This, for me, is the ultimate answer to my chronically severe neurological, cardiovascular, cognitive issues and so much more ; all of which I very strongly assert are related to statins therapy. Two years keto reversed T2 diabetes and digestive issues but stopped working and same with two years carnivore. Developed heart issues and chronic fatigue left me in bed constantly. Couldn’t walk due to dizziness/disorientation/nystagmus. Scans revealed widespread demyelination in brain and spinal cord sheath. The palpitations, muscle twitches, extreme fatigue and weakness were overwhelming and I truly felt I was dying one cell at a time. The rollercoaster of psych symptoms no joke either. Went from loving life extrovert to fearful recluse. Oh and the pain…the pain in muscles, bones, ligaments and joints was unrelenting. Developed meat aversion but still craved fat and connective tissue !🤷🏽♀️ Most carbs caused pain and swelling in abdomen and joints and immediate crash needing to sleep . Breathlessness and severe sleep apnoea persisted. It just goes on. Anyway, found this amazing channel and tried 500mg B1 initially but no noticeable improvement. Added B complex and Amino acids complex. Started to feel almost human again but still chronically fatigued, postural dizziness, heart racing. Increased B1 to 500mg x 3 daily and wow! Balance problems gone in a couple of days. Cognitive decline improves daily. Added taurine, CQ10 and magnesium LLM1, d3MK7 and this stack after 30days approximately has been life restoring. I can’t thank EO enough for this priceless information and his willingness to share it. I dread to think what would be for me without his help THANK YOU 🙏🏽 ❤
@@bartginger123 B1 500mg (thiamine HCL), from Amazon UK. I have tried other forms and they don’t seem to provide me any added benefit and are more expensive. No sleep disturbances.
@@jennygibbons1258 Thank you so much for your reply. I was reading your experience again and it's really incredible! I have abdominal bloat and swelling from gluten & dairy (not sure about carbs in general). I get fatigue and insomnia, as well. Do you mind if I ask how much taurine and CoQ10 you take (and what time of the day)? I've never taken an amino acid complex and suspect I should research those, also. I am so glad you commented here a while back and shared your personal experience. So helpful! 🙏❤
@@bartginger123 I have to admit I struggle with consistency. However, I try to remember to take taurine twice daily, the second dose no later than 3pm coz I don’t want insomnia. I have had to trial and error to find my own baseline that is both effective and sustainable. I have also learned to be prepared to readjust because my body gets used to things and sometimes what worked for a while just stops working. I have learned to scale up or even down to see if it helps and this is why it’s so important to be your own advocate and do personal research. Hope this helps
00:10 - Summary of examining what sort of symptoms someone experiencing thiamine deficiency. What are some of the causes of why people develop this deficit? And if carnivore or keto diets are sufficient for addressing this deficiency? As well as some case-studies regarding people on keto or carnivore diets that they didn’t see results on that diet until supplying thiamine at high doses. 01:01 - The many signs of thiamine deficiency are GERD [gastrointestinal esophageal reflux disease], bloating, constipation, delayed gastric emptying, gastroparesis, visceral hypersensitivity, undigested food in stools due to lack of pancreatic enzymes from low stomach acid, gut pain, dizziness, POTS [postural orthostatic tachycardia syndrome] & visual disturbances, low/unsteady blood pressure, tachycardia, central fatigue or systemic fatigue, fibromyalgia, chronic fatigue syndrome, carbohydrate/alcohol intolerance, neuropathy/pain tingling, poor temperature regulation, insomnia, low/high appetite, inability to gain weight, Raynaud's/poor circulation, EMF/light sensitivity, brain-fog/anxiety, breathlessness or air hunger, sleep apnea, etc.) 03:44 - The real pioneer of this therapy is Dr. Derrick Lonsdale, part in due to research done in Japan. He found benefits by pioneering research in the Cleveland Clinic to treat autonomic nervous system dysfunction, autism, ADHD, behavioral & neuropsychiatric disorders, chronic fatigue syndrome, post-viral fatigue syndrome, etc. All with Thiamine. 04:32 - What you really need to know is that the more glucose you need to process the more thiamine you will need. Because thiamine is absolutely critical for glucose metabolism and fatty acid metabolism. This is through glycolysis generating as a co-factor for the enzyme called pyruvate dehydrogenase. It is also a co-factor in a process called the Kreb cycle, which is the next stage in how we are deriving energy from various food components. Thiamine is necessary for glucose and fats, and proteins for energy as well. 05:15 - Some of the other main functions is that it’s a co-factor for many other enzymes such as for Anabolic Reactions such as the Pentose Phosphate Pathway used to regenerate glutathione to protect against oxidative stress, and also how we synthesizing macromolecules such as fatty acids to make myelin sheath (antioxidant system, nucleic acid synthesis, fatty acid synthesis). Furthermore, thiamine is central in how we are breaking down certain amino acids particularly from red meat sources or sources that contain leucine, valine, and isoleucine, so how we are breaking these down is relying upon a thiamine dependent enzyme, this falls under Branched Chain Amino Acids (energy metabolism, cholesterol synthesis, neurotransmitter synthesis). Likewise, how we are taking certain odd chain fats and running them through a separate phase of breakdown called Alpha Oxidation is a fairly new established function of Thiamine known as Odd Chain Fatty Acids ( Acetyl-CoA, etc. Energy Metabolism). 06:30 - Aside from its role in processing macro-nutrients, it's also central in the nervous system. In fact, a thiamine deficiency primarily affects the nervous system or affects the nervous system first of all. It is needed to synthesize the neurotransmitter acetylcholine and also glutamate and the inhibitory neurotransmitter GABA. Furthermore, neurons utilize thiamine in how well they are able to regulate the various ions across the plasma membrane. And then we are using it to maintain and build myelin sheath. And actually, one of the forms of thiamine is necessary or seems to be necessary for how we are conducting nerve signals transferring information from one neuron to another neuron. 07:21 - There are certain areas of the brain which are particularly sensitive to thiamine deficiency, and this is because they have a very high-rate of oxygen utilization and energy metabolism. And these are the lower portions of the brain referred to as the brain stem, mamillary body, cerebellum, hypothalamus, thalamus, etc. Interestingly these parts of the brain are primarily in control of the autonomic nervous system, which is divided up into two main branches. The sympathetic [fight or flight] and parasympathetic [rest & digest] nervous system. And what this is essentially doing is it allowing us to adapt to environmental changes or environmental stimuli via controlling those involuntary processes that we don’t need to think about [body temperature, digestion, heart-rate, constriction and dilation of our blood vessels, etc.] and when we are thiamine deficient, these areas of the brain and this area of our autonomic nervous system are most affected. And we can end up with dysfunction in this area of the brain which creates dysfunction in the entire nervous system, as we begin to fail to adapt to environments appropriately. Essentially losing anti-fragility in the process due to having all types of misfiring by being thiamine deficient. 08:52 - Lonsdale characterized high-calorie malnutrition. This comes down to an up-regulation of macronutrients (refined fats, refined carbs, reined proteins) and down-regulation of micronutrients (vitamins, minerals, other nutrients). And as we consume too many refined macronutrients we deplete ourselves of micronutrients which leads to many of these disorders listed above. This excessive intake of glucose without adequate levels of co-factors that thiamine and other vitamins and minerals provide lead to sub-clinical deficits that leads to all sorts of a constellation of symptoms as illustrated throughout this video. Thiamine is particularly necessary for the appropriate metabolism of carbohydrates in particular, so those diets higher in carbs especially refined ones as you see with Dr. Ray Peat will require the higher need for thiamine and its cofactors, B-complex, magnesium, and potassium. 11:06 - Based on this concept previously spoken about here. The autonomic nervous system is in control of things like blood pressure, gut motility, body temperature, constriction and dilation of blood vessels, and those parts of the brain are also in control of appetite, and nutrient partitioning. As we can see many of the symptoms can be linked back to problems with the autonomic nervous system which is linked to thiamine deficits. 11:42 - Some primary risks are heavy alcohol use, whether binge or chronic use. High sugar consumption, white rice, refined carbs (bread, grains, etc.). Chronic digestive issues IBS-C or D, or A, diarrhea, constipation, etc. High activity stressors: athletics, workload, family breakup, or trauma. They tend to be Doers, so go-get-'em attitudes tend to lead to a crash due to thiamine depletion, this is partly due to ramping up the metabolism which requires a greater need for micronutrients like thiamine and its co-factors. Pharmaceutical Rx like diuretics or antibiotics (metronidazole) also induce deficits in thiamine which cause thiamine-wasting. Surgery/viral or bacterial infections low-grade or otherwise. 14:30 - After crashing from one of the above, generally you will see further carbohydrate metabolism and alcohol metabolism intolerances. Nervous system collapse, on fire, or chronic fatigue. A negative response to B vitamins & sometimes magnesium. Slight improvement on keto/carnivore diets but about 50% or so, this is because there is less requirement for thiamine on these diets. However, this doesn’t mean to stay on these diets as it doesn’t address the deficit but buys time. Neurological cardiovascular and/or digestive symptoms. Insomnia or not feeling rested after sleep. These all can drastically impact overall well-being and make it difficult to discover how to recover from this deep thiamine deficit. 17:10 - It is important to note that in opposition to the conventional way of viewing disease. Elliot Overton likes to look at it as a Spectrum of Severity. A conventional medical physician sees it as falling in the box of health or disease. But there is a large grey area in-between. Someone could be moderately healthy, but still, have moderate insufficiency, and they could develop a deficit of thiamine or other micronutrients as they gradually develop this deficit. But because they do not fit the diagnostic of a full-blown disease medicine dismisses them because they don’t fit diagnostic criteria. Which makes people ignore subtle sub-clinical deficits for long periods of time which can wreak havoc or lead to the straw the breaks the camel's back as it were.
18:15 - The Crash or Trigger is usually the straw that broke the Camel’s back. Metabolic stressors (trigger) are often from a chronic insufficiency minor or few symptoms and on the timeline, a Crash & Metabolic Shift can occur with multiple symptoms manifesting due to enzymatic down-regulation. It could be a loss of a loved one, car accident, surgery, excess food shifts, loss of a job, etc. So this acute event usually sends someone over the edge which shifts someone’s metabolism as they begin to develop symptoms they never had before, which seemingly randomly comes out of nowhere. And in the literature, it shows that actually people who are deficient in certain nutrients like thiamine, then the enzymes that use this nutrient you’ll see down-regulated which creates this enzymatic down-regulation which has to do with a sudden onset of symptoms out of nowhere that relied upon those enzymatic processes. 19:46 - So if we look at the full-blown deficiency of thiamine you find Berberi & Wernicke’s Encephalopathy. Which usually requires 100-1,000mg of thiamine per day independent of a healthy diet. Therapy may be necessary for 6-12 months to achieve full-blown remission of this disease. And carnivore and keto diets may simply reduce symptoms but ultimately you want to restore carbohydrate metabolism. And this is more evidence that diet alone is simply not enough. The RDA for thiamine is currently only about 1-1.5mg a day. 21:33 - Case Study 1. Male mid-twenties with a Medical history of {Neuropathy, Severe Constipation (once every 2-3 weeks), GERD & constant bloating, Severely underweight 116 pounds [53kg] at 6 feet tall and inability to gain weight, Unexplained low blood pressure, Autoimmune issues, Extreme fatigue, dizziness, breathlessness, and low blood pressure}. This client has had a very high and long consumption of white rice as a staple in his diet. And he has his Trigger being hospitalized 10 years prior. He tried multiple diets, even a strict PKD Carnivore diet for around 6 months, which helped with autoimmunity but not most of the other symptoms. He saw Elliot’s videos and got in contact with him. As he looked at it, he had this individual take TTFD (bioavailable thiamine titrating up to 150mg a day), high dose B complex, vitamin C, and magnesium malate. 24:28 - After an 8-week follow-up after one day, daily bowel movements. GERD, bloating, and indigestion almost disappeared after a few weeks. Gained 17.63 pounds (8kg) for the first time in nearly 10 years. Enjoys working out and is building muscle rapidly. Fatigue improved greatly, with no daytime sleeplessness. Overall immune symptomatic improvement in a short time frame. This all changed with just the suggestions of TTFD Thiamine with the co-factors listed above. Just another example of how some simple changes can drastically alter someone’s life. 25:39 - Case Study 2 Male mid-twenties with a Medical History of {Severe fatigue, and mental sluggishness, depression (feeling dissociated from the body), Chronically cold, and poor circulation, Chronic burping, and bloating, poor gastric motility (explaining that it felt like a rock was in his stomach) & constipation/loose stools, Terrible recovery from exercise, Previous neuropathy, palpitations (cardio abnormalities) and twitching. 27:07 - History continued: Long consumption of white rice/bodybuilder diet & alcohol during university. Antibiotics & infection trigger. Lost tolerance to carbs, coffee, and alcohol. Multiple variations of keto/carnivore for 18 months with some improvement, but still struggling. 27:54 - Lab work CBC + CMP Unremarkable. Organic acids (after a few weeks of B1 therapy). A slight elevation in lactate (related to low thiamine), 2-hydroxyisovaleric acid (BCKDH marker) [marker related to branch-chain amino acid metabolism]. Minor elevations in oxalate markers. 28:27 - Glycolytic Cycle Metabolites Lactic acid 22 High (acceptable reference range 0.74-19.0). Amino Acid Metabolites 2-hydroxyisovaleric acid 3.1 (acceptable reference range 0.41 or lower). Oxalate Metabolites Glycolic Acid 111 High (acceptable reference range 18-81). 28:42 - Therapy Worked up to 500mg TTFD Thiamine w/ Magnesium malate (he got worse initially, then got better, as this fluctuates due to increasing metabolic machinery to adapt to thiamine levels rising so titrate gently). With every subsequent increase in the dose, his symptoms got worse initially then better. Body heat increased like a furnace. Periods of feeling euphoric, better concentration, and energy. Bloating, burping, and digestive system made major improvements. Sometimes it can take 6-8 months to recover the machinery necessary to restore health from chronic thiamine deficiency. 30:02 - Case Study 3 Male early-twenties with a Medical History: Trigger - early stress at 10 years old, and he binged eat sugar as a coping mechanism leading to a bout of severe constipation. Gradually he developed the following symptoms. Burning mouth, feet, neuropathy. Severe SIBO, GERD, bloating, and slow motility + laryngopharyngeal reflux. Severe fatigue, poor temperature regulation, and no libido. Excessive salivation in the mouth, dizziness, and balance problems. Chronic pain, visual disturbances, etc. 32:00 - History continued. Tried almost every diet. Got worse with carnivore/keto & restrictive diets. Learned of thiamine deficiency, took benfotiamine before the consultation. Benfotiamine improved dizziness, and balance almost immediately. Saw Elliot’s videos and got in contact. Elliot doesn’t generally use benfotiamine versions, but the client noticed a difference with it at just one capsule a day. 32:44 - Therapy: Increase benfotiamine to 250mg 4 times a day. B complex, riboflavin & magnesium, etc. A gradual shift from benfotiamine to TTFD version of thiamine. 33:33 - Results after a few weeks. An increase in benfotiamine caused temporary improvement then worsening in symptoms. Shift to TTFD 300mg a day. Now able to say many different foods - meats, veggies, etc. within about two weeks on TTFD version of thiamine. Also able to exercise. Reflux completely disappeared, bloating/burping 70% improvement. Upper GI motility restored - bowel movement twice per day. Libido returned. Fatigue, LPR, and salivation still present. Early days. [My added suspicion might be sulfur metabolism issues with the benfotiamine version?]. 34:21 - Case Study 4. Female mid-60’s with a Medical History: Air hunger and breathlessness with fatigue. Unexplained low blood pressure and high pulse rate. Central sleep apnea, and dizziness. History of metformin use (thiamine depletion). Elliot speaks to this case to illustrate how one single deficiency can manifest as several different symptoms. 35:53 - Therapy before coming to see Elliot: Self-prescribed 900mg benfotiamine and 600mg sulbutiamine, B complex and minerals, carnivore diet. She noticed little change in fatigue but a big improvement with air hunger and breathlessness. And her pulse rate balanced and her blood pressure balanced fast. When she doesn’t take that dose these symptoms return. 36:53 - Central sleep apnea is another one of those unknown symptoms of a thiamine deficit, related to oxygen deficiency in the brain. 37:04 - Thiamine Deficiency Disease, Dysautonomia, and High-Calorie Malnutrition by Derrick Lonsdale and Chandler Marrs. How to address this issue in more depth get this book! 37:48 - Next videos Clinical laboratory indications of thiamine deficiency. Are there lab tests available? Which labs might indicate a deficiency? Which is the best form of thiamine to take? What is the difference between the forms of thiamine? Which health conditions might benefit from which form?
