Which Chemical is the Best Disinfectant? (Disinfectant Lore)

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  • เผยแพร่เมื่อ 3 พ.ย. 2023
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    Bleach really exists in your body? Propylene glycol disinfects the air? Apparently. Maybe that means people who vape are sterilizing the room? Fat rips season? Probably not.
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ความคิดเห็น • 684

  • @1234lavaking
    @1234lavaking 7 หลายเดือนก่อน +223

    5:23 my mom always told me “there are two categories of cleaners: bleach, and things you don’t mix with bleach.

    • @sydhenderson6753
      @sydhenderson6753 7 หลายเดือนก่อน +12

      If I remember, it features not only in stories about people accidentally producing chlorine, but also phosgene, which apparently has a pleasant smell until you die of asphyxiation by your throat closing.

    • @rexperverziff
      @rexperverziff 6 หลายเดือนก่อน +5

      @@sydhenderson6753what did you die from?
      i don’t know, but at least it smelled good

    • @costlycoffee4234
      @costlycoffee4234 5 หลายเดือนก่อน +6

      @@sydhenderson6753 even worse, its a lightly musty / haybale smell and even if you know that you need to get out phosgene can cause your lungs to fill with fluid hours later

  • @MisterTalkingMachine
    @MisterTalkingMachine 7 หลายเดือนก่อน +142

    My very cold and poorly ventilated dorm room used to get lots of mold on the walls during winter until the day I built an ozone generator with parts from old TV sets, and left it running while I was away to class. The problem pretty much ended there.

    • @jakedill1304
      @jakedill1304 7 หลายเดือนก่อน +27

      Just remember that ozone kills electronics as well.. and other things that you may not want killed that.. well let's say the only living they probably did is have a machine spirit.. so you want to be real careful when you're running it and maybe remove certain items from the room.. especially if you're doing it regularly.. but also God bless it cuz LOL I'm a smoker that's allergic to perfumes.. what I do without it LOL.

    • @zyeborm
      @zyeborm 7 หลายเดือนก่อน +50

      Ozone kills plastics, fabrics, pretty much anything with carbon chains in it over time 😂
      Useful but be careful.

    • @MisterTalkingMachine
      @MisterTalkingMachine 7 หลายเดือนก่อน +26

      Very goog advice, thanks everybody. Usually when I left there'd be no electronics left in the room other than a phone charger.
      The output of the generator declined slowly over time as the electrodes I made started to get covered in corrosion, but it still got me through the remainder of that winter pretty well.

    • @coopergates9680
      @coopergates9680 7 หลายเดือนก่อน +6

      I think nitrogen dioxide should be looked at for these types of applications as well, if it's easier to produce (and doesn't spontaneously decompose in high concentrations).

    • @vaultdweller2511
      @vaultdweller2511 7 หลายเดือนก่อน +6

      @@coopergates9680 Electric arcs will form oxides of nitrogen as well as ozone, using just the N2 and O2 out of the air. This was actually used industrially to produce nitric acid by bubbling the output through water (using massive amounts of power because the yield is low) about a hundred years ago. I once used a neon-sign transformer to produce small quantities of nitric acid this way, before the boyfriend complained too much about the constantly buzzing scary electric arc in the garden shed.

  • @Deritsuku2010
    @Deritsuku2010 7 หลายเดือนก่อน +372

    So a fun fact in case no one else mentioned it: Bleach is used as a last resort method in my local hospital, for example if someone had MRSA. The reason for this is that we don’t want a situation where bacteria becomes resistant to bleach, which, for obvious reasons, would be pretty bad.

    • @KibitoAkuya
      @KibitoAkuya 7 หลายเดือนก่อน +17

      Genuine question, why bleach specifically over any other? Is it because of strength?

    • @coleb2264
      @coleb2264 7 หลายเดือนก่อน +71

      ⁠@@KibitoAkuyaif I had to guess it’s a combination of strength and availability. We don’t want a scenario where some superbug survives bleaching surfaces, because right now bleach is an incredibly effective, incredibly easy to access disinfectant

    • @harrywilliamson7043
      @harrywilliamson7043 7 หลายเดือนก่อน

      ......we have been using basically chlorine bleach to disinfect for water treatment for well over a century and no super bug has appeared yet. Chlorine is such a strong oxidizer it would be difficult for a bug to withstand it. About the only one I know of is Cryptosporism and even there it will eventually die if in contact with chlorine long enough.

    • @Ne1vaan
      @Ne1vaan 7 หลายเดือนก่อน +1

      ​@@coleb2264Additionally chlorinating a person is bad. Less bad than dying, but oxidizers like oxygen and chlorine make carcinogenic shit when you add them to organic compounds. Bleach is a little too deadly (directly or otherwise) for regular use. And a little too good to let bugs evolve resistance to.

    • @jozak78
      @jozak78 7 หลายเดือนก่อน +44

      A hospital I used to work at decided to switch to bleach based disinfection for everything in the hospital. That lasted one year because the bleach destroyed the surfaces of all of the furniture in the hospital.

  • @ShockedCaucasian
    @ShockedCaucasian 7 หลายเดือนก่อน +240

    This was super cool! Its nice to learn actually h o w the disinfectants work rather than just "Kill microbes"

    • @user-yw9mw9hv8o
      @user-yw9mw9hv8o 7 หลายเดือนก่อน +8

      Yes, another big thing is how disinfection =/= sterilisation, as was mentioned with the lack of sporocidal activity of isopropanol for example. Bacterial spores are really tough, all tightly packed and desiccated and coated in thicc layers and shit. If your material isn't sensitive to heat or water you can autoclave it, but in other cases you need stuff like ethyleneoxide. That's why so much sterile material like plastic syringes is often sterilised chemically.

