Mass Spectrometry

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  • เผยแพร่เมื่อ 25 เม.ย. 2016
  • Who wants to smash molecules into little bits? A mass spectrometer does, that's who. This is a good technique for corroborating molecular structure, because we can make sure the puzzle pieces fit the right way. Check it out!
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ความคิดเห็น • 236

  • @taffyroosevelt7809
    @taffyroosevelt7809 4 ปีที่แล้ว +1231

    You know a topic is hard when even Professor Dave starts to sound confusing.

    • @cloudykumori8985
      @cloudykumori8985 ปีที่แล้ว +12

      😭😭😭😭 it makes no sense

    • @fancytracy
      @fancytracy 8 หลายเดือนก่อน +5

      What is confusing about this video lmao

    • @zeynepkoksal7228
      @zeynepkoksal7228 8 หลายเดือนก่อน

      tamam en çok sen biliyon sana çok kolay ezik maymun@@fancytracy

    • @mohammaddaud6585
      @mohammaddaud6585 6 หลายเดือนก่อน +7

      Your comment popped up first and gave me anxiety, it isn't confusing. It's just that probably you don't know sufficient scientific vocabulary

    • @taffyroosevelt7809
      @taffyroosevelt7809 6 หลายเดือนก่อน +16

      @@mohammaddaud6585 Sincerest apologies that my scientific vernacular isn’t up to your standard

  • @rosablackwell64
    @rosablackwell64 5 ปีที่แล้ว +308

    I work for a university. I watch Professor Dave's videos because he explains this stuff better than my own faculty.

  • @montsermuro3087
    @montsermuro3087 3 ปีที่แล้ว +88

    I literally watched over 20 videos trying to understand this, and this was the ONLY one that helped. Thank you x100000000

  • @Kvng375
    @Kvng375 5 ปีที่แล้ว +572

    4 minutes with you is more effective than 120 minutes with my teacher

  • @lukehardin9
    @lukehardin9 6 ปีที่แล้ว +122

    Literally the only good Mass Spec video on TH-cam

    • @haneenA.A.
      @haneenA.A. 5 ปีที่แล้ว +4

      Rlly?? I hope so. I decided to read the comments first then watch haha. I'm struggling big time with mass spec!!!

    • @Adecto
      @Adecto หลายเดือนก่อน

      Khan Academy is also great)

  • @Truck--kun
    @Truck--kun 6 ปีที่แล้ว +194

    *throws tuition at screen*
    why can't college professor teach this clearly!

    • @Mr.McMuffin
      @Mr.McMuffin 4 ปีที่แล้ว +6

      m8 I'm in 10th grade and I don't understand this at all

  • @wlo23ex81
    @wlo23ex81 4 ปีที่แล้ว +10

    Absolutely amazing. Until I found this video, I had so much trouble finding what the small peaks were, since I only found answers for the M+1 and M+2 peaks next to the molecular ion so I got confused if such isotopes were similar to the other smaller fragments.

  • @chymisttv7028
    @chymisttv7028 2 ปีที่แล้ว +2

    I'm Chymist, a final year chemistry student in Nigeria with a TH-cam channel called Chymist Explains. I'm inspired by Professor Dave Explains 🤗. He's my role model.

  • @1SmokingLizard
    @1SmokingLizard ปีที่แล้ว +5

    parents as chem teachers < your chem teacher < university chem teacher < some random YT tutorial < ChatGPT < Prof. Dave

  • @halasimov1362
    @halasimov1362 6 ปีที่แล้ว +4

    Wow I thought this was way beyond my comprehension but you explained it so well! Sparked fascination

  • @lauradc9036
    @lauradc9036 3 ปีที่แล้ว

    wish i'd known about you when i was in undergrad but now trying to review these topics for the MCAT it's been really helpful! thank u so much!!!

  • @a27670011
    @a27670011 2 ปีที่แล้ว

    thank you so much! this short video just helped me clarify the points that had confused me for a long time

  • @JoyceGem
    @JoyceGem 6 ปีที่แล้ว +4

    Prof. Dave, I'm taking Masters right now and we are self-learning these things. I'm thankful that you post videos on instrumentation. Perhaps you know how to teach us on method development? :)

  • @erin1427
    @erin1427 8 ปีที่แล้ว +11

    Just in time for the ACS exam.. Thanks Professor Dave!!

