Will NSAIDS RUIN YOUR GAINZZZ?
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- เผยแพร่เมื่อ 20 ก.พ. 2018
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Timing of ibuprofen use and musculoskeletal adaptations to exercise training in older adults.
www.ncbi.nlm.nih.gov/pubmed/2...
Effect of ibuprofen and acetaminophen on postexercise muscle protein synthesis.
Trappe 2002
www.ncbi.nlm.nih.gov/pubmed/1...
Influence of acetaminophen and ibuprofen on skeletal muscle adaptations to resistance exercise in older adults.
www.ncbi.nlm.nih.gov/pubmed/2...
Nonsteroidal Anti-Inflammatory Drug Use and Endurance During Running in Male Long-Distance Runners
www.ncbi.nlm.nih.gov/pmc/arti...
Resistance Training with Co-ingestion of Anti-inflammatory Drugs Attenuates Mitochondrial Function
www.frontiersin.org/articles/...
Muscle and tendon connective tissue adaptation to unloading, exercise and NSAID.
www.ncbi.nlm.nih.gov/pubmed/2...
Mikkelsen UR, Schjerling P, Helmark IC, Reitelseder S, Holm L,
Skovgaard D, Langberg H, Kjaer M, Heinemeier KM. Local
NSAID infusion does not affect protein synthesis and gene
expression in human muscle after eccentric exercise. Scand J
Med Sci Sports 2010;6:1-15.
www.ncbi.nlm.nih.gov/pubmed/2...
Carroll CC, Dickinson JM, LeMoine JK, Haus JM, Weinheimer
EM, Hollon CJ, Aagaard P, Magnusson SP, Trappe TA. Influence
of acetaminophen and ibuprofen on in vivo patellar tendon
adaptations to knee extensor resistance exercise in older adults.
www.ncbi.nlm.nih.gov/pubmed/2...
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Lost video footage somehow between California and Australia of this podcast, but the audio is still here so I posted the podcast here and on iTunes. Check it out! What do you wanna hear about next?
Barbell Medicine
If I'm 220 and I need a gram or so of protein per pound of body weight, but my diet is like 4000 calories a day right now, should I eat like 3-400 grams of protein to keep my macro ratios from going haywire, or does it all go out the window once I meet my protein goals?
Nah, I'd stick at 220g.
Surprising answer, but you're the pros. Longtime viewer and nutrition major, but i have a ton to learn. Thanks guys!
Barbell Medicine I'm interested in promoting tendon and ligament health (how important is static stretching, nutritional needs etc.). I would be grateful for any information you guys can share on the topic. Thanks
I would love for you guys to do a podcast on treating spinal injuries. You've stated in many forms of media(and other guys in SS videos) that training with a back injury is safe and the best way to recover. It appears that you guys always leave it at that, often providing evidence of how other recommendations are proven not to be effective and then stating that training is safe and to do it, but that's kind of it. I would be very interested to hear specifics on how training impacts spinal injuries and recovery, such as what kind of reduction in radiculopothy symptoms can be expected and what mechanisms influence that process. The doctor of PT in last year's SS seminar had a lecture about spinal pathology that was very informative and provided a detailed overview of different conditions and when it is and is not safe to train and any precautions that should be taken for each. I would be interested in the follow-up to that which would detail how barbell training can improve, mititage, or eliminate some of those symptoms/conditions.
Additionally what Edward suggested about soft tissues interests me but my coach told me you guys are writing an article about tendonopathy and I imagine you'll do a podcast either here or with rip once it's published.
15:10 For beginning of NSAIDS discussion
Cuandoman Thank you!
How come Jordan is just standing still with his arms folded during the video? I can't even see his mouth move. Is this some kind of isometric exercise? How much nuance should I use?
He's using telepathy.
Even more so, it's 531 texas methepathy.
Start with a small dose of nuance and slowly titrate up.
Ventriloquism is proven to be anabolic [citation not needed]
Been taking baby aspirin daily for a month.. and I have been still making hypertrophy and strength gains. However, I am not taking it for pain or inflammation per se. I read that low-dose aspirin can prevent blood clots by thinning the blood. Do y'all recommend taking baby aspirin everyday?
Thanks for the video BBM team!