    • @NipkowDisk
      @NipkowDisk 7 หลายเดือนก่อน +1

      I agree. I had no idea why there is usually a mixture of quaternary ammonium compounds in such a disinfectant. I always figured it was for cost savings in production while maintaining efficiency; however, each one described targets different types of organisms. It could be both, though, and perhaps was discovered by accident (not at all unheard of).

  • @diablominero
    @diablominero 7 หลายเดือนก่อน +46

    Chloraseptic works for sore throat better than anything else I've tried. Smells and tastes like evil rotting plastic, but when you're in pain and can't sleep, sometimes evil rotting plastic is tolerable.

    • @SoulDelSol
      @SoulDelSol 7 หลายเดือนก่อน +15

      The green one is minty and red one is cinnamony.

  • @marioster2
    @marioster2 7 หลายเดือนก่อน +633

    It’s 2 minutes into the upload. I better not see anyone talking about how they watched the video that fast

    • @johndeaux8815
      @johndeaux8815 7 หลายเดือนก่อน +88

      Just finished the video ten times and it's a banger💯💯💯💯🔥🔥🔥🔥

    • @Sniperboy5551
      @Sniperboy5551 7 หลายเดือนก่อน +49

      Wow, another great video! Bleach is not a very good mouthwash!

    • @gbabes175
      @gbabes175 7 หลายเดือนก่อน +17

      The video is great prob his best one

    • @kphaxx
      @kphaxx 7 หลายเดือนก่อน +9

      @@Sniperboy5551 Speak for yourself!

    • @squigglycups5666
      @squigglycups5666 7 หลายเดือนก่อน +17

      Thank god, now we need a degreaser tier list

  • @Sniperboy5551
    @Sniperboy5551 7 หลายเดือนก่อน +284

    I love the fact that I fell asleep to the irritant video last night, now I can fall asleep to this one. There’s something soothing about chemistry and this guy’s delivery, I love this channel!

    • @Renoh74
      @Renoh74 7 หลายเดือนก่อน +2

      Haha I also fell asleep while watching last night, woke up kind of irritated for some reason

    • @janneaalto3956
      @janneaalto3956 7 หลายเดือนก่อน +1

      It's the sound of learning XD

    • @RobynDeBank
      @RobynDeBank 7 หลายเดือนก่อน

      Omg same

  • @NipkowDisk
    @NipkowDisk 7 หลายเดือนก่อน +106

    I was hoping to see mercuric chloride in this list... I had a neighbor many years ago who worked for the state Health Department. One day we were talking about disinfectants, and I mentioned mercuric chloride to him. His eyes nearly popped out of his skull. He told me a story where they took a Petri dish full of ultra-nasty stuff and they put in a solution (probably 1:3000 or similar) of mercuric chloride. They examined the dish under a microscope ten minutes later, and NOTHING was alive.

    • @cavalieroutdoors6036
      @cavalieroutdoors6036 7 หลายเดือนก่อน +14

      That sounds like stuff that would erase everything. Possibly to include the user.

    • @NipkowDisk
      @NipkowDisk 7 หลายเดือนก่อน +14

      @@cavalieroutdoors6036 Yep. One to two grams is fatal.

    • @alexlo7708
      @alexlo7708 6 หลายเดือนก่อน

      I think it was just chlorine that kills microbes. Mercury does nothing.

    • @derAtze
      @derAtze 4 หลายเดือนก่อน +4

      Got to be honest, doesn't sound too bad to me. A few shavings of silver probably could have done the same, as well as half of the disinfectants on the list. Its easy enough to disperse a quarter gram in a liter of solution which makes it non lethal by dose, and it seems to be effective. Bleach also is able to destroy its user, it's still sold in basically every convenience store on earth

  • @alfredoprime5495
    @alfredoprime5495 7 หลายเดือนก่อน +118

    According to one of my chemistry profs, because there's no such thing as iso-propane then there can't be such a thing as iso-propanol. He made me change all mention of iso-propanol is a lab report to 2-propanol. Yeah. The reaction you're having now was my reaction too.

    • @justinedward9243
      @justinedward9243 7 หลายเดือนก่อน +45

      Should be Propan-2-ol🤓🤓

    • @frunkchungus
      @frunkchungus 7 หลายเดือนก่อน +36

      Howisheemployedat-ol?

    • @mmmhorsesteaks
      @mmmhorsesteaks 7 หลายเดือนก่อน +30

      Man you get these weirdos sometimes - like "ammonium hydroxide" in stead of just ammonia - because we don't have lewis theory apparently...

    • @fleskenialation
      @fleskenialation 7 หลายเดือนก่อน +1

      ​​@@justinedward9243i think both are fine and convey the same thing. Guess it just depends on who your audience is

    • @zombieregime
      @zombieregime 7 หลายเดือนก่อน +14

      @@mmmhorsesteaks Have you heard about the dangers of dihydrogen monoxide?

  • @AsmodeusMictian
    @AsmodeusMictian 5 หลายเดือนก่อน +21

    "...it's effectively oxygen gas that got into a car accident"
    I laughed way harder than I should have at this.

  • @LemurG
    @LemurG 7 หลายเดือนก่อน +54

    I had a high concentration phenol put on my toes when I got surgery for ingrown nails! My podiatrist explained everything that was happened because chemistry is fun. I got shots that made my toes completely numb so I felt nothing at all. The skin turned completely black and it was really interesting to watch! My toes are pretty much fully healed now

    • @ZMandoness66
      @ZMandoness66 7 หลายเดือนก่อน +11

      I love the mechanisms behind "what and why people use it". I think it might drive my doctors nuts but the innate curiosity is definitely unquenchable.