Hello Dr. Brandon I have a question how do we test the thiamine deficiency ? I am a crossfiter and later I do suffer from chronic fatigue....I appreciate the video I think you nailed my problem.
Brandon, your time stamps are super helpful and much appreciated. If there is a way to follow you, I will do my best to find it. Thank you for your time and effort.
I'm 54 and have had these problems for 20 years and now getting to the stage where I don't really leave the house. Depression chronic fatigue and sleep apnea are pushing my hope out the window. I have ordered your B1 thiamax and praying to God if there is one they work for me. Thank you for your video's
I'm pretty happy with Benfotiamine. I take around 450MG (16th of a teaspoon) 2 to 3 times a day. It has literally changed my life. It took 4 months at first because I was taking too small of a dose. Hang in there and give it some time. I also had food sensitivities. Had to give up high nickel foods and all milk products 😭, but that cleared up my flu like pain.
You may also want to try Now 1000 mg NAC with Now glycine. The powered is cheaper than the pills. I have a goal of 100mg per kilogram to reverse aging. Look up GlyNAC.
Remember that Elliot recommends several cofactors, including vitamin b2, b5, b6 (in nicotinamide form), magnesium (in whatever form you can tolerate best), coenzyme q10, and a few others depending on your issues.
Elliot! I’m so glad to have discovered you! I was struggling with vertigo/dizziness/balance issues for some months since August. Went to a neurologist and an ENT. (I’m 77, have hearing loss, wear aids since childhood) and suffered vertigo once in a while through the years, especially after stressful situations. The neurologist ordered an MRI which I had done Dec 1. Still not told outcome of that. At any rate, after learning about Thiamax, I thought I would give it a try. I take one every day. Right away I noticed the weirdness of my off-balance “dizziness” was gone. No problems since! Thank you, thank you.
It's a miracle this video randomly popped in my newsfeed & my landed right at the top comment, which is yours. I had two acute bouts of vertigo last year that were terrifying. The first one hit me in May and after that the brain fog, balance issues & mild nausea have never left. Going to try thiamine now. 🙏
@@richardk5246 Brain fog and head pressure are much better, but not gone. I'm also taking an antihistamine every day and will for a month. The improvements are welcome, but I'm not yet cured.
Excellent video. Thanks a lot for this. I supplemented B1 after being on keto/carnivore for 8 years and felt like i have a new mind/body. Most particularly, my digestive symptoms, irritability, and fatigue have improved remarkably.
I understand that entirely. Is it worse for you depending on the weather? I can't handle very hot weather. Couldn't breathe outside yesterday. I ended up fainting, decided to go inside and sleep.
I developed air hunger consuming for 1,5 year to much alcohol! It is terrifying! Alcohol depletes vitamins and so on. So b vitamins too among others. No oxygen enough in your cells ( mytochondria ).
I've spent 2 days down a rabbit hole listening to you, looking up taurine, thiamine benefits.Currently stacking B1 800mg (working up to 2000mg), B12 4800mcg, MCT powder. I'm so chilled😏 I'll add taurine. You Rock!!!
I have had fatigue, dyspnea, panic attacks, chronic constipation, bloating, food sensitivities, anxiety, and general inability to deal with stress for over 4 years now. I tried many things and nothing worked. It was causing me more stress and I was in this vicious cycle non-stop. What you say makes total sense. I have started low dose thiamin with magnesium and I'm already seeing positive results. I will move on to high dose thiamin and actively try to eat thiamin rich foods. I can't thank you enough for putting this information out there.
Hey there, I've struggled with loose stools, gas, fatigue, carb intolerance, and inability to recover from exercise for roughly two years. Symptoms developed when I was doing a lot of exercise (3-6 mile runs every day with weight lifting every other day) and then had covid followed by a course of antibiotics for an infection. For the last 6 months I had to refrain from exercise completely because I could not recover at all. I recently started an animal based diet along along with magnesium supplementation (400-600 mg of malate and glycinate a day) two months ago. I did have an improvement in symptoms but improvement plateaued. 4 days ago I started TTFD and I've already had some huge improvements in fatigue and carb intolerance and a decrease in gas. My energy is improving daily and I think I might even be able to return to exercise soon. I am feeling more like myself than I have in the two years since this began. I am now suspecting I actually had developed gastrointestinal beri beri. However, I have so far had not much improvement on the loose stools. In your experience, how long does it take to resolve GI issues once started on TTFD with cofactors? Thank you so much for your videos they have been incredibly helpful and offered a lot of hope to me in recovering from this.
Hello, I think I may have over-exercised my way into a deficiency as well. Since the start of covid, I have been getting at least 15000 steps a day as well as lifting weights 4-5 times a week. On top of that, I have also been intermittent fasting for about 16-20 hours a day. I recently started at a does of benfotiamine, 300 mg per day, did you start TTFD immediately or did you have any other forms of B1 prior?
Got 95 % of those symptoms. No doctor ever head a clue and been suffering for decades. Thanks for researching in this field so ambitiously. Started to change my diet towards seeds, nuts, legumes etc. and taking Thiamine HCl in a moderate dose. Also avoiding caffeine, sugar and alcohol.
@EONutrition Your work truly is fantastic. This is GOLD. I'll keep making notes as time permits. Hope you enjoy the time stamps. I am sharing your work on all types of forums so hopefully, you'll get some additional clients from all this.
Elliot, I wanted to share personal experiences mentioned in Case 3, the burning throat, and for me mouth and tongue. We we're inhaling methanol in Pulp Mill Emmissions building an Air Emissions Project beside a operating Pulp Mill. My last 3 days my body was like a piece of lead (hypoxia). There were 59 tradesmen on oxygen at the Hospital the 3rd day, and that evening I had the burning throat issues. I avoided Pulp Mills for a year and then got gassed again at another site! Vehicle exhaust started on-setting the same sequelae of symptoms as the year before, cardiac issues and the burning throat... learning there is formaldehyde in vehicle exhaust which metabolizes to Formic acid in the Liver then Lactic acid cellularly driving FM pain! It is the elevated Formic acid which causes the burning throat. There are also elevated levels of Aldehyde in E85 ethanol entrained Gasolines, being the hangover component of legal drinking alcohol, thus can lead to Thiamine deficiency for daily commuters. Assuming this young man also jogged on busy streets, he may have been inhaling Aldehyde. Then there is the soda drinks with an artificial sweetener derived from formaldehyde. There are Environmental complexities that affect our health. We we're also inhaling Aldehyde and Potassium, but that can be shared later.
Case studies are so helpful. This is incredible. I’ve had increased sensitivity to coffee, going to remove from diet and supplement bentofiamin for a while.
I'm a poster child for the Risks or Triggers and the After Crash pages. This happened when I was 8 and I've been struggling since. Up and down and finally into disability. Intolerant to alcohol, low HR, low BP, etcetera, inability to process carbohydrates (put on weight looking at food - yet, at my sickest I went from putting on weight to dropping weigh precipitously only to put it on again with the next big crash), no stamina and eventually a ME/CFS diagnosis. Couldn't handle folate (e.g, magnesium eventually helped me do that). Partial improvement on a keto like diet years ago only to go down hill again. Diet alone doesn't do it. I've been eating a fabulous diet most of my adult life because I'm not well and I'm sensitive to so many additives that I eat whole foods and it's rare that I consume a processed food. Also, I just crashed more after the Covid Vax, and reactions to vaccinations seem to put stress on thiamine for some. (BTW, for whatever reason, I don't deal with tachycardia any more, but that might be that I'm getting enough thiamine to knock that out.) I think my health crashed at 8 because I'd stopped eating breakfast and lunch at age 6 (had a parent who wasn't paying attention and I got the message that I wasn't deserving of care) and then in year 7 had a lot of challenges to my health, including two severe infections, one emergency room grade fever, and surgery. My health turned a corner for the worse. Then, in my teens, doctors prescribed antibiotics for acne. I was on them for 5 years. Goodbye any chance at health.
Holy crud... nutritionist just recommended benfotiamine. I have every symptom. Mind blown. Starting tomorrow... hope I can start eating again and gain weight. Worst symptoms are aversion to food/ even water and psychosis. Carnivore diet has helped immensely but this is the missing piece. Thank you for the information.
Crazy year... so much better. I was very, very ill. I believe high dose thiamin caused some damage, however, as it induced magnesium deficiency. I was definitely deficient, but balance is key in healing. Grateful for the journey
Great video, a lot of these symptoms dovetail with mine. Especially the crash thing. I also have mthfr, I am not sure on how that effects supplementing b1. But I did read in some of your comments that it can have extreme effects on anxiety. Some of the anxiety, panic attacks, while having a migraine and heart palpitations are things I’m looking to a avoid experiencing again, at all costs. I have been dealing with autoimmune problems (psoriasis) that have stemmed from a tooth infection I didn’t know I had. I can’t afford the surgery and it’s been hard to work with all these symptoms on top of the extreme life challenges that have come my way in the past few years.
Thiamine deficiency is what made civilization. Grains deplete it, changing the gut flora to make more nervous and hyperfocused (mildly autistic) humans who are afraid to stand out. Conformity. Specialization in the division of labor.
I'm autistic and most autistic people I know have no difficulty with conforming. We, more often than not, don't conform or value conformity. I don't see a lot of people being hyper-focused out in the world.
This is exactly what's happening to me. Concussion, father's suicide and loss of relationship all within a three month period, I feel like my entire system is constantly inflamed.
Great content!, From informational standpoint I'm curious, if therapy to resolve a defficiency does need lifelong supplemental support or can therapy be stopped when the symptoms resolve?
I assume it depends on why each person got too low. If it is still an issue I would think you always need help. If you are getting enough nutrients and know you can absorb them, you can just focus on nutrition. Not sure
20 + years insulin resistance at a lower weight to most diabetics...Many incidences of antibiotics due to undiagnosed hidrodenitis suppurativa inflamation.. many years of 5+ coffees a day, Drink way too much sugary wine when im not sticking to low carb.. alcohol tends to go right through me though. makes me shit water for a day. Active physical job and generally fit for a 40 something year old. . Improved many other things greatly on keto and zero carb diets over the last 3 years.. lost weight levelled bgl, stopped asthma depression etc... still suffering from occasional feet pain and swelling and hand and arm numbness and palps. CAnt lose weight aymore no matter what i do. Always assumed B vit deficiencies were a vegan thing. Starting to feel like I'm text book thiamine def the more i watch your vids.