  • @livthomson7244
    @livthomson7244 3 ปีที่แล้ว +4

    Professor Dave is even better at explaining topics than Khan Academy! Currently studying for the MCAT and couldn't have raised my Chemical and Physical Foundations score without you!!

  • @philfaith9141
    @philfaith9141 6 ปีที่แล้ว +1

    I find your explanations so easy to understand. thanks.

  • @pabsz5903
    @pabsz5903 7 ปีที่แล้ว +15

    damn you explained this SO well, thanks man. Subbed

  • @engenheirometaleiro2268
    @engenheirometaleiro2268 4 ปีที่แล้ว

    You are so clear, i’m impressed, as always

  • @tenzinchoesang354
    @tenzinchoesang354 5 ปีที่แล้ว

    Thanks for the simple explanation, extremely useful for my school's assessment!

  • @megamale1000
    @megamale1000 6 ปีที่แล้ว +4

    Thank you this video helped immensely.

  • @wilt-read8988
    @wilt-read8988 5 ปีที่แล้ว +3

    YOU ARE THE BEST, THANKS DAVE

  • @ttwtt2488
    @ttwtt2488 7 ปีที่แล้ว +5

    This is perfect, thank you. Re-watching the youtube advert!

  • @omarhamza7738
    @omarhamza7738 6 ปีที่แล้ว +3

    Oh thank god for Dave. My Ochem 2 professor barely speaks English so this was very informative to me.

  • @laurensettle3899
    @laurensettle3899 2 ปีที่แล้ว +1

    Searched mass spec for dummys because i have to do a poster about it for an assessment, was not dissapointed.

  • @Nikkeishajk
    @Nikkeishajk 7 ปีที่แล้ว +33

    the opening makes me smile every time XD

    • @NewWesternFront
      @NewWesternFront ปีที่แล้ว +2

      i bet he did that on purpose to relax your brain muscles for the mental reaming of the content ahead

  • @christinaornelas6151
    @christinaornelas6151 7 ปีที่แล้ว +3

    This is incredibly helpful.

  • @itsmevien
    @itsmevien 7 ปีที่แล้ว +4

    thank you for the wonderful explanation! ur new fan from Indonesia~

  • @Hibyewt
    @Hibyewt 3 ปีที่แล้ว +5

    This was not confusing at all! Thanks so much. This helped explain things so much quicker, at least the basic concept. I feel prepared to continue further into the slides :X. I know I'll be one day able to make it into the veterinary science field!!!!! Thanks so much for your help Dave!

    • @zhibaniola6460
      @zhibaniola6460 2 ปีที่แล้ว

      can mass spectrometer identify the ingredients of coke?

    • @neithonosmani9783
      @neithonosmani9783 2 ปีที่แล้ว

      @@zhibaniola6460 I think you need to use both infrared spectroscopy and mass spectrum. Infrared spectroscopy to identify the type of functional groups. Maybe the ingredients can be identified if you know which ingredients have which functional groups I think?

  • @reidmcneil1212
    @reidmcneil1212 7 ปีที่แล้ว +49

    I learn way from you than my O chem prof who has a PHD in spectroscopy

    • @Mephiles550
      @Mephiles550 6 ปีที่แล้ว +19

      That fucker probably wasn't teacher material, just a guy with a PHD. PHD doesn't mean teacher. Shame college response to this is often just "Duuuh... wuh..?"

  • @armandomendez2613
    @armandomendez2613 5 ปีที่แล้ว +1

    Test tmrrw 😪 great video I probably learned way more than I need to know for high school

  • @frhneil1463
    @frhneil1463 2 ปีที่แล้ว

    amazing how much can be fit in 4 minutes. thank you so much !

  • @Aieshoo
    @Aieshoo 7 ปีที่แล้ว +4

    omg you clarified everything!