    • @MrGatlin98
      @MrGatlin98 7 หลายเดือนก่อน +5

      @@MalachiWhite-tw7hl I 've had the same surgery. It's definitely not comfortable but not the worst. The most painful part is if the needle goes "too far" and hits the under-side of the nail; that didn't feel good. The injections are certainly the worst part of the whole ordeal.
      Fun fact, the phenol application didn't work for me, and the nail grew back. I had to have a second surgery.

    • @mem1701movies
      @mem1701movies 7 หลายเดือนก่อน +3

      @@MrGatlin98I tried with an Xacto Knife and pliers to get rid of one to no avail. Went to a podiatrist with no insurance and asked how much the numbing agent was. So I just had him yank out the ingrown toenail without it.

  • @PeperazziTube
    @PeperazziTube 7 หลายเดือนก่อน +20

    I used to work in a turkey egg farm. A mixture of permanganate and methanol (producing formaldehyde gas) was used to disinfect the eggs after collection. Killed bacteria but did not harm the avian foetus.

    • @SoulDelSol
      @SoulDelSol 7 หลายเดือนก่อน +4

      Dinosaur egg farm

  • @FleshWizard69420
    @FleshWizard69420 7 หลายเดือนก่อน +71

    Isopropanol is an excellent disinfectant. Also makes great cryofluid too

  • @mattnichols3555
    @mattnichols3555 7 หลายเดือนก่อน +16

    10:25 hey finally a chemical store I can add! I was gargling with hydrogen peroxide as a kid (had a mouth ulcer iirc) and had two of those small paper cups set out in the bathroom. One I was using with water to rinse the taste out of my mouth and one for hydrogen peroxide. I mistakenly swallowed a small amount of hydrogen peroxide (~10 mL or so) and promptly freaked out. Taste was horrible and tingled/slightly burned going down my throat. Parents called poison control and they said to just drink a bunch of water and monitor for other symptoms. 0/10 do not suggest taking shots of H2O2.

    • @samiraperi467
      @samiraperi467 14 วันที่ผ่านมา +1

      If you drink H2O2, drink H2O too.

  • @me0101001000
    @me0101001000 7 หลายเดือนก่อน +71

    Have you done detergents yet? Because they're a lot more interesting than they get credit for imo, and also I'm itching to share some fun facts about detergents.

    • @revenevan11
      @revenevan11 7 หลายเดือนก่อน +7

      I second this topic suggestion!

    • @Galangxd
      @Galangxd 6 หลายเดือนก่อน

      YES!

    • @ChildrenOfOwls
      @ChildrenOfOwls หลายเดือนก่อน

      I would love that too…. Also feel free to slap some detergent fun facts on me

  • @rhynnoh1991
    @rhynnoh1991 7 หลายเดือนก่อน +23

    I appreciate the cutaways containing more detailed explanations of some of the terminology

  • @robertb6889
    @robertb6889 7 หลายเดือนก่อน +16

    My wife worked in the hospital and they used peroxy-acetic acid formed by a mixture of hydrogen peroxide and acetic acid for sterilizing surfaces.

    • @prankmastereight
      @prankmastereight 7 หลายเดือนก่อน +4

      In my experience it has a habit of bleaching your skin lol

    • @darksu6947
      @darksu6947 7 หลายเดือนก่อน +3

      ​@@prankmastereightIt's ok to be white 😂

    • @robertb6889
      @robertb6889 7 หลายเดือนก่อน +3

      @@prankmastereight didn't do that for her, but it caused massive nasal/sinus irritation for her when using it.

    • @prankmastereight
      @prankmastereight 7 หลายเดือนก่อน

      @@robertb6889 must be real stinky

    • @-r-495
      @-r-495 7 หลายเดือนก่อน +2

      finally someone else from my nick of the woods..!
      Yes, peracetic acid was missing for me too! VHP is effective for surfaces only but Minncare will churn through the worst stuff within a few hours in the right conditions.
      Used in labs too („furry“ science..).

  • @randomuseryt5143
    @randomuseryt5143 7 หลายเดือนก่อน +18

    IPA is effective on de-roaching small articles of electronic equipment by dumping some into a garbage bag and placing the object inside and sealing the bag for 2 or 3 days, would not recommend for anything plastic or with lots of glued on labels and decals

  • @MarekKoshinski
    @MarekKoshinski 7 หลายเดือนก่อน +45

    As someone who’s had Spinal Fusion twice.. Povidone-Iodine 1% is something I’m very used to. I would have to have that poured onto my back every time they changed my bandage. I remember one time they spilt the bottle onto me and I thought it broke open the wound since it looked like blood. 😂

  • @archivethearchives
    @archivethearchives 7 หลายเดือนก่อน +23

    Don’t forget radioactive materials. Radiation is used a lot for sterilization of single use medical equipment apparently. According to the IAEA, 40% of single use medical devices worldwide are sterilized using gamma irradiation. Although I am not sure what exactly is used to produce those rays. 🤓 (yes, I am aware this is probably a misinformed and very annoying comment. Take it with a grain of salt. Great content as always. 👍)

    • @archivethearchives
      @archivethearchives 7 หลายเดือนก่อน +1

      Also I am well aware that mostly recanting my statement does not nullify any reasonable criticisms. And that my comment very blatantly ignores the spirit of this video in bad faith just to be annoying.

    • @aqdrobert
      @aqdrobert 7 หลายเดือนก่อน

      Hulk LOVE gamma rays. SMASH puny bacteria!