Hey, great content in this podcast. I had read about ibuprophen killing gainz and I believed it when I read it 6 months ago. However recently I began questioning the article because it didnt display any data other than one study... thanks for covering this topic.
I was diagnosed with ankylosing spondylitis back in early August last year and am going in for my second infusion of simponi aria. I’m also prescribed to take meloxicam every day as well, and I can finally say, after having symptoms for 3 years of my life, I feel great. NSAIDs and other pain relievers have done so much good for me, and I feel stronger than ever in the gym. Thanks for the informative video as always guys!
great info guys!!! thank you! love the content
Awesome info guys, thanks. I think it's great you're taking the time to spread some medical knowledge. Noticed a small thing though: when discussing generic and brand names of common NSAIDs I think Austin was offering up meloxicam as another common NSAID. The brand name for PO dicofenac is Voltaren, just like the topical and the brand name of meloxicam is Mobic (sorry to sweat the irrelevant details, PharmD here).
Hey Dr. Feigenbaum, running the Bridge 2.0. Hella gains, not even my final form. Added about 100+ pounds to my total. Thank you for the great programs and information!
Perfectly timed episode. I was just thinking about this.
Great content as always
Just signed up for the group programming. ✊🏼
41:50 and after is when they start to talk about effect of NSAIDs on strength & hypertrophy -- before that is more general discussion of what NSAIDs are (Tylenol is not considered an NSAID by these guys), and what they are useful for. Nice podcast, men, and thank you, Jordan, for the still photo, because I use a laptop for these podcasts and I don't like being shown just an image someone drew, like in the traditional Barbell Logic podcasts (I assume those will change to video, now that those guys are taking over the Starting Strength podcast from Rip). Since your video got lost somehow, it's still a lot better to see your photo. And Austin's looking great, as always! Thanks for this info, which was timely for me as a novice lifter.
This is cool! I did my master's thesis on the shedding of lectins by leukocytes, cause by NSAIDS and chemically similar insecticides. This is all consistent with what I've seen (not that it has to, it's a little validating), makes good sense!
42:50 The 12 year old inside of him wanted to giggle when he said "cox" enzyme. lol
Missed this old podcast. I used to take a ton of these when I wrestled.
A while back Austin mentioned that you could do an entire podcast on tendinopathy. I would very much like to see this happen.
Cox1 and cox2? And to think this whole time I only thought I had the one...
If someone begins to develop tennis or golfers elbow from too much volume at too high of intensity is there any effective treatment outside the obvious longer term solution of adjustment of their training protocols?
When i do pendlay rows I pretty much just drop the weight also. So I do basically just do the concentric part of the movement.
My hands stay on the bar so I am technically doing eccentric but I dont control it so.....
I've been taking Naproxen to deal with chest pain (likely inflammation of the sterno-costal joints - costochondritis). I'm on my third month. Do you have any opinion of use in this manner?
Pliny the Elder died in 79 AD. Gonna take a wild guess here and assume willow bark was available in the Old World, long before the New World was discovered.
You should educate Barbell Logic on the topic of low t.
Hey Jordan, why did you stop posting some workout videos? :(
Arachidonic Acid. I like you guys.
Wait what Jordan is coming to AUS? Is it a tour/talk thing or just a holiday?
Enjoy your stay Jordan!
oranac he’s already here, probably going back soon.
can you review smolov?
In some insta post you mentioned regular soda as one of the "10 things to live without". But some respectable coaches like Mike Israetel and Stan Efferding recommend sugar around workout to replenish muscle glycogen. Are there any adverse effects of sugar consumption (provided protein, fat, fiber and micronutrient intakes are suffiecient)? I request a nuanced caveat on sugar
Meh, you can have simple carbohydrates around workouts if you like, but it doesn't matter really. If you love soda- go for it, but it's not better or worse given this context.
Cool, sounds like everyone tries to make nutrition more complicated than it really is
Been taking baby aspirin daily for a month.. and I have been still making hypertrophy and strength gains. However, I am not taking it for pain or inflammation per se. I read that low-dose aspirin can prevent blood clots by thinning the blood. Do y'all recommend taking baby aspirin everyday?