I actually developed hypokalemic periodic paralysis without the genetic variants due to thiamine deficiency. Also hyperadrenergic POTS. The POTS started with me passing out behind the wheel of the car. I had already been Dxed with non-celiac gluten sensitivity a few yrs before with the undigested food diarrhea but I was still on a low carb diet. Had a very high viral load, do too. Never drank alcohol. It’s scary how far down the road towards death you can get if the problem is a primary nutritional deficit. No one really figured this out-YOU saved me Eliot. Once an emergency MD ruled out one thing and checked my Mg level, I extrapolated that thiamine and zinc deficiencies would follow. That’s when I found your channel. I actually do have an acute hepatic porphyria and Ehlers-Danlos type 4, but the deficiencies were so severe that the symptoms confused everybody. My thyroid is still screwed up, and other things too-pancreatic insufficiency (fat malabsorption), bone fragility, mold exposure...it never ends.
@@EONutritionwhy is it you think some just some with some of these nervous system disorders heal completely with brain retraining? Just curious your take on this?
Continuing to binge watch your videos and others related to Thiamine deficiency - have tried just about everything else. Not sure how or why your vids finally started appearing in my feed, but I have been on Optimal Ketogenic Living, Root Cause Protocol, Vegan, Vegetarian, Hallelujah Diets, Weight Watchers, etc. I think the only video I got a clue on was when Mary Ruddick was being interviewed by a Carnivore doc - fell in love with her.....she has the brightest affect of just about anybody I've seen lately....she mentioned that the Carnivore Way of Eating might be deficient in Thiamine....so..... The recommended book by Lonsdale and Mars is way too pricey for me, even on Thrift Books....a matter for prayer. I did order what I thought was Allithiamine from Amazon, but the label I got was All Thiamine - it says it TTFD. So, have ordered some Thiamox.....hope it's the real deal. Also using a B-Complex from Desert Harvest without B6, since my hand neuropathy got so much worse after trying to treat "Pyroluria".... Thanks for all your work, and putting the info online.....I and my family-of-origin/family-of-orientation pretty much textbook cases of Thiamine Deficiency......
CFS carnivore here. Took first does this afternoon, feeling much better. Brain fog gone, and much more mental energy. Horrible day turned better. Took B active multi, which has 100mg HCI, and separately Allithiamine 100mg.
I started high dosing ( started w 500 mg thiamin hcl BID) and had to quit strict carnivore ( went to carnivoreish, added a serving of fruit each day) because it induced oxalate dumping and tanked my potassium levels. I also upped my potassium, and other electrolytes, and reduced to one B1 serving per day to reduce the oxalate dumping ( and added vit c to reduce oxalate dumping, among other needs) and found some relief. Carnivore alone still left me w POTS and CFS.
You need to go to a clinic and get vitamin B shots. I've been on carnivore diet for a couple of years. Been pretty strict except for protein shakes I take twice a day. I also supplement with B vitamins, NAC, zinc carnosine, and pink bark extract.
How long were you carnivore before starting the thiamine? You started with a large dose it seems. I’m going to start tomorrow with a lower dose hopefully it’ll be easier. I’ve been carnivore 9 months.
This is me. For years. Pretty much since a young teenager & i’m now in my 60’s. Fatigued. Always tired. No motivation. Lethargic. Can’t tolerate alcohol. Never have restful sleep (when I can sleep). Struggle to lose weight other than VERY low calorie. Digestive issues for years culminating in almost total collapse. Can no longer digest/process animal protein. Did Keto/carnivore for over 8 years but only ever gained weight & it did nothing for my fatigue. Very slow digestion. Diabetic & cannot seem to reverse it regardless of what I try. Parasites I cannot overcome (they contribute to the nervous system stress - my nerves are so sensitive I can feel them constantly, more so at night, which contributes to the insomnia - I want to sleep but they give me no peace). I used to have GERD & a hiatus hernia, years of IBS, palpitations, neuropathy & high blood pressure, but dumping wheat, most sugar & pasteurised dairy managed to calm that down. my body feels very acidic (Lactic Acid). Osteoporosis. Periodontal disease I cannot seem to reverse (the acidity pulling alkaline minerals out of my bones, teeth & gums?). Chronic hair loss. Vision loss. Oh & did I say? Tired. All. The. Time.......
Try intermittent fasting. And take vitamins and minerals daily, it's very important. Taking vanadium and chromium are vital for reversing diabetes. AND stop eating process foods, if it comes in a box and says natural it's not real food (bad for diabetes! ) you should be able TO SEE natural food 😉
This video is a game changer. I have a ton of these symptoms. You have singlehandedly given me HOPE! My concern is this: you said that when people stop taking thiamine... the symptoms return...! What is the root cause here?? Any suggestions? I just bought some thiamine but will order yours from Amazon this week. Thank you for what you do. Truly! 🙏
Thank you elliot, you advice has really helped me combat my fatigue. I had several stressful episodes in life which made me crash very bad. I megadosed on benfotiamine 1300mg, faced some paradoxical reaction but after 3 waves of fluctuating energy levels, my energy stablised.
Wow. That's good. Question. How much did you start off with? I am taking 300 MG daily of benfotiamine. Initially I felt great. Energy and digestion. But on day 4 I'm back to the fatigue in my legs again. Like a tired burning feeling like I'm always lifting weights. I camt recover right. I wonder if I need more benfotiamine like you are taking
the slide at 16:13 convinced me to try your methods. That's 4/6 the only exception is that, B-complex, magnesium and keto help me about 80%, as long as I'm very strict.
I have literally all of these symptoms except constipation (I suffer mainly from loose stools probably related to SIBO which I have been diagnosed). Just ordered TTFD and a B complex. Can't wait to feel human again. I remember taking Allimin Ex Plus in japan and feeling absolutely incredible and couldn't think for the life of me what happened. It's only when I connected the dots when someone said TTFD was developed in Japan that it finally dawned on me.
Hi, I also have sibo, sore throat, diarrhea and constipation, slow emptying of a stomach. This is the first week I am trying out thiamine hcl, small dose. I was wondering if you are seeing any results
I have all symptoms like Person 2. I TRIED EVERYTHING for almost 9 years...I tried two days ago to add TTD, my bowel movement is already better and today is first day after many years I feel warm!!! Im already about month on low oxalate diet and many symptoms improved. I found that candida, clostridia and stapth aureus can produce thiaminase enzyme that disable thyamine. I added probiotic with some components for killing candida. I still have leaky ears at night, hope this will help! Much love for Eliot and hopefully I will be able to contact you in the future for my main problem Polycistic kidney disease.
Same here. Accupressure is whats helped me. Ive been to the emergency room 4 times in the last 2 weeks and within 1 hour I went from being scared for my life to feeling better than I have ever felt. I feel warm again. I took 450 mgs of B1 an hour before I first tried the acupressure. Im in shock. I thought I was a dead me. Im not going to stop here though. Im in this for the long haul. Another thing to note, I am able to lay flat on my back without having heart palpitations for the first time in 20 years.
One of the best people to explain health connections .... is it okay to share your insightful easy to understand explainations I thank you from the bottom of my heart .. eczema less brain function up fatigue which was crippling now way way better calmer overall too .
100% this video is true, for years keto made me feel better then how terrible i felt eating carbs. But i truly felt better after starting thiamax or thiamine ttfd.
How do we get our doctors to treat us with nutritional aids and diet instruction mine even tells me that si of no help but I know better from treating myself
Elliot, do you do telehealth consults with Americans? I somehow missed your info about the crash until this video. I guess I'm trying to navigate my first post treatment crash. I'm hoping the rest of this video gives me an idea on how to get out of this crash.
Hi Elliot I saw your videos. Since about 1 month, I have reflux, which came like out of nowhere. I could not breath, enormous pain and I sweated like hell.just under the solar plexus. Since then, it comes quite often. To my person and background. I am 62 male and live in Thailand. I do running sbout 3 times a week and also intermediat running. I eat for breakfast mostly oat fruits with greek yoghurt or fat free yoghurt or brown rice with vegetable (mostly green) and chicken,egg, seafood sometimes avocado also fish. No smoking and almost no alcohol. I do/did like my 2 cups of coffee after breakfast . So I thought, I live a healthy life. So when I saw your videos, I thought I could cure my reflux with thiamine. I saw a doctor for that and he treated me for to much acid but I think he should have treated me for not having enough acid in my stomach. Thank you for your advice Regards Herbert
If you cannot digest red meat well or don't eat it, that's low stomach acid, and I would never be able to thrive on the diet you have! So "healthy" is not the same for everybody, be opened to change.
You are bang on with this Eliot. BUT this only works if the thyroid works properly. So the patient must be checked for issues and treated with iodine and selenium if necessary
Wow... I suffer from many of those symptoms so this explains a lot of my past 2yrs journey trying to figure my own health issues out... I have heard great things about carnivore and I know the vegan diet is not a eating plan I want to go back to on my life since I tired it for 6 months with worse results in my health outcome... Looking forward to the carnivore diet with supplementing on many vitamins and minerals... Looking for feed back from people on their health journeys on diets good or bad issues... Thnxs and be well friends
It's worth noting that two of the three cases in this video got worse on a carnivore or keto diet. One needs carbs, but needs thiamine to help process those carbs.
Carnivore is part of the solution, but cannot resolve the B1 deficiency on its own it seems. If the condition is severe, then trying to digest meats/fats would be near impossible I would imagine. But I do agree with carnivore as the foundation is nutrient & caloric dense very bio-available foods. It also eliminates oxalates and lectins that can possibly worsen the B1 deficiency condition. Introducing safe healthy plants later on would be your best bet once you're able to get past the hump of this horrible condition
@@JYAN2852 Nonsense. The more foods one eliminates, the worse the condition gets. And besides, thiamine is one of the nutrients needed to help process oxalate. And GLUCOSE of all things, helps restore not only glycogen, but the mucin barrier of the gut lining. Here's a case study where the anorexic patient's body temp didn't normalize until glucose was added to her thiamine... www.metabolismjournal.com/article/0026-0495(83)90063-X/fulltext
@@DDumbrille While I respect your opinion there is one fact that we don't seem to consider. There is no such thing as an essential carb macronutrient to make glucose. The liver makes as much as the body needs via gluconeogenesis. We don't need to be stuffing ourselves full of it. In doing so and stripping all of the micronutrients is what caused Thiamine defiency in the first place.
@@JYAN2852 Gluconeogenesis is a catabolic process due to insufficient carbs. I don't know about you, but I've already lost too much muscle to go that route. The only thing that's finally helping me turn that around, is increasing carb intake. But you make a critical point -- and I agree -- we don't need to be 'stuffing ourselves full of it'. That's so true. But we also don't need to be avoiding it like it's a poison.
Does that means benfotiamine works temporarily and provides symptomatic relief only in dry beriberi patients? Please answer because i am suffering from it and I can't tolerate carbohydrate little bit
If low thiamine can cause high pyruvate or high lactiate? What else helps body process with acetylcholine beside thiamine (reacted everytime tried to raise ACH)
Is TTFD same as Allthiamine? Can thiamine defic cause blood to coagulate or be thicker or maybe just effect the endothium health? Sounds like diet, life, stress... effect thiamine and guessing genetics. Thanks Be Well ! TY to all for commenting as helpful for many!
Elliot, could you elaborate on why it is that some people that are thiamine deficient respond poorly to B vitamin complexes in general? I've found that high doses of folate (over about 400 mcg L-Methyltetrahydrofolate) seem to consistently lead to a very anxious state of mind along with some nerve pain. For anyone who is curious, my case is incredibly similar to Case 3 in this video. Everything outlined there is almost exactly what I've experienced in the past when my issues were at their peak minus the excessive salivation.
your genes may have been used to get b complex from bacteria and you could have lost that bacteria from antibiotics or any traditional doctors treatment medication/theraphy/procedures
This is now one of my top favorite videos on TH-cam! You are a wealth of knowledge. My 78 year old mother has been dealing with beriberi (or NA-WE) from a lifetime of eating white rice. She slipped and fell on some ice over the winter and has not been the same since. She has all of the classic symptoms of B1 deficiency as you talked about. The B-complex isn't cutting it and never knew about TFFD. I will buy a bottle of it today and start her off on 100mg/day along with 400mg magnesium glycinate. Will she also need the other B-vitamins? If yes, which brand and doseage would you recommend for someone with moderate beriberi?
@@msroja2003 TTFD is a step above benfitiamine actually. I don't think Dr Berg is aware. TTFD is not only more effective but also pricier unfortunately. I recommend both to my clients depending on the situation. Both are great B1 options for temporary megadosing to overcome deficiencies
After being told countless times by multiple doctors that I was making my heart problems and dysautonomia symptoms up in my head and/or psyching myself out and bringing symptoms of POTS on(I wasn't even anxious and was told by 2 cardiologists that I was making myself anxious and causing tachycardia) I researched for about a decade never finding a cure for this nonsense. Traditional doctors can be absolutely blinkered and gormless. I found the whole experience bizarre. A grand total of 2 bleeding blood tests were ever done of all the doctors I visited the last decade. The tests were Iron and Thyroid function. Pathetic... I know people without health issues who have way more blood tests than I had, but my expensive doctors didn't issue anything intelligent to get to the bottom of my dysautonomia and fatigue. Bizarre. My uneducated high-school brain could have done better than that that the time... I took matters into my own hands for the next decade and eventually discovered that the dysautonomia I had been experiencing was most likely the cause of low vitamin b1. This dysautonomia was absolutely exhausting and caused me a major setback in life. Every aspect of my life was slipping away. No energy, extreme tachycardia, mood disturbance and general misery. This all from having been a very happy person up to the "crash" as you refer to it. Fast forward to 4 months ago. I finally start supplementing the ineffective HCL B1 form and already this helps. I then do more research and get hold of Sulbutiamine and this works nothing short of a miracle. Energy levels are coming back. Heart problems are waning significantly. Mental fog and mood disturbances are disappearing. I am starting to feel normal again. I never believed this possible... I have very little faith in doctors and quite frankly their work on me had been pathetic and it took me to fix the issue. A shame I wasn't told about b1 an entire decade ago by the expensive doctors and cardiologists I visited... Nothing... I am now ordering Thiamine in the form of Tetrahydrofurfuryl Disulfide or TTFD, as that's where my research has lead after soaking up your amazing work. I can't thank you enough Elliot. It's lucky that I found your videos. I am getting back my quality of life that I had all along before this deficiency. Looking forward to seeing a potential even further boost with TTFD. It's lucky that I have a scientific and research based mind, as I could imagine few other people have the patience and expertise to self-diagnose to the degree I did and it breaks my heart that such people are not getting the help that they need. We need more doctors who know the modern scientific literature and conduct the proper testing, but alas, science and pharmacology is always changing so doctors can often only be so knowledgeable. Still there is no excuse for gormless doctors. Perhaps the use of AI will help diagnosis in more fine resolution in the future where the measly brain of a doctor can't keep up! Pity some have to suffer for so long when the answer is there from the beginning. Thanks for your amazing work Elliot!