    • @derAtze
      @derAtze 4 หลายเดือนก่อน

      Don't feel offended by this, but are you an autist? 😅

  • @FirstLast-oe2jm
    @FirstLast-oe2jm 7 หลายเดือนก่อน +12

    I've always been curious why there's so many disinfectants in use, some of them make sense but there's just so many! Great content as always!

  • @whynotjustmyusername
    @whynotjustmyusername 7 หลายเดือนก่อน +2

    Doctor here with some more or less educated corrections:
    0:13 The effective agent in most skin disinfectants is isopropanol and/or ethanol though. Yes, some products also contain chlorhexidine or octenidine, but that is usually put there to have a continuous antimicrobial effect even after the initial disinfections, which is useful for catheters etc. that pierce the skin and are to remain in place for a longer period. The isopropanol is doing the main bug killing work though.
    There are also some products where the chlorhexidine or octenidine are the main effective agent, but those are rarely used for preoperative or preinterventional skin disinfection, but mostly for wound care or disinfection of mucosae or genitalia. One case where octenidine is actually used for skin disinfection is before taking a blood sample for alcohol testing, to avoid any potential preanalytical falsifications.
    7:29 Endoscopes are not sterilized but disinfected. Anything that goes into a sterile field, respectively inside a person (the digestive tract is technically just a tube of "outside" going through the body, so in there doesn't count) has to be properly sterilized. That also counts for laparoscopic instruments and optics which are typically autoclaved. In general, the most common sterilisation methods for any sort of medical product are autoclaving, ethylene oxide or radiation. Stuff that gets re-used will typically be autoclaved. AFAIK glutaraldehyde cannot be used for sterilisation, at least under the guidelines of the RKI, the German federal public health office.
    Finally I'm a little sad you didn't include peracetic acid as its own thing (yes, you mentioned it in "bleach", but eh). Peracetic acid actually has a cultural heritage where I'm from, East Germany. East Germany kept huge stockpiles of that stuff to use as disinfectant in case of a biological warfare attack. However since it's so sensitive to... everything and decomposes over time, it cannot be stored for long and had to be constantly produced... and therefore also used. So in East Germany it was used to disinfect just about everything. From antimicrobial soaps, to cleaners to mop floors with to disinfecting livestock bays. Many visitors to East Germany remarked of the characteristic smell of East-German buildings.

  • @alexkaplan6581
    @alexkaplan6581 7 หลายเดือนก่อน +9

    3:25 Speaking of cleaning throats, some people use those sprays as a way to relax muscles in the throat. For what reasons, I shall leave to your imagination.

    • @pellestorck3776
      @pellestorck3776 7 หลายเดือนก่อน

      Where did you pick up that piece of information? Lol

    • @alexkaplan6581
      @alexkaplan6581 7 หลายเดือนก่อน

      @@pellestorck3776 Online friends.

    • @michaelimbesi2314
      @michaelimbesi2314 7 หลายเดือนก่อน

      Good to know, thanks ;)

  • @koukouzee2923
    @koukouzee2923 7 หลายเดือนก่อน +2

    Bro iam crying
    "Prepare your endo for the scopes"

  • @Mike_359
    @Mike_359 7 หลายเดือนก่อน +4

    91% Isopropanol is pretty good as a cleaner though, especially if you put a bit on a qtip to clean small electronics. In this case, the evaporation helps!

  • @jizmoglass4202
    @jizmoglass4202 7 หลายเดือนก่อน +13

    I used to have a cleaning contract with a local Dentist office. We used Parsons Ammonia to wipe down all the dental stations. Fabuloso for the floors. The dentists were clean so we rarely had to use bleach. Maybe in the bathroom that the patrons use. Honestly was one of the best places I ever worked and it was just me and sometimes another guy, for like 2 hours, 5 days a week. Super nice people. Heritage in Dundas/Northfield. Ya. Where Jesse James did his thing at the bank.

  • @GogiRegion
    @GogiRegion 7 หลายเดือนก่อน +2

    Benzalkonium chloride is great for disinfecting when you get an IV or a shot because it doesn't cause that burning sensation the same way as alcohol and other disinfectants. With alcohol, you can wait for all of it to evaporate, but many times nurses and lab techs don't have time to wait that long every needle poke, but if they have benzalkonium chloride, it doesn't matter.

  • @ZergZfTw
    @ZergZfTw 7 หลายเดือนก่อน +10

    I think ozone is my favorite, it oxidizes just about everything. Plus it can be used for the same things potassium permanganate + greensand like getting rid of dissolved iron. I have heard ozone plus UV light can even break down PFAS.

    • @lillian8589
      @lillian8589 7 หลายเดือนก่อน +3

      Also ozone plus hydrogen peroxide = amazing oxidizer. Either way, ozone is hard to beat.

    • @derAtze
      @derAtze 4 หลายเดือนก่อน

      I really fell in love with it since moving into my dormitory. You're allowed to smoke in there (which i knew) but have to paint it in a special 90€ paint when you switch rooms/move out (which i didn't knew). So I smoked a lot of weed, and when wanting to move in a better room being bummed out by the bill. So I refused to buy that paint and do all the walls, so i just bought an O3 generator for literally half the price of the paint which did an even better job as the paint (which basically just coats the wall in a layer of plastic) that my roomate used for his room. I use it quite regularly every few months to make my room fresh again (since I live sleep work in the same room, lets just say smells can accumulate even while being somewhat cleanly) and to disinfect my pet snakes terrarium once in a while to prevent mold from growing and to get rid of ammonia buildup and stuff. It's an amazing piece of technology, it just does so many parts of cleaning on the press of a button and reaches literally everywhere where there is air. Insane stuff

  • @ScatteredParticles
    @ScatteredParticles 7 หลายเดือนก่อน +5

    There's actually UV wavelengths deeper than the typical 254 nm UV-C light from mercury lamps which are completely safe at fluxes capable of sterilizing 90+% of microbes. Photons between 215-235 nm are fully absorbed in the first few micrometers of skin (which are all dead cells) and so can't DNA damage in living tissue. This is true even for your eyes, because they too have a very thin layer of dead cells on the surface.

