Insanely interesting topic. I recently found you through Hidden Forces. Your podcast is a treasure trove of intellectually stimulating content. I feel like I'm auditing a university course, for free, from my own home, which is just amazing. Thank you.
Doesn’t natural selection technically always have to act on existing variation? Any new mutations technically has to exist as a variant/variation in a population before selection, right?
Yes, that's correct. The distinction here is between rare (in an extreme case, de novo mutation) and common variants (already present in the population but with varying allele frequencies). Some discussions of evolution / natural selection focus on mutations, but the most rapid response to selection (cf polygenic traits) is typically changes in allele frequencies.
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Insanely interesting topic. I recently found you through Hidden Forces. Your podcast is a treasure trove of intellectually stimulating content. I feel like I'm auditing a university course, for free, from my own home, which is just amazing. Thank you.
Thanks for interesting lecture.
Doesn’t natural selection technically always have to act on existing variation?
Any new mutations technically has to exist as a variant/variation in a population before selection, right?
Yes, that's correct. The distinction here is between rare (in an extreme case, de novo mutation) and common variants (already present in the population but with varying allele frequencies).
Some discussions of evolution / natural selection focus on mutations, but the most rapid response to selection (cf polygenic traits) is typically changes in allele frequencies.