who were vaxed?

    • @flagmichael
      @flagmichael 2 ปีที่แล้ว +1

      Speaking for myself, I and my family and friends are all vaxxed. None of us have any of these symptoms.
      I am here because I recognize the enormous problem of Long Covid in individuals and in society. I am also interested in how this research will affect ME/CFS patients of all sorts, including Chronic Active Epstein-Barr Virus Infection, chronic Lyme disease, fibromyalgia, and other related disorders.
      We have to get this figured out. There are only two major outcomes: we learn how to treat (and hopefully prevent) ME/CFS disorders or we accept the unacceptable.

    • @vickiroman189
      @vickiroman189 2 ปีที่แล้ว +1

      @@flagmichael I appreciate you responding.

    • @Turtledove2009
      @Turtledove2009 2 ปีที่แล้ว +1

      Speaking for myself and my immediate family, the adults are all vaxed and we don't have any of those symptoms either but I hope further studies bring to light the concerns that some vaccinated people have with their issues as well. Let us continue to watch and promote these studies.

    • @kellyberry4173
      @kellyberry4173 2 ปีที่แล้ว +1

      Why would it even matter?....Dr's told us the vaccine would help us get over longcovid which was a damn lie

    • @vickiroman189
      @vickiroman189 2 ปีที่แล้ว

      @@kellyberry4173 That was my point, Kelly. Just trying to get more folks to think about correlations.

  • @Peter-mo3pr
    @Peter-mo3pr ปีที่แล้ว

    Is there anywhere in the world, preferably Europe that has the ability to test and treat with the triple therapy? I'd honestly travel anywhere to get answers.

    • @RUNDMC1
      @RUNDMC1  ปีที่แล้ว

      Speak to Dr Jaeger’s clinic in Mulheim (but the waiting list is huge)

    • @Peter-mo3pr
      @Peter-mo3pr ปีที่แล้ว

      @@RUNDMC1 thank you. I have send an email 👍 I take it you would need to visit in person and that bloods can't be drawn and posted?

    • @RUNDMC1
      @RUNDMC1  ปีที่แล้ว +1

      @@Peter-mo3pr yes you need to have blood drawn there

    • @Peter-mo3pr
      @Peter-mo3pr ปีที่แล้ว

      @@RUNDMC1 thank you. One to add to the list.

    • @teddybearroosevelt1847
      @teddybearroosevelt1847 ปีที่แล้ว +1

      You can also pay for the tests out of pocket and pick up the medicines in a country where you don’t need a prescription. Look up the paper Resa Pretorius and her coauthors wrote and you can find all the details on how to go about doing this triple therapy thingy.

  • @nandininandini9274
    @nandininandini9274 2 ปีที่แล้ว +2

    I am suffering from long COVID... meanwhile I have taken the 1st dose of Moderna ...but not feeling well.....should I go for the 2nd dose? Plz someone help with suggestions!!🙏🙏

    • @RUNDMC1
      @RUNDMC1  2 ปีที่แล้ว +1

      I made a video on this - have a look on my page

    • @victoriahouse9969
      @victoriahouse9969 2 ปีที่แล้ว +1

      Tell your Doctor if you've had some reaction to that vaccine. There is other options

    • @Jennifer-gr7hn
      @Jennifer-gr7hn 2 ปีที่แล้ว +1

      I'd day the following as some one with severe oovid march 2020, severe neglect, severe malpractice, and the reaction tot he infection will be the reaction to the injection ......unless, you get the placebo but how will you know you will get that? ...I'd say, out of care...NO.

    • @nandininandini9274
      @nandininandini9274 2 ปีที่แล้ว

      @@RUNDMC1 can u plz give me the link of the particular vdo ?

  • @annapetursdottir5326
    @annapetursdottir5326 2 ปีที่แล้ว +4

    Thank you so much for all your efforts Gez! And so many thanks to all the great work the scientists are doing! ❤‍🩹

    • @RUNDMC1
      @RUNDMC1  2 ปีที่แล้ว +2

      Thanks Anna!

  • @anontablet6304
    @anontablet6304 2 ปีที่แล้ว

    Dr Martin L. Pall states: "I propose here a novel hypothesis of CFS in which either viral or bacterial infection induces one or more cytokines, IL-1beta IL-6, TNF-alpha and IFN-gamma. These induce nitric oxide synthase (iNOS), leading to increased nitric oxide levels. Nitric oxide, in turn, reacts with superoxide radicals to generate the potent oxidant peroxynitrite. Multiple amplification and positive feedback mechanisms are proposed by which once peroxynitrite levels are elevated, they tend to be sustained at a high level."[1]

  • @rSOAPY
    @rSOAPY 2 ปีที่แล้ว +1

    Its been two years. I have to quit my gaming channel. I cant sit in a chair and maintain proper blood pressure anymore. Im scared for my life

  • @JJs2121
    @JJs2121 2 ปีที่แล้ว

    the micro clots caused by the covd cool aid jabby

  • @robinhood4640
    @robinhood4640 2 ปีที่แล้ว +2

    Air pollution = micro clotting.