    • @-r-495
      @-r-495 7 หลายเดือนก่อน +1

      this is not common practice in industry at all.
      currently MH UV sources are the only ones that may be used for some applications.

  • @Rover1309
    @Rover1309 7 หลายเดือนก่อน +4

    Fun fact, chlorine and chlorinating agents are added during water treatment to also bind to reactive cyanide groups.

  • @Sniperboy5551
    @Sniperboy5551 7 หลายเดือนก่อน +6

    Bro really edited My Little Pony on that jar 💀

    • @That_Chemist
      @That_Chemist  7 หลายเดือนก่อน +1

      You already know

  • @danielharrison5731
    @danielharrison5731 4 หลายเดือนก่อน +1

    Surgical technologist here! Here's some more insight into chlorhexidine (CHG) and iodine.
    CHG is used in many surgical scrubs and preps as it not only has a broad spectrum effect that drives quickly, but also builds up on the skin over time with multiple uses. Many patients are given CHG wipes to use at home one to two days before surgery to help build up that film of antimicrobial good stuff. In addition, CHG is frequently found in IV start kits, and is a well used antiseptic right alongside an alcohol swab. For iodine, it will stain a little bit, but that's good because we want to see where exactly we need to still hit with the iodine prep. We would typically use this when someone is allergic to CHG, but you need to be very careful with iodine. If you have an allergy to shrimp or shellfish, you will be allergic to iodine prep It has similar chemical indicators to shellfish. Last thing to be picky, c h g and iodine are both considered antiseptics, but can also be used as disinfectants. This is a legitimate difference, but that's just me nitpicking. This is an awesome video man, very well done

  • @Nexus_545
    @Nexus_545 7 หลายเดือนก่อน +1

    My lab had an over zealous crackdown on health and safety and we replaced all the common lab disinfectants with household cleaners using Benzalkonium Chloride. Since then we've been finding more surviving Salmonella and resistant E.coli from our routine monitoring. Interesting to know there's different chain lengths with different efficacies.
    We also found that it deteriorates our plastic equipment over time but that could be other compounds in the solution I guess.

    • @nibs7252
      @nibs7252 7 หลายเดือนก่อน

      I mean, you can always try dousing everything in Lugol's

  • @NautsuJJR
    @NautsuJJR 7 หลายเดือนก่อน +9

    damn. weve been getting back to back videos and theyre all still really thorough, this is great

    • @shadowpoet4398
      @shadowpoet4398 7 หลายเดือนก่อน

      Leave it to a chemist to be completely thorough. Walter White said it "This is CHEMISTRY! _DEGREES MATTER!!_ Now drain it and start over!"

  • @keisisqrl
    @keisisqrl 7 หลายเดือนก่อน +3

    Quaternary ammonium deserves S tier! If you’ve ever worked back of house towels in a bucket of quat sanitizer are the universal cleaner during service.

    • @That_Chemist
      @That_Chemist  7 หลายเดือนก่อน +2

      They work so well

    • @quincyboyce845
      @quincyboyce845 7 หลายเดือนก่อน

      i need to get a barrel of quat concentrate for my home!!! that stuff is so good for wiping anything and everything food-related away

  • @justapersononhypixel884
    @justapersononhypixel884 7 หลายเดือนก่อน +2

    as a person who accidentally made chlorine gas using bleach in my kitchen, yea listen to this guy don't mix it lol

  • @KarlKarpfen
    @KarlKarpfen 5 หลายเดือนก่อน +2

    By regulation (EU-MDR) for medical device cleaning, disinfection and sterilization, the S-tier would be heat for both disinfection (90-95°C for 5 min) and sterilization (three cycles of 121°C steam and then vacuum),
    the A-tier is ethylene oxide or ozone for sterilization and peracetic acid for disinfection and
    the B-tier would be formaldehyde for sterilization and glutaraldehyde for disinfection.
    The others are rated worse for application on medical devices (in Europe).

  • @christianterrill3503
    @christianterrill3503 7 หลายเดือนก่อน +13

    They use isopropyl alcohol pads for injections, vaccines and IV prep. They are using the stronger stuff for surgery like iodine and clorahexadine

  • @grayski3324
    @grayski3324 7 หลายเดือนก่อน +4

    Woah, this will be so useful for when a ton of strawberry jam is spilled in my attic.

  • @Xiassen
    @Xiassen 7 หลายเดือนก่อน +2

    I love info being described as lore

  • @JonathanAlexanderM
    @JonathanAlexanderM 7 หลายเดือนก่อน +1

    Back when I used to work at cvs our manager would tell us to pour bleach and ammonia within the bags of candy or whatever we had to throw out so that no one could get to em when we threw em out back. You’d tie the bag and then it’d puff up real good. I always thought it was messed up but I didn’t want to lose my job

  • @benbookworm
    @benbookworm 7 หลายเดือนก่อน +3

    Phenol works really well when you have sore throat. It's like (and might be) that initial numbing stuff the dentist gives you before using that big needle of numbing. Cough painlessly!

  • @sashboo1370
    @sashboo1370 7 หลายเดือนก่อน +1

    Very nice video as always! Another video auto played after and I realised your mic quality has really improved!
    One thing I will say though, you didn't mention my favourite disinfectant, singlet oxygen!

