Longevity and Aging in Humans

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  • เผยแพร่เมื่อ 3 มิ.ย. 2024
  • (May 4, 2010) Thomas Rando and Anne Brunet provide a general overview on the process and potential prevention of aging. The topics they cover vary from symptoms of aging to unusual characteristics that seem to prolong longevity.
    During the final quarter of the Stanford Mini Med School, some of the most timely and important topics in contemporary medicine and the biosciences are addressed.
    Stanford Mini Med School is a series arranged and directed by Stanford's School of Medicine and presented by the Stanford Continuing Studies program.
    Stanford University:
    www.stanford.edu
    Stanford Medical School:
    med.stanford.edu/
    Stanford Continuing Studies:
    continuingstudies.stanford.edu/
    Stanford University Channel on TH-cam:
    / stanford

ความคิดเห็น • 94

  • @howellwong11
    @howellwong11 2 ปีที่แล้ว +2

    At 70, I set my expected life span at 84. Now that I am 89. I have set it at 94. Soon it will be 100, I hope.

  • @Shaunt1
    @Shaunt1 9 ปีที่แล้ว

    A very important subject with useful info. I'd like to see more done in this field.

  • @hasilsembiringco-id222
    @hasilsembiringco-id222 2 ปีที่แล้ว

    what wonderful lectures. entering my sixties, I learn that these lectures are really useful. Thank you so much.

  • @rodeo179
    @rodeo179 13 ปีที่แล้ว +1

    the core of lecture (minus introductory graphs) starts @ 21:11
    thanks for posting!

    • @apexxxx10
      @apexxxx10 4 ปีที่แล้ว

      pelikan w 21:11 *Thanks *AGING an DRIVING. JOHN K. LINDGREN* th-cam.com/video/VOggAvPuLmM/w-d-xo.html

  • @Featureman
    @Featureman 13 ปีที่แล้ว +2

    I met Ronnie Fairbanks who claimed to be 107. He might have been. He was in excellent condition. I do have a video with him called Longevity. Your advice in this video and the study in general of aging factors is interesting and very important for each of us. Thanks.

  • @JohnJayRambo1
    @JohnJayRambo1 13 ปีที่แล้ว +9

    God numbered mans years to be 120 Genesis 6:3

    • @sleepsmartsmashstress740
      @sleepsmartsmashstress740 3 ปีที่แล้ว

      God never went to school He can only count to 10 with 5 on each hand not to 120

    • @wmp3346
      @wmp3346 2 ปีที่แล้ว

      God is a fictional character who probably does not exist. Learn ethics, fairness and empathy and you will be a better person

  • @nneichan9353
    @nneichan9353 2 ปีที่แล้ว

    Two of my favorite doctors were trained at Harvard (in the same class!).

  • @wvhdogg
    @wvhdogg 14 ปีที่แล้ว

    useful information

  • @TheBartBarton
    @TheBartBarton 9 ปีที่แล้ว +6

    This presentation completely ruined by an overly eager crowd interrupting the flow and competing with their questions. STFu and let him finish, then ask the questions.

  • @xtremetom180
    @xtremetom180 12 ปีที่แล้ว

    great vid you have here

  • @tonifelise6297
    @tonifelise6297 3 ปีที่แล้ว

    What ages and kills people is life, the kind of life you led, its very individual, some people get lucky and have more happiness so they live longer

  • @carrollhoagland1053
    @carrollhoagland1053 7 ปีที่แล้ว +3

    Interesting talks, as many are by passing doctors (they have no real training - just regurgitate other sciences) and trying to understand these topics. Doctors diagnose after we are sick, it is the patient who needs to be proactive. Therefore intervention in the aging process becomes the target ... Simple ... The AMA (the most powerful lobby in Washington) and NIH have failed the patient ... Physicians have abandoned the nutritional approach to patient diagnostics and medicine, simply because they are not trained in nutrition. A key part of the Hippocratic Oath ... “I will prevent disease whenever I can, for prevention is preferable to cure... “, has been forgotten …
    70 Going On 100 ... the Centenarian Diet

    • @dr.aardsmasvitamins8605
      @dr.aardsmasvitamins8605 4 ปีที่แล้ว

      Another perspective is that aging itself is a preventable disease, with a specific cure.