I have had a similar experience to yours and I’m thankful for my research-based brain and ability to think outside the box. Doctors just don’t get it. Thank you for sharing your experience.
What is the best form of supplementation? I heard somewhere that it has to be in powder form. Something to do with the chemicals used to put in pill form was an issue for some reason. Is this true? Should I buy a standard B complex in the Super market? Prices can range greatly. What's the difference between cheaper ones and more expensive ones? This is could be a video subject. I have noticed times where I feel unusually cold.
Can I supplement with Thiamine HCL, Magnesium Chloride and D3 for thiamine deficiency? I’m reacting negatively to everything, will the low thiamine dosage still heal me?
Love your Videos Elliot, I have had symptoms of Thiamine deficiency for 3 years. (66 yrs old) I watched your video on Oxalates with Sally and went on a low ox diet and felt really good immediately for 3 weeks then the dumping started. The Benfo causes dumping and I cannot take high doses and still function. I'll just try to increase as I get better.
I started taking Benfotiamine 300-600mg and then switched to TTFD 150mg about 2 weeks ago and my blood pressure is all over the place the sphygmomanometer won't even register numbers (shows error). I kind of feel better and worse at the same time, it's bizarre. Did you have troubles in the beginning too? How long did it take for you to feel better?
Beauty Psycho. Yes I had trouble in the beginning; it made me super hyper : heart racing, sweating, hyper alert. It scared the crap out of me. So I restarted and went up slower. Any change in dose takes four days before I feel it. Because of that I made lots of mistakes in the beginning. Benfotiamine gives me terrible pain. I don’t understand why. I think my deficiency was caused by decades of overeating carbs combined with a very high stress life. I’m eating carnivore since oktober and my stress is much lower also. I also have other deficiencies, I’m a right mess 😂. But I’m getting better because I understand the carb problem now.
@@violiendamast The funny thing is I felt a lot better on a Paleo diet than on Keto. And when I tried going carnivore recently, I almost felt like I need to go to ER! If higher carb diet increases the thiamine requirement, how come I feel so much worse without carbs?
I have just found your channel .... thank you so much for sharing the knowledge. I have had 3 times in my life (now 72 years) when my whole system collapsed. This last one has been the hardest for me and I am so grateful for finding this link to thiamine. Hopefully it will resolve the 2 autoimmune diseases I know I have and put me back on the road to recovery. 🙂 I have the rocks in my stomach sensation which makes turning over very difficult. Lemon water before going to bed helps. I think its a gas build up but it bruises the surrounding tissue.... very uncomfirtable.
Hello Elliot, thank You for sharing Your experience with Thiamine deficiencies. I wonder what one could do if the standard Thiamine supplements ( B1-HCl, Benfothiamine, TTFD) are not tolerated well ? I was trying to overcome chronic fatigue working with all of those supplements (about 2-3 months) after being strict carnivore for about 6 months but my stomach clearly says No to them. I get terribly irritated and nervous even on low doses ? What would You suggest ? Greetings from Germany *
Lots of possibilities. I see benfotiamine causing digestive issues in some people, whereas TTFD does not. On the other hand, many people don't tolerate TTFD. It could be that thiamine is not you issue. Alternatively, it could be a dysbiosis issue. Finally, irritation and nervousness are sometimes the ordinary signs of adaptation, and if cofactors are not taken in conjunction with the B1, it can cause these symptoms.
@@EONutrition Thank You for Your thoughts on the matter - my digestion is regular when I eat beaf and I do not have a past of gut issues. I took a B-Complex together with the TTFD and had similar issues when adding Mg-Citrate. My fatigue is mainly in the head and taking a Ziolith-Binder seems to improve my status. Maybe it´s rather an Oxalate issue... Appreciate Your advice, stay healthy ! *
Fairly new to Carnivore diet.. a couple months. I'm hooked on Coffee/Splenda/Half and Half, and got Nailed/Fooled by some Keto Snacks. Turned out to be Thiamine issue as you describe. If I have a "Bad" Keto Snack the night before (they come in 3's), the next morning, I have this Panic Attack thing.. I know something is wrong, sometimes BP goes up to 145/85, and I go into walk it out mode.. usually 10 times around the house. Worst case I have some Clonazapam (.25mg) which keeps from from calling the ambulance anyway. Seems to help if I eat the usual Eggs and bacon breakfast soon after I get up, and hold off coffee a bit. This morning I took a Vitamin B1 along with the usual Beet Root and Niacin. Wow.. took 45 minutes.. but it just went away!.. Looks like this could be the problem.. KETO SNACKs are for emergency use only.. I am pretty sensitive to any sugars/carbohydrates since carnivore. Carnivore diet kicked off the Coffee addiction which is being reduced.. Splenda is bubbling up to the top of the KICK IT list as well. A few Bumps in the road going Carnivore.. but clearly major improvements in every facit of my health Teeth, Hair, Skin, Mosquito Bites, Clarity, Motivation.. Wow..
Yes.. I'm taking Bentotimine(?) 600 mg.. form of B1.. works for me. Another symptom I had was while I was doing my house walking, I'd forget to breathe! I'd find myself almost gasping for breath! The Autonomic nervous system was Messed up.. What you say fit's my situation.
Greetings from USA. Than you thank you. You've described exactly what happened to me 20 years ago, after 23 years of vegetarianism. Wish I'd known you back then. All I got from doctors were tranquilizers. I had to figure it out myself. I just became aware of the Thiamine issue and am starting to take it since I still have some symptoms. Have heard that cocarboxylase chloride is the best form of it. What do you think?
Should one stop or minimize carbs when trying to fix Thamine deficiency? I'm doing Carnivore but I eat about 100g carbs at dinner for sleep and thyroid.
That's not Carnivore. Carnivore is basically meat and eggs seasoned with salt. Some people can tolerate a little dairy here and there. Broth. Healthy fats. Even with keto, the standard protocol is around 20 grams daily, usually from veggies. Oxalates and other chemicals from plants, can cause chronic health issues. This is one of the main reasons people choose to go Carnivore. To give their body a rest needed from plant consumption.
I've been drinking increasing amounts of sugary lattes the past few years and noticed I had declining health. I began to cut back because of the caffeine's effect on my sleep and energy levels, but noticed not the same improvement that I had the first time I consumed too much caffeine and reduced to a low intake. Then I got COVID, followed by some type of gastrointestinal infection, then RSV, and then some UTI/STI that I took antibiotics for. Kept getting worse after each event even though I kept improving my lifestyle and diet. Now I realize I was doing and having just about everything wrong (except alcohol abuse) for my thiamin levels, for years, and that COVID probably caused the crash.
I did the diet thing but didn`t get better. I just startet on Thiamine and now I am gaining weight. Also waiting for my order on benfothiamine 250 mg to arrive. Looking forward to it.
really interesting ive suffered from a lot of these symptoms and struggled with my weight I found extremely strict low carb to work well for me. I noticed a lot of the symptoms correlate with issues caused by thyroid , temperature regulation, weight management, chronic fatigue, libido problems etc are the two connected in someway?
Thank you Elliot you have saved my life. Omg I was living in mold and started drinking alot. Chest pains diareah etc...by a miricle I went to a demi lovato concert and started to heal based on I think the limbic system effect. Im very sick brain fog and gut disboisis mostly eat carnivore low fod maps foods and low oxalate foods. Low purine. No nightshades. Im doing better but how much of B1 should I take?
Hi, just discovered you and I think you are too smart for me. Question: is it ok to take high dose of thiamine without balancing out the other b vitamins? Or is that old science? Thank you 🙏
Mostly meat and fats have helped me tremendously with this but nothing like sulbutiamine!!! It’s the best thiamine you can get…day 1 of taking, I felt like a new woman.
Nuked my thiamine for years without understanding how this worked. Coffee, tea, polyphenols, high vitamin A foods, alcohol, sugar. All reducing absorption, using it up, or binding it to aldehydes built up from slow ALDH. Cutting vision A was a huge step to fixing a lot of things but knowledge of thiamine is another game changer.
I did the exact same thing the past few years. Ever since I was a teenager really, but much worse the past couple years. Excited to get my Thiamax and begin the dosing protocol and see if it helps.
@@TheSpecialJ11 I found it had a sort of antidote effect. Helped me for a little bit and it did seem to cure my apnea but not sure if it's doing a lot for me anymore.
I hade same as case 2. I have used tudca, omega 3 codliver oil, all 3sorts of thiamin, riboflavin, nicotin acid mostly lower dose. Magnesium citrate mostly, metyl b6, b9, b12 somedays higher dose, mct oil, kolin, vitamin a, c, d, k2, minerals tried alot. Kito somtimes carnivore helpt to survive for month before starting b1 therapi.
Can this be diagnosed through simple B1blood test? or is serum not reflective of tissue levels? Was on adderall for 6 years along with caffeine, and a high sugar/carb diet, poor nutrition... i had a organic acid test done as well which showed B12 deficiency [ adenyo/methyl] Can i look at markers via my OAT?
There are a few markers on the OAT - 2oxoglutaric acid, Pyruvate, Lactate, 2-hydroxyisovaleric acid. However, these are sometimes "normal". Bloods are unreliable
@@EONutrition ty that's why I'm going more by my OAT. I had normal B2 but low B12. Also low molybdenum per my HTMA. Which is a co factor for b12 absorption. Would all those factors you mentioned be low?
This, for me, is the ultimate answer to my chronically severe neurological, cardiovascular, cognitive issues and so much more ; all of which I very strongly assert are related to statins therapy. Two years keto reversed T2 diabetes and digestive issues but stopped working and same with two years carnivore. Developed heart issues and chronic fatigue left me in bed constantly. Couldn’t walk due to dizziness/disorientation/nystagmus. Scans revealed widespread demyelination in brain and spinal cord sheath. The palpitations, muscle twitches, extreme fatigue and weakness were overwhelming and I truly felt I was dying one cell at a time. The rollercoaster of psych symptoms no joke either. Went from loving life extrovert to fearful recluse. Oh and the pain…the pain in muscles, bones, ligaments and joints was unrelenting. Developed meat aversion but still craved fat and connective tissue !🤷🏽♀️
Most carbs caused pain and swelling in abdomen and joints and immediate crash needing to sleep . Breathlessness and severe sleep apnoea persisted. It just goes on. Anyway, found this amazing channel and tried 500mg B1 initially but no noticeable improvement. Added B complex and Amino acids complex. Started to feel almost human again but still chronically fatigued, postural dizziness, heart racing. Increased B1 to 500mg x 3 daily and wow! Balance problems gone in a couple of days. Cognitive decline improves daily. Added taurine, CQ10 and magnesium LLM1, d3MK7 and this stack after 30days approximately has been life restoring. I can’t thank EO enough for this priceless information and his willingness to share it. I dread to think what would be for me without his help THANK YOU 🙏🏽 ❤
So happy for your results!! What type/form of B1 do you take x 3 daily? Are you able to sleep if you take it later in the day?
@@bartginger123 B1 500mg (thiamine HCL), from Amazon UK. I have tried other forms and they don’t seem to provide me any added benefit and are more expensive. No sleep disturbances.
@@jennygibbons1258 Thank you so much for your reply. I was reading your experience again and it's really incredible! I have abdominal bloat and swelling from gluten & dairy (not sure about carbs in general). I get fatigue and insomnia, as well. Do you mind if I ask how much taurine and CoQ10 you take (and what time of the day)? I've never taken an amino acid complex and suspect I should research those, also. I am so glad you commented here a while back and shared your personal experience. So helpful! 🙏❤
@@bartginger123 I have to admit I struggle with consistency. However, I try to remember to take taurine twice daily, the second dose no later than 3pm coz I don’t want insomnia. I have had to trial and error to find my own baseline that is both effective and sustainable. I have also learned to be prepared to readjust because my body gets used to things and sometimes what worked for a while just stops working. I have learned to scale up or even down to see if it helps and this is why it’s so important to be your own advocate and do personal research. Hope this helps
@@jennygibbons1258 ❤
00:10 - Summary of examining what sort of symptoms someone experiencing thiamine deficiency. What are some of the causes of why people develop this deficit? And if carnivore or keto diets are sufficient for addressing this deficiency? As well as some case-studies regarding people on keto or carnivore diets that they didn’t see results on that diet until supplying thiamine at high doses.
01:01 - The many signs of thiamine deficiency are GERD [gastrointestinal esophageal reflux disease], bloating, constipation, delayed gastric emptying, gastroparesis, visceral hypersensitivity, undigested food in stools due to lack of pancreatic enzymes from low stomach acid, gut pain, dizziness, POTS [postural orthostatic tachycardia syndrome] & visual disturbances, low/unsteady blood pressure, tachycardia, central fatigue or systemic fatigue, fibromyalgia, chronic fatigue syndrome, carbohydrate/alcohol intolerance, neuropathy/pain tingling, poor temperature regulation, insomnia, low/high appetite, inability to gain weight, Raynaud's/poor circulation, EMF/light sensitivity, brain-fog/anxiety, breathlessness or air hunger, sleep apnea, etc.)