  • @julianp3385
    @julianp3385 7 ปีที่แล้ว +1

    Amazing! Keep up the great work! :)

  • @joshgeorge1714
    @joshgeorge1714 5 ปีที่แล้ว

    Great Explanation!!! Prof Dave

  • @orchalimsalam3275
    @orchalimsalam3275 6 ปีที่แล้ว

    Thank you ,it is very important and very clear tutorial

  • @francklatouche6143
    @francklatouche6143 ปีที่แล้ว

    Thank you so much professor Dave.You are amazing!👍👍👍👍👍👍👍

  • @7rfavelli719
    @7rfavelli719 11 หลายเดือนก่อน

    Great explaination. I already learned this but this video is great for refreshing props!

  • @kareemapbio7332
    @kareemapbio7332 4 ปีที่แล้ว +2

    Analytical Chemistry is so difficult for me but I find it the most interesting. Dream job, analytical chemist with a concentration in organic synthesis.

  • @divyanimishra42
    @divyanimishra42 8 ปีที่แล้ว +1

    Thanks Professor Dave

  • @saadarshad4635
    @saadarshad4635 ปีที่แล้ว

    Thank you so much Professor, this helped me alot for my chemistry class. Lots of love

  • @faiqaimran7890
    @faiqaimran7890 7 ปีที่แล้ว +2

    Thank you!

  • @TheTheaterThug
    @TheTheaterThug 7 ปีที่แล้ว +156

    Thanks Dave Grohl

    • @vasilikikatsouda986
      @vasilikikatsouda986 6 ปีที่แล้ว +4

      lol

    • @HScripturez
      @HScripturez 4 ปีที่แล้ว +1

      As a drummer, i am disappointed i didn't see it earlier

    • @a.od-reszki4674
      @a.od-reszki4674 3 ปีที่แล้ว +2

      I never thought that people who likes that music will whatch stuff like this (despite i like heavier things.. )

    • @austinlincoln3414
      @austinlincoln3414 2 ปีที่แล้ว

      Lol

  • @andrewprinn2548
    @andrewprinn2548 5 ปีที่แล้ว

    this is so much easier to understand than what my professor said. thanks!

  • @thabangncongwane1938
    @thabangncongwane1938 4 ปีที่แล้ว

    You nailed it Prof.

  • @aliarene
    @aliarene 3 ปีที่แล้ว

    Thank You Dave!

  • @JMSouchak
    @JMSouchak 2 ปีที่แล้ว +1

    I had to explain MS and the phrase I got from this video "vaporize it, ionize it, and smash it to bits" has been so helpful also it reminded me of the line "smash 'em, boil 'em, put 'em in a pot."

  • @grandpatouchy8675
    @grandpatouchy8675 หลายเดือนก่อน

    Thank you professor Dave!

  • @christophergoudarzi9992
    @christophergoudarzi9992 ปีที่แล้ว

    Very helpful, thanks so much!

  • @rokayaahmad7617
    @rokayaahmad7617 4 ปีที่แล้ว

    Great video prof thank you a lot

  • @ahmufamily5054
    @ahmufamily5054 4 ปีที่แล้ว

    Ok seriously. I should've watched this at the beginning of the semester :/ so helpful!!

  • @hananon23288
    @hananon23288 8 ปีที่แล้ว +107

    I click on ads for you because you're the best!

  • @apputhilak2473
    @apputhilak2473 6 ปีที่แล้ว

    Thanks dave so helpful for me

  • @CTimmerman
    @CTimmerman 10 หลายเดือนก่อน

    1. Heat up your mystery matter sample.
    2. Ion-thrust those molecules into a magnetic field.
    3. See where they land. Higher mass has lower deflection by the magnetic field.
    4. Compare landing spot hit ratio to known samples.
    5. Present list of likely ingredients of your sample.

  • @wk-pw7kj
    @wk-pw7kj 2 ปีที่แล้ว +1

    You are remarkable, thanks a lot

  • @albertf.9198
    @albertf.9198 5 ปีที่แล้ว

    Thank u prof dave, cool video.

  • @misslee4245
    @misslee4245 5 ปีที่แล้ว

    thank youuu.... keep it short and easy to understand is better

  • @sumaiyaislam1152
    @sumaiyaislam1152 6 ปีที่แล้ว +10

    thankuu sir ..ur way of teachimg is very amazing ..ur student frm pakistan :)

  • @katewaldie3473
    @katewaldie3473 5 ปีที่แล้ว

    10/10 explanation thank q dave!!