    • @wmp3346
      @wmp3346 2 ปีที่แล้ว

      What else is new, people are selfish and act in there self interest not others

  • @social3ngin33rin
    @social3ngin33rin 14 ปีที่แล้ว

    Enjoyed all 1 5/6th of an hour :)

  • @mjpucher
    @mjpucher 4 ปีที่แล้ว

    Dietary restriction will kill your metabolism if done wrong. You need to properly fast or intermittent fast with low carb and do High intensity resistance training to stop muscle loss.

  • @arttoegemann
    @arttoegemann 10 ปีที่แล้ว

    Growing young.
    Master aging at the genetic level.

  • @ImAnElephant89
    @ImAnElephant89 12 ปีที่แล้ว

    Penn Foster Herbal Studies sent me here!!!

  • @SinghTheMaster
    @SinghTheMaster 11 ปีที่แล้ว

    thanks :) you saved our 21 mins

    • @apexxxx10
      @apexxxx10 4 ปีที่แล้ว

      D Singh *”TIME” THAILAND INTERNATIONAL MOTOR EXPO* th-cam.com/video/EKTxwMPnV1M/w-d-xo.html

  • @frv6610
    @frv6610 7 ปีที่แล้ว

    at 48:00 Thomas mentions heterochronicity. did it increase lifespan of the older mouse? can the young mouse be genetically modified for connection with a human to rejuvenate the stem cells?

  • @adriatik7070
    @adriatik7070 11 ปีที่แล้ว +4

    with caloric restriction it just feels you living longer cause one is miserable and hungry …lol

    • @fordicidia6361
      @fordicidia6361 3 ปีที่แล้ว

      The pleasures of life are not merely culinary. We should eat to live, not live to eat.

  • @futuristiclettuce
    @futuristiclettuce 11 ปีที่แล้ว +1

    Believing in something out of fear, in your case believing in God because you fear going to hell, is not the right way to go about deciding what to believe in.

  • @cellhealer
    @cellhealer 8 ปีที่แล้ว

    my longevity club members saw this video and like s it , I work on longevity with my personal longevity machines

    • @Maxdud
      @Maxdud 7 ปีที่แล้ว +1

      That's Amazing!
      We have a discord server talking about longevity and there are actually people in the field who are scientists in longevity and have met these famous names!
      discord.gg/ftSbffu
      Here is the Link if you wanna join!

    • @cellhealer
      @cellhealer 7 ปีที่แล้ว

      I m actually Science Director in 2 research centers and in charge of Longevity developy machines

  • @colinmaharaj
    @colinmaharaj 3 ปีที่แล้ว

    1:01:27 Anne Brunet part

  • @lindacyoung1789
    @lindacyoung1789 2 ปีที่แล้ว

    Linda C Young.

  • @blacklegsanji3339
    @blacklegsanji3339 3 ปีที่แล้ว

    Im not so sure if there is muscle cells in the nervous system, i think that its actually the only place where there are non.

  • @beingnonbeing
    @beingnonbeing 9 ปีที่แล้ว

    What is the date of this lecture?

    • @colinmaharaj
      @colinmaharaj 9 ปีที่แล้ว +1

      beingnonbeing don't worry, it is still relevant :)

  • @grunder20
    @grunder20 12 ปีที่แล้ว

    No one can stop aging. It is nature.

    • @wmp3346
      @wmp3346 2 ปีที่แล้ว

      Not true

  • @Reynoldsrobert
    @Reynoldsrobert 5 ปีที่แล้ว

    When uploading a video with slide presentations, it's good to upload with AT LEAST 720P. (Many watch these presentations on their phone, although that doesn't matter). Even blowing up slide photos that are done at 480, the fine print cannot be read. (No matter how good your vision is)

    • @gs-nq6mw
      @gs-nq6mw 4 ปีที่แล้ว +1

      Lol,thats a 2010 video

  • @MrDeshrine
    @MrDeshrine 4 ปีที่แล้ว

    I recently did a 23andMe DNA test and found out I have the FOXO3A gene SNP(single nucleotide polymorphism) rs 2802292 (G;G) which is the exceptional longevity gene. I can't help but think that's due to the previous three years I've been practicing cyclic fasting 23h fast and 1h feeding in combination with caloric restriction. I also have engaged in both aerobic and resistance training for the entire duration. I feel as though this gene has been expressed through epigentic change. I'm quite excited to say the very least. I follow the Age Inhibition Regimen by Dr. Nun Amen Ra.