03:44 - The real pioneer of this therapy is Dr. Derrick Lonsdale, part in due to research done in Japan. He found benefits by pioneering research in the Cleveland Clinic to treat autonomic nervous system dysfunction, autism, ADHD, behavioral & neuropsychiatric disorders, chronic fatigue syndrome, post-viral fatigue syndrome, etc. All with Thiamine.
04:32 - What you really need to know is that the more glucose you need to process the more thiamine you will need. Because thiamine is absolutely critical for glucose metabolism and fatty acid metabolism. This is through glycolysis generating as a co-factor for the enzyme called pyruvate dehydrogenase. It is also a co-factor in a process called the Kreb cycle, which is the next stage in how we are deriving energy from various food components. Thiamine is necessary for glucose and fats, and proteins for energy as well.
05:15 - Some of the other main functions is that it’s a co-factor for many other enzymes such as for Anabolic Reactions such as the Pentose Phosphate Pathway used to regenerate glutathione to protect against oxidative stress, and also how we synthesizing macromolecules such as fatty acids to make myelin sheath (antioxidant system, nucleic acid synthesis, fatty acid synthesis). Furthermore, thiamine is central in how we are breaking down certain amino acids particularly from red meat sources or sources that contain leucine, valine, and isoleucine, so how we are breaking these down is relying upon a thiamine dependent enzyme, this falls under Branched Chain Amino Acids (energy metabolism, cholesterol synthesis, neurotransmitter synthesis). Likewise, how we are taking certain odd chain fats and running them through a separate phase of breakdown called Alpha Oxidation is a fairly new established function of Thiamine known as Odd Chain Fatty Acids ( Acetyl-CoA, etc. Energy Metabolism).
06:30 - Aside from its role in processing macro-nutrients, it's also central in the nervous system. In fact, a thiamine deficiency primarily affects the nervous system or affects the nervous system first of all. It is needed to synthesize the neurotransmitter acetylcholine and also glutamate and the inhibitory neurotransmitter GABA. Furthermore, neurons utilize thiamine in how well they are able to regulate the various ions across the plasma membrane. And then we are using it to maintain and build myelin sheath. And actually, one of the forms of thiamine is necessary or seems to be necessary for how we are conducting nerve signals transferring information from one neuron to another neuron.
07:21 - There are certain areas of the brain which are particularly sensitive to thiamine deficiency, and this is because they have a very high-rate of oxygen utilization and energy metabolism. And these are the lower portions of the brain referred to as the brain stem, mamillary body, cerebellum, hypothalamus, thalamus, etc. Interestingly these parts of the brain are primarily in control of the autonomic nervous system, which is divided up into two main branches. The sympathetic [fight or flight] and parasympathetic [rest & digest] nervous system. And what this is essentially doing is it allowing us to adapt to environmental changes or environmental stimuli via controlling those involuntary processes that we don’t need to think about [body temperature, digestion, heart-rate, constriction and dilation of our blood vessels, etc.] and when we are thiamine deficient, these areas of the brain and this area of our autonomic nervous system are most affected. And we can end up with dysfunction in this area of the brain which creates dysfunction in the entire nervous system, as we begin to fail to adapt to environments appropriately. Essentially losing anti-fragility in the process due to having all types of misfiring by being thiamine deficient.
08:52 - Lonsdale characterized high-calorie malnutrition. This comes down to an up-regulation of macronutrients (refined fats, refined carbs, reined proteins) and down-regulation of micronutrients (vitamins, minerals, other nutrients). And as we consume too many refined macronutrients we deplete ourselves of micronutrients which leads to many of these disorders listed above. This excessive intake of glucose without adequate levels of co-factors that thiamine and other vitamins and minerals provide lead to sub-clinical deficits that leads to all sorts of a constellation of symptoms as illustrated throughout this video. Thiamine is particularly necessary for the appropriate metabolism of carbohydrates in particular, so those diets higher in carbs especially refined ones as you see with Dr. Ray Peat will require the higher need for thiamine and its cofactors, B-complex, magnesium, and potassium.
11:06 - Based on this concept previously spoken about here. The autonomic nervous system is in control of things like blood pressure, gut motility, body temperature, constriction and dilation of blood vessels, and those parts of the brain are also in control of appetite, and nutrient partitioning. As we can see many of the symptoms can be linked back to problems with the autonomic nervous system which is linked to thiamine deficits.
11:42 - Some primary risks are heavy alcohol use, whether binge or chronic use. High sugar consumption, white rice, refined carbs (bread, grains, etc.). Chronic digestive issues IBS-C or D, or A, diarrhea, constipation, etc. High activity stressors: athletics, workload, family breakup, or trauma. They tend to be Doers, so go-get-'em attitudes tend to lead to a crash due to thiamine depletion, this is partly due to ramping up the metabolism which requires a greater need for micronutrients like thiamine and its co-factors. Pharmaceutical Rx like diuretics or antibiotics (metronidazole) also induce deficits in thiamine which cause thiamine-wasting. Surgery/viral or bacterial infections low-grade or otherwise.
14:30 - After crashing from one of the above, generally you will see further carbohydrate metabolism and alcohol metabolism intolerances. Nervous system collapse, on fire, or chronic fatigue. A negative response to B vitamins & sometimes magnesium. Slight improvement on keto/carnivore diets but about 50% or so, this is because there is less requirement for thiamine on these diets. However, this doesn’t mean to stay on these diets as it doesn’t address the deficit but buys time. Neurological cardiovascular and/or digestive symptoms. Insomnia or not feeling rested after sleep. These all can drastically impact overall well-being and make it difficult to discover how to recover from this deep thiamine deficit.
17:10 - It is important to note that in opposition to the conventional way of viewing disease. Elliot Overton likes to look at it as a Spectrum of Severity. A conventional medical physician sees it as falling in the box of health or disease. But there is a large grey area in-between. Someone could be moderately healthy, but still, have moderate insufficiency, and they could develop a deficit of thiamine or other micronutrients as they gradually develop this deficit. But because they do not fit the diagnostic of a full-blown disease medicine dismisses them because they don’t fit diagnostic criteria. Which makes people ignore subtle sub-clinical deficits for long periods of time which can wreak havoc or lead to the straw the breaks the camel's back as it were.
18:15 - The Crash or Trigger is usually the straw that broke the Camel’s back. Metabolic stressors (trigger) are often from a chronic insufficiency minor or few symptoms and on the timeline, a Crash & Metabolic Shift can occur with multiple symptoms manifesting due to enzymatic down-regulation. It could be a loss of a loved one, car accident, surgery, excess food shifts, loss of a job, etc. So this acute event usually sends someone over the edge which shifts someone’s metabolism as they begin to develop symptoms they never had before, which seemingly randomly comes out of nowhere. And in the literature, it shows that actually people who are deficient in certain nutrients like thiamine, then the enzymes that use this nutrient you’ll see down-regulated which creates this enzymatic down-regulation which has to do with a sudden onset of symptoms out of nowhere that relied upon those enzymatic processes.
19:46 - So if we look at the full-blown deficiency of thiamine you find Berberi & Wernicke’s Encephalopathy. Which usually requires 100-1,000mg of thiamine per day independent of a healthy diet. Therapy may be necessary for 6-12 months to achieve full-blown remission of this disease. And carnivore and keto diets may simply reduce symptoms but ultimately you want to restore carbohydrate metabolism. And this is more evidence that diet alone is simply not enough. The RDA for thiamine is currently only about 1-1.5mg a day.
21:33 - Case Study 1. Male mid-twenties with a Medical history of {Neuropathy, Severe Constipation (once every 2-3 weeks), GERD & constant bloating, Severely underweight 116 pounds [53kg] at 6 feet tall and inability to gain weight, Unexplained low blood pressure, Autoimmune issues, Extreme fatigue, dizziness, breathlessness, and low blood pressure}. This client has had a very high and long consumption of white rice as a staple in his diet. And he has his Trigger being hospitalized 10 years prior. He tried multiple diets, even a strict PKD Carnivore diet for around 6 months, which helped with autoimmunity but not most of the other symptoms. He saw Elliot’s videos and got in contact with him. As he looked at it, he had this individual take TTFD (bioavailable thiamine titrating up to 150mg a day), high dose B complex, vitamin C, and magnesium malate.
24:28 - After an 8-week follow-up after one day, daily bowel movements. GERD, bloating, and indigestion almost disappeared after a few weeks. Gained 17.63 pounds (8kg) for the first time in nearly 10 years. Enjoys working out and is building muscle rapidly. Fatigue improved greatly, with no daytime sleeplessness. Overall immune symptomatic improvement in a short time frame. This all changed with just the suggestions of TTFD Thiamine with the co-factors listed above. Just another example of how some simple changes can drastically alter someone’s life.
25:39 - Case Study 2 Male mid-twenties with a Medical History of {Severe fatigue, and mental sluggishness, depression (feeling dissociated from the body), Chronically cold, and poor circulation, Chronic burping, and bloating, poor gastric motility (explaining that it felt like a rock was in his stomach) & constipation/loose stools, Terrible recovery from exercise, Previous neuropathy, palpitations (cardio abnormalities) and twitching.
27:07 - History continued: Long consumption of white rice/bodybuilder diet & alcohol during university. Antibiotics & infection trigger. Lost tolerance to carbs, coffee, and alcohol. Multiple variations of keto/carnivore for 18 months with some improvement, but still struggling.
27:54 - Lab work CBC + CMP Unremarkable. Organic acids (after a few weeks of B1 therapy). A slight elevation in lactate (related to low thiamine), 2-hydroxyisovaleric acid (BCKDH marker) [marker related to branch-chain amino acid metabolism]. Minor elevations in oxalate markers.
28:27 - Glycolytic Cycle Metabolites Lactic acid 22 High (acceptable reference range 0.74-19.0). Amino Acid Metabolites 2-hydroxyisovaleric acid 3.1 (acceptable reference range 0.41 or lower). Oxalate Metabolites Glycolic Acid 111 High (acceptable reference range 18-81).
28:42 - Therapy Worked up to 500mg TTFD Thiamine w/ Magnesium malate (he got worse initially, then got better, as this fluctuates due to increasing metabolic machinery to adapt to thiamine levels rising so titrate gently). With every subsequent increase in the dose, his symptoms got worse initially then better. Body heat increased like a furnace. Periods of feeling euphoric, better concentration, and energy. Bloating, burping, and digestive system made major improvements. Sometimes it can take 6-8 months to recover the machinery necessary to restore health from chronic thiamine deficiency.
30:02 - Case Study 3 Male early-twenties with a Medical History: Trigger - early stress at 10 years old, and he binged eat sugar as a coping mechanism leading to a bout of severe constipation. Gradually he developed the following symptoms. Burning mouth, feet, neuropathy. Severe SIBO, GERD, bloating, and slow motility + laryngopharyngeal reflux. Severe fatigue, poor temperature regulation, and no libido. Excessive salivation in the mouth, dizziness, and balance problems. Chronic pain, visual disturbances, etc.
32:00 - History continued. Tried almost every diet. Got worse with carnivore/keto & restrictive diets. Learned of thiamine deficiency, took benfotiamine before the consultation. Benfotiamine improved dizziness, and balance almost immediately. Saw Elliot’s videos and got in contact. Elliot doesn’t generally use benfotiamine versions, but the client noticed a difference with it at just one capsule a day.
32:44 - Therapy: Increase benfotiamine to 250mg 4 times a day. B complex, riboflavin & magnesium, etc. A gradual shift from benfotiamine to TTFD version of thiamine.
33:33 - Results after a few weeks. An increase in benfotiamine caused temporary improvement then worsening in symptoms. Shift to TTFD 300mg a day. Now able to say many different foods - meats, veggies, etc. within about two weeks on TTFD version of thiamine. Also able to exercise. Reflux completely disappeared, bloating/burping 70% improvement. Upper GI motility restored - bowel movement twice per day. Libido returned. Fatigue, LPR, and salivation still present. Early days. [My added suspicion might be sulfur metabolism issues with the benfotiamine version?].
34:21 - Case Study 4. Female mid-60’s with a Medical History: Air hunger and breathlessness with fatigue. Unexplained low blood pressure and high pulse rate. Central sleep apnea, and dizziness. History of metformin use (thiamine depletion). Elliot speaks to this case to illustrate how one single deficiency can manifest as several different symptoms.
35:53 - Therapy before coming to see Elliot: Self-prescribed 900mg benfotiamine and 600mg sulbutiamine, B complex and minerals, carnivore diet. She noticed little change in fatigue but a big improvement with air hunger and breathlessness. And her pulse rate balanced and her blood pressure balanced fast. When she doesn’t take that dose these symptoms return.
36:53 - Central sleep apnea is another one of those unknown symptoms of a thiamine deficit, related to oxygen deficiency in the brain.
37:04 - Thiamine Deficiency Disease, Dysautonomia, and High-Calorie Malnutrition by Derrick Lonsdale and Chandler Marrs. How to address this issue in more depth get this book!
37:48 - Next videos Clinical laboratory indications of thiamine deficiency. Are there lab tests available? Which labs might indicate a deficiency? Which is the best form of thiamine to take? What is the difference between the forms of thiamine? Which health conditions might benefit from which form?
Hello Dr. Brandon I have a question how do we test the thiamine deficiency ? I am a crossfiter and later I do suffer from chronic fatigue....I appreciate the video I think you nailed my problem.
I also have shoulder constant shoulder pain I think from uric acid or lactic acids , accumulation and my body can't fully recover after excersise
Very sincere thanks for all the time and effort you have put into this.
It makes a huge difference.
Thank You !