  • @Sanchuniathon384
    @Sanchuniathon384 7 หลายเดือนก่อน +1

    I use 29% hydrogen peroxide to bleach animal bones from BBQ, hunting, etc. Last time I used 6 litres of it, it FUMES a LOT. Boy I wish I had a fume hood, but I always do it outside. It takes like a week to turn really nasty bones into fine museum specimens.

  • @satelliteexile2089
    @satelliteexile2089 7 หลายเดือนก่อน +1

    I was just chilling, listening to some chemistry, and then BAM, PONY.

  • @sammyjones8279
    @sammyjones8279 7 หลายเดือนก่อน +1

    Hearing that "this substances kills your own cells" then seeing a picture of a medication I use frequently flashed on screen in the same sentence was definitely an *experience* today 😂

    • @paulm.8660
      @paulm.8660 5 หลายเดือนก่อน

      Really unclear what the criteria are for these tiers. Phenol is too effective at killing things, it kills your own cells too, C-tier. Bleach dissolves human flesh but also produces deadly fumes if mixed with other cleaning chemicals, A-tier. Chlorhexidine is safe to put on your hands, in your mouth, and in your eyes, but makes you go deaf and gives you cancer, S-tier.

  • @Rusty-METAL-J
    @Rusty-METAL-J 7 หลายเดือนก่อน +2

    Hey guy I've seen more than a few of your Chem vids and this is the 1st 1 featuring - well you. Kewl content man. I like the way you show the molecular formulas for the chemicals. Any body can write a chemical formula like H20, but not everyone can draw a molecular formula that looks super nice.

    • @Rusty-METAL-J
      @Rusty-METAL-J 7 หลายเดือนก่อน +1

      Mine have always been d'ed. w/ Isopropyl Alcohol pads.

  • @agentofashcroft
    @agentofashcroft 7 หลายเดือนก่อน +2

    Love to see the mechanism of action of these different disinfectants, which I've found hard to find in one place. I'm a microbiologist and would personally rank these based on their sporicidal activity, since some bacteria and most fungi can form dormant spores which are very resistant to many disinfectants. This is why I'm not a big fan of hand sanitizer since ethanol does nothing to these spores - wash your hands instead!

  • @PyromaniacLVI
    @PyromaniacLVI 7 หลายเดือนก่อน +4

    This video is great!
    I see the effort in the research, its good stuff. (love the mechanism stuff)
    I'd love if you did a tierlist on preservatives. (Isothiazolinones, bronopol, pyrithiones, glycols, organic alcohols etc.) I work in an analytical chemistry lab with these and three's some interesting chemistry with them.
    EDIT: i just watched again and comment up top was covered with benzalkonium chloride.

  • @chantellekirk2993
    @chantellekirk2993 7 หลายเดือนก่อน +1

    In 2018, quaternary ammonium compounds became my kryptonite. Messes up my mitochondria almost instantly after inhalation of even miniscule amounts.

  • @rggu-tk7ed
    @rggu-tk7ed 4 หลายเดือนก่อน

    Great vid! As usual, great information and cool presentation

  • @thelakeman2538
    @thelakeman2538 7 หลายเดือนก่อน +1

    Bacteria can evolve UV resistance, there are some extremophilic bacteria and archaea which are resistant to UV and other ionizing radiation but chances are your average pathogenic bacteria will never be able develop or obtain genes for something like that.

  • @ChineseKiwi
    @ChineseKiwi 7 หลายเดือนก่อน +1

    5:27 - Thanks, I’m on yet another watchlist from your videos 😂

  • @holdenleeb2312
    @holdenleeb2312 7 หลายเดือนก่อน +1

    I literally had that exact bottle of phenol chloraseptic sitting next to me when it popped up

  • @Toklwartooth
    @Toklwartooth 7 หลายเดือนก่อน +2

    Fucking love disinfectant lore

  • @carlislenash6111
    @carlislenash6111 7 หลายเดือนก่อน

    I didn’t realize this was another “try to get demonetized” video, love the Danny Devito easter egg

  • @katiefrisk980
    @katiefrisk980 7 หลายเดือนก่อน +1

    One upside of bromine as a disinfectant is the higher pKa of HOBr, meaning that more of it is in the active protonated form in neutral pH. If you add some baking soda to chlorine bleach nothing will happen initially (because it is not strong enough of an acid to significantly protonate NaOCl), but add a milligram of sodium bromide and it will turn orange from the HOBr.

  • @ElectronicMusicDaemon
    @ElectronicMusicDaemon 7 หลายเดือนก่อน

    I'm really afraid of phenol because when I had it stored in its original plastic container the smell wouldn't stop coming out. And the problem did not disappear when I put it in a borosilicate glass tube with a screw cap and PTFE liner. The problem was solved when I wrapped the lid with several turns of Teflon that sold in hardware stores.

  • @INeedAttentionEXE
    @INeedAttentionEXE 7 หลายเดือนก่อน +1

    9:31 As a non-chemist all I heard was Dale Dimmadome.

    • @nicholasneyhart396
      @nicholasneyhart396 7 หลายเดือนก่อน

      To be honest, I am a chemistry major, and that's all I heard my first time listening also.

  • @_Pilots
    @_Pilots 7 หลายเดือนก่อน +2

    As a chemistry lover, this video is amazing!

  • @disorganizedorg
    @disorganizedorg 5 หลายเดือนก่อน

    Propylene glycol also finds use as an antifreeze in potable water lines (RVs, seasonal cabins, etc).

  • @dragoon0anime
    @dragoon0anime 7 หลายเดือนก่อน +1

    "Chlorhexidine is also used in toothpaste..."
    Me: Cool.
    "...and is also possible that chlorhexidine may be a potential carcinogen."
    Me: WTF? (I'm running to check my toothpaste ingredients.)

