Prof. James Ironside - Prions: The serial killers that attack the brain

James Ironside is Professor of Clinical Neuropathology at the University of Edinburgh and Director of the MRC Network of UK Brain Banks. Recorded on 4 November 2010 at the Anatomy Lecture Theatre.

[@primordialmarmoreal1748]

Really detailed and well-explained! I'm doing an APA styled college-level research paper about the evolution of prions for my 10th-grade class. Needless to say, your lecture will be cited in-text repeatedly throughout my paper. Thank you for the presentation, Mr. Ironside!

[@rirwin149]

That was exceptional.
I'm doing Prions for a college course, this has been extremely useful and very informative.

[@Bird_cos]

Did it work out for you?

[@AceofDlamonds]

I've seen this man prof. James Ironside on so many CJD and BSE videos and documentaries. Legend.

[@lizichell2]

The Spanish and British smuggled sheep called Merinos which were renowned for their glossy wool and bred them with British sheep to increase the amount of meat on them which inadvertently spread Scrapie.

[@snake525]

when they make a biography on this homie, you KNOW they're casting John Malkovich

[@alexanderplatzberlin3940]

"Creutzfeld-Jakob" disease and "Gerstmann-Straussler-Scheinker" disease ... okay, that is really not easy for an non-native German speaker. It´s even a tongue-breaker to us.

[@lucianaromulus1408]

I'm an English speaking American. German is closely related to English, not that hard. Try pronouncing Russian or Chinese titled diseases 😅

[@jellokatt]

terrific lecture. really horrifying stuff.

[@ValerieFraser-ph3il]

Was in the 5th Dundee BB Company with James (Jimmy, as he was known then). Always a mature and highly intelligent boy. Nice guy.

[@garyz2043]

Very informative and interesting.
Hopefully those beefburgers I ate in the nineties haven't left any prions behind.

[@krisztinakessel6869]

This prof is true asmr:))

[@TheToryRory]

Thanks , hopefully I can talk about this in my Cambridge interview

[@tamannavatsyan3004]

Did you??

[@MsJustice4ever]

I’m a regular blood donor but I wouldn’t take blood from someone else unless it’s life or death. This is why I refused blood transfusion when I was anaemic. They wanted to give me a bag of blood after giving birth, but I opted out, my levels weren’t so bad as to it being emergency and I opted out.

[@lucianaromulus1408]

We should be allowed to donate for ourselves, like we all have personal blood banks. Its a crime we arent allowed to

[@MsJustice4ever]

@@lucianaromulus1408 I agree. But blood has a limited shelf life so to keep it around for emergencies wouldn’t really work. However, they should absolutely allow it for preplanned surgeries and such.

[@lucianaromulus1408]

@MsJustice4ever why couldn't we just routinely donate though ?

[@mdimarco87]

So you are telling me you can't detect this in people other than a brain biopsy?!? that is shocking we need to improve this! What's to say we don't all have some level of prions in the brain? What are some ways the immune system can fight them?

[@wiktoriakos2597]

The thing is nothing can get rid of them, nothing we know today can actually get rid of these disease prions and they are almost undetectable untill the very last years of sufferers life

[@AceofDlamonds]

Prof. Ironside deserves better questions from an informed audience.

[@KeyserTheRedBeard]

awesome upload The University of Edinburgh. I killed that thumbs up on your video. Maintain up the excellent work.

[@addictedtocheese3688]

Thank you for this Video

[@lizichell2]

exceptional!

[@ardybayat2645]

Very pertinent given covid and inoculation risk of same

[@hggryrdchgc]

@@sbraypaynt the mRNA experimental gene therapy aka "vaccine"

[@mdimarco87]

dandelion root

[@johnguetterman676]

My sister has been diagnosed with CJD. 4/2021. We are heartbroken.

[@michelekisly2535]

So sad

[@somneang87time29]

How’s she now?

[@michelles5439]

When was she jabbed?

[@2hetig]

How was she diagnosed?

[@loner8045]

Is she still alive?

[@addictedtocheese3688]

What are the chances of a new wave/breakout of vCJD in the future?
Incubation time in some kuru cases are crazy long, arent they? The Last kuru victim died in 2005 (or 2009 some say) and they say that they stopped eating human meat in the early 1960s. So this would be a time gap of 40+ years.

[@uniquestar7]

Is it possible that perhaps chaperones are somehow involved in both, prion diseases as well as others such as Alzheimer's, seeing as both involve misfolded proteins?

[@AceofDlamonds]

See lectures of Stanley Prusiner.

[@isabellacosta4937]

Very good thank's!

[@imacharginmalazer100]

Please turn on the subtitles while watching this.

[@kimlaw2425]

I know people who owned a steak house and their children died of CJD somehow the parents were carriers How is that?

[@arie725]

Please find a cure

[@mdimarco87]

dandelion root

[@nin3755]

This could save our planet if a human version evened out our population a bit

[@Realitycheck-mqt]

Is this just a form of amyloid disease?

[@wteo340]

Definitely Michael Ironside's long lost brother! Or half-brother..

[@Aythe1]

Nanobots programmed on the 43% betasheet of the prions :D

[@brucey5232]

Boring.

[@alexanderplatzberlin3940]

Interesting!

[@EekItsYouRS]

No one asked

[@Lilacrosepetalleaf]

Yes you are!!