Brandon, your time stamps are super helpful and much appreciated. If there is a way to follow you, I will do my best to find it. Thank you for your time and effort.
I'm 54 and have had these problems for 20 years and now getting to the stage where I don't really leave the house. Depression chronic fatigue and sleep apnea are pushing my hope out the window. I have ordered your B1 thiamax and praying to God if there is one they work for me. Thank you for your video's
I'm pretty happy with Benfotiamine. I take around 450MG (16th of a teaspoon) 2 to 3 times a day. It has literally changed my life. It took 4 months at first because I was taking too small of a dose.
Hang in there and give it some time.
I also had food sensitivities. Had to give up high nickel foods and all milk products 😭, but that cleared up my flu like pain.
You may also want to try Now 1000 mg NAC with Now glycine. The powered is cheaper than the pills. I have a goal of 100mg per kilogram to reverse aging. Look up GlyNAC.
Try going to a clinic and getting a vitamin B shot. It gets absorbed more quickly by the body. Do a Google search, and search for vitamin IV near you.
Remember that Elliot recommends several cofactors, including vitamin b2, b5, b6 (in nicotinamide form), magnesium (in whatever form you can tolerate best), coenzyme q10, and a few others depending on your issues.
@@NateB may you provide examples of other cofactors?
Elliot! I’m so glad to have discovered you! I was struggling with vertigo/dizziness/balance issues for some months since August. Went to a neurologist and an ENT. (I’m 77, have hearing loss, wear aids since childhood) and suffered vertigo once in a while through the years, especially after stressful situations. The neurologist ordered an MRI which I had done Dec 1. Still not told outcome of that. At any rate, after learning about Thiamax, I thought I would give it a try. I take one every day. Right away I noticed the weirdness of my off-balance “dizziness” was gone. No problems since! Thank you, thank you.
Awesome
It's a miracle this video randomly popped in my newsfeed & my landed right at the top comment, which is yours. I had two acute bouts of vertigo last year that were terrifying. The first one hit me in May and after that the brain fog, balance issues & mild nausea have never left.
Going to try thiamine now.
🙏
@@peynattyl How is the thiamine supplementation going?
@@richardk5246 Brain fog and head pressure are much better, but not gone. I'm also taking an antihistamine every day and will for a month. The improvements are welcome, but I'm not yet cured.
@@peynattyl maybe you need more? Improvement is great!
Excellent video. Thanks a lot for this. I supplemented B1 after being on keto/carnivore for 8 years and felt like i have a new mind/body. Most particularly, my digestive symptoms, irritability, and fatigue have improved remarkably.
Good to heard that. What brand of Thiamine are you buying? Could you share it with me?
Hey what kind of thiamin you use?
I know this is an old comment, but if you see this, I’d sure appreciate you share your dosage and type of Thiamine!
@@Angie_9942 true. Me as well.
what were your digestive issues?
Air hunger is something I never have had a word for, and nobody I explain it to understands. It feels like you're dying when it's really bad.
I've had it when I was very ill
I understand that entirely. Is it worse for you depending on the weather? I can't handle very hot weather. Couldn't breathe outside yesterday. I ended up fainting, decided to go inside and sleep.
I developed air hunger consuming for 1,5 year to much alcohol!
It is terrifying!
Alcohol depletes vitamins and so on. So b vitamins too among others.
No oxygen enough in your cells ( mytochondria ).
@heide-raquelfuss5580 I've been there, it's terrible, thank God I quit.
@@jasonwilcox6637
I hope you found a way to rebuild yourself and got rid of air hunger and so on.
We have only 1 body!!!
I've spent 2 days down a rabbit hole listening to you, looking up taurine, thiamine benefits.Currently stacking B1 800mg (working up to 2000mg), B12 4800mcg, MCT powder. I'm so chilled😏 I'll add taurine. You Rock!!!
I have had fatigue, dyspnea, panic attacks, chronic constipation, bloating, food sensitivities, anxiety, and general inability to deal with stress for over 4 years now. I tried many things and nothing worked. It was causing me more stress and I was in this vicious cycle non-stop. What you say makes total sense. I have started low dose thiamin with magnesium and I'm already seeing positive results. I will move on to high dose thiamin and actively try to eat thiamin rich foods. I can't thank you enough for putting this information out there.
Those are what I have just ordered. Is it still working for you?
Hey there, I've struggled with loose stools, gas, fatigue, carb intolerance, and inability to recover from exercise for roughly two years. Symptoms developed when I was doing a lot of exercise (3-6 mile runs every day with weight lifting every other day) and then had covid followed by a course of antibiotics for an infection. For the last 6 months I had to refrain from exercise completely because I could not recover at all.
I recently started an animal based diet along along with magnesium supplementation (400-600 mg of malate and glycinate a day) two months ago. I did have an improvement in symptoms but improvement plateaued. 4 days ago I started TTFD and I've already had some huge improvements in fatigue and carb intolerance and a decrease in gas. My energy is improving daily and I think I might even be able to return to exercise soon. I am feeling more like myself than I have in the two years since this began. I am now suspecting I actually had developed gastrointestinal beri beri.
However, I have so far had not much improvement on the loose stools. In your experience, how long does it take to resolve GI issues once started on TTFD with cofactors? Thank you so much for your videos they have been incredibly helpful and offered a lot of hope to me in recovering from this.
Hello, I think I may have over-exercised my way into a deficiency as well. Since the start of covid, I have been getting at least 15000 steps a day as well as lifting weights 4-5 times a week. On top of that, I have also been intermittent fasting for about 16-20 hours a day. I recently started at a does of benfotiamine, 300 mg per day, did you start TTFD immediately or did you have any other forms of B1 prior?
You have to supplement potassium as well. Otherwise, you will damage your body
Got 95 % of those symptoms. No doctor ever head a clue and been suffering for decades. Thanks for researching in this field so ambitiously. Started to change my diet towards seeds, nuts, legumes etc. and taking Thiamine HCl in a moderate dose. Also avoiding caffeine, sugar and alcohol.
Did it help
@EONutrition Your work truly is fantastic. This is GOLD. I'll keep making notes as time permits. Hope you enjoy the time stamps. I am sharing your work on all types of forums so hopefully, you'll get some additional clients from all this.
Elliot, I wanted to share personal experiences mentioned in Case 3, the burning throat, and for me mouth and tongue. We we're inhaling methanol in Pulp Mill Emmissions building an Air Emissions Project beside a operating Pulp Mill. My last 3 days my body was like a piece of lead (hypoxia). There were 59 tradesmen on oxygen at the Hospital the 3rd day, and that evening I had the burning throat issues. I avoided Pulp Mills for a year and then got gassed again at another site! Vehicle exhaust started on-setting the same sequelae of symptoms as the year before, cardiac issues and the burning throat... learning there is formaldehyde in vehicle exhaust which metabolizes to Formic acid in the Liver then Lactic acid cellularly driving FM pain! It is the elevated Formic acid which causes the burning throat. There are also elevated levels of Aldehyde in E85 ethanol entrained Gasolines, being the hangover component of legal drinking alcohol, thus can lead to Thiamine deficiency for daily commuters. Assuming this young man also jogged on busy streets, he may have been inhaling Aldehyde. Then there is the soda drinks with an artificial sweetener derived from formaldehyde. There are Environmental complexities that affect our health. We we're also inhaling Aldehyde and Potassium, but that can be shared later.
Case studies are so helpful. This is incredible. I’ve had increased sensitivity to coffee, going to remove from diet and supplement bentofiamin for a while.
This video explains alot of what I have went through most my life, thank you sit.
I'm a poster child for the Risks or Triggers and the After Crash pages. This happened when I was 8 and I've been struggling since. Up and down and finally into disability. Intolerant to alcohol, low HR, low BP, etcetera, inability to process carbohydrates (put on weight looking at food - yet, at my sickest I went from putting on weight to dropping weigh precipitously only to put it on again with the next big crash), no stamina and eventually a ME/CFS diagnosis. Couldn't handle folate (e.g, magnesium eventually helped me do that). Partial improvement on a keto like diet years ago only to go down hill again. Diet alone doesn't do it. I've been eating a fabulous diet most of my adult life because I'm not well and I'm sensitive to so many additives that I eat whole foods and it's rare that I consume a processed food. Also, I just crashed more after the Covid Vax, and reactions to vaccinations seem to put stress on thiamine for some. (BTW, for whatever reason, I don't deal with tachycardia any more, but that might be that I'm getting enough thiamine to knock that out.)
I think my health crashed at 8 because I'd stopped eating breakfast and lunch at age 6 (had a parent who wasn't paying attention and I got the message that I wasn't deserving of care) and then in year 7 had a lot of challenges to my health, including two severe infections, one emergency room grade fever, and surgery. My health turned a corner for the worse. Then, in my teens, doctors prescribed antibiotics for acne. I was on them for 5 years. Goodbye any chance at health.
Holy crud... nutritionist just recommended benfotiamine. I have every symptom. Mind blown. Starting tomorrow... hope I can start eating again and gain weight. Worst symptoms are aversion to food/ even water and psychosis. Carnivore diet has helped immensely but this is the missing piece. Thank you for the information.
How do you feel now?
Crazy year... so much better. I was very, very ill. I believe high dose thiamin caused some damage, however, as it induced magnesium deficiency. I was definitely deficient, but balance is key in healing. Grateful for the journey
@@anyagourleyglad you got better, were you taking too much b1 without magnesium? Also how are you now? Another year later
i am there as well
@@anyagourleyso taking it with the magnesium helped you get better
One of the best videos I have ever seen.
Great video, a lot of these symptoms dovetail with mine. Especially the crash thing. I also have mthfr, I am not sure on how that effects supplementing b1. But I did read in some of your comments that it can have extreme effects on anxiety. Some of the anxiety, panic attacks, while having a migraine and heart palpitations are things I’m looking to a avoid experiencing again, at all costs. I have been dealing with autoimmune problems (psoriasis) that have stemmed from a tooth infection I didn’t know I had. I can’t afford the surgery and it’s been hard to work with all these symptoms on top of the extreme life challenges that have come my way in the past few years.
You are my role model Elliot, thanks for spreading the light
Thiamine deficiency is what made civilization. Grains deplete it, changing the gut flora to make more nervous and hyperfocused (mildly autistic) humans who are afraid to stand out. Conformity. Specialization in the division of labor.
Dust Puss dude, that is profound.
Yah. That got me thinking... lol. Deep and profound. Hee hee hee snicker. But yah maybe ... what do I know.
I'm autistic and most autistic people I know have no difficulty with conforming. We, more often than not, don't conform or value conformity. I don't see a lot of people being hyper-focused out in the world.
I'm an actual autistic person and this doesn't stack.
True dat , I was praying for an autistic child & B1 was told to me what they need
THIS! This is worth keeping and listening to repeatedly! Thank you!❤
This is exactly what's happening to me. Concussion, father's suicide and loss of relationship all within a three month period, I feel like my entire system is constantly inflamed.
I’m so sorry for what happened, Winston. I hope you can find some recovery.
Great content!, From informational standpoint I'm curious, if therapy to resolve a defficiency does need lifelong supplemental support or can therapy be stopped when the symptoms resolve?
I assume it depends on why each person got too low. If it is still an issue I would think you always need help. If you are getting enough nutrients and know you can absorb them, you can just focus on nutrition. Not sure
20 + years insulin resistance at a lower weight to most diabetics...Many incidences of antibiotics due to undiagnosed hidrodenitis suppurativa inflamation.. many years of 5+ coffees a day, Drink way too much sugary wine when im not sticking to low carb.. alcohol tends to go right through me though. makes me shit water for a day. Active physical job and generally fit for a 40 something year old. . Improved many other things greatly on keto and zero carb diets over the last 3 years.. lost weight levelled bgl, stopped asthma depression etc... still suffering from occasional feet pain and swelling and hand and arm numbness and palps. CAnt lose weight aymore no matter what i do. Always assumed B vit deficiencies were a vegan thing. Starting to feel like I'm text book thiamine def the more i watch your vids.
oh also often get bad metallic tastes in my mouth could this be related?
I actually developed hypokalemic periodic paralysis without the genetic variants due to thiamine deficiency. Also hyperadrenergic POTS. The POTS started with me passing out behind the wheel of the car. I had already been Dxed with non-celiac gluten sensitivity a few yrs before with the undigested food diarrhea but I was still on a low carb diet. Had a very high viral load, do too. Never drank alcohol. It’s scary how far down the road towards death you can get if the problem is a primary nutritional deficit. No one really figured this out-YOU saved me Eliot. Once an emergency MD ruled out one thing and checked my Mg level, I extrapolated that thiamine and zinc deficiencies would follow. That’s when I found your channel. I actually do have an acute hepatic porphyria and Ehlers-Danlos type 4, but the deficiencies were so severe that the symptoms confused everybody. My thyroid is still screwed up, and other things too-pancreatic insufficiency (fat malabsorption), bone fragility, mold exposure...it never ends.
Sorry to hear that! It sounds like you have been through the wars.
@@EONutritionwhy is it you think some just some with some of these nervous system disorders heal completely with brain retraining? Just curious your take on this?
How are you feeling now? Hope much better
Continuing to binge watch your videos and others related to Thiamine deficiency - have tried just about everything else.
Not sure how or why your vids finally started appearing in my feed, but I have been on Optimal Ketogenic Living, Root Cause Protocol, Vegan, Vegetarian, Hallelujah Diets, Weight Watchers, etc.
I think the only video I got a clue on was when Mary Ruddick was being interviewed by a Carnivore doc - fell in love with her.....she has the brightest affect of just about anybody I've seen lately....she mentioned that the Carnivore Way of Eating might be deficient in Thiamine....so.....
The recommended book by Lonsdale and Mars is way too pricey for me, even on Thrift Books....a matter for prayer.