  • @suspicaxrohde2310
    @suspicaxrohde2310 7 หลายเดือนก่อน

    Fun fact! Phenol is still used today in clinical microbiology laboratories. Phenol itself is a common part of AFB stains (looking for mycobacteria, like tuberculosis) because it both kills the bacteria and fixes them to the slide. Lactophenol is part of fungal stains for similar reasons. As both of those classes of organisms can be easily transmitted by breathing in the primary specimen, it's important to set them up in a biological safety cabinet, but then be able to read them under the microscope when all the organisms are dead.

  • @perdo1123
    @perdo1123 7 หลายเดือนก่อน

    I’m loving all the water treatment shoutouts as I’m sitting in a water treatment plant.

  • @liam3284
    @liam3284 7 หลายเดือนก่อน +1

    We use 70% isopropyl alcohol to clean up circuit boards and electronics. Didn't know it also disinfects them, nice.

  • @WafSyir
    @WafSyir 7 หลายเดือนก่อน

    thanks for the drinks tier list, much appreciated

  • @moonman2183
    @moonman2183 7 หลายเดือนก่อน

    7:10 Was not expecting a sudden reference to the infamous "jar". Wow.

  • @leon13noelspy
    @leon13noelspy 7 หลายเดือนก่อน

    A common disinfectant that i would’ve wanted to see in that list is Virkon S. Sometimes also called Oxone or Potassium peroxymonosulfate. It is very commonly used to kill virusses, bacteria and fungi/ molds. A friend of mine works in a viral lab and uses this stuff quite alot to clean equipment and surfaces. It’s pretty great

  • @gamereditor59ner22
    @gamereditor59ner22 7 หลายเดือนก่อน +1

    Thanks for the educational and keep it up!

  • @Rachel-sx8zw
    @Rachel-sx8zw 7 หลายเดือนก่อน +1

    Ethylene oxide is also is used in some fuel-air explosives. If it fails to fully ignite, it effectively functions as chemical weapon.

  • @foracal5608
    @foracal5608 7 หลายเดือนก่อน +6

    Chlorine trifluorine is a very good disinfectant... .. in theory sorry I still have flash backs as i have said in the past with fluorine compounds...

    • @musashi939
      @musashi939 7 หลายเดือนก่อน +1

      You need good pair of running shoes, when it comes to metal fluorine fires 😂

    • @foracal5608
      @foracal5608 7 หลายเดือนก่อน

      @@musashi939 or already in a rocket

    • @musashi939
      @musashi939 7 หลายเดือนก่อน

      @@foracal5608 true. But that mentioned incident in Ignition! happened during testing and it burned through a 1m thick concrete base. As far as I remember.

  • @alext6933
    @alext6933 7 หลายเดือนก่อน +1

    Epclusa and vosevi are my fav anti virals. Yes I have worked with needles before.😊😊

  • @mateoarevaloyazzo6113
    @mateoarevaloyazzo6113 2 หลายเดือนก่อน

    Man, excellent video. Can you do one video of the best chemicals for cleaning and decontamination of indoor spaces?

  • @nightchicken3517
    @nightchicken3517 4 หลายเดือนก่อน

    Dude best ad for a mic ive seen

  • @Xolvi9
    @Xolvi9 4 หลายเดือนก่อน

    Of all the places i didnt expect to hear S3RL.

  • @debrucey
    @debrucey 7 หลายเดือนก่อน

    Hypochlorous acid is my personal favourite, so gentle on skin compared to most of the others so great for disinfecting cuts. I spray it in my shoes too

  • @lefthandedspanner
    @lefthandedspanner 7 หลายเดือนก่อน

    speaking as someone who used to formulate mouthwashes for a living, chlorhexidine is by far the most temperamental material I have ever worked with
    it really doesn't like salts or alcohol, so you'd often struggle to add fluoride, sweetener or preservative to the formula without the chlorhexidine crashing out

  • @rocknrollmanic
    @rocknrollmanic 7 หลายเดือนก่อน +1

    Potassium Permanganate should also come with a mention of Permangatic Acid. Shit's scary but fun to play with

  • @Godwh1sperer
    @Godwh1sperer 7 หลายเดือนก่อน +2

    Forgive me, but this is in my opinion the first low quality member in your high quality series. You are always reliably rigid in your criteria for the tiers, as one would expect. In this installment you move goal posts frequently and because of it, the disinfectants are spread across the tiers more or less randomly. If some mundane disinfectants make it to S-tier but UV, primary disinfectant in atmosphere and ocean and huge industry, ends up in F-tier, isopropanol and ethanol in B-tier on equal footing above phenol, chlorine above hypochlorite.. Its inconsistent in a way i think is a step down in a great series. Please reaffirm consistency for future productions. Don't jump the shark :)

  • @GrowthCurveMarketing
    @GrowthCurveMarketing 7 หลายเดือนก่อน

    Great clip! Informative and comprehensive. That said, while it’s primarily used as a biocide preservative in things like growth media, I’m surprised you didn’t cover sodium azide. It’s remarkably potent, effective, and persistent.

  • @ESTrashfire13
    @ESTrashfire13 7 หลายเดือนก่อน

    99% isopropanol is used in bowling alleys to clean the run-up to a lane, to clean them and leave a somewhat slippy feel, that is more resilient to moisture than talc powders.

