ไม่สามารถเล่นวิดีโอนี้
ขออภัยในความไม่สะดวก
First CRISPR Gene Editing Treatment | How does it work?
ฝัง
- เผยแพร่เมื่อ 14 ส.ค. 2024
- The first ever CRISPR gene editing treatment just got approved in the US and UK and this is a huge step!
But what’s the story behind this revolutionary technology?
Bio:
I am a Medical Doctor currently working in the NHS & Science and Health Writer making content about Scientific and Medical findings from around the world!
Resources:
elifesciences....
www.science.or...
www.ncbi.nlm.n...
www.nejm.org/d...
www.nhlbi.nih....
doudnalab.org/
www.nytimes.co...
www.theguardia...
www.wired.com/...
www.quantamaga...
• FDA Approves First Cri...
• FDA approves groundbre...
• UK approves gene thera...
• Fmr. FDA Commissioner ...
• Can CRISPR cure Sickle...
• How CRISPR lets you ed...
Very good explanation as to what CRISPR is and incredible to see the principle behind its use in Sickle Cell Disease- was not aware that we have different forms of haemoglobin! Thank you for this informative video, looking forward to your next ones!
Thank you for your support!🙌🏻
Crisper also used to treat HIV
use of hiv cured crispr treatment updates please
Magic Johnson, duh!
Imagine a functional cure for HIV infection The savings to the medical and Health insurance sectors would be beyond comprehension Africa and India urgently need a cure .
Pronto saldrá la cura del VIH 💪🌞🙏🏻🧬🔬🌎🫂💫💫💫
Great video, the only thing to consider is extraneous cognitive load like unneeded music and graphics. This adds additional information and makes hearing what you have to say a little harder than it should be.
Thank you for your feedback!! 🙌🏻 will work on it for the next ones!
I remember my genetics teacher saying crispr would use a viral vector to transmit the genes to all the tissue, seems like that would make more sense than putting patients through chemo. why is it we are doing it this way?
Greed.
Chemo kills all the cells including healthy ones. This technique seeks out cancerous ones to lyse* without killing the healthy parts.
I am interested more in what will crisper be used for next than what happened already
Can they cure asthma? I will be a test subject!
Asthma is not inherited. You can't gege pluck that one.
Give those scientists what they need .
Today CRISPR is creating a revolution, a new knowledge that might be able to allow us to understand human evolution
CRISPR totally is changing everything❤
It disrupts natural selection. Spartans would take deformed babies and kill them in order to rid themselves of bad genes. It didn't work. Genes will change naturally even in different environments. Genes will mutate naturally. It's altering nature to pluck out chromosomes. There isn't enough research on what the results are. We are all different. We aren't designer purses. If it's illegal for parents to chop off a child penis and give it a vagina why is it legal to alter an unborn embryo. Life begins at fertilization. It should be illegal. It is immoral. There's no choice for a human to be what possibly "God intended. " You can change the gender of your baby. Will the child grow up knowing it's parents mutated it and feel loved? Will it feel normal? Will it be abnormal? How will a mutated child feel during adolescence? No one cared enough to check first. They just call it designer baby but eliminated God's grand design. There will be consequences.
Love.crisper.all for curing genetic.disease
Actually, CRSPR been around for about 10 years already. And it just blew up in recent years among the population. It's a little scary to think what it's capable of doing.
That's God's work ya know...
if you focus on explaining recent good papers in the medical field that would be awesome!
gave ya a sub
Thank you for your support!🙌🏻
Hi
When we can expect a cure for Hiv ...
Never, they made that too
By 2030 or before
Lets hope that our Gain of Function experts make a new and better virus and save the planet.
Nice.
No such luck. They made a more virulent one that kills us faster now.
Wasnt the first the recent RNA vaccines? 🤔 Or this is the first approved..
Hi! Thank you for your comment!
This is the very first CRISPR-Cas9 gene editing therapy approved by FDA and UK’s regulator. In the US it is approved for SCD at present and in the UK for both SCD and transfusion-dependent β-thalassemia.
Very good question !
mRNA or messenger RNA is a single stranded copy of DNA. Each strand of mRNA holds the information on how to make one type of protein. Our cells have ribosomes within them- These are its machinery to make new proteins. Ribosomes basically read the mRNA, following its instructions and making the protein (as per the mRNA instructions)
There are some vaccines which were made based on these principles- called mRNA vaccines.
CRISPR-Cas system is different as it uses a guide RNA (gRNA), not a messenger RNA (mRNA). The CRISPR-Cas system cuts the actual DNA sequence itself, based on its guide RNA (gRNA). The gRNA basically tells this system where to cut. On the other hand, messenger RNA (mRNA) acts as an instructor for the cell’s machinery system, called ribosomes- instructing them which protein to make.
4:34
Mutants coming!
It being 'approved' this quickly is irresponsible and dangerous. This is not only new tech, but there are no long term results available. Who knows what kind of effects it may have in the long term or on offspring? You know what happens every time a radical new treatment or drug gets pushed through without thorough testing? Big problems start to occur. Every. Single. Time.
the populations most affected by sickle cell is why they approved it so fast...test subjects...long history of that if you know His Story.
@@charlesatlas9124 And even with that it's impossible to normally get approval that fast for a method using new and unproven tech. And more importantly, the incredibly high risks that come with this.
If this affects the genetics of offspring, it will spread like wildfire after a few generations and chances are it could lead to some serious issues. Worst case scenario it could doom the entirety of humanity.
@@thenonexistingheroI doubt purifying selection of the genes that cause sickle cell anemia would doom all of humanity. The real problem is how accurate the Cas-9 enzyme is at doing it’s job. I don’t think accidental changes around the gene are something we want. Luckily, we’re already working on mitigating this using prime editing (this method way more accurate)
@@midnitemoon1153 That's all theory, by the time they find out something's wrong it's too late. And yes, it could very well eliminate humanity entirely. Even if they only do it on a few hundred a year, within 100 years the majority of humanity could already carry altered genes even assuming it's only used for sickle cells, but...
It's not going to stop with sickle cel, they are going to use gene altering tech for all kinds of things and likely also for handpicked traits so parents can get their perfect children.
I'm not exagerating when I say that this kind of thing could result in the extinction of humanity. Has the past decade not taught you anything with just how many miracle drugs and treatment they rushed to the market for profit, only for it to backfire?
It'd be one thing if this kind of research was done to better humanity. It would result in very careful research. But it's not, it's done to make a profit and that's why it's so dangerous. Short term profit doesn't care about long term survival of the human race.
😂