I did order what I thought was Allithiamine from Amazon, but the label I got was All Thiamine - it says it TTFD.
So, have ordered some Thiamox.....hope it's the real deal.
Also using a B-Complex from Desert Harvest without B6, since my hand neuropathy got so much worse after trying to treat "Pyroluria"....
Thanks for all your work, and putting the info online.....I and my family-of-origin/family-of-orientation pretty much textbook cases of Thiamine Deficiency......
CFS carnivore here. Took first does this afternoon, feeling much better. Brain fog gone, and much more mental energy. Horrible day turned better.
Took B active multi, which has 100mg HCI, and separately Allithiamine 100mg.
Still working? Heard you need magnesium as well
@@juanitahyde1265 no, took thiamine for a few months, it didn't help overall.
Diet is the only thing that helps me with my CFS.
I started high dosing ( started w 500 mg thiamin hcl BID) and had to quit strict carnivore ( went to carnivoreish, added a serving of fruit each day) because it induced oxalate dumping and tanked my potassium levels. I also upped my potassium, and other electrolytes, and reduced to one B1 serving per day to reduce the oxalate dumping ( and added vit c to reduce oxalate dumping, among other needs) and found some relief. Carnivore alone still left me w POTS and CFS.
You need to go to a clinic and get vitamin B shots. I've been on carnivore diet for a couple of years. Been pretty strict except for protein shakes I take twice a day. I also supplement with B vitamins, NAC, zinc carnosine, and pink bark extract.
How long were you carnivore before starting the thiamine? You started with a large dose it seems. I’m going to start tomorrow with a lower dose hopefully it’ll be easier. I’ve been carnivore 9 months.
@@beingbenign2685 90 days
This is me. For years. Pretty much since a young teenager & i’m now in my 60’s. Fatigued. Always tired. No motivation. Lethargic. Can’t tolerate alcohol. Never have restful sleep (when I can sleep). Struggle to lose weight other than VERY low calorie. Digestive issues for years culminating in almost total collapse. Can no longer digest/process animal protein. Did Keto/carnivore for over 8 years but only ever gained weight & it did nothing for my fatigue. Very slow digestion. Diabetic & cannot seem to reverse it regardless of what I try. Parasites I cannot overcome (they contribute to the nervous system stress - my nerves are so sensitive I can feel them constantly, more so at night, which contributes to the insomnia - I want to sleep but they give me no peace). I used to have GERD & a hiatus hernia, years of IBS, palpitations, neuropathy & high blood pressure, but dumping wheat, most sugar & pasteurised dairy managed to calm that down. my body feels very acidic (Lactic Acid). Osteoporosis. Periodontal disease I cannot seem to reverse (the acidity pulling alkaline minerals out of my bones, teeth & gums?). Chronic hair loss. Vision loss. Oh & did I say? Tired. All. The. Time.......
go to FB page Trying low oxalate diet (TLO)
I’m very sorry you have had these issues. I hope you are doing better now. I’ll be praying for you. 🙏💕
Omg 😳
Try intermittent fasting. And take vitamins and minerals daily, it's very important. Taking vanadium and chromium are vital for reversing diabetes. AND stop eating process foods, if it comes in a box and says natural it's not real food (bad for diabetes! ) you should be able TO SEE natural food 😉
Totally me
This video is a game changer. I have a ton of these symptoms. You have singlehandedly given me HOPE! My concern is this: you said that when people stop taking thiamine... the symptoms return...! What is the root cause here?? Any suggestions? I just bought some thiamine but will order yours from Amazon this week. Thank you for what you do. Truly! 🙏
I’ve watched quite a few videos and heard that at some point many people just take a maintenance dose.
Thank you elliot, you advice has really helped me combat my fatigue. I had several stressful episodes in life which made me crash very bad. I megadosed on benfotiamine 1300mg, faced some paradoxical reaction but after 3 waves of fluctuating energy levels, my energy stablised.
Wow. That's good. Question. How much did you start off with? I am taking 300 MG daily of benfotiamine. Initially I felt great. Energy and digestion. But on day 4 I'm back to the fatigue in my legs again. Like a tired burning feeling like I'm always lifting weights. I camt recover right. I wonder if I need more benfotiamine like you are taking
Another amazing video Elliot!
the slide at 16:13 convinced me to try your methods. That's 4/6 the only exception is that, B-complex, magnesium and keto help me about 80%, as long as I'm very strict.
You are helping a lot of people sir.
I have literally all of these symptoms except constipation (I suffer mainly from loose stools probably related to SIBO which I have been diagnosed). Just ordered TTFD and a B complex. Can't wait to feel human again. I remember taking Allimin Ex Plus in japan and feeling absolutely incredible and couldn't think for the life of me what happened. It's only when I connected the dots when someone said TTFD was developed in Japan that it finally dawned on me.
Hi, I also have sibo, sore throat, diarrhea and constipation, slow emptying of a stomach. This is the first week I am trying out thiamine hcl, small dose. I was wondering if you are seeing any results
I have all symptoms like Person 2. I TRIED EVERYTHING for almost 9 years...I tried two days ago to add TTD, my bowel movement is already better and today is first day after many years I feel warm!!! Im already about month on low oxalate diet and many symptoms improved. I found that candida, clostridia and stapth aureus can produce thiaminase enzyme that disable thyamine. I added probiotic with some components for killing candida. I still have leaky ears at night, hope this will help! Much love for Eliot and hopefully I will be able to contact you in the future for my main problem Polycistic kidney disease.
Awesome! Thanks for sharing and good luck in your healing journey
Do you mind sharing which brand you are using?
Same here. Accupressure is whats helped me. Ive been to the emergency room 4 times in the last 2 weeks and within 1 hour I went from being scared for my life to feeling better than I have ever felt. I feel warm again. I took 450 mgs of B1 an hour before I first tried the acupressure. Im in shock. I thought I was a dead me. Im not going to stop here though. Im in this for the long haul.
Another thing to note, I am able to lay flat on my back without having heart palpitations for the first time in 20 years.
did u have cold hands and feet? are u using the B1 on Elliot's site?
@@Noah-il2wf May I ask which supplement brand you bought or take?
hey man, great information, I appreciate your work! consider getting a lapel or other mic to improve your audio quality!
One of the best people to explain health connections .... is it okay to share your insightful easy to understand explainations I thank you from the bottom of my heart .. eczema less brain function up fatigue which was crippling now way way better calmer overall too .
Hope we get the follow up video of this soon. I've been eagerly waiting for it!
How about intermittent fasting strategies? Is IF (along with low carb/high fat diet) an effective way to to improve/normalize thiamine status?
This is pure gold.
Great video Elliot - thank you. I love the case study examples towards the end too. I look forward to seeing your next video.
100% this video is true, for years keto made me feel better then how terrible i felt eating carbs. But i truly felt better after starting thiamax or thiamine ttfd.
Great job young man!!!
I do appreciate these case studies, thank you for the valuable information.
How do we get our doctors to treat us with nutritional aids and diet instruction mine even tells me that si of no help but I know better from treating myself
Hi there.
I'm currently taking Thiamine HCL but looking to switch to TTFD.
Is there some way to compared equivalent amounts between the two kinds?
Great information! What do you think of nutritional yeast as a food source for Thiamine?
Its OK, but will not be sufficient for people who have serious deficits
@@EONutrition Thanks
Elliot, do you do telehealth consults with Americans? I somehow missed your info about the crash until this video. I guess I'm trying to navigate my first post treatment crash. I'm hoping the rest of this video gives me an idea on how to get out of this crash.
Hi Elliot
I saw your videos.
Since about 1 month, I have reflux, which came like out of nowhere. I could not breath, enormous pain and I sweated like hell.just under the solar plexus. Since then, it comes quite often.
To my person and background.
I am 62 male and live in Thailand. I do running sbout 3 times a week and also intermediat running. I eat for breakfast mostly oat fruits with greek yoghurt or fat free yoghurt or brown rice with vegetable (mostly green) and chicken,egg, seafood sometimes avocado also fish. No smoking and almost no alcohol. I do/did like my 2 cups of coffee after breakfast . So I thought, I live a healthy life.
So when I saw your videos, I thought I could cure my reflux with thiamine. I saw a doctor for that and he treated me for to much acid but I think he should have treated me for not having enough acid in my stomach.
Thank you for your advice
Regards
Herbert
If you cannot digest red meat well or don't eat it, that's low stomach acid, and I would never be able to thrive on the diet you have! So "healthy" is not the same for everybody, be opened to change.
Did it improve?
I’m always worried about toxicity. Who would I see that could recommend a total overall nutritional supplements that prevents toxicity.?
B1 like other B vitamins is water soluble and wash out of your system. So there is little chance of over dosing yourself
You are bang on with this Eliot. BUT this only works if the thyroid works properly. So the patient must be checked for issues and treated with iodine and selenium if necessary
Wow... I suffer from many of those symptoms so this explains a lot of my past 2yrs journey trying to figure my own health issues out... I have heard great things about carnivore and I know the vegan diet is not a eating plan I want to go back to on my life since I tired it for 6 months with worse results in my health outcome... Looking forward to the carnivore diet with supplementing on many vitamins and minerals... Looking for feed back from people on their health journeys on diets good or bad issues... Thnxs and be well friends
It's worth noting that two of the three cases in this video got worse on a carnivore or keto diet. One needs carbs, but needs thiamine to help process those carbs.
Carnivore is part of the solution, but cannot resolve the B1 deficiency on its own it seems. If the condition is severe, then trying to digest meats/fats would be near impossible I would imagine. But I do agree with carnivore as the foundation is nutrient & caloric dense very bio-available foods. It also eliminates oxalates and lectins that can possibly worsen the B1 deficiency condition. Introducing safe healthy plants later on would be your best bet once you're able to get past the hump of this horrible condition
@@JYAN2852 Nonsense. The more foods one eliminates, the worse the condition gets. And besides, thiamine is one of the nutrients needed to help process oxalate. And GLUCOSE of all things, helps restore not only glycogen, but the mucin barrier of the gut lining.
Here's a case study where the anorexic patient's body temp didn't normalize until glucose was added to her thiamine...
www.metabolismjournal.com/article/0026-0495(83)90063-X/fulltext
@@DDumbrille While I respect your opinion there is one fact that we don't seem to consider. There is no such thing as an essential carb macronutrient to make glucose. The liver makes as much as the body needs via gluconeogenesis. We don't need to be stuffing ourselves full of it. In doing so and stripping all of the micronutrients is what caused Thiamine defiency in the first place.
@@JYAN2852 Gluconeogenesis is a catabolic process due to insufficient carbs. I don't know about you, but I've already lost too much muscle to go that route. The only thing that's finally helping me turn that around, is increasing carb intake. But you make a critical point -- and I agree -- we don't need to be 'stuffing ourselves full of it'. That's so true. But we also don't need to be avoiding it like it's a poison.
Does that means benfotiamine works temporarily and provides symptomatic relief only in dry beriberi patients? Please answer because i am suffering from it and I can't tolerate carbohydrate little bit
Pleased I found this video very imformative and I hope it helps me with my ongoing health problems.
If low thiamine can cause high pyruvate or high lactiate? What else helps body process with acetylcholine beside thiamine (reacted everytime tried to raise ACH)
I get high when I take thaimine idk why
its an intense euphoria its a bit much
im on carnivore for gut motility issues probably sibo
im 30
Is TTFD same as Allthiamine? Can thiamine defic cause blood to coagulate or be thicker or maybe just effect the endothium health? Sounds like diet, life, stress... effect thiamine and guessing genetics. Thanks Be Well ! TY to all for commenting as helpful for many!
Possibly epigenetics
Thank you very much for this video. My IBD doctors won't listen to me, this is very helpful in my research.
I look forward to the rest of the series !
Elliot, could you elaborate on why it is that some people that are thiamine deficient respond poorly to B vitamin complexes in general? I've found that high doses of folate (over about 400 mcg L-Methyltetrahydrofolate) seem to consistently lead to a very anxious state of mind along with some nerve pain.
For anyone who is curious, my case is incredibly similar to Case 3 in this video. Everything outlined there is almost exactly what I've experienced in the past when my issues were at their peak minus the excessive salivation.
The same thing
your genes may have been used to get b complex from bacteria and you could have lost that bacteria from antibiotics or any traditional doctors treatment medication/theraphy/procedures
Thank you Elliott.this video give me Hope
Excellent video I always learn a lot listening to you
This is now one of my top favorite videos on TH-cam! You are a wealth of knowledge. My 78 year old mother has been dealing with beriberi (or NA-WE) from a lifetime of eating white rice. She slipped and fell on some ice over the winter and has not been the same since. She has all of the classic symptoms of B1 deficiency as you talked about. The B-complex isn't cutting it and never knew about TFFD. I will buy a bottle of it today and start her off on 100mg/day along with 400mg magnesium glycinate. Will she also need the other B-vitamins? If yes, which brand and doseage would you recommend for someone with moderate beriberi?
Country life Benfothiamine or Nutritional Yeast, according to Dr. BERG
@@msroja2003 TTFD is a step above benfitiamine actually. I don't think Dr Berg is aware. TTFD is not only more effective but also pricier unfortunately. I recommend both to my clients depending on the situation. Both are great B1 options for temporary megadosing to overcome deficiencies
Really like the information . Maybe I should take more B complex. Is methylated B something to consider?
Superb. Gives hope.
As a diabetic type 1 for over 20 years now, Benfotiamin 150mg with keto helped me a lot
Do you still do consultation via online way? For ppl not in the U. K
Such a powerful video!