  • @IThinkICare
    @IThinkICare 2 ปีที่แล้ว

    X cause Y doesn't help people like me who has CFS for 15 years. What caused X ? Reason for the clotting?! Diagnoses is what we have been waiting for .... ever.

  • @mathieusynnott8915
    @mathieusynnott8915 ปีที่แล้ว

    The more i read about LC and EMCFS PEM the less i get the difference between them.

    • @teddybearroosevelt1847
      @teddybearroosevelt1847 ปีที่แล้ว +1

      It may just be the same in a subset of patients, but there are also plenty of long haulers who recover after a few months or people who have relatively minor issues like being unable to smell or taste or say painful toes (and just that)

  • @jameskringlee8974
    @jameskringlee8974 2 ปีที่แล้ว +3

    NAME THE DRUGS FOR GOD'S SAKE! do not "pussy foot" around and provide a link for the Tunisian study when you refer to it.
    That is the professional way.

    • @RUNDMC1
      @RUNDMC1  2 ปีที่แล้ว +5

      Next film will address the treatment side of things directly. Out on Thursday.
      Here’s the link:
      www.ncbi.nlm.nih.gov/pmc/articles/PMC9133483/
      Pretty easy to find via Google rather than just complaining on here 🤷‍♂️

    • @jameskringlee8974
      @jameskringlee8974 2 ปีที่แล้ว

      @@RUNDMC1 Thank You

    • @teddybearroosevelt1847
      @teddybearroosevelt1847 2 ปีที่แล้ว +6

      The way you’re expressing yourself doesn’t quite show the courtesy that you seem to expect from Gez. I’m surprised to see he reacted as kindly as he did

    • @jameskringlee8974
      @jameskringlee8974 2 ปีที่แล้ว +2

      @@teddybearroosevelt1847 Yes, I should have started with Please.. I understand they are trying to help.

    • @flagmichael
      @flagmichael 2 ปีที่แล้ว +5

      @@teddybearroosevelt1847 I agree about courtesy but I cut desperate people some slack. I can't help but admire Gez's poise and upbeat approach, knowing he has been fighting this beast for years.

  • @alexandrecouture2462
    @alexandrecouture2462 2 ปีที่แล้ว +1

    This lady clearly doesn't have long covid. She wants it to take the most time possible and get lots of $$$ from the gov to research while people suffer. That is not okay at all.

    • @RUNDMC1
      @RUNDMC1  2 ปีที่แล้ว +3

      Not quite sure who you’re referring to here?! Prof Pretorius never claimed to have LC, but might just have made the biggest breakthrough to understanding what’s causing it?!

    • @alexandrecouture2462
      @alexandrecouture2462 2 ปีที่แล้ว +2

      @@RUNDMC1 I'm not claiming she has long covid. My point is that these people are far from being in any hurry to find a solution, because it does not affect their own life.

    • @asadik76
      @asadik76 2 ปีที่แล้ว +5

      She’s done more than most to find a solution and you say she is in no hurry and only in it for the money? Do you even know the hours she works for free analysing the blood of longhaulers who travel from all over the world to be treated by Dr Laubscher? She’s an absolute hero.

    • @ryanmcilroy7462
      @ryanmcilroy7462 2 ปีที่แล้ว

      @@asadik76 👍👏👏👏

    • @patriciabryant8892
      @patriciabryant8892 2 ปีที่แล้ว

      @@asadik76 Absolutely - and thank you too Asad xx

  • @nomebear
    @nomebear 2 ปีที่แล้ว +3

    During the AIDS pandemic in the early 80's toxic mitochondrial myopathy was observed in patients treated with the drug Zidovudine (AZT). (pubmed.ncbi.nlm.nih.gov/9168161/)
    The symptoms matched many of the symptoms long haul COVID patients are dealing with today.
    Working with AIDS patients, many refused to take AZT, and were treated for MCAS, NAD+ deficiency with diet and supplements that supported mitochondria repair.

    • @teddybearroosevelt1847
      @teddybearroosevelt1847 2 ปีที่แล้ว +1

      What supplements were they taking and what kind of diet did they eat?

    • @Turtledove2009
      @Turtledove2009 2 ปีที่แล้ว

      @@teddybearroosevelt1847 That's a big topic requiring a lot of research into AIDs patients but feel free to delve into that and let us know.

    • @simonruszczak5563
      @simonruszczak5563 2 ปีที่แล้ว

      From the |) £ @ [ |-| ) @ |3.