How to prove discriminatory power of a dissolution method?

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[@bkalyan7555]

Good information

[@analystreportor899]

Hi, if we are not able to get sufficient discrimination to have f2 value below 50 for batches with meaningful variation and process changes, wha to do?
Develop another media?
or change apparatus or media volume?
For some products wit is almost difficult to get discrimination for eg. DR formulation