After being told countless times by multiple doctors that I was making my heart problems and dysautonomia symptoms up in my head and/or psyching myself out and bringing symptoms of POTS on(I wasn't even anxious and was told by 2 cardiologists that I was making myself anxious and causing tachycardia) I researched for about a decade never finding a cure for this nonsense. Traditional doctors can be absolutely blinkered and gormless. I found the whole experience bizarre. A grand total of 2 bleeding blood tests were ever done of all the doctors I visited the last decade. The tests were Iron and Thyroid function. Pathetic... I know people without health issues who have way more blood tests than I had, but my expensive doctors didn't issue anything intelligent to get to the bottom of my dysautonomia and fatigue. Bizarre. My uneducated high-school brain could have done better than that that the time...
I took matters into my own hands for the next decade and eventually discovered that the dysautonomia I had been experiencing was most likely the cause of low vitamin b1. This dysautonomia was absolutely exhausting and caused me a major setback in life. Every aspect of my life was slipping away. No energy, extreme tachycardia, mood disturbance and general misery. This all from having been a very happy person up to the "crash" as you refer to it.
Fast forward to 4 months ago. I finally start supplementing the ineffective HCL B1 form and already this helps. I then do more research and get hold of Sulbutiamine and this works nothing short of a miracle. Energy levels are coming back. Heart problems are waning significantly. Mental fog and mood disturbances are disappearing. I am starting to feel normal again. I never believed this possible... I have very little faith in doctors and quite frankly their work on me had been pathetic and it took me to fix the issue. A shame I wasn't told about b1 an entire decade ago by the expensive doctors and cardiologists I visited... Nothing...
I am now ordering Thiamine in the form of Tetrahydrofurfuryl Disulfide or TTFD, as that's where my research has lead after soaking up your amazing work. I can't thank you enough Elliot. It's lucky that I found your videos. I am getting back my quality of life that I had all along before this deficiency.
Looking forward to seeing a potential even further boost with TTFD. It's lucky that I have a scientific and research based mind, as I could imagine few other people have the patience and expertise to self-diagnose to the degree I did and it breaks my heart that such people are not getting the help that they need. We need more doctors who know the modern scientific literature and conduct the proper testing, but alas, science and pharmacology is always changing so doctors can often only be so knowledgeable. Still there is no excuse for gormless doctors. Perhaps the use of AI will help diagnosis in more fine resolution in the future where the measly brain of a doctor can't keep up! Pity some have to suffer for so long when the answer is there from the beginning.
Thanks for your amazing work Elliot!
I have had a similar experience to yours and I’m thankful for my research-based brain and ability to think outside the box. Doctors just don’t get it. Thank you for sharing your experience.
What is the best form of supplementation? I heard somewhere that it has to be in powder form. Something to do with the chemicals used to put in pill form was an issue for some reason. Is this true? Should I buy a standard B complex in the Super market? Prices can range greatly. What's the difference between cheaper ones and more expensive ones? This is could be a video subject. I have noticed times where I feel unusually cold.
I have several videos on it. Just go onto my channel and looks for videos on thiamine :)
Thank you!! Great video..and information!
Can I supplement with Thiamine HCL, Magnesium Chloride and D3 for thiamine deficiency? I’m reacting negatively to everything, will the low thiamine dosage still heal me?
Love your Videos Elliot, I have had symptoms of Thiamine deficiency for 3 years. (66 yrs old) I watched your video on Oxalates with Sally and went on a low ox diet and felt really good immediately for 3 weeks then the dumping started. The Benfo causes dumping and I cannot take high doses and still function. I'll just try to increase as I get better.
Sorry to hear that! Take it slow :)
What do you mean ... dumping?
@@tomregan9628 you need to look up talks on oxalates by Sally Norton. I’m sure Elliot also covers it somewhere too.
Will caffeine by itself also deplete thiamine while on a carnivore diet?
Just stop after a couple cups.
@@Keep-on-ok i take tablets 200mg
@@blink99v So that is approximately 2 cups, 8 oz each, brewed coffee.
Can someone tell me how much dosage to intake and what b1 form to take. I have gerd, dizziness air hunger sometimes and fatigue also anxiety
1500 mg B1 per day and I finally have some energy back. Taking the other B’s as well and Mg and potassium.
Thiamine HCL?
Yes thiamine HCL
I started taking Benfotiamine 300-600mg and then switched to TTFD 150mg about 2 weeks ago and my blood pressure is all over the place the sphygmomanometer won't even register numbers (shows error). I kind of feel better and worse at the same time, it's bizarre. Did you have troubles in the beginning too? How long did it take for you to feel better?
Beauty Psycho. Yes I had trouble in the beginning; it made me super hyper : heart racing, sweating, hyper alert. It scared the crap out of me. So I restarted and went up slower.
Any change in dose takes four days before I feel it. Because of that I made lots of mistakes in the beginning.
Benfotiamine gives me terrible pain. I don’t understand why.
I think my deficiency was caused by decades of overeating carbs combined with a very high stress life. I’m eating carnivore since oktober and my stress is much lower also.
I also have other deficiencies, I’m a right mess 😂. But I’m getting better because I understand the carb problem now.
@@violiendamast The funny thing is I felt a lot better on a Paleo diet than on Keto. And when I tried going carnivore recently, I almost felt like I need to go to ER! If higher carb diet increases the thiamine requirement, how come I feel so much worse without carbs?
I have just found your channel .... thank you so much for sharing the knowledge. I have had 3 times in my life (now 72 years) when my whole system collapsed. This last one has been the hardest for me and I am so grateful for finding this link to thiamine. Hopefully it will resolve the 2 autoimmune diseases I know I have and put me back on the road to recovery. 🙂 I have the rocks in my stomach sensation which makes turning over very difficult. Lemon water before going to bed helps. I think its a gas build up but it bruises the surrounding tissue.... very uncomfirtable.
Lemon water can irritate the stomach a lot.
@@JohnDoe-dy4kf I like lime in my water over lemon
For someone who has constipation, what is the best type of magnesium? Is it malate the best option? And what is the optimal dose? Thanks
Could a person avoid the 'worsening' of symptoms by cutting back and going slower?
Hello Elliot, thank You for sharing Your experience with Thiamine deficiencies. I wonder what one could do if the standard Thiamine supplements ( B1-HCl, Benfothiamine, TTFD) are not tolerated well ?
I was trying to overcome chronic fatigue working with all of those supplements (about 2-3 months) after being strict carnivore for about 6 months but my stomach clearly says No to them. I get terribly irritated and nervous even on low doses ? What would You suggest ?
Greetings from Germany *
Lots of possibilities. I see benfotiamine causing digestive issues in some people, whereas TTFD does not. On the other hand, many people don't tolerate TTFD.
It could be that thiamine is not you issue. Alternatively, it could be a dysbiosis issue.
Finally, irritation and nervousness are sometimes the ordinary signs of adaptation, and if cofactors are not taken in conjunction with the B1, it can cause these symptoms.
@@EONutrition Thank You for Your thoughts on the matter - my digestion is regular when I eat beaf and I do not have a past of gut issues. I took a B-Complex together with the TTFD and had similar issues when adding Mg-Citrate. My fatigue is mainly in the head and taking a Ziolith-Binder seems to improve my status. Maybe it´s rather an Oxalate issue... Appreciate Your advice, stay healthy ! *
Fairly new to Carnivore diet.. a couple months. I'm hooked on Coffee/Splenda/Half and Half, and got Nailed/Fooled by some Keto Snacks. Turned out to be Thiamine issue as you describe. If I have a "Bad" Keto Snack the night before (they come in 3's), the next morning, I have this Panic Attack thing.. I know something is wrong, sometimes BP goes up to 145/85, and I go into walk it out mode.. usually 10 times around the house. Worst case I have some Clonazapam (.25mg) which keeps from from calling the ambulance anyway. Seems to help if I eat the usual Eggs and bacon breakfast soon after I get up, and hold off coffee a bit. This morning I took a Vitamin B1 along with the usual Beet Root and Niacin. Wow.. took 45 minutes.. but it just went away!.. Looks like this could be the problem.. KETO SNACKs are for emergency use only.. I am pretty sensitive to any sugars/carbohydrates since carnivore. Carnivore diet kicked off the Coffee addiction which is being reduced.. Splenda is bubbling up to the top of the KICK IT list as well. A few Bumps in the road going Carnivore.. but clearly major improvements in every facit of my health Teeth, Hair, Skin, Mosquito Bites, Clarity, Motivation.. Wow..
Yes.. I'm taking Bentotimine(?) 600 mg.. form of B1.. works for me. Another symptom I had was while I was doing my house walking, I'd forget to breathe! I'd find myself almost gasping for breath! The Autonomic nervous system was Messed up.. What you say fit's my situation.
Greetings from USA. Than you thank you. You've described exactly what happened to me 20 years ago, after 23 years of vegetarianism. Wish I'd known you back then. All I got from doctors were tranquilizers. I had to figure it out myself. I just became aware of the Thiamine issue and am starting to take it since I still have some symptoms. Have heard that cocarboxylase chloride is the best form of it. What do you think?
I prefer to use TTFD, as this form does not require a transporter
Should one stop or minimize carbs when trying to fix Thamine deficiency? I'm doing Carnivore but I eat about 100g carbs at dinner for sleep and thyroid.
That's not Carnivore. Carnivore is basically meat and eggs seasoned with salt. Some people can tolerate a little dairy here and there. Broth. Healthy fats. Even with keto, the standard protocol is around 20 grams daily, usually from veggies. Oxalates and other chemicals from plants, can cause chronic health issues. This is one of the main reasons people choose to go Carnivore. To give their body a rest needed from plant consumption.
@@ThisIsNotMyHome Yes, I meant to say I ate Carnivore during the day, but not at dinner.
I've been drinking increasing amounts of sugary lattes the past few years and noticed I had declining health. I began to cut back because of the caffeine's effect on my sleep and energy levels, but noticed not the same improvement that I had the first time I consumed too much caffeine and reduced to a low intake. Then I got COVID, followed by some type of gastrointestinal infection, then RSV, and then some UTI/STI that I took antibiotics for. Kept getting worse after each event even though I kept improving my lifestyle and diet. Now I realize I was doing and having just about everything wrong (except alcohol abuse) for my thiamin levels, for years, and that COVID probably caused the crash.
I did the diet thing but didn`t get better. I just startet on Thiamine and now I am gaining weight. Also waiting for my order on benfothiamine 250 mg to arrive. Looking forward to it.
really interesting ive suffered from a lot of these symptoms and struggled with my weight I found extremely strict low carb to work well for me. I noticed a lot of the symptoms correlate with issues caused by thyroid , temperature regulation, weight management, chronic fatigue, libido problems etc are the two connected in someway?
cant answer that but it's something on my mind as well, they do seem like very similar symptoms
Look into iodine and selenium deficiency as well
Thank you Elliot you have saved my life. Omg I was living in mold and started drinking alot. Chest pains diareah etc...by a miricle I went to a demi lovato concert and started to heal based on I think the limbic system effect. Im very sick brain fog and gut disboisis mostly eat carnivore low fod maps foods and low oxalate foods. Low purine. No nightshades. Im doing better but how much of B1 should I take?
Hi, just discovered you and I think you are too smart for me. Question: is it ok to take high dose of thiamine without balancing out the other b vitamins? Or is that old science? Thank you 🙏
Best to take a B complex behind it :)
@@EONutrition ok thank you 🙏
Yes eat pork chops very high in B1
Mostly meat and fats have helped me tremendously with this but nothing like sulbutiamine!!! It’s the best thiamine you can get…day 1 of taking, I felt like a new woman.
And how are you now? Still taking it?
Nuked my thiamine for years without understanding how this worked. Coffee, tea, polyphenols, high vitamin A foods, alcohol, sugar. All reducing absorption, using it up, or binding it to aldehydes built up from slow ALDH. Cutting vision A was a huge step to fixing a lot of things but knowledge of thiamine is another game changer.
I did the exact same thing the past few years. Ever since I was a teenager really, but much worse the past couple years. Excited to get my Thiamax and begin the dosing protocol and see if it helps.
@@TheSpecialJ11 I found it had a sort of antidote effect. Helped me for a little bit and it did seem to cure my apnea but not sure if it's doing a lot for me anymore.
@@steverg2have you tried upping your dose?
I hade same as case 2. I have used tudca, omega 3 codliver oil, all 3sorts of thiamin, riboflavin, nicotin acid mostly lower dose. Magnesium citrate mostly, metyl b6, b9, b12 somedays higher dose, mct oil, kolin, vitamin a, c, d, k2, minerals tried alot. Kito somtimes carnivore helpt to survive for month before starting b1 therapi.
Can this be diagnosed through simple B1blood test? or is serum not reflective of tissue levels? Was on adderall for 6 years along with caffeine, and a high sugar/carb diet, poor nutrition... i had a organic acid test done as well which showed B12 deficiency [ adenyo/methyl] Can i look at markers via my OAT?
@@mello.b3373 that's what I assumed. They measure B12 via my OAT test and I known electrolytes arent exactly reflective in blood either.
There are a few markers on the OAT - 2oxoglutaric acid, Pyruvate, Lactate, 2-hydroxyisovaleric acid. However, these are sometimes "normal". Bloods are unreliable
@@EONutrition ty that's why I'm going more by my OAT. I had normal B2 but low B12. Also low molybdenum per my HTMA. Which is a co factor for b12 absorption. Would all those factors you mentioned be low?
@@blink99v No, they would usually be high.
However, usually only 1 or 2 are elevated
im considering this from the muscle twitches and weight loss. this was interesting
Wow, the chart at 18:45. I think that's exactly what happened to me.
What supplement of B1 fo you recommend
I get severe headaches from B1, but I literally have all those symptoms except I have 5 or 10 extra pounds around.
Does HIT/MCAS tie into this?
Did you try this?
I also have MCAS, bad GI issues, I’m going to try this
I have 7 symptoms. Do I need to be concerned?