Pharm1- What is Pharmacology? Introduction to Pharmacology
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Pharmacology: the study of substances that interact with living systems through chemical processes, especially by binding to regulatory molecules and activating or inhibiting normal body processes.
A drug: may be defined as any substance that brings about a change in biologic function through its chemical actions.
Katzung, Bertram G., Susan B. Masters, and Anthony J. Trevor, eds. "Basic & clinical pharmacology." (2012).
The drug molecule interacts as an agonist (activator) or antagonist (inhibitor) with a specific molecule in the biologic system that plays a regulatory role. This target molecule is called a receptor .
The actions of the drug on the body are termed Pharmacodynamic Processes
The actions of the body on the drug are called Pharmacokinetic Processes
Drug affinity: the tendency of two substances to form strong or weak chemical bonds forming molecules or complexes.
Drug Efficacy: the ability of a drug to produce the desired therapeutic effect.