  • @willswanson1840
    @willswanson1840 7 หลายเดือนก่อน

    The Br + O3 reaction is problematic enough that ozone-based water treatment processes have to be suspended even at fairly low bromide concentrations. I used to work at a treatment facility that used O3 primarily to oxidize the hell out of triazines, and we were checking bromine levels about every half hour when the river was above a certain stage. An old oil operation was leaking produced water from substandard brine pits, and the bromides in the PW were on the order of 1100 ppm.

  • @quincyboyce845
    @quincyboyce845 7 หลายเดือนก่อน

    the s3rl music..... mr thatchemist you have made my day. this video has 3 of my special interests at once!!!!

  • @kaliumthiocyanat6211
    @kaliumthiocyanat6211 7 หลายเดือนก่อน

    Okay I really love the mic ad :D

  • @transcendtient
    @transcendtient 7 หลายเดือนก่อน +1

    I haven't watched the video yet, but I can tell you what I use around the house is 80% white vinegar and 20% ethanol (Everclear).

  • @user-mk6ee5lk8e
    @user-mk6ee5lk8e 7 หลายเดือนก่อน

    Thank you very much, it was very interesting.

  • @OmegaPaladin144
    @OmegaPaladin144 7 หลายเดือนก่อน

    I worked at a disinfectant manufacturer for a while, before moving into laboratory safety, so naturally I have a few comments:
    You forgot Chlorine Dioxide! It's a really good disinfectant both in solution and for sterilizing an area in gas phase. We use it for cleaning biosafety cabinet filters and the animal researchers use it as their main disinfectant. I've also heard it has been used as a mouthwash for severe bad breath. It has a similar method of action to Chlorine , just with less unpleasant byproducts.
    Thymol is probably the most commonly used disinfectant natural product. It's the main active ingredient in Listerine and many "natural" disinfectants. It's basically a phenolic compound that smells nice and is fairly non-toxic.
    Quats and Chlorhexidine rely on their positive charge centers to work. They will be inactivated by most common detergents, which are anionicsulfonic acid salts. This is why you can't mix them with soap. Quats are the go-to disinfectant for something that wouyld be corroded by bleach.
    I've used phenol throat spray - I believe the phenol is more there as an anesthetic. It tasted pretty bad.

  • @klocugh12
    @klocugh12 7 หลายเดือนก่อน +2

    One thing you should be able to mix bleach with is lye. In fact most bleaches contain a little NaOH as NaClO is more stable in basic pH. Which is also why it is a really bad idea to wash your hands in them. They also permanently remove dyes from clothing, which many think is a stain, but it is not. You don't wash it away, you have to reintroduce the dye.
    Note that doesn't mean you can mix bleach with lye-based cleaners due to other stuff they may contain (notably aluminium flakes).
    What about merbromin (mercurochrome)?

    • @Humbulla93
      @Humbulla93 7 หลายเดือนก่อน

      If you dillute the bleach enough then it won't discolour the clothes

    • @klocugh12
      @klocugh12 7 หลายเดือนก่อน

      @@Humbulla93 if you dilute HCN enough, it won't kill you either.

  • @TwiztedEU
    @TwiztedEU 7 หลายเดือนก่อน

    Loved the synthesis hardcore!

  • @charleshines2142
    @charleshines2142 7 หลายเดือนก่อน

    That phenol formaldehyde resin is Bakelite and it is a hard and durable plastic that was used for wall electrical sockets and a variety of other things. If you lived in an older house and plugged things in the front of that socket that everyone sees may have been made from that. I think it was an accidental discovery while doctors were trying different kinds of anesthesia. Of course that would be in the earlier years when we used to use dangerous compounds that we now would not use for that same purpose again .

  • @squigglycups5666
    @squigglycups5666 7 หลายเดือนก่อน +2

    Degreaser tierlist please 😂😮😅😢😅🎉

  • @burnblast2774
    @burnblast2774 7 หลายเดือนก่อน

    If I was to guess about bromine in hottubs, I would think that is higher molecular weight probably makes it and it's compounds less volatile than their chlorine equivalents at higher temperatures, therefore making the hottub smell less like pool.

  • @elitequeef
    @elitequeef 7 หลายเดือนก่อน

    damn big homie got the microphone spot but the shure sm7xx in the bg lol :P stay frosty mi amigo.

  • @Playguu
    @Playguu 7 หลายเดือนก่อน +1

    Damn, bro really did light dirty like that huh

    • @LittleKikuyu
      @LittleKikuyu 7 หลายเดือนก่อน

      „It’s not a chemical…F“
      dang! Light got buuurned.

  • @MrGatlin98
    @MrGatlin98 7 หลายเดือนก่อน

    Hey I've had the nailbed "disinfectant" procedure! Twice! Because the nail decided to grow back despite the phenol.

  • @oh_jeebus1021
    @oh_jeebus1021 7 หลายเดือนก่อน

    I thought the title asked What chemical tastes the best and that tism had me reeeeeeeeal excited

  • @OPNotes
    @OPNotes 7 หลายเดือนก่อน

    Ototoxicity does not require placement in the ear. This usually refers to ingestion or absorption through the skin, then causing damage to the inner ear.

  • @sipntea
    @sipntea 7 หลายเดือนก่อน

    2 that chemist video's in the same day!? christmas came early!

  • @shadowpoet4398
    @shadowpoet4398 7 หลายเดือนก่อน

    15:00
    Propylene Glycol is a blistering agent if you're allergic. It's not as safe as people try to make it seem. More and more people are, through exposure, developing allergies which make reactions to all other glycols in food, cosmetics, drinks, etc. Only when it's polymerized is it hypoallergenic

  • @jeffhutjens
    @jeffhutjens 7 หลายเดือนก่อน

    Hydrazine is also found in common button mushrooms. You breathe it while you cook them. One mushroom expert questions whether they should be eaten at all.