  • @catyy223
    @catyy223 6 ปีที่แล้ว +1

    Thank you soooo much! greetings from Germany!

  • @geetarani2875
    @geetarani2875 5 ปีที่แล้ว +1

    nice explanation dear sir

  • @pavithrag5513
    @pavithrag5513 2 ปีที่แล้ว

    This is the 1st time i'm watching your vdo. After watching this single vdo immediately i subbed and liked😊

  • @michealwaldrup4357
    @michealwaldrup4357 7 ปีที่แล้ว

    Great video! I would've liked some comment on the m+1 peak though, since we can gather some info on # of carbons from the ratio of the M+ and M+1 peaks. Still don't totally get that, but I know I'm supposed to be able to tell number of carbons from it. haha Thanks again.

  • @LedibelloLedi-hs3so
    @LedibelloLedi-hs3so 10 หลายเดือนก่อน

    Great explainer

  • @zeynepcokceken8429
    @zeynepcokceken8429 7 ปีที่แล้ว +2

    excellent!!

  • @mekdesbelete8766
    @mekdesbelete8766 3 ปีที่แล้ว

    well DONE

  • @freshtahs6555
    @freshtahs6555 3 ปีที่แล้ว

    this guy is the only reason I would pass chemistry this year

  • @Arya_Takeda
    @Arya_Takeda ปีที่แล้ว

    Your videos are saving my grades 6 years later. Thank you! 😂

  • @lakep7798
    @lakep7798 ปีที่แล้ว +2

    Professor Dave, you know a whole lot, but do you know just how many people you have helped understand these concepts and ace their courses? ❤‼️

  • @sweetsara060
    @sweetsara060 5 ปีที่แล้ว

    very helpful! THANK YOU (:

  • @minabish1783
    @minabish1783 4 ปีที่แล้ว

    Thank you

  • @jacquelinelabovitz4613
    @jacquelinelabovitz4613 6 ปีที่แล้ว +1

    you are amazing!

  • @taofang8463
    @taofang8463 3 ปีที่แล้ว

    Thx! Useful!

  • @user-qw6dy5tg8j
    @user-qw6dy5tg8j ปีที่แล้ว

    A shout out for your helpful explanation

  • @SweetChemistry
    @SweetChemistry 7 ปีที่แล้ว

    Thanks

  • @Justmyopinionlol
    @Justmyopinionlol 4 ปีที่แล้ว +1

    awesome thanks bruh

  • @KiriNini
    @KiriNini 6 หลายเดือนก่อน

    Thanks man

  • @sajanimalshaniamarasingha5482
    @sajanimalshaniamarasingha5482 ปีที่แล้ว

    that explanation is more effective sir. Please explain more advanced problems due to this part.

  • @zygaf6252
    @zygaf6252 6 ปีที่แล้ว

    Why isotope effect isnt observed on your spectra around m/z=72 peak?

  • @yikes9921
    @yikes9921 2 ปีที่แล้ว

    Thank youuu.!!!

  • @mitsoulas35
    @mitsoulas35 6 ปีที่แล้ว

    Professor Dave, what happens if you forget to put the anthrone in the blank?

  • @MissionHealth08
    @MissionHealth08 3 ปีที่แล้ว

    How to identify and quantify different valency of particular element?

  • @TALKyLIKEENGLISH
    @TALKyLIKEENGLISH 2 ปีที่แล้ว

    Prof, what about little peaks around 29 au peaks, and more than it?

  • @AnkushSharma-zv5hv
    @AnkushSharma-zv5hv 6 ปีที่แล้ว

    thanx bro...

  • @indukumarimurugan7639
    @indukumarimurugan7639 7 ปีที่แล้ว

    what about C+ and H+ fragments

  • @nnataliered
    @nnataliered 6 ปีที่แล้ว +2

    damn I just learnt this in such little time and my teacher couldn't even teach me in a week XD

  • @Spectrometer
    @Spectrometer 4 ปีที่แล้ว

    Your explanation is good but it only accounts for qualitative organic analysis. Mass Spectrometry not only serves to identify molecules but also, for example, counting metal ions in water (ICP-MS, IC-MS, etc.).