I know Rip likes explosive (Pendlay) rows, but I never got a sense of why. He also likes to do shrugs in an explosive manner ("power shrug").
What's the advantage of doing these exercises explosively rather than, say, in a slower, more controlled fashion?
its a trade - more weight, power, harder contraction vs. more time under tension aka more volume per rep, more stretch
depending on your leverages its also very very hard to do a slow negative with your torso parallel to the ground
Found the barbell row question bit so funny.
Also;
"Until you have an auto-immune disease, then they're all psychotic and going crazy" 😆
Totally have MS. Just did the alemzumutab treatment and it RUINED MY GAINZZZ 🙄
Let's get this group programming started guys!!!
Hey Austin and Jordan. I have terrible headaches, pretty much daily and I take way to much ibuprofen to cope. I have been to several MDs and had a few scans done, with no progress or even suggestions on what to do. I have a good diet, I exercise daily, and drink tons of water. Can you recommend any pain management information for me?
Steven Truant
How about stop taking ibu ...if its "way too much" and isnt effective anyway lol
John Constantin where did I say it wasn’t effective? It’s extremely effective at stopping the pain.
Been taking baby aspirin daily for a month.. and I have been still making hypertrophy and strength gains. However, I am not taking it for pain or inflammation per se. I read that low-dose aspirin can prevent blood clots by thinning the blood. Do y'all recommend taking baby aspirin everyday?
I have jacked up knees including patellar tendons. Aspirin is good for patellar tendon? Motrin is not?
Millions of older individuals consume acetaminophen or ibuprofen daily and these same individuals are encouraged to participate in resistance training. Several in vitro studies suggest that cyclooxygenase-inhibiting drugs can alter tendon metabolism and may influence adaptations to resistance training. Thirty-six individuals were randomly assigned to a placebo (67 ± 2 yr old), acetaminophen (64 ± 1 yr old; 4,000 mg/day), or ibuprofen (64 ± 1 yr old; 1,200 mg/day) group in a double-blind manner and completed 12 wk of knee extensor resistance training. Before and after training in vivo patellar tendon properties were assessed with MRI [cross-sectional area (CSA) and signal intensity] and ultrasonography of patellar tendon deformation coupled with force measurements to obtain stiffness, modulus, stress, and strain. Mean patellar tendon CSA was unchanged (P > 0.05) with training in the placebo group, and this response was not influenced with ibuprofen consumption. Mean tendon CSA increased with training in the acetaminophen group (3%, P < 0.05), primarily due to increases in the mid (7%, P < 0.05) and distal (8%, P < 0.05) tendon regions. Correspondingly, tendon signal intensity increased with training in the acetaminophen group at the mid (13%, P < 0.05) and distal (15%, P = 0.07) regions. When normalized to pretraining force levels, patellar tendon deformation and strain decreased 11% (P < 0.05) and stiffness, modulus, and stress were unchanged (P > 0.05) with training in the placebo group. These responses were generally uninfluenced by ibuprofen consumption. In the acetaminophen group, tendon deformation and strain increased 20% (P < 0.05) and stiffness (-17%, P < 0.05) and modulus (-20%, P < 0.05) decreased with training. These data suggest that 3 mo of knee extensor resistance training in older adults induces modest changes in the mechanical properties of the patellar tendon. Over-the-counter doses of acetaminophen, but not ibuprofen, have a strong influence on tendon mechanical and material property adaptations to resistance training. These findings add to a growing body of evidence that acetaminophen has profound effects on peripheral tissues in humans.
Mark Wurtz yes but what does it mean? Arent most patellar tendon problems the result of improper patellar tracking?
Edward Goose I suppose so
I certainly don't know, and thats really interesting about acetaminophen potentially supporting an increase in CSA of the tendons in the knee. The question is does this mean less knee pain? Again I dont know. I'd be interested to hear more though.
Been taking baby aspirin daily for a month.. and I have been still making hypertrophy and strength gains. However, I am not taking it for pain or inflammation per se. I read that low-dose aspirin can prevent blood clots by thinning the blood. Do y'all recommend taking baby aspirin everyday?
As a Classicist I have to warn you, don’t listen to a thing Pliny the Elder says on medicine
54:55 "Getting your testosterone to go from 300 to 900 is meaningless." Is this really true?