    • @blakehernandez1304
      @blakehernandez1304 3 ปีที่แล้ว +3

      What?? Your diet doesn’t affect your genetic code. Not unless you’re eating Uranium

    • @MrDeshrine
      @MrDeshrine 3 ปีที่แล้ว +1

      @@blakehernandez1304 Well, part of epigenetic genealogy is how we understand how nurture, or environment, can have an effect on nature, or genes for that matter. Particular genes can be expressed or turned on depending on chronic lifestyle choices and circumstances, like smoking and chronic stressors. Further, those newly expressed genes can be passed on to offspring, which is one of the best ways we can observe evolution of species. It's somewhere in that ballpark

    • @blakehernandez1304
      @blakehernandez1304 3 ปีที่แล้ว +1

      Deshrine Ussin i think you misunderstand the term “gene expression”. If a gene is expressed, it simply means that the protein corresponding to the gene is being produced. This does not alter your genetic code.

    • @MrDeshrine
      @MrDeshrine 3 ปีที่แล้ว

      @@blakehernandez1304 See, I never made the assertion that diet or lifestyle change genetic code, only expression. I understand epigenetics aren't relating to code sequence but gene activity. Most people possess the same genome, heredity, environment, and transgenerational epigenetic inheritance play a role in how they are expressed determining what alleles of specific genes one carries. Maybe I'm wrong, but that's how I understand it. For instance, chronic activation of AMPKinase, an enzyme that is active in caloric deficits and endurance training, can alter the expression of FOXO3A, in fact, those who do not inherit (G;G) alleles, can only alter FOXO3A through AMPKinase and inhibition of mTOR, and IGF-1.

    • @blakehernandez1304
      @blakehernandez1304 3 ปีที่แล้ว

      Deshrine Ussin my main comment was that your lifestyle and diet have nothing to do with you having a particular SNP in the FOXO3A gene. That is already determined when you’re born

  • @unclegrim
    @unclegrim 12 ปีที่แล้ว

    Stop asking questions and let the man finish his lecture, goddamn!

    • @jessiewest4153
      @jessiewest4153 5 ปีที่แล้ว

      Yes the asking of so many questions is very annoying.

  • @wmp3346
    @wmp3346 2 ปีที่แล้ว

    Pre IF?

  • @chunglee6895
    @chunglee6895 8 ปีที่แล้ว +1

    Stop those questions until the lecture is over!
    moderator is not doing his job.

  • @andrewlace55
    @andrewlace55 10 ปีที่แล้ว +1

    Start at 21 minutes!

  • @JohnJayRambo1
    @JohnJayRambo1 11 ปีที่แล้ว +1

    @playsbba018 better safe than sorry heaven and hell are real I pray you don't learn the hard way. And hell is a very scary place :((((

  • @astroboomboy
    @astroboomboy 11 ปีที่แล้ว

    Actually that is a statistical error. Because most people have faith on God(s), the comparison is between an extremely large group, and a very small group, which means that the average life span my be quite similar, but a larger group will have more likelihood of more people living longer. I remember reading this quite recently by a statistician, which I remembered where.

  • @davidtraversa
    @davidtraversa 11 ปีที่แล้ว +1

    Astroboomboy. You should check your statistics. In Germany the church --evangelists and christians-- have sold 400 temples already because people are stoping in droves going to churches and the business is no good anymore, 150.000 people a year are leaving religion because with more education, they are seeing the flimsy fairytale they had been told for centuries of ignorance.
    Try watching some very fascinating people on the Internet that will explain you some issues in very easy talks.

  • @theequaliser8026
    @theequaliser8026 3 ปีที่แล้ว

    Umm

  • @Reynoldsrobert
    @Reynoldsrobert 5 ปีที่แล้ว +1

    I wonder how much of the first doubling in life span which happened over many thousands of years was due to the ratio of mega fauna predators to humans changing over time. Traditional archaeology says it took us a million years to VERY SLIGHTLY improve sharpened stones, so they have little claim to lay that it had anything to do with technology. (Traditional archaeologists are, unbeknownst to them, the world's foremost experts in brain washing, if only by experience! Haha, after all, anyone presented those theories that hadn't had their common sense somehow dramatically weakened, would know better! But that is what our educational system is focused on, BRAIN WASHING!)