  • @rabbanisumra7914
    @rabbanisumra7914 6 ปีที่แล้ว +1

    is it possible that elements also gets seperated ie Hydrogen and Carbon, or just whole molecules will only gets ionized ie CH4?

    • @orca_ah
      @orca_ah 4 ปีที่แล้ว

      yes, it is possible, those small peaks could also result from separation of H atoms

  • @km2052
    @km2052 5 ปีที่แล้ว

    thx

  • @sneedle2316
    @sneedle2316 ปีที่แล้ว

    gordon doesn't need to hear all this he's a highly trained professional

  • @chris2656
    @chris2656 4 ปีที่แล้ว

    why do the smaller peaks appear at lower points on the line? Shouldn't they have a greater molecular mass if they correspond to c-13 or H-2 isotopes?

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  4 ปีที่แล้ว

      hmm well it depends on the specific combination of nuclides i suppose, but yes generally we see n+1 peaks very commonly, for one instance of C13 in the molecule for example

  • @Koleys
    @Koleys 2 ปีที่แล้ว +3

    I just started an analytical job, and the chemist I’m shadowing tried to explain this to me over the course of 3 hours. I was so overwhelmed because when I learned this is university I used professor Dave’s videos and aced all my exams. But now I’m working with cannabinoids for the first time, and the computer does the majority of this work for you.
    I’m even more confused now. Sometimes the computer finds a 90% match and we are told to always stick with the computers choice if it’s above an 80%.
    If it’s below we’re supposed to just compare NIST charts to our results and determine to the best of our abilities.
    There are about 400 cannabinoid terpenes, and I genuinely don’t know how to approach my job compared to university work.
    Should I go off and study the NIST charts? Should I just give it time and learn as I go? I’m so lost and everyone I have shadowed at work has been with the company for 4+ years. They suck at teaching because it’s second nature, but I’m not sure how to configure work life. I’m so used to cramming and studying until 3am for lectures.
    Do I study for work? Or do I keep myself sane?

    • @NewWesternFront
      @NewWesternFront ปีที่แล้ว

      how's it going

    • @CTimmerman
      @CTimmerman 10 หลายเดือนก่อน

      So you have to manually compare 400 charts to your sample? Doesn't the computer do that for you?

    • @wolfrahmphosphoros5808
      @wolfrahmphosphoros5808 3 หลายเดือนก่อน

      bloody hell, I'm so sorry. regards.

  • @onlineberuska9867
    @onlineberuska9867 5 ปีที่แล้ว

    Hi Dave, which machines are you using, and find most useful? Analytik Jena, Agilent, Bruker or value scientific? Keen to hear your thoughts on each .

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  5 ปีที่แล้ว

      oh man i don't remember at all! last time i used them was in undergrad which was 14 years ago.

  • @infinity-and-regards
    @infinity-and-regards 7 ปีที่แล้ว

    Is it also possible to break C-H bonds and see loose hydrogens on the spectrum? By the way, your videos are greatly appreciated, thanks Prof.

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  7 ปีที่แล้ว +4

      hmm, i suppose? not too sure! i know usually it's carbon skeletal fragments

  • @siddas9124
    @siddas9124 6 ปีที่แล้ว +1

    Perfect

  • @lemao9995
    @lemao9995 4 ปีที่แล้ว

    thnx homie

  • @billygraham5589
    @billygraham5589 5 ปีที่แล้ว

    I give a thumbs up here, and I don't give those to just anybody for any video!

  • @sihammirdad1801
    @sihammirdad1801 7 ปีที่แล้ว

    ?what about aromatic benzene compound? how to fragment

  • @inarmi7169
    @inarmi7169 5 ปีที่แล้ว

    awesome!

  • @hanifnada17
    @hanifnada17 6 ปีที่แล้ว

    Can you explain about M+1 that use for calculation?

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  6 ปีที่แล้ว +1

      if i remember correctly this has something to do with isotopes, like the relative abundance of C13 in a compound

  • @asifalamjoy9530
    @asifalamjoy9530 5 ปีที่แล้ว

    Why vaporisation is necessary ?