Peak Purity By HPLC-PDA Detector

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  • เผยแพร่เมื่อ 18 พ.ย. 2024

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  • @rahulmahey5509
    @rahulmahey5509 2 ปีที่แล้ว +2

    I was exhausted by not finding any data regarding this topic. But this video has become a sun in darkness. I am not that smart or fast to catch these things completely. For a complete understanding of this topic, I have to watch this several times. I really appreciate this sharing of knowledge.
    But if u read this, I have a small query in my mind (could be a silly one): As the conc. of analyte increase, the absorption(AU) increase as well. So how can there be homogeneity b/w spectrum of two points in peak.

    • @drarvindmittal7353
      @drarvindmittal7353  2 ปีที่แล้ว

      Hi Rahul, Happy to note that this topic is meaningful to you. For appropriate evaluation of peak purity of a component, it has to be in linear dynamic scale of PDA scale. Too high a concentration will distort the peak purity results. One should keep in mind the concept of Beer and Lambert's Law. Hope this will help.

  • @sasidhargovardhanam5689
    @sasidhargovardhanam5689 4 ปีที่แล้ว

    Thank you so much, Dr. Arvind Mittal sir. This video is a really good example for understanding the peak purity. The explanation was clear and excellent, Keep posting.

  • @pardeepchauhan990
    @pardeepchauhan990 2 ปีที่แล้ว

    Good to see you sir after such a long time. Very good presentation, helped a lot in understanding how peak purity is calculated. Keep posting more videos.

  • @krish_krish354
    @krish_krish354 4 ปีที่แล้ว

    Good explanation sir do more videos

  • @AbdelsalamZidan-v4z
    @AbdelsalamZidan-v4z หลายเดือนก่อน

    I need to measure glucose using this detector but I dont know the best column for this?

  • @rafaeldossantoscosta133
    @rafaeldossantoscosta133 5 ปีที่แล้ว

    Thanks! Nice explanation!

  • @SG73088
    @SG73088 4 ปีที่แล้ว

    Nice lecture

  • @porwalpawan
    @porwalpawan 6 ปีที่แล้ว

    nice explanation

  • @NarcisseIsu
    @NarcisseIsu หลายเดือนก่อน

    Min 14:30 of the video - when the Resolution of detector increase, better Purity Test will occur- Here the Resolution is the Spectral Resolution = the distance between two consequential Data point on the spectrum and the smaller it is, more data points has shaped the peak.

  • @liwenyan2790
    @liwenyan2790 4 ปีที่แล้ว

    thanks

  • @krish_krish354
    @krish_krish354 4 ปีที่แล้ว

    How to know the interference using 3d structure. While peak purity reduced

  • @chauhanshubham4872
    @chauhanshubham4872 4 ปีที่แล้ว

    Kindly update hplc method development for related substance a deatiled account.

  • @tej9763
    @tej9763 2 ปีที่แล้ว

    In peak purity peak .8 to 1.2 is it necessary

    • @drarvindmittal7353
      @drarvindmittal7353  2 ปีที่แล้ว

      No! Probably you are correlating it with peak symmetry.

  • @jian658
    @jian658 6 ปีที่แล้ว

    thank you , but can not hear very clear

    • @drarvindmittal7353
      @drarvindmittal7353  6 ปีที่แล้ว

      jian658 Yes voice quality is not good. However, if you use earphones/headphones then there shouldn't be any problem.
      Thanks for drawing my attention to this issue. I shall try to improve futher.