  • @guestuser2373
    @guestuser2373 5 ปีที่แล้ว +1

    She can say DZZs to me any day.

  • @JohnJayRambo1
    @JohnJayRambo1 13 ปีที่แล้ว

    I have many physical proofs that God is real. When you die my friend you are going to answer to our creator. You will have no excuses. God will remind you of this comment. I pray and cover you with the fear of God bringing you to a place of repentance. God is awesome my friend he created us and loves us more than we know on this lifetime. I leave you with this beloved.

  • @life42theuniverse
    @life42theuniverse ปีที่แล้ว

    Hmm, So vampirism is a way to live a long life. Consuming the blood of the young...

  • @happyandhealthy888
    @happyandhealthy888 2 ปีที่แล้ว

    aGING AND LONGEVITy

  • @defenderoftheadverb
    @defenderoftheadverb 11 ปีที่แล้ว +2

    There's a statistical correlation indicating people of faith live longer too. Trouble is belief is not qualified by need or virtue. You either believe in god or you don't. There is no rational proof. Those who believe do so irrationally.

    • @RaffiTheQuokka
      @RaffiTheQuokka 2 ปีที่แล้ว

      Well, I think prayer and meditation are very similar, and this mechanism has significant benefits (lower stress hormones, better sleep...)

  • @JohnJayRambo1
    @JohnJayRambo1 13 ปีที่แล้ว +1

    Believe in your creator he loves you. True longevity is being focused on the kingdom of heaven (eternal life) if you want me to share how I seen physical proof that God is real send me a message I will be more than happy to share with you. God Bless you and your family my friend

    • @wmp3346
      @wmp3346 2 ปีที่แล้ว

      Opinion with no evidence

  • @apexxxx10
    @apexxxx10 4 ปีที่แล้ว

    *Kiitos erittäin hyvä luento!*
    Bangkok -Jomppa* th-cam.com/video/EKTxwMPnV1M/w-d-xo.html

  • @ELZOOL12
    @ELZOOL12 12 ปีที่แล้ว

    I cannot believe how rude these students are. Ask your questions after a presentation. Give the guy a chance to fully explain himself before you interrupt him.

  • @dysvanlist
    @dysvanlist 13 ปีที่แล้ว

    @JohnJayRambo1 Why didn't you link this to my comment? I would have never seen it if I didn't check. As for your comment. I'm very sorry my friend, but you've been brainwashed with metaphysical nonsense. If you want to present your physical evidence, please present them with a personal message.

  • @JohnJayRambo1
    @JohnJayRambo1 13 ปีที่แล้ว

    Lets just say your right God does not exist. So when we all die that's it we die. We have nothing to worry about right? The believer and the unbeliever, however let's just say that your wrong :x God does exist and there is heaven for the believer and hell for the unbeliever. My point is that if your right I have nothing to loose either way. I'm in a win , win situation , and if your wrong your in a world of Hell :( I pray to God that you will see the hand of God like I did and believe in Him

  • @kotyto
    @kotyto 8 ปีที่แล้ว

    Another *** ranting "oxidative stress". Hehehe maybe mayflies or turtles are subject to a different regime environmental stress :-(

  • @TjenkinsandAige
    @TjenkinsandAige 13 ปีที่แล้ว

    "evolutionary design"? : oxymorom.

  • @kotyto
    @kotyto 8 ปีที่แล้ว

    He is misinformed. We seem to know why very old individuals die eventually. Seems a very old autopsied individual, had only a few stem cells renewing her body for about 5 years :-)

  • @TjenkinsandAige
    @TjenkinsandAige 13 ปีที่แล้ว

    "evolutionary design"? : oxymoron.

  • @pauljones5066
    @pauljones5066 4 ปีที่แล้ว

    live a long and miserable life folks

    • @wmp3346
      @wmp3346 2 ปีที่แล้ว

      Watch Fox News

  • @suzibelle3995
    @suzibelle3995 2 ปีที่แล้ว

    A recitation of a long-list of boring statistics is of no practical use to anyone seeking to live longer. Thomas Rando is a narcissist in love with his own superiority complex.

  • @dysvanlist
    @dysvanlist 13 ปีที่แล้ว

    @JohnJayRambo1 